The clinical relevance of the miR-197/CKS1B/STAT3-mediated PD-L1 network in chemoresistant non-small-cell lung cancer

Molecular Therapy

Volumn 23, Issue 4, 2015, Pages 717-727

  Fujita, Yu ^a,b   Yagishita, Shigehiro ^c   Hagiwara, Keitaro ^a   Yoshioka, Yusuke ^a   Kosaka, Nobuyoshi ^a   Takeshita, Fumitaka ^a   Fujiwara, Tomohiro ^a   Tsuta, Koji ^c   Nokihara, Hiroshi ^c   Tamura, Tomohide ^c   Asamura, Hisao ^c   Kawaishi, Makoto ^b   Kuwano, Kazuyoshi ^b   Ochiya, Takahiro ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c NATIONAL CANCER CENTER HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC METAL COMPLEX; CDC28 PROTEIN KINASE REGULATORY SUBUNIT 1B; CISPLATIN; CYCLIN D1; CYCLIN DEPENDENT KINASE; MESSENGER RNA; MICRORNA; MICRORNA 1260; MICRORNA 181C; MICRORNA 197; MICRORNA 21; MICRORNA 210; MYC PROTEIN; PACLITAXEL; PROGRAMMED DEATH 1 LIGAND 1; PROTEIN BCL 2; SMALL INTERFERING RNA; STAT3 PROTEIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CD274 PROTEIN, HUMAN; CKS1B PROTEIN, HUMAN; MIRN197 MICRORNA, HUMAN; STAT3 PROTEIN, HUMAN;

3' UNTRANSLATED REGION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BCL 2 GENE; BINDING SITE; CANCER PROGNOSIS; CANCER RESISTANCE; CANCER SURVIVAL; CARCINOGENICITY; CHEMOSENSITIZATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYCLIN D1 GENE; DOWN REGULATION; GENE CONTROL; GENE EXPRESSION REGULATION; GENE SILENCING; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LUNG CANCER CELL LINE; LUNG METASTASIS; MALE; MOLECULAR DYNAMICS; MOUSE; NON SMALL CELL LUNG CANCER; NONHUMAN; ONCOGENE C MYC; OVERALL SURVIVAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SURVIVAL RATE; TUMOR GROWTH; UPREGULATION; CARCINOMA, NON-SMALL-CELL LUNG; DRUG RESISTANCE; GENETICS; LUNG NEOPLASMS; METABOLISM; SURVIVAL ANALYSIS; TUMOR CELL LINE;

ANTIGENS, CD274; ANTINEOPLASTIC AGENTS; CARCINOMA, NON-SMALL-CELL LUNG; CDC2-CDC28 KINASES; CELL LINE, TUMOR; DRUG RESISTANCE, NEOPLASM; HUMANS; LUNG NEOPLASMS; MICRORNAS; STAT3 TRANSCRIPTION FACTOR; SURVIVAL ANALYSIS;

EID: 84927005034     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2015.10     Document Type: Article

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