MiR-182 promotes cell growth and invasion by targeting forkhead box F2 transcription factor in colorectal cancer

Oncology Reports

Volumn 33, Issue 5, 2015, Pages 2592-2598

  Zhang, Yu ^a   Wang, Xinying ^b   Wang, Zhongqiu ^b   Tang, Hui ^a   Fan, Hong ^a   Guo, Qiang ^a  

^a The Second Hospital of Yunnan Province   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Cell invasion; Colorectal cancer; FoxF2; Microrna; MiR 182

Indexed keywords

BETA CATENIN; MESSENGER RNA; MICRORNA 182; 3' UNTRANSLATED REGION; FORKHEAD TRANSCRIPTION FACTOR; FOXF2 PROTEIN, HUMAN; MICRORNA; MIRN182 MICRORNA, HUMAN; TRANSCRIPTION FACTOR;

3' UNTRANSLATED REGION; ARTICLE; BIOINFORMATICS; CANCER TISSUE; CELL GROWTH; CELL INVASION; CELL PROLIFERATION; CELL SURVIVAL; COLON MUCOSA; COLORECTAL CANCER; COLORECTAL CANCER CELL LINE; CONTROLLED STUDY; DOWN REGULATION; FOXF2 GENE; GENE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HCT116 CELL LINE; HT 29 CELL LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LUCIFERASE ASSAY; MOLECULAR INTERACTION; PRIMARY TUMOR; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SW480 CELL LINE; SW620 CELL LINE; UPREGULATION; CELL LINE; COLORECTAL TUMOR; EPITHELIUM CELL; GENETICS; HEK293 CELL LINE; METABOLISM; PROCEDURES; TUMOR CELL LINE; TUMOR INVASION;

3' UNTRANSLATED REGIONS; BETA CATENIN; CELL LINE; CELL LINE, TUMOR; CELL PROLIFERATION; COLORECTAL NEOPLASMS; DOWN-REGULATION; EPITHELIAL CELLS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HCT116 CELLS; HEK293 CELLS; HT29 CELLS; HUMANS; MICRORNAS; NEOPLASM INVASIVENESS; RNA, MESSENGER; TRANSCRIPTION FACTORS; UP-REGULATION;

EID: 84927155260     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2015.3833     Document Type: Article

References (32)

1. Kaufmann E and Knochel W: Five years on the wings of fork head. Mech Dev 57:3-20, 1996.
2. Dong XY, Chen C, Sun X, Guo P, Vessella RL, Wang RX, Chung LW, Zhou W and Dong JT: FOXO1A is a candidate for the 13q14 tumor suppressor gene inhibiting androgen receptor signaling in prostate cancer. Cancer Res 66:6998-7006, 2006.
3. Zhang H, Meng F, Liu G, Zhang B, Zhu J, Wu F, Ethier SP, Miller F and Wu G: Forkhead transcription factor Foxq1 promotes epithelial-mesenchymal transition and breast cancer metastasis. Cancer Res 71:1292-1301, 2011.
4. Qiao Y, Jiang X, Lee ST, Karuturi RK, Hooi SC and Yu Q: FOXQ1 regulates epithelial-mesenchymal transition in human cancers. Cancer Res 71:3076-3086, 2011.
5. Van Der Heul-Nieuwenhuijsen L, Dits N, Van Ijcken W, De Lange D and Jenster G: The FOXF2 pathway in the human prostate stroma. Prostate 69:1538-1547, 2009.
6. Kong PZ, Yang F, Li L, Li XQ and Feng YM: Decreased FOXF2 mRNA expression indicates early-onset metastasis and poor prognosis for breast cancer patients with histological grade II tumor. PLoS One 8:e61591, 2013.
7. Ormestad M, Astorga J, Landgren H, Wang T, Johansson BR, Miura N and Carlsson P: Foxf1 and Foxf2 control murine gut development by limiting mesenchymal Wnt signaling and promoting extracellular matrix production. Development 133:833-843, 2006.
8. + stem cells and adenoma formation by inhibiting Wnt signaling. Gastroenterology 144:1001-1011, 2013.
9. Guttilla IK and White BA: Coordinate regulation of FOXO1 by miR-27a, miR-96, and miR-182 in breast cancer cells. J Biol Chem 284:23204-23216, 2009.
10. Chiang CH, Hou MF and Hung WC: Up-regulation of miR-182 by β-catenin in breast cancer increases tumorigenicity and invasiveness by targeting the matrix metalloproteinase inhibitor RECK. Biochim Biophys Acta 1830:3067-3076, 2013.
11. Liu Z, Liu J, Segura MF, Shao C, Lee P, Gong Y, Hernando E and Wei JJ: MiR-182 overexpression in tumourigenesis of high-grade serous ovarian carcinoma. J Pathol 228:204-215, 2012.
12. Tsuchiyama K, Ito H, Taga M, Naganuma S, Oshinoya Y, Nagano K, Yokoyama O and Itoh H: Expression of microRNAs associated with Gleason grading system in prostate cancer: miR-182-5p is a useful marker for high grade prostate cancer. Prostate 73:827-834, 2013.
13. Segura MF, Hanniford D, Menendez S, et al: Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor. Proc Natl Acad Sci USA 106:1814-1819, 2009.
14. Lei R, Tang J, Zhuang X, Deng R, Li G, Yu J, Liang Y, Xiao J, Wang HY, Yang Q and Hu G: Suppression of MIM by microRNA-182 activates RhoA and promotes breast cancer metastasis. Oncogene 33:1287-1296, 2014.
15. Moskwa P, Buffa FM, Pan Y, et al: miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors. Mol Cell 41:210-220, 2011.
16. Zhang QH, Sun HM, Zheng RZ, Li YC, Zhang Q, Cheng P, Tang ZH and Huang F: Meta-analysis of microRNA-183 family expression in human cancer studies comparing cancer tissues with noncancerous tissues. Gene 527:26-32, 2013.
17. Cekaite L, Rantala JK, Bruun J, et al: MiR-9, -31, and -182 deregulation promote proliferation and tumor cell survival in colon cancer. Neoplasia 14:868-879, 2012.
18. Sabates-Bellver J, Van Der Flier LG, De Palo M, et al: Transcriptome profile of human colorectal adenomas. Mol Cancer Res 5:1263-1275, 2007.
19. Jiang X, Tan J, Li J, et al: DACT3 is an epigenetic regulator of Wnt/β-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications. Cancer Cell 13:529-541, 2008.
20. Jorissen RN, Lipton L, Gibbs P, et al: DNA copy-number alterations underlie gene expression differences between microsatellite stable and unstable colorectal cancers. Clin Cancer Res 14:8061-8069, 2008.
21. Smith JJ, Deane NG, Wu F, et al: Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer. Gastroenterology 138:958-968, 2010.
22. Watanabe T, Kobunai T, Toda E, et al: Distal colorectal cancers with microsatellite instability (MSI) display distinct gene expression profiles that are different from proximal MSI cancers. Cancer Res 66:9804-9808, 2006.
23. Tsukamoto S, Ishikawa T, Iida S, Ishiguro M, Mogushi K, Mizushima H, Uetake H, Tanaka H, Sugihara K: Clinical significance of osteoprotegerin expression in human colorectal cancer. Clin Cancer Res 17:2444-2450, 2011.
24. Hirata H, Ueno K, Shahryari V, Deng G, Tanaka Y, Tabatabai ZL, Hinoda Y and Dahiya R: MicroRNA-182-5p promotes cell invasion and proliferation by down regulating FOXF2, RECK and MTSS1 genes in human prostate cancer. PLoS One 8:e55502, 2013.
25. Jiang L, Mao P, Song L, Wu J, Huang J, Lin C, Yuan J, Qu L, Cheng SY and Li J: miR-182 as a prognostic marker for glioma progression and patient survival. Am J Pathol 177:29-38, 2010.
26. Sun Y, Fang R, Li C, Li L, Li F, Ye X and Chen H: Hsa-mir-182 suppresses lung tumorigenesis through down regulation of RGS17 expression in vitro. Biochem Biophys Res Commun 396:501-507, 2010.
27. Sarver AL, French AJ, Borralho PM, et al: Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states. BMC Cancer 9:401, 2009.
28. Liu H, Du L, Wen Z, et al: Up-regulation of miR-182 expression in colorectal cancer tissues and its prognostic value. Int J Colorectal Dis 28:697-703, 2013.
29. Diep CB, Kleivi K, Ribeiro FR, Teixeira MR, Lindgjaerde OC and Lothe RA: The order of genetic events associated with colorectal cancer progression inferred from meta-analysis of copy number changes. Genes Chromosomes Cancer 45:31-41, 2006.
30. Wang T, Tamakoshi T, Uezato T, Shu F, Kanzaki-Kato N, Fu Y, Koseki H, Yoshida N, Sugiyama T and Miura N: Forkhead transcription factor Foxf2 (LUN)-deficient mice exhibit abnormal development of secondary palate. Dev Biol 259:83-94, 2003.
31. Aitola M, Carlsson P, Mahlapuu M, Enerback S and Pelto-Huikko M: Forkhead transcription factor FoxF2 is expressed in mesodermal tissues involved in epithelio-mesenchymal interactions. Dev Dyn 218:136-149, 2000.
32. Hirata H, Ueno K, Shahryari V, Tanaka Y, Tabatabai ZL, Hinoda Y and Dahiya R: Oncogenic miRNA-182-5p targets Smad4 and RECK in human bladder cancer. PLoS One 7:e51056, 2012.