Aging-associated formaldehyde-induced norepinephrine deficiency contributes to age-related memory decline

Aging Cell

Volumn 14, Issue 4, 2015, Pages 659-668

  Mei, Yufei ^a,b   Jiang, Chun ^c   Wan, You ^c   Lv, Jihui ^d   Jia, Jianping ^a   Wang, Xiaomin ^a   Yang, Xu ^b   Tong, Zhiqian ^a  

^a BEIJING INSTITUTE FOR BRAIN DISORDERS   (China)

^b CENTRAL CHINA NORMAL UNIVERSITY   (China)

^c PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^d Beijing Geriatric Hospital   (China)

Author keywords

Formaldehyde; Long term potentiation; Norepinephrine; Senescence accelerated prone 8; Spatial memory; Spontaneous discharge

Indexed keywords

FORMALDEHYDE; NORADRENALIN; OXIDOPAMINE; DOPAMINE BETA MONOOXYGENASE;

ADULT; AGING; ALZHEIMER DISEASE; AMNESIA; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMICAL ANALYSIS; CONTROLLED STUDY; DNA DEMETHYLATION; ESCAPE LATENCY; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPAL SLICE; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; LONG TERM POTENTIATION; MALE; MORRIS WATER MAZE TEST; NERVE CELL PLASTICITY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; SENESCENCE; SPATIAL LEARNING; SPATIAL MEMORY; SWIMMING SPEED; VISION; ANIMAL; AUTONOMIC NEUROPATHY; CHEMICALLY INDUCED; DEFICIENCY; DRUG EFFECTS; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MAZE TEST; MEMORY DISORDER; METABOLISM; MOUSE; PATHOLOGY; SPRAGUE DAWLEY RAT; STEREOTACTIC PROCEDURE;

AGING; ANIMALS; AUTONOMIC NERVOUS SYSTEM DISEASES; DOPAMINE BETA-HYDROXYLASE; FORMALDEHYDE; HIPPOCAMPUS; INJECTIONS, INTRAVENTRICULAR; LONG-TERM POTENTIATION; MALE; MAZE LEARNING; MEMORY DISORDERS; MICE; NOREPINEPHRINE; OXIDOPAMINE; RATS; RATS, SPRAGUE-DAWLEY; STEREOTAXIC TECHNIQUES;

EID: 84927546001     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12345     Document Type: Article

References (45)

1. Almaguer-Melian W, Rojas-Reyes Y, Alvare A, Rosillo JC, Frey JU, Bergado JA (2005) Long-term potentiation in the dentate gyrus in freely moving rats is reinforced by intraventricular application of norepinephrine, but not oxotremorine. Neurobiol. Learn. Mem. 83, 72-78.
2. Bliss TV, Errington ML (1984) Impaired long-term potentiation in the dentate gyrus of the reeler mutant mouse. J. Physiol. (Lond) 350, 15.
3. Chan-Palay V, Asan E (1989) Alterations in catecholamine neurons of the locus coeruleus in senile dementia of the Alzheimer type and in Parkinson’s disease with and without dementia and depression. J. Comp. Neurol. 287, 373-392.
4. Chouliaras L, Mastroeni D, Delvaux E, Grover A, Kenis G, Hof PR, Steinbusch HW, Coleman PD, Rutten BP, van den Hove DL (2013) Consistent decrease in global DNA methylation and hydroxymethylation in the hippocampus of Alzheimer’s disease patients. Neurobiol. Aging 34, 2091-2099.
5. Collier TJ, Gash DM, Sladek JR (1988) Transplantation of norepinephrine neurons into aged rats improves performance of a learned task. Brain Res. 448, 77-87.
6. Collier TJ, Gash DM, Felten DL, Stevens SY, Collier KS (2004) Reduced cortical noradrenergic neurotransmission is associated with increased neophobia and impaired spatial memory in aged rats. Neurobiol. Aging 25, 209-221.
7. Ehrlich M (2009) DNA hypomethylation in cancer cells. Epigenomics 1, 239-259.
8. Einarsson P, Hallman H, Jonsson G (1975) Quantitative microfluorimetry of formaldehyde induced fluorescence of dopamine in the caudate nucleus. Med. Biol. 53, 15-24.
9. Feng J, Zhou Y, Campbell SL, Le T, Li E, Sweatt JD, Silva AJ, Fan G (2010) Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat. Neurosci. 13, 423-430.
10. Francis BM, Yang J, Hajderi E, Brown ME, Michalski B, McLaurin J, Fahnestock M, Mount HT (2012) Reduced tissue levels of noradrenaline are associated with behavioral phenotypes of the TgCRND8 mouse model of Alzheimer’s disease. Neuropsychopharmacology 37, 1934-1944.
11. Gelinas JN, Nguyen PV (2007) Neuromodulation of hippocampal synaptic plasticity, learning, and memory by noradrenaline. Cent. Nerv. Syst. Agents Med. Chem. 7, 17-33.
12. Gray R, Johnston D (1987) Noradrenaline and beta-adrenoceptor agonists increase activity of voltage-dependent calcium channels in hippocampal neurons. Nature 327, 620-622.
13. Guo Y, Yang J, Wu X, Du A (2005) A sensitive fluorimetric method for the determination of epinephrine. J. Fluoresc. 15, 131-136.
14. Guo JU, Sun Y, Zhong C, Ming GL, Song H (2011) Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell 145, 423-434.
15. Hatfield T, McGaugh JL (1999) Norepinephrine infused into the basolateral amygdala posttraining enhances retention in a spatial water maze task. Neurobiol. Learn. Mem. 71, 232-239.
16. Huang Y, Yang S, Zhou WX, Zhang YX (2008) The method of long-term potentiation recording in hippocampus in anaesthetized mice in vivo. Zhongguo. Ying. Yong. Sheng. Li. Xue. Za. Zhi. 24, 291-295.
17. Huang ZS, Li Y, Huang J, Li SB, Nong S (2010) Effects of TSG on cholinergic neurotransmitter and monoamine neurotransmitter in SAMP8 mice’s brain. Youjiang Med. 38, 381-383.
18. Igor P, Pogribny, Boris F Vanyushin (2010) Age-related genomic hypomethylation. Epigenetics of Aging, 11-27.
19. Izumi Y, Zorumski CF (1999) Norepinephrine promotes long-term potentiation in the adult rat hippocampus in vitro. Synapse 31, 196-202.
20. Jonsson G (1969) Microfluorimetric studies on the formaldehyde-induced fluorescence of noradrenaline in adrenergic nerves of rat iris. J. Histochem. Cytochem. 17, 714-723.
21. Karuppagounder SS, Pinto JT, Xu H, Chen HL, Beal MF, Gibson GE (2009) Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer’s disease. Neurochem. Int. 54, 111-118.
22. Lapiz MD, Mateo Y, Durkin S, Parker T, Marsden CA (2001) Effects of central noradrenaline depletion by the selective neurotoxin DSP-4 on the behaviour of the isolated rat in the elevated plus maze and water maze. Psychopharmacology 155, 251-259.
23. Liu L, van Groen T, Kadish I, Tollefsbol TO (2009) DNA methylation impacts on learning and memory in aging. Neurobiol. Aging 30, 549-560.
24. Lopatina N, Haskell JF, Andrews LG, Poole JC, Saldanha S, Tollefsbol T (2002) Differential maintenance and de novo methylating activity by three DNA methyltransferases in aging and immortalized fibroblasts. J. Cell. Biochem. 84, 324-334.
25. Luine V, Bowling D, Hearns M (1990) Spatial memory deficits in aged rats: contributions of monoaminergic systems. Brain Res. 537, 271-278.
26. Luo W, Li H, Zhang Y, Ang CY (2001) Determination of formaldehyde in blood plasma by high-performance liquid chromatography with fluorescence detection. J. Chromatogr. B Biomed. Sci. Appl. 753, 253-257.
27. Mastroeni D, Grover A, Delvaux E, Whiteside C, Coleman PD, Rogers J (2011) Epigenetic mechanisms in Alzheimer’s disease. Neurobiol. Aging 32, 1161-1180.
28. Miller CA, Gavin CF, White JA, Parrish RR, Honasoge A, Yancey CR, Rivera IM, Rubio MD, Rumbaugh G, Sweatt JD (2010) Cortical DNA methylation maintains remote memory. Nat. Neurosci. 13, 664-666.
29. Morris R (1984) Developments of a water-maze procedure for studying spatial learning in the rat. J. Neurosci. Methods 11, 47-60.
30. Oliveira AM, Hemstedt TJ, Bading H (2012) Rescue of aging-associated decline in Dnmt3a2 expression restores cognitive abilities. Nat. Neurosci. 15, 1111-1113.
31. Patra SK, Patra A, Rizzi F, Ghosh TC, Bettuzzi S (2008) Demethylation of (Cytosine-5-C-methyl) DNA and regulation of transcription in the epigenetic pathways of cancer development. Cancer Metastasis Rev. 27, 315-334.
32. Peskind ER, Wingerson D, Murray S, Pascualy M, Dobie DJ, Le Corre P, Le Verge R, Veith RC, Raskind MA (1995) Effects of Alzheimer’s disease and normal aging on cerebrospinal fluid norepinephrine responses to yohimbine and clonidine. Arch. Gen. Psychiatry 52, 774-782.
33. Stanton PK, Sarvey JM (1985) Depletion of norepinephrine, but not serotonin, reduces long-term potentiation in the dentate gyrus of rat hippocampal slices. J. Neurosci. 5, 2169-2176.
34. Szot P, Leverenz JB, Peskind ER, Kiyasu E, Rohde K, Miller MA, Raskind MA (2000) Tyrosine hydroxylase and norepinephrine transporter mRNA expression in the locus coeruleus in Alzheimer’s disease. Brain Res. Mol. Brain Res. 84, 135-140.
35. Tan T, Xie J, Tong Z, Liu T, Chen X, Tian X (2013) Repetitive transcranial magnetic stimulation increases excitability of hippocampal CA1 pyramidal neurons. Brain Res. 1520, 23-35.
36. Tani T (1981) Relaxation of vascular smooth muscle induced by formaldehyde (author’s transl). Nihon. Yakurigaku. Zasshi. 77, 221-230.
37. Tong ZQ, Luo WH, Wang YQ, Yang F, Hang Y, Li H, Luo HJ, Duan B, Xu TL, Maoying QL, Tan HY, Wang J, Zhao H, Liu FY, Wan Y. (2010) Tumor tissuederived formaldehyde and acidic microenvironment synergistically induce bone cancer pain. PLoS ONE 5, e10234.
38. Tong ZQ, Zhang J, Luo WH, Wang WS, Li FX, Li H, Luo HJ, Lu J, Zhou JL, Wan Y, He RQ (2011) Urine formaldehyde level is inversely correlated to mini mental state examination scores in senile dementia. Neurobiol. Aging 32, 31-42.
39. Tong Z, Han C, Luo W, Li H, Luo H, Qiang M, Su T, Wu B, Liu Y, Yang X, Wan Y, Cui D, He R (2013a) Aging-associated excess formaldehyde leads to spatial memory deficits. Sci. Rep. 3, 1807.
40. Tong Z, Han C, Luo W, Wang X, Li H, Luo H, Zhou J, Qi J, He R (2013b) Accumulated hippocampal formaldehyde induces age-dependent memory decline. Age (Dordr). 35, 583-596.
41. Tully K, Li Y, Tsvetkov E, Bolshakov VY (2007) Norepinephrine enables the induction of associative long-term potentiation at thalamo-amygdala synapses. Proc. Natl Acad. Sci. USA 104, 14146-14150.
42. Tulpule K, Dringen R (2012) Formate generated by cellular oxidation of formaldehyde accelerates the glycolytic flux in cultured astrocytes. Glia 60, 582-593.
43. Tyihak E, Albert L, Nemeth ZI, Katay G, Kiraly-Veghely Z, Szende B (1998) Formaldehyde cycle and the natural formaldehyde generators and capturers. Acta Biol. Hung. 49, 225-238.
44. Wu SC, Zhang Y (2010) Active DNA demethylation: many roads lead to Rome. Nat. Rev. Mol. Cell Biol. 11, 607-620.
45. Yamaguchi M, Ishida J, Yoshimura M (1998) Simultaneous determination of urinary catecholamines and 5-hydroxyindoleamines by high-performance liquid chromatography with fluorescence detection. Analyst 123, 307-311.