Modeling the effect of codon translation rates on co-translational protein folding mechanisms of arbitrary complexity

Journal of Chemical Physics

Volumn 142, Issue 14, 2015, Pages

  Caniparoli, Luca ^a   O'Brien, Edward P ^b  

^a SISSA   (Italy)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CHAINS; COMPUTATIONAL CHEMISTRY; COMPUTATIONAL EFFICIENCY; MARKOV PROCESSES; MOLECULAR DYNAMICS; PROTEIN FOLDING; PROTEINS; SYNTHESIS (CHEMICAL);

COMPUTATIONAL APPROACH; COMPUTATIONAL STUDIES; FAR-FROM-EQUILIBRIUM PROCESS; FUNCTIONAL CONFORMATIONS; MOLECULAR DYNAMICS SIMULATIONS; PROTEIN FOLDING MECHANISMS; TERTIARY STRUCTURES; THEORETICAL FRAMEWORK;

BIOSYNTHESIS;

CODON; PROTEIN;

BIOLOGICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; CODON; GENETICS; KINETICS; PROBABILITY; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN SYNTHESIS;

CODON; KINETICS; MARKOV CHAINS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; PROTEIN BIOSYNTHESIS; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEINS;

EID: 84927659786     PISSN: 00219606     EISSN: None     Source Type: Journal    
DOI: 10.1063/1.4916914     Document Type: Article

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47. See supplementary material at http://dx.doi.org/10.1063/1.4916914 E-JCPSA6-142-027514 for implementation of Eq. (10) in Matlab code and a Charmm script for simulating continuous translation of a nascent protein.