Association of Single Nucleotide Polymorphisms in the IL27 Gene with Rheumatoid Arthritis

Scandinavian Journal of Immunology

Volumn 80, Issue 4, 2014, Pages 298-305

  Paradowska Gorycka, A ^a   Raszkiewicz, B ^a   Jurkowska, M ^a   Felis Giemza, A ^a   Romanowska Prochnicka, K ^a   Manczak M ^a   Olesinska, M ^a  

^a INSTITUTE OF RHEUMATOLOGY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 27; IL27 PROTEIN, HUMAN; INTERLEUKIN DERIVATIVE;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RHEUMATOID ARTHRITIS; SINGLE NUCLEOTIDE POLYMORPHISM; ADOLESCENT; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ARTHRITIS, RHEUMATOID; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; INTERLEUKINS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; YOUNG ADULT;

EID: 84927514368     PISSN: 03009475     EISSN: 13653083     Source Type: Journal    
DOI: 10.1111/sji.12209     Document Type: Article

References (28)

1. Kim HR, Cho ML, Kim KW et al. Up-regulation of IL-23p19 expression in rheumatoid arthritis synovial fibroblasts by IL-17 through PI3-kinase-, NF-kappaB- and p38 MAPK-dependent signalling pathways. Rheumatology (Oxford) 2007;46:57-64.
2. Paradowska A, Maslinski W, Grzybowska-Kowalczyk A, Lacki JK. The function of interleukin 17 in the pathogenesis of rheumatoid arthritis. Arch Immunol Ther Exp 2007;55:329-34.
3. Wong CK, Chen DP, Tam LS, Li EK, Yin YB, Lam CW. Effects of inflammatory cytokine IL-27 on the activation of fibroblast-like synoviocytes in rheumatoid arthritis. Arthritis Res Ther 2010;12:R129.
4. Bingham CO. The pathogenesis of rheumatoid arthritis: pivotal cytokines involved in bone degradation and inflammation. J Rheumatol 2002;29:3-9.
5. Rindlfeisch JA, Muller D. Diagnosis and management of rheumatoid arthritis. Am Fam Physician 2005;72:1037-47.
6. Newton JL, Harney SM, Timms AE et al. Dissection of class III major histocompatibility complex haplotypes associated with rheumatoid arthritis. Arthritis Rheum 2004;50:2122-9.
7. Bowes J, Barton A. Recent advances in the genetics of RA susceptibility. Rheumatology (Oxford) 2008;47:399-402.
8. Buch M, Emery P. The aethiology and pathogenesis of rheumatoid arthritis. Hospital Pharmacist 2002 pp. 9:5.
9. Reveille JD. Genetic studies in the rheumatic diseases: present status and implications for the future. J Rheumatol Suppl 2005;72:10-3.
10. van Roon JA, Lafeber FP, Bijlsma JW. Synergistic activity of interleukin-4 and interleukin-10 in suppression of inflammation and joint destruction in rheumatoid arthritis. Arthritis Rheum 2001;44:3-12.
11. MacKay K, Milicic A, Lee D et al. Rheumatoid arthritis susceptibility and interleukin 10: a study of two ethnically diverse populations. Rheumatology (Oxford) 2003;42:149-53.
12. Li CS, Zhang Q, Lee KJ et al. Interleukin-27 polymorphisms are associated with inflammatory bowel diseases in a Korean population. J Gastroenterol Hepatol 2009;24:1692-6.
13. Shen H, Xia L, Xiao W, Lu J. Increased levels of interleukin-27 in patients with rheumatoid arthritis. Arthritis Rheum 2011;63:860-1.
14. Pflanz SJ, Timans J, Cheung R et al. IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naïve CD4 + T cells. Immunity 2002;16:779-90.
15. Tanida S, Yoshitomi H, Ishikawa M et al. IL-27-producing CD14 + cells infiltrate inflamed joints of rheumatoid arthritis and regulate inflammation and chemotactic migration. Cytokine 2011;55:237-44.
16. Owaki T, Asakawa M, Morishima N et al. A role of IL-27 in early regulation of Th1 differentiation. J Immunol 2005;175:2191-200.
17. Cao Y, Doodes PD, Glant TT, Finnegan A. IL-27 induces a Th1 immune response and susceptibility to experimental arthritis. J Immunol 2008;180:922-30.
18. Jankowski M, Kopinski P, Goc A. Interleukin-27: biological properties and clinical application. Arch Immunol Ther Exp 2010;58:417-25.
19. Diveu C, McGeachy MJ, Boniface K et al. IL-27 blocks RORc expression to inhibit lineage commitment of Th1 cells. J Immunol 2009;182:5748-56.
20. Kamiya S, Okumura M, Chiba Y et al. IL-27 suppresses RANKL expression in CD4 + T cells in part through STAT3. Immunol Lett 2011;138:47-53.
21. Kalliolias GD, Zhao B, Triantafyllopoulou A, Park-Min KH, Ivashkiv LB. IL-27 inhibits human osteoclastogenesis by abrogating RANKL-mediated induction of NFATc1 and suppressing proximal RANK signaling. Arthritis Rheum 2010;62:402.
22. Chae SC, Li CS, Kim KM et al. Identification of polymorphisms in human interleukin-27 and their association with asthma in a Korean population. J Hum Genet 2007;52:355-61.
23. Huang N, Liu L, Wang XZ, Liu D, Yin SY, Yang XD. Association of interleukin (IL)-12 and IL-27 gene polymorphisms with chronic obstructive pulmonary disease in a Chinese population. DNA Cell Biol 2008;27:527-31.
24. Santos AS, Melo ME, Crisostomo LG, Fukui RT, Matioli SR, Silva ME. Lack of association between IL27 gene variants and type 1 diabetes susceptibility. Cytokine 2013;61:349-52.
25. Wei YS, Lan Y, Luo B, Lu D, Nong HB. Association of variants in the interleukin-27 and interleukin-12 gene with nasopharyngeal carcinoma. Mol Carcinog 2009;48:751-7.
26. Peng Q, Qin X, He Y et al. Association of IL27 gene polymorphisms and HBV-related hepatocellular carcinoma risk in a Chinese population. Infect Genet Evol 2013;16:1-4.
27. Huang ZQ, Wang JL, Pan GG, Wei YS. Association of single nucleotide polymorphisms in IL-12 and IL-27 genes with colorectal cancer risk. Clin Biochem 2012;45:54-9.
28. McAllister K, Eyre S, Orozco G. Genetics of rheumatoid arthritis: GWAS and beyond. Open Access Rheumatology: Research and Reviews 2011;3:31-46.