Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding module

Cell Research

Volumn 24, Issue 12, 2014, Pages 1433-1444

  Wang, Hui ^a,b   Curran, Elizabeth C ^a   Hinds, Thomas R ^a,b   Wang, Edith H ^a   Zheng, Ning ^a,b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

cell cycle progression; DNA binding; TAF; TFIID; Transcription; winged helix

Indexed keywords

CRICETINAE; EUKARYOTA;

DNA; HISTONE ACETYLTRANSFERASE; TAF7 PROTEIN, HUMAN; TATA BINDING PROTEIN ASSOCIATED FACTOR; TATA-BINDING PROTEIN ASSOCIATED FACTOR 250 KDA; TRANSCRIPTION FACTOR IID;

AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; HAMSTER; HUMAN; METABOLISM; MOLECULAR GENETICS; PROMOTER REGION; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL LINE; CRICETINAE; CRYSTALLOGRAPHY, X-RAY; DNA; HISTONE ACETYLTRANSFERASES; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS, GENETIC; PROTEIN CONFORMATION; TATA-BINDING PROTEIN ASSOCIATED FACTORS; TRANSCRIPTION FACTOR TFIID;

EID: 84927577473     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2014.148     Document Type: Article

References (40)

1. Thomas MC, Chiang CM. The general transcription machinery and general cofactors. Crit Rev Biochem Mol Biol 2006; 41: 105-178.
2. Gr?nberg S, Hahn S. Structural insights into transcription initiation by RNA polymerase II. Trends Biochem Sci 2013; 38: 603-611.
3. Buratowski S, Hahn S, Guarente L, Sharp PA. Five intermediate complexes in transcription initiation by RNA polymerase II. Cell 1989; 56: 549-561.
4. Van Dyke MW, Roeder RG, Sawadogo M. Physical analysis of transcription preinitiation complex assembly on a class II gene promoter. Science 1988; 241: 1335-1338.
5. Papai G, Weil PA, Schultz P. New insights into the function of transcription factor TFIID from recent structural studies. Curr Opin Genet Dev 2011; 21: 219-224.
6. Pugh BF, Tjian R. Transcription from a TATA-less promoter requires a multisubunit TFIID complex. Genes Dev 1991; 5: 1935-1945.
7. Tanese N, Pugh BF, Tjian R. Coactivators for a proline-rich activator purified from the multisubunit human TFIID complex. Genes Dev 1991; 5: 2212-2224.
8. Wassarman DA, Sauer F. TAF(II)250: a transcription toolbox. J Cell Sci 2001; 114: 2895-2902.
9. Mizzen CA, Yang XJ, Kokubo T, et al. The TAF(II)250 subunit of TFIID has histone acetyltransferase activity. Cell 1996; 87: 1261-1270.
10. Dikstein R, Ruppert S, Tjian R. TAFII250 is a bipartite protein kinase that phosphorylates the base transcription factor RAP74. Cell 1996; 84: 781-790.
11. Ruppert S, Tjian R. Human TAFII250 interacts with RAP74: implications for RNA polymerase II initiation. Genes Dev 1995; 9: 2747-2755.
12. Jacobson RH, Ladurner AG, King DS, Tjian R. Structure and function of a human TAFII250 double bromodomain module. Science 2000; 288: 1422-1425.
13. Cianfrocco MA, Kassavetis GA, Grob P, et al. Human TFIID binds to core promoter DNA in a reorganized structural state. Cell 2013; 152: 120-131.
14. Hisatake K, Hasegawa S, Takada R, Nakatani Y, Horikoshi M, Roeder RG. The p250 subunit of native TATA box-binding factor TFIID is the cell-cycle regulatory protein CCG1. Nature 1993; 362: 179-181.
15. Ruppert S, Wang EH, Tjian R. Cloning and expression of human TAFII250: a TBP-associated factor implicated in cell-cycle regulation. Nature 1993; 362: 175-179.
16. Hayashida T, Sekiguchi T, Noguchi E, Sunamoto H, Ohba T, Nishimoto T. The CCG1/TAFII250 gene is mutated in thermosensitive G1 mutants of the BHK21 cell line derived from golden hamster. Gene 1994; 141: 267-270.
17. Hilton TL, Li Y, Dunphy EL, Wang EH. TAF1 histone acetyl transferase activity in Sp1 activation of the cyclin D1 promoter. Mol Cell Biol 2005; 25: 4321-4332.
18. Chiang CM, Roeder RG. Cloning of an intrinsic human TFIID subunit that interacts with multiple transcriptional activators. Science 1995; 267: 531-536.
19. Lavigne AC, Mengus G, May M, et al. Multiple interactions between hTAFII55 and other TFIID subunits. Requirements for the formation of stable ternary complexes between hTAFII55 and the TATA-binding protein. J Biol Chem 1996; 271: 19774-19780.
20. Bhattacharya S, Lou X, Hwang P, et al. Structural and functional insight into TAF1-TAF7, a subcomplex of transcription factor II D. Proc Natl Acad Sci USA 2014; 111: 9103-9108.
21. Weissman JD, Brown JA, Howcroft TK, et al. HIV-1 tat binds TAFII250 and represses TAFII250-dependent transcription of major histocompatibility class I genes. Proc Natl Acad Sci USA 1998; 95: 11601-11606.
22. Dunphy EL, Johnson T, Auerbach SS, Wang EH. Requirement for TAF(II)250 acetyltransferase activity in cell cycle progression. Mol Cell Biol 2000; 20: 1134-1139.
23. Gaiser F, Tan S, Richmond TJ. Novel dimerization fold of RAP30/RAP74 in human TFIIF at 1.7 ? resolution. J Mol Biol 2000; 302: 1119-1127.
24. Shaban NM, Harvey S, Perrino FW, Hollis T. The structure of the mammalian RNase H2 complex provides insight into RNA.NA hybrid processing to prevent immune dysfunction. J Biol Chem 2010; 285: 3617-3624.
25. Geiger SR, Lorenzen K, Schreieck A, et al. RNA polymerase I contains a TFIIF-related DNA-binding subcomplex. Mol Cell 2010; 39: 583-594.
26. Taylor NM, Baudin F, von Scheven G, M?ller CW. RNA polymerase III-specific general transcription factor IIIC contains a heterodimer resembling TFIIF Rap30/Rap74. Nucleic Acids Res 2013; 41: 9183-9196.
27. Teichmann M, Dumay-Odelot H, Fribourg S. Structural and functional aspects of winged-helix domains at the core of transcription initiation complexes. Transcription 2012; 3: 2-7.
28. Gajiwala KS, Burley SK. Winged helix proteins. Curr Opin Struct Biol 2000; 10: 110-116.
29. Zheng N, Fraenkel E, Pabo CO, Pavletich NP. Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP. Genes Dev 1999; 13: 666-674.
30. Lee DH, Gershenzon N, Gupta M, Ioshikhes IP, Reinberg D, Lewis BA. Functional characterization of core promoter elements: the downstream core element is recognized by TAF1. Mol Cell Biol 2005; 25: 9674-9686.
31. Chalkley GE, Verrijzer CP. DNA binding site selection by RNA polymerase II TAFs: a TAF(II)250-TAF(II)150 complex recognizes the initiator. EMBO J 1999; 18: 4835-4845.
32. Juven-Gershon T, Cheng S, Kadonaga JT. Rational design of a super core promoter that enhances gene expression. Nat Methods 2006; 3: 917-922.
33. Zhao S, Choi M, Overton JD, et al. Landscape of somatic single- nucleotide and copy-number mutations in uterine serous carcinoma. Proc Natl Acad Sci USA 2013; 110: 2916-2921.
34. Kloet SL, Whiting JL, Gafken P, Ranish J, Wang EH. Phosphorylation- dependent regulation of cyclin D1 and cyclin A gene transcription by TFIID subunits TAF1 and TAF7. Mol Cell Biol 2012; 32: 3358-3369.
35. Gegonne A, Weissman JD, Singer DS. TAFII55 binding to TAFII250 inhibits its acetyltransferase activity. Proc Natl Acad Sci USA 2001; 98: 12432-12437.
36. Devaiah BN, Lu H, Gegonne A, et al. Novel functions for TAF7, a regulator of TAF1-independent transcription. J Biol Chem 2010; 285: 38772-38780.
37. Marmorstein R, Trievel RC. Histone modifying enzymes: structures, mechanisms, and specificities. Biochim Biophys Acta 2009; 1789: 58-68.
38. Otwinowski Z, Minor W. eds. Processing of X-ray Diffraction Data Collected in Oscillation Mode. New York: Academic Press 1997.
39. Adams PD, Grosse-Kunstleve RW, Hung LW, et al. PHENIX: building new software for automated crystallographic structure determination. Acta Crystallogr D Biol Crystallogr 2002; 58: 1948-1954.
40. CCP4. The CCP4 Suite: programs for protein crystallography. Acta Crystallogr D Biol Crystallogr 1994; D50: 760-763.