Molecular modeling reveals binding interface of γ-tubulin with GCP4 and interactions with noscapinoids

Proteins: Structure, Function and Bioinformatics

Volumn 83, Issue 5, 2015, Pages 827-843

  Suri, Charu ^a   Joshi, Harish C ^b   Naik, Pradeep Kumar ^a  

^a JAYPEE UNIVERSITY OF INFORMATION TECHNOLOGY   (India)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alanine scanning mutagenesis; Gamma complex proteins; Microtubule organization center; MM PBSA MM GBSA; Molecular dynamics; Molecular modeling; Noscapinoids; tubulin

Indexed keywords

ALANINE; GAMMA COMPLEX PROTEIN4; GAMMA TUBULIN; NOSCAPINE; NOSCAPINOID DERIVATIVE; UNCLASSIFIED DRUG; MICROTUBULE ASSOCIATED PROTEIN; PROTEIN BINDING; TUBGCP4 PROTEIN, HUMAN; TUBULIN;

ARTICLE; CRYSTAL STRUCTURE; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; ANALOGS AND DERIVATIVES; CHEMISTRY; HUMAN; HYDROGEN BOND; PROTEIN DOMAIN; THERMODYNAMICS;

HUMANS; HYDROGEN BONDING; MICROTUBULE-ASSOCIATED PROTEINS; MOLECULAR DOCKING SIMULATION; MOLECULAR DYNAMICS SIMULATION; NOSCAPINE; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; THERMODYNAMICS; TUBULIN;

EID: 84927695391     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.24773     Document Type: Article

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