-
1
-
-
0036225281
-
Reaching a genetic and molecular understanding of skeletal development
-
Karsenty, G., and Wagner, E. F. (2002) Reaching a genetic and molecular understanding of skeletal development. Dev. Cell 2, 389-406
-
(2002)
Dev. Cell
, vol.2
, pp. 389-406
-
-
Karsenty, G.1
Wagner, E.F.2
-
2
-
-
18744366041
-
Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts
-
Takayanagi, H., Kim, S., Koga, T., Nishina, H., Isshiki, M., Yoshida, H., Saiura, A., Isobe, M., Yokochi, T., Inoue, J., Wagner, E. F., Mak, T. W., Kodama, T., and Taniguchi, T. (2002) Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts. Dev. Cell 3, 889-901
-
(2002)
Dev. Cell
, vol.3
, pp. 889-901
-
-
Takayanagi, H.1
Kim, S.2
Koga, T.3
Nishina, H.4
Isshiki, M.5
Yoshida, H.6
Saiura, A.7
Isobe, M.8
Yokochi, T.9
Inoue, J.10
Wagner, E.F.11
Mak, T.W.12
Kodama, T.13
Taniguchi, T.14
-
3
-
-
2942731511
-
Nuclear factor of activated T-cells (NFAT) rescues osteoclastogenesis in precursors lacking c-Fos
-
Matsuo, K., Galson, D. L., Zhao, C., Peng, L., Laplace, C., Wang, K. Z., Bachler, M. A., Amano, H., Aburatani, H., Ishikawa, H., and Wagner, E. F. (2004) Nuclear factor of activated T-cells (NFAT) rescues osteoclastogenesis in precursors lacking c-Fos. J. Biol. Chem. 279, 26475-26480
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 26475-26480
-
-
Matsuo, K.1
Galson, D.L.2
Zhao, C.3
Peng, L.4
Laplace, C.5
Wang, K.Z.6
Bachler, M.A.7
Amano, H.8
Aburatani, H.9
Ishikawa, H.10
Wagner, E.F.11
-
4
-
-
0037460069
-
Jun dimerization protein 2 (JDP2), a member of the AP-1 family of transcription factor, mediates osteoclast differentiation induced by RANKL
-
Kawaida, R., Ohtsuka, T., Okutsu, J., Takahashi, T., Kadono, Y., Oda, H., Hikita, A., Nakamura, K., Tanaka, S., and Furukawa, H. (2003) Jun dimerization protein 2 (JDP2), a member of the AP-1 family of transcription factor, mediates osteoclast differentiation induced by RANKL. J. Exp. Med. 197, 1029-1035
-
(2003)
J. Exp. Med.
, vol.197
, pp. 1029-1035
-
-
Kawaida, R.1
Ohtsuka, T.2
Okutsu, J.3
Takahashi, T.4
Kadono, Y.5
Oda, H.6
Hikita, A.7
Nakamura, K.8
Tanaka, S.9
Furukawa, H.10
-
5
-
-
84870909437
-
The transcription factor Jdp2 controls bone homeostasis and antibacterial immunity by regulating osteoclast and neutrophil differentiation
-
Maruyama, K., Fukasaka, M., Vandenbon, A., Saitoh, T., Kawasaki, T., Kondo, T., Yokoyama, K. K., Kidoya, H., Takakura, N., Standley, D., Takeuchi, O., and Akira, S. (2012) The transcription factor Jdp2 controls bone homeostasis and antibacterial immunity by regulating osteoclast and neutrophil differentiation. Immunity 37, 1024-1036
-
(2012)
Immunity
, vol.37
, pp. 1024-1036
-
-
Maruyama, K.1
Fukasaka, M.2
Vandenbon, A.3
Saitoh, T.4
Kawasaki, T.5
Kondo, T.6
Yokoyama, K.K.7
Kidoya, H.8
Takakura, N.9
Standley, D.10
Takeuchi, O.11
Akira, S.12
-
6
-
-
0028173214
-
c-Fos: A key regulator of osteoclastmacrophage lineage determination and bone remodeling
-
Grigoriadis, A. E., Wang, Z. Q., Cecchini, M. G., Hofstetter, W., Felix, R., Fleisch, H. A., and Wagner, E. F. (1994) c-Fos: a key regulator of osteoclastmacrophage lineage determination and bone remodeling. Science 266, 443-448
-
(1994)
Science
, vol.266
, pp. 443-448
-
-
Grigoriadis, A.E.1
Wang, Z.Q.2
Cecchini, M.G.3
Hofstetter, W.4
Felix, R.5
Fleisch, H.A.6
Wagner, E.F.7
-
7
-
-
15444357762
-
Requirement for NF-κB in osteoclast and B-cell development
-
Franzoso, G., Carlson, L., Xing, L., Poljak, L., Shores, E. W., Brown, K. D., Leonardi, A., Tran, T., Boyce, B. F., and Siebenlist, U. (1997) Requirement for NF-κB in osteoclast and B-cell development. Genes Dev. 11, 3482-3496
-
(1997)
Genes Dev
, vol.11
, pp. 3482-3496
-
-
Franzoso, G.1
Carlson, L.2
Xing, L.3
Poljak, L.4
Shores, E.W.5
Brown, K.D.6
Leonardi, A.7
Tran, T.8
Boyce, B.F.9
Siebenlist, U.10
-
8
-
-
0141893375
-
M-CSF, TNFα and RANK ligand promote osteoclast survival by signaling through mTOR/S6 kinase
-
Glantschnig, H., Fisher, J. E., Wesolowski, G., Rodan, G. A., and Reszka, A. A. (2003) M-CSF, TNFα and RANK ligand promote osteoclast survival by signaling through mTOR/S6 kinase. Cell Death Differ. 10, 1165-1177
-
(2003)
Cell Death Differ
, vol.10
, pp. 1165-1177
-
-
Glantschnig, H.1
Fisher, J.E.2
Wesolowski, G.3
Rodan, G.A.4
Reszka, A.A.5
-
9
-
-
81155126111
-
Osteopontin signals through calcium and nuclear factor of activated T cells (NFAT) in osteoclasts: A novel RGD-dependent pathway promoting cell survival
-
Tanabe, N., Wheal, B. D., Kwon, J., Chen, H. H., Shugg, R. P., Sims, S. M., Goldberg, H. A., and Dixon, S. J. (2011) Osteopontin signals through calcium and nuclear factor of activated T cells (NFAT) in osteoclasts: a novel RGD-dependent pathway promoting cell survival. J. Biol. Chem. 286, 39871-39881
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 39871-39881
-
-
Tanabe, N.1
Wheal, B.D.2
Kwon, J.3
Chen, H.H.4
Shugg, R.P.5
Sims, S.M.6
Goldberg, H.A.7
Dixon, S.J.8
-
10
-
-
0035965998
-
Tumor necrosis factor-α supports the survival of osteoclasts through the activation of Akt and ERK
-
Lee, S. E., Chung, W. J., Kwak, H. B., Chung, C. H., Kwack, K. B., Lee, Z. H., and Kim, H. H. (2001) Tumor necrosis factor-α supports the survival of osteoclasts through the activation of Akt and ERK. J. Biol. Chem. 276, 49343-49349
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 49343-49349
-
-
Lee, S.E.1
Chung, W.J.2
Kwak, H.B.3
Chung, C.H.4
Kwack, K.B.5
Lee, Z.H.6
Kim, H.H.7
-
11
-
-
0035862994
-
Genetic evidence for a role for Src family kinases in TNF family receptor signaling and cell survival
-
Xing, L., Venegas, A. M., Chen, A., Garrett-Beal, L., Boyce, B. F., Varmus, H. E., and Schwartzberg, P. L. (2001) Genetic evidence for a role for Src family kinases in TNF family receptor signaling and cell survival. Genes Dev. 15, 241-253
-
(2001)
Genes Dev
, vol.15
, pp. 241-253
-
-
Xing, L.1
Venegas, A.M.2
Chen, A.3
Garrett-Beal, L.4
Boyce, B.F.5
Varmus, H.E.6
Schwartzberg, P.L.7
-
12
-
-
55749096409
-
Inhibition of Hsp90 activates osteoclast c-Src signaling and promotes growth of prostate carcinoma cells in bone
-
Yano, A., Tsutsumi, S., Soga, S., Lee, M. J., Trepel, J., Osada, H., and Neckers, L. (2008) Inhibition of Hsp90 activates osteoclast c-Src signaling and promotes growth of prostate carcinoma cells in bone. Proc. Natl. Acad. Sci. U.S.A. 105, 15541-15546
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 15541-15546
-
-
Yano, A.1
Tsutsumi, S.2
Soga, S.3
Lee, M.J.4
Trepel, J.5
Osada, H.6
Neckers, L.7
-
13
-
-
0042527167
-
Cdc37 goes beyond Hsp90 and kinases
-
MacLean, M., and Picard, D. (2003) Cdc37 goes beyond Hsp90 and kinases. Cell Stress Chaperones 8, 114-119
-
(2003)
Cell Stress Chaperones
, vol.8
, pp. 114-119
-
-
MacLean, M.1
Picard, D.2
-
14
-
-
77950343791
-
Pattern recognition receptors and inflammation
-
Takeuchi, O., and Akira, S. (2010) Pattern recognition receptors and inflammation. Cell 140, 805-820
-
(2010)
Cell
, vol.140
, pp. 805-820
-
-
Takeuchi, O.1
Akira, S.2
-
15
-
-
0037129205
-
RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-β
-
Takayanagi, H., Kim, S., Matsuo, K., Suzuki, H., Suzuki, T., Sato, K., Yokochi, T., Oda, H., Nakamura, K., Ida, N., Wagner, E. F., and Taniguchi, T. (2002) RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-β. Nature 416, 744-749
-
(2002)
Nature
, vol.416
, pp. 744-749
-
-
Takayanagi, H.1
Kim, S.2
Matsuo, K.3
Suzuki, H.4
Suzuki, T.5
Sato, K.6
Yokochi, T.7
Oda, H.8
Nakamura, K.9
Ida, N.10
Wagner, E.F.11
Taniguchi, T.12
-
16
-
-
69049086481
-
TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis
-
Kawagoe, T., Takeuchi, O., Takabatake, Y., Kato, H., Isaka, Y., Tsujimura, T., and Akira, S. (2009) TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis. Nat. Immunol. 10, 965-972
-
(2009)
Nat. Immunol.
, vol.10
, pp. 965-972
-
-
Kawagoe, T.1
Takeuchi, O.2
Takabatake, Y.3
Kato, H.4
Isaka, Y.5
Tsujimura, T.6
Akira, S.7
-
17
-
-
84865268664
-
TRAF family member-associated NF-κB activator (TANK) is a negative regulator of osteoclastogenesis and bone formation
-
Maruyama, K., Kawagoe, T., Kondo, T., Akira, S., and Takeuchi, O. (2012) TRAF family member-associated NF-κB activator (TANK) is a negative regulator of osteoclastogenesis and bone formation. J. Biol. Chem. 287, 29114-29124
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 29114-29124
-
-
Maruyama, K.1
Kawagoe, T.2
Kondo, T.3
Akira, S.4
Takeuchi, O.5
-
18
-
-
84878035924
-
Critical role of AZI2 in GM-CSF-induced dendritic cell differentiation
-
Fukasaka, M., Ori, D., Kawagoe, T., Uematsu, S., Maruyama, K., Okazaki, T., Kozaki, T., Imamura, T., Tartey, S., Mino, T., Satoh, T., Akira, S., and Takeuchi, O. (2013) Critical role of AZI2 in GM-CSF-induced dendritic cell differentiation. J. Immunol. 190, 5702-5711
-
(2013)
J. Immunol.
, vol.190
, pp. 5702-5711
-
-
Fukasaka, M.1
Ori, D.2
Kawagoe, T.3
Uematsu, S.4
Maruyama, K.5
Okazaki, T.6
Kozaki, T.7
Imamura, T.8
Tartey, S.9
Mino, T.10
Satoh, T.11
Akira, S.12
Takeuchi, O.13
-
19
-
-
0026481133
-
Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor
-
Inaba, K., Inaba, M., Romani, N., Aya, H., Deguchi, M., Ikehara, S., Muramatsu, S., and Steinman, R. M. (1992) Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 176, 1693-1702
-
(1992)
J. Exp. Med.
, vol.176
, pp. 1693-1702
-
-
Inaba, K.1
Inaba, M.2
Romani, N.3
Aya, H.4
Deguchi, M.5
Ikehara, S.6
Muramatsu, S.7
Steinman, R.M.8
-
20
-
-
0347517833
-
Pulmonary alveolar proteinosis
-
Trapnell, B. C., Whitsett, J. A., and Nakata, K. (2003) Pulmonary alveolar proteinosis. N. Engl. J. Med. 349, 2527-2539
-
(2003)
N. Engl. J. Med.
, vol.349
, pp. 2527-2539
-
-
Trapnell, B.C.1
Whitsett, J.A.2
Nakata, K.3
-
21
-
-
0028236526
-
Granulocyte/ macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology
-
Stanley, E., Lieschke, G. J., Grail, D., Metcalf, D., Hodgson, G., Gall, J. A., Maher, D. W., Cebon, J., Sinickas, V., and Dunn, A. R. (1994) Granulocyte/ macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology. Proc. Natl. Acad. Sci. U.S.A. 91, 5592-5596
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 5592-5596
-
-
Stanley, E.1
Lieschke, G.J.2
Grail, D.3
Metcalf, D.4
Hodgson, G.5
Gall, J.A.6
Maher, D.W.7
Cebon, J.8
Sinickas, V.9
Dunn, A.R.10
-
22
-
-
37249039971
-
ABCG1 is deficient in alveolar macrophages of GM-CSF knockout mice and patients with pulmonary alveolar proteinosis
-
Thomassen, M. J., Barna, B. P, Malur, A. G., Bonfield, T. L., Farver, C. F, Malur, A., Dalrymple, H., Kavuru, M. S., and Febbraio, M. (2007) ABCG1 is deficient in alveolar macrophages of GM-CSF knockout mice and patients with pulmonary alveolar proteinosis. J. Lipid Res. 48, 2762-2768
-
(2007)
J. Lipid Res.
, vol.48
, pp. 2762-2768
-
-
Thomassen, M.J.1
Barna, B.P.2
Malur, A.G.3
Bonfield, T.L.4
Farver, C.F.5
Malur, A.6
Dalrymple, H.7
Kavuru, M.S.8
Febbraio, M.9
-
23
-
-
0001105230
-
Pulmonary alveolar proteinosis
-
Rosen, S. H., Castleman, B., and Liebow, A. A. (1958) Pulmonary alveolar proteinosis. N. Engl. J. Med. 258, 1123-1142
-
(1958)
N. Engl. J. Med.
, vol.258
, pp. 1123-1142
-
-
Rosen, S.H.1
Castleman, B.2
Liebow, A.A.3
-
24
-
-
33751521013
-
Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction
-
Sato, K., Suematsu, A., Okamoto, K., Yamaguchi, A., Morishita, Y., Kadono, Y., Tanaka, S., Kodama, T., Akira, S., Iwakura, Y., Cua, D. J., and Takayanagi, H. (2006) Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction. J. Exp. Med. 203, 2673-2682
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2673-2682
-
-
Sato, K.1
Suematsu, A.2
Okamoto, K.3
Yamaguchi, A.4
Morishita, Y.5
Kadono, Y.6
Tanaka, S.7
Kodama, T.8
Akira, S.9
Iwakura, Y.10
Cua, D.J.11
Takayanagi, H.12
-
25
-
-
67651142330
-
The proinflammatory cytokines IL-1β and TNF-α induce the expression of Synoviolin, an E3 ubiquitin ligase, in mouse synovial fibroblasts via the Erk1/2-ETS1 pathway
-
Gao, B., Calhoun, K., and Fang, D. (2006) The proinflammatory cytokines IL-1β and TNF-α induce the expression of Synoviolin, an E3 ubiquitin ligase, in mouse synovial fibroblasts via the Erk1/2-ETS1 pathway. Arthritis Res. Ther. 8, R172
-
(2006)
Arthritis Res. Ther.
, vol.8
, pp. R172
-
-
Gao, B.1
Calhoun, K.2
Fang, D.3
-
26
-
-
33746528704
-
Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis
-
Zhao, C., Irie, N., Takada, Y., Shimoda, K., Miyamoto, T., Nishiwaki, T., Suda, T., and Matsuo, K. (2006) Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis. Cell Metab. 4, 111-121
-
(2006)
Cell Metab
, vol.4
, pp. 111-121
-
-
Zhao, C.1
Irie, N.2
Takada, Y.3
Shimoda, K.4
Miyamoto, T.5
Nishiwaki, T.6
Suda, T.7
Matsuo, K.8
-
27
-
-
33748513678
-
Receptor activator of NF-κB ligand and osteoprotegerin regulate proinflammatory cytokine production in mice
-
Maruyama, K., Takada, Y., Ray, N., Kishimoto, Y., Penninger, J. M., Yasuda, H., and Matsuo, K. (2006) Receptor activator of NF-κB ligand and osteoprotegerin regulate proinflammatory cytokine production in mice. J. Immunol. 177, 3799-3805
-
(2006)
J. Immunol.
, vol.177
, pp. 3799-3805
-
-
Maruyama, K.1
Takada, Y.2
Ray, N.3
Kishimoto, Y.4
Penninger, J.M.5
Yasuda, H.6
Matsuo, K.7
-
28
-
-
77749320194
-
A protocol for isolation and culture of mesenchymal stem cells from mouse compact bone
-
Zhu, H., Guo, Z. K., Jiang, X. X., Li, H., Wang, X. Y., Yao, H. Y., Zhang, Y., and Mao, N. (2010) A protocol for isolation and culture of mesenchymal stem cells from mouse compact bone. Nat. Protoc. 5, 550-560
-
(2010)
Nat. Protoc.
, vol.5
, pp. 550-560
-
-
Zhu, H.1
Guo, Z.K.2
Jiang, X.X.3
Li, H.4
Wang, X.Y.5
Yao, H.Y.6
Zhang, Y.7
Mao, N.8
-
30
-
-
77956954197
-
The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection
-
Satoh, T., Takeuchi, O., Vandenbon, A., Yasuda, K., Tanaka, Y., Kumagai, Y., Miyake, T., Matsushita, K., Okazaki, T., Saitoh, T., Honma, K., Matsuyama, T., Yui, K., Tsujimura, T., Standley, D. M., Nakanishi, K., Nakai, K., and Akira, S. (2010) The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection. Nat. Immunol. 11, 936-944
-
(2010)
Nat. Immunol.
, vol.11
, pp. 936-944
-
-
Satoh, T.1
Takeuchi, O.2
Vandenbon, A.3
Yasuda, K.4
Tanaka, Y.5
Kumagai, Y.6
Miyake, T.7
Matsushita, K.8
Okazaki, T.9
Saitoh, T.10
Honma, K.11
Matsuyama, T.12
Yui, K.13
Tsujimura, T.14
Standley, D.M.15
Nakanishi, K.16
Nakai, K.17
Akira, S.18
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