Spreading depolarization in the brainstem mediates sudden cardiorespiratory arrest in mouse SUDEP models

Science Translational Medicine

Volumn 7, Issue 282, 2015, Pages

  Aiba, Isamu ^a   Noebels, Jeffrey L ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; POTASSIUM CHANNEL KV1.1; SODIUM CHANNEL NAV1.1; TAU PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; BRAIN STEM; CARDIOPULMONARY INSUFFICIENCY; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; DEPOLARIZATION; DIRECT CURRENT; DISEASE ASSOCIATION; DORSAL MEDULLA; ELECTROENCEPHALOGRAM; EVOKED BRAIN STEM RESPONSE; FEMALE; GENE FUNCTION; GENE IDENTIFICATION; HEART FUNCTION; IN VITRO STUDY; LUNG FUNCTION; MALE; MOLECULAR DYNAMICS; MOUSE; NERVE CELL NETWORK; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN FUNCTION; RISK ASSESSMENT; RISK FACTOR; SPREADING CORTICAL DEPRESSION; SPREADING DEPOLARIZATION; SUDDEN DEATH; ACTION POTENTIAL; AGING; ANIMAL; C57BL MOUSE; COMPLICATION; DISEASE MODEL; ELECTROENCEPHALOGRAPHY; GENETICS; HEART ARREST; KNOCKOUT MOUSE; METABOLISM; MUTATION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SEIZURE;

ACTION POTENTIALS; AGING; ANIMALS; BRAIN STEM; DEATH, SUDDEN; DISEASE MODELS, ANIMAL; ELECTROENCEPHALOGRAPHY; HEART ARREST; KV1.1 POTASSIUM CHANNEL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTATION; SEIZURES; TAU PROTEINS;

EID: 84927622806     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aaa4050     Document Type: Article

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