A treat-to-target strategy with methotrexate and intra-articular triamcinolone with or without adalimumab effectively reduces MRI synovitis, osteitis and tenosynovitis and halts structural damage progression in early rheumatoid arthritis: Results from the OPERA randomised controlled trial

Annals of the Rheumatic Diseases

Volumn 74, Issue 5, 2015, Pages 867-875

  Axelsen, Mette Bjørndal ^a,b   Eshed, Iris ^c   Hørslev Petersen, Kim ^d,e   Stengaard Pedersen, Kristian ^f   Hetland, Merete Lund ^a,b   Møller, Jakob ^g   Junker, Peter ^h   Pødenphant, Jan ^b,g   Schlemmer, Annette ^f   Ellingsen, Torkell ⁱ   Ahlquist, Palle ^j   Lindegaard, Hanne ^h   Linauskas, Asta ^k   Dam, Mette Yde ⁱ   Hansen, Ib ^l   Horn, Hans Christian ^j   Ammitzbøll, Christian Gytz ^f   Jørgensen, Anette ^f   Krintel, Sophine B ^a   Raun, Johnny ^d,e   Krogh, Niels S ^m   Johansen, Julia Sidenius ^b,g   Østergaard, Mikkel ^a,b   Slot, Ole ⁿ   Nielsen, Lars Kjær ^h   Skjødt, Henrik ⁿ   Majgaard, Ole ^o   Lorenzen, Tove ^i,j   Kowalski, Marcin ^f,p   Johansen, Inger Lauge ^l   Pedersen, Peter Mosborg ^q   Manilo, Natalia ^r   Bliddal, Henning ^s   Thomsen, Henrik ^a   Boesen, Mikael ^t   more..

^a Mental Health Center Glostrup   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c TEL AVIV UNIVERSITY   (Israel)

^d King Christian the Xth Hospital   (Denmark)

^e UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^f AARHUS UNIVERSITY HOSPITAL   (Denmark)

^g GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^h ODENSE UNIVERSITY HOSPITAL   (Denmark)

ⁱ SILKEBORG REGIONAL HOSPITAL   (Denmark)

^j LILLEBAELT HOSPITAL   (Denmark)

^k NORTH DENMARK REGIONAL HOSPITAL   (Denmark)

^l VIBORG HOSPITAL   (Denmark)

^m Zitelab Aps   (Denmark)

ⁿ UNIVERSITY OF COPENHAGEN   (Denmark)

^o SLAGELSE HOSPITAL   (Denmark)

^p AALBORG UNIVERSITY HOSPITAL   (Denmark)

^q RANDERS REGIONAL HOSPITAL   (Denmark)

^r BISPEBJERG HOSPITAL   (Denmark)

^s FREDERIKSBERG HOSPITAL   (Denmark)

^t Bispebjerg Hospital ^*  (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADALIMUMAB; GADOTERATE MEGLUMINE; METHOTREXATE; PLACEBO; TRIAMCINOLONE HEXACETONIDE; ANTIINFLAMMATORY AGENT; ANTIRHEUMATIC AGENT; MONOCLONAL ANTIBODY; TRIAMCINOLONE;

ADULT; AGED; ARTHROPATHY; ARTICLE; BONE EROSION; CONTROLLED STUDY; DISEASE ACTIVITY; DOUBLE BLIND PROCEDURE; FEMALE; FOLLOW UP; HAND; HUMAN; JOINT SPACE NARROWING; MAJOR CLINICAL STUDY; MALE; METACARPOPHALANGEAL JOINT; MULTICENTER STUDY; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; OSTEITIS; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REMISSION; RHEUMATOID ARTHRITIS; SCORING SYSTEM; SYNOVITIS; TENOSYNOVITIS; VERY ELDERLY; WRIST; ARTHRITIS, RHEUMATOID; CLINICAL PROTOCOL; COMBINATION DRUG THERAPY; COMPLICATION; INTRAARTICULAR DRUG ADMINISTRATION; MIDDLE AGED; PATHOLOGY; PATIENT CARE PLANNING; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME; YOUNG ADULT;

ADALIMUMAB; ADULT; AGED; AGED, 80 AND OVER; ANTI-INFLAMMATORY AGENTS; ANTIBODIES, MONOCLONAL, HUMANIZED; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; CLINICAL PROTOCOLS; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; INJECTIONS, INTRA-ARTICULAR; MAGNETIC RESONANCE IMAGING; MALE; METACARPOPHALANGEAL JOINT; METHOTREXATE; MIDDLE AGED; OSTEITIS; PATIENT CARE PLANNING; SEVERITY OF ILLNESS INDEX; SYNOVITIS; TENOSYNOVITIS; TREATMENT OUTCOME; TRIAMCINOLONE; WRIST JOINT; YOUNG ADULT;

EID: 84926677953     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2013-204537     Document Type: Article

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