Fucosyltransferase IV (FUT4) as an effective biomarker for the diagnosis of breast cancer

Biomedicine and Pharmacotherapy

Volumn 70, Issue C, 2015, Pages 299-304

  Yan, Xiaomei ^a   Lin, Yingwei ^a   Liu, Shuai ^a   aziz, Faisal ^a   Yan, Qiu ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

Biomarker; CA15.3; CEA; FUT4

Indexed keywords

CA 15-3 ANTIGEN; CARCINOEMBRYONIC ANTIGEN; FUCOSYLTRANSFERASE; FUCOSYLTRANSFERASE 4; TUMOR MARKER; UNCLASSIFIED DRUG; CD15 ANTIGEN; FUT4 PROTEIN, HUMAN;

ARTICLE; BLOOD SAMPLING; BREAST CANCER; BREAST CANCER CELL LINE; CANCER DIAGNOSIS; CONTROLLED STUDY; ELECTROCHEMICAL ANALYSIS; ELECTROCHEMICAL IMMUNE ASSAY; ENZYME BLOOD LEVEL; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOASSAY ANALYZER; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; WESTERN BLOTTING; BIOSYNTHESIS; BLOOD; BREAST NEOPLASMS; FEMALE; MCF 7 CELL LINE; METABOLISM;

ANTIGENS, CD15; BIOMARKERS, TUMOR; BREAST NEOPLASMS; FEMALE; FUCOSYLTRANSFERASES; HUMANS; MCF-7 CELLS;

EID: 84927520503     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2014.12.048     Document Type: Article

References (34)

1. Chen W., Zheng R., Zhang S., Zhao P., Zeng H., Zou X. Report of cancer incidence and mortality in China, 2010. Ann Transl Med 2014, 2(7). 61-61.
2. Li J., Zhang Z., Rosenzweig J., Wang Y.Y., Chan D.W. Proteomics and bioinformatics approaches for identification of serum biomarkers to detect breast cancer. Clin Chem 2002, 48(8):1296-1304.
3. Molina R., Jo J., Filella X., Zanon G., Farrus B., Munoz M., et al. C-erbB-2 CEA and CA 15.3 serum levels in the early diagnosis of recurrence of breast cancer patients. Anticancer Res 1999, 19(4A):2551-2555.
4. Dede D.S., Arslan C., Altundag K. Serum levels of CEA and CA 15-3 in triple-negative breast cancer at the time of diagnosis. Med Oncol 2010, 27(4):1429.
5. Eskelinen M., Kataja V., Hamalainen E., Kosma V.M., Penttila I., Alhava E. Serum tumour markers CEA, AFP, CA 15-3 TPS and Neu in diagnosis of breast cancer. Anticancer Res 1997, 17(2B):1231-1234.
6. Eskelinen M., Hippelainen M., Kettunen J., Salmela E., Penttila I., Alhava E. Clinical value of serum tumour markers TPA, TPS, TAG 12 CA 15-3 and MCA in breast cancer diagnosis; results from a prospective study. Anticancer Res 1994, 14(2B):699-703.
7. Xie S., Ding X., Mo W., Chen J. Serum tissue polypeptide specific antigen is an independent predictor in breast cancer. Acta Histochem 2014, 116(2):372-376.
8. Wang XF1, Wu Y.H., Wang M.S. Wang YS. CEA, AFP, CA125 CA15.3 and CA199 in malignant pleural effusions predict the cause. Asian Pac J Cancer Prev 2014, 15(1):363-368.
9. Hashimoto T., Matsubara F. Changes in the tumor marker concentration in female patients with hyper-, eu-, and hypothyroidism. Endocrinol Jpn 1989, 36(6):873-879.
10. Molina R., Barak V., van Dalen A., Duffy M.J., Einarsson R., Gion M., et al. Tumor markers in breast cancer-European Group on Tumor Markers recommendations. Tumour Biol 2005, 26(6):281-293.
11. Park J.S., Rha S.Y., Chung H.C., Jung M., Kim K.H., Jun H.J., et al. Clinicopathological features and prognostic significance of HER2 expression in gastric cancer. Oncology 2014, 88(3):147-156.
12. Shinkel T.A., Chen C.G., Salvaris E., Henion T.R., Barlow H., Galili U., et al. Changes in cell surface glycosylation in alpha1,3-galactosyltransferase knockout and alpha1,2-fucosyltransferase transgenic mice. Transplantation 1997, 64(2):197-204.
13. Wright R.D., Cooper D. Glycobiology of leukocyte trafficking ininflammation. Glycobiology 2014, 24(12):1242-1251.
14. Goulabchand R., Vincent T., Batteux F., Eliaou J.F., Guilpain P. Impact of autoantibody glycosylation in autoimmune diseases. Autoimmun Rev 2014, 13(7):742-750.
15. Moriwaki K1, Miyoshi E. Fucosylation and gastrointestinal cancer. World J Hepatol 2010, 2(4):151-161.
16. Miyoshi E., Moriwaki K., Nakagawa T. Biological function of fucosylation in cancer biology. J Biochem 2008, 143(6):725-729.
17. Hakomori S. Glycosylation defining cancer malignancy: new wine in an old bottle. Proc Natl Acad Sci U S A 2002, 99(16):10231-10233.
18. Weston B.W., Nair R.P., Larsen R.D., Lowe J.B. Isolation of a novel human alpha(1,3)fucosyltransferase gene and molecular comparison to the human Lewis blood group alpha (1,3/1,4)fucosyltransferase gene. Syntenic, homologous, nonallelic genes encoding enzymes with distinct acceptor substrate specificities. J Biol Chem 1992, 267:4152-4160.
19. Weston B.W., Smith P.L., Kelly R.J., Lowe J.B. Molecular cloning of a fourth member of a human alpha (1,3)fucosyltransferase gene family multiple homologous sequences that determine expression of the Lewis x, sialyl Lewis x, and difucosyl sialyl Lewis x epitopes. J Biol Chem 1992, 267:24575-24584.
20. Sasaki K., Kurata K., Funayama K., Nagata M., Watanabe E., Ohta S., et al. Expression cloning of a novel alpha 1,3-fucosyltransferase that is involved in biosynthesis of the sialyl Lewis x carbohydrate determinants in leukocytes. J Biol Chem 1994, 269:14730-14737.
21. Taniguchi A., Suga R., Matsumoto K. Expression and transcriptional regulation of the human alpha1, 3-fucosyltransferase 4 (FUT4) gene in myeloid andcolon adenocarcinoma cell lines. Biochem Biophys Res Commun 2000, 273(1):370-376.
22. Breton C., Mucha J., Jeanneau C. Structural and functional features of glycosyltransferases. Biochimie 2001, 83(8):713-718.
23. Kudo T., Ikehara Y., Togayachi A., Kaneko M., Hiraga T., Sasaki K., et al. Expression cloning and characterization of a novel murine alpha 1,3-fucosyltransferase, mFuc-TIX, thatsynthesizes the Lewis x (CD15) epitope in brain and kidney. J Biol Chem 1998, 273(41):26729-26738.
24. Mas E., Pasqualini E., Caillol N., Battari E., Crotte A., Lombardo C., et al. Fucosyltransferase activities in human pancreatic tissue: comparative study between cancer tissues and established tumoral cell lines. Glycobiology 1998, 8(6):605-613.
25. Petretti T., Schulze B., Schlag P.M., Kemmner W. Altered mRNA expression of glycosyltransferases in human gastric carcinomas. Biochim Biophys Acta 1999, 1428(2-3):209-218.
26. Zhang Z., Sun P., Liu J., Fu L., Yan J., Liu Y., et al. Suppression of FUT1/FUT4 expression by siRNA inhibits tumor growth. Biochim Biophys Acta 2008, 1783(2):287-296.
27. Yang X., Zhangz, Jia S., Liu Y., Wang X., Yan Q. Overexpression of fucosyltransferase IV in A431 cell line increase cell proliferation. Int J Biochem Cell Biol 2007, 39(9):1722-1730.
28. Wei X., Liu S., Wang X., Yan Q. CD82 expression alters with human endometrial cycles and affects the uterine endometrial receptivity in vitro. Exp Biol Med 2012, 237(3):254-262.
29. Saitoh O., Wang W.C., Lotan R., Fukuda M. Differential glycosylation and cell surface expression of lysosomal membrane glycoproteins in sublines of a human colon cancer exhibiting distinctmetastaticpotentials. J Biol Chem 1992, 267(8):5700-5711.
30. Miyoshi E., Noda K., Yamaguchi Y., Inoue S., Ikeda Y., Wang W., et al. The alpha1-6-fucosyltransferase gene and its biological significance. Biochim Biophys Acta 1999, 1473(1):9-20.
31. Kessel D. Human serum fucosyltransferase and tumor therapy. Science 1979, 204(4393):647.
32. Bauer C.H., Reutter W.G., Erhart K.P., Köttgen E., Gerok W. Decrease of human serum fucosyltransferase as an indicator of successful tumor therapy. Science 1978, 201(4362):1232-1233.
33. Yang X., Liu S., Yan Q. Role of fucosyltransferase IV in epithelial-mesenchymal transition in breast cancer cells. Cell Death Dis 2013, 4:e735. 10.1038/cddis.2013.241.
34. Yang X., Wang J., Liu S., Yan Q. HSF1 and Sp1 regulate FUT4 gene expression and cell proliferation in breast cancer cells. J Cell Biochem 2014, 115(1):168-178.