The role of contrast-enhanced ultrasound (CEUS) in visualizing atherosclerotic carotid plaque vulnerability: Which injection protocol? Which scanning technique?

European Journal of Radiology

Volumn 84, Issue 5, 2015, Pages 865-871

  Iezzi, Roberto ^a   Petrone, Gianluigi ^a   Ferrante, Angela ^a   Lauriola, Libero ^a   Vincenzoni, Claudio ^a   La Torre, Michele Fabio ^a   Snider, Francesco ^a   Rindi, Guido ^a   Bonomo, Lorenzo ^a  

^a CATHOLIC UNIVERSITY   (Italy)

Author keywords

Carotid plaque; CEUS; Dynamic imaging; Late phase imaging; Vulnerable plaque

Indexed keywords

SONOVUE; CONTRAST AGENT BR1; CONTRAST MEDIUM; PHOSPHOLIPID; SULFUR HEXAFLUORIDE;

AGED; ARTICLE; ASYMPTOMATIC DISEASE; CARDIOVASCULAR PARAMETERS; CAROTID ATHEROSCLEROSIS; CAROTID ENDARTERECTOMY; COMPUTER PROGRAM; CONTRAST ENHANCED ULTRASOUND; CONTRAST ENHANCEMENT; DIAGNOSTIC ACCURACY; ECHOGRAPHY; FEMALE; GOLD STANDARD; HISTOLOGY; HUMAN; IMMUNOHISTOLOGY; MAJOR CLINICAL STUDY; MALE; PLAQUE VULNERABILITY; PREDICTIVE VALUE; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; SENSITIVITY AND SPECIFICITY; VIDEOTAPE; CAROTID STENOSIS; DIAGNOSTIC USE; INJECTION; MIDDLE AGED; PLAQUE, ATHEROSCLEROTIC; PROCEDURES;

AGED; CAROTID STENOSIS; CONTRAST MEDIA; ENDARTERECTOMY, CAROTID; FEMALE; HUMANS; INJECTIONS; MALE; MIDDLE AGED; PHOSPHOLIPIDS; PLAQUE, ATHEROSCLEROTIC; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; SULFUR HEXAFLUORIDE; ULTRASONOGRAPHY;

EID: 84927568340     PISSN: 0720048X     EISSN: 18727727     Source Type: Journal    
DOI: 10.1016/j.ejrad.2015.01.024     Document Type: Article

References (31)

1. V.L. Roger, A.S. Go, and D.M. Lloyd-Jones Heart disease and stroke statistics-2011 update: a report from the American Heart Association Circulation 123 4 2011 e18 e209 [Errata published in Circulation 2011; 123(6):e240 and Circulation 2011; 124(16):e426]
2. D. Inzitari, M. Eliasziw, and P. Gates The causes and risk of stroke in patients with asymptomatic internal-carotid-artery stenosis, North American Symptomatic Carotid Endarterectomy Trial Collaborators N Engl J Med 342 23 2000 1693 1700
3. S. MacMahon, N. Sharpe, and G. Gamble Effects of lowering average of below-average cholesterol levels on the progression of carotid atherosclerosis: results of the LIPID Atherosclerosis Substudy. LIPID Trial Research Circulation 97 18 1998 1784 1790
4. J. Kang, M.F. Conrad, and V.I. Patel Clinical and anatomic outcomes after carotid endarterectomy J Vasc Surg 59 2014 944 949
5. J. Narula, and H.W. Strauss The popcorn plaques Nat Med 13 5 2007 532 534
6. R. Virmani, F.D. Kolodgie, and A.P. Burke Atherosclerotic plaque progression and vulnerability to rupture: angiogenesis as a source of intraplaque hemorrhage Arterioscler Thromb Vasc Biol 25 10 2005 2054 2061
7. R. Di Stefano, F. Felice, and A. Balbarini Angiogenesis as risk factor for plaque vulnerability Curr Pharm Des 15 10 2009 1095 1106
8. F. Joshi, D. Rosenbaum, and S. Bordes Vascular imaging with positron emission tomography J Intern Med 270 2 2011 99 109
9. R. Corti, and V. Fuster Imaging of atherosclerosis: magnetic resonance imaging Eur Heart J 32 14 2011 1709 1719
10. J.A. Schaar, F. Mastik, and E. Regar Current diagnostic modalities for vulnerable plaque detection Curr Pharm Des 13 10 2007 995 1001
11. S.B. Feinstein Contrast ultrasound imaging of the carotid artery vasa vasorum and atherosclerotic plaque neovascularization J Am Coll Cardiol 48 2 2006 236 243
12. S. Coli, M. Magnoni, and G. Sangiorgi Contrast-enhanced ultrasound imaging of intraplaque neovascularization in carotid arteries: correlation with histology and plaque echogenicity J Am Coll Cardiol 52 3 2008 223 230
13. M.F. Giannoni, E. Vicenzini, and M. Citone Contrast carotid ultrasound for the detection of unstable plaques with neoangiogenesis: a pilot study Eur J Vasc Endovasc Surg 37 6 2009 722 727
14. D. Staub, S. Partovi, and A.F. Schinkel Correlation of carotid artery atherosclerotic lesion echogenicity and severity at standard US with intraplaque neovascularization detected at contrast-enhanced US Radiology 258 2 2011 618 626
15. G.L. Faggioli, R. Pini, and R. Mauro Identification of carotid 'vulnerable plaque' by contrast-enhanced ultrasonography: correlation with plaque histology, symptoms and cerebral computed tomography Eur J Vasc Endovasc Surg 41 2 2011 238 248
16. G.L. Ten Kate, S.C. van den Oord, and E.J. Sijbrands Current status and future developments of contrast-enhanced ultrasound of carotid atherosclerosis J Vasc Surg 57 2 2013 539 546
17. W. Peeters, W.E. Hellings, and D.P. de Kleijn Carotid atherosclerotic plaques stabilize after stroke: insights into the natural process of atherosclerotic plaque stabilization Arterioscler Thromb Vasc Biol 29 1 2009 128 133
18. P.E. Shrout, and J.L. Fleiss Intraclass correlations: uses in assessing rater reliability Psychol Bull 86 2 1979 420 428
19. B. Rosner Fundamentals of biostatistics 1995 Duxbury New York, NY 420 426
20. A.P. Burke, F.D. Kolodgie, and A. Farb Morphological predictors of arterial remodeling in coronary atherosclerosis Circulation 105 3 2002 297 303
21. A.M. Varnava, P.G. Mills, and M.J. Davies Relationship between coronary artery remodeling and plaque vulnerability Circulation 105 8 2002 939 943
22. D.R. Owen, J. Shalhoub, and S. Miller Inflammation within carotid atherosclerotic plaque: assessment with late-phase contrast-enhanced US Radiology 255 2 2010 638 644
23. A. Hoogi, D. Adam, and A. Hoffman Carotid plaque vulnerability: quantification of neovascularization on contrast-enhanced ultrasound with histopathologic correlation AJR Am J Roentgenol 196 2 2011 431 436
24. North American Symptomatic Carotid Endarterectomy Trial Collaborators Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis N Engl J Med 325 1991 445 453
25. P.M. Rothwell, M. Eliasziw, and S.A. Gutnikov Analysis of pooled data from the randomised controlled trials of endarterectomy for symptomatic carotid stenosis Lancet 361 2003 107 116
26. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study Endarterectomy for asymptomatic carotid artery stenosis J Am Med Assoc 273 1995 1421 1428
27. European Carotid Surgery Trialists' Collaborative Group Randomised trial of endarterectomy for recently symptomatic carotid stenosis: final results of the MRC European Carotid Surgery Trial (ECST) Lancet 351 1998 1379 1387
28. F. Piscaglia, L. Bolondi Italian Society for Ultrasound in Medicine and Biology (SIUMB) Study Group on Ultrasound Contrast Agents The safety of Sonovue in abdominal applications: retrospective analysis of 23,188 investigations Ultrasound Med Biol 32 9 2006 1369 1375
29. A. Thapar, J. Shalhoub, and M. Averkiou Dose-dependent artifact in the far wall of the carotid artery at dynamic contrast-enhanced US Radiology 262 2 2012 672 679
30. J.F. Polak, L. Shemanski, and D.H. O'Leary Hypoechoic plaque at US of the carotid artery: an independent risk factor for incident stroke in adults aged 65 years or older. Cardiovascular Health Study Radiology 208 3 1998 649 654
31. M. Reiter, I. Effenberger, and S. Sabeti Increasing carotid plaque echolucency is predictive of cardiovascular events in high-risk patients Radiology 248 2008 1050 1055