Cytokeratin 5/6 fingerprinting in HER2-positive tumors identifies a poor prognosis and trastuzumab-resistant Basal-HER2 subtype of breast cancer

Oncotarget

Volumn 6, Issue 9, 2015, Pages 7104-7122

  Martin Castillo, Begoña ^a,b   Lopez Bonet, Eugeni ^b,c   Buxó, Maria ^b,d,e   Dorca, Joan ^a   Tuca Rodríguez, Francesc ^c   Ruano, Miguel Alonso ^c   Colomer, Ramon ^f,g   Menendez, Javier A ^a,b  

^a CATALAN INSTITUTE OF ONCOLOGY   (Spain)

^b GIRONA BIOMEDICAL RESEARCH INSTITUTE IDIBGI   (Spain)

^c HOSPITAL JOSEP TRUETA   (Spain)

^d Regional Government of Catalonia   (Spain)

^e UNIVERSITY OF GIRONA   (Spain)

^f Centro Nacional de Investigaciones Oncológicas   (Spain)

^g HOSPITAL UNIVERSITARIO DE LA PRINCESA   (Spain)

Author keywords

Basal like; Breast cancer; Cytokeratins; HER2; Trastuzumab

Indexed keywords

CYTOKERATIN 5; CYTOKERATIN 6; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; TRASTUZUMAB; ERBB2 PROTEIN, HUMAN; KRT5 PROTEIN, HUMAN;

ACCURACY; ADULT; ARTICLE; BREAST CARCINOMA; CANCER ADJUVANT THERAPY; CANCER CLASSIFICATION; CANCER GRADING; CANCER HORMONE THERAPY; CANCER PROGNOSIS; CANCER RECURRENCE; CANCER RESISTANCE; CANCER SURVIVAL; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE FREE SURVIVAL; DISTANT METASTASIS; DISTANT METASTASIS FREE SURVIVAL; DNA FINGERPRINTING; FEMALE; GENERAL ASPECTS OF DISEASE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MIDDLE AGED; OVERALL SURVIVAL; PREDICTIVE VALUE; PROTEIN EXPRESSION; RECURRENCE FREE SURVIVAL; REFERENCE VALUE; RETROSPECTIVE STUDY; SURVIVAL RATE; SURVIVAL TIME; TIME TO TREATMENT FAILURE; TREATMENT PLANNING; TUMOR VOLUME; AGED; ALGORITHM; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CHEMISTRY; DRUG RESISTANCE; KAPLAN MEIER METHOD; METABOLISM; PHENOTYPE; PROGNOSIS; PROSPECTIVE STUDY; TREATMENT OUTCOME;

ADULT; AGED; ALGORITHMS; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; DISEASE-FREE SURVIVAL; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; IMMUNOPHENOTYPING; KAPLAN-MEIER ESTIMATE; KERATIN-5; KERATIN-6; MIDDLE AGED; PHENOTYPE; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROSPECTIVE STUDIES; RECEPTOR, ERBB-2; RETROSPECTIVE STUDIES; TRASTUZUMAB; TREATMENT OUTCOME;

EID: 84927144393     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3106     Document Type: Article

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