Orostachys japonicus inhibits the expression of MMP-2 and MMP-9 mRNA and modulates the expression of iNOS and COX-2 genes in human PMA-differentiated THP-1 cellsvia inhibition of NF-κB and MAPK activation

Molecular Medicine Reports

Volumn 12, Issue 1, 2015, Pages 657-662

  Kim, Young Il ^a   Park, Seung Won ^b   Yoon, Yeo Kwang ^c   Lee, Kyung Wook ^c   Lee, Jang Hoon ^c   Woo, Hong Jung ^c   Kim, Youngchul ^c  

^a Kyung Hee University College of Medicine   (South Korea)

^b Catholic University of Daegu   (South Korea)

^c Kyung Hee University   (South Korea)

Author keywords

Cyclooxygenase 2; Inducible nitric oxide synthase; Matrix metalloproteinase; Mitogen activated protein kinase; Nuclear factor B; Orostachys japonicus

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLOOXYGENASE 2; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; OROSTACHYS JAPONICUS EXTRACT; PHORBOL 13 ACETATE 12 MYRISTATE; PLANT EXTRACT; UNCLASSIFIED DRUG; NOS2 PROTEIN, HUMAN;

ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HERB; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MONOCYTIC LEUKEMIA; MTT ASSAY; OROSTACHYS JAPONICUS; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; THP 1 CELL LINE; WESTERN BLOTTING; BIOSYNTHESIS; CHEMISTRY; CRASSULACEAE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; LEUKEMIA; PATHOLOGY; PHOSPHORYLATION; TUMOR CELL LINE;

OROSTACHYS;

CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL PROLIFERATION; CRASSULACEAE; CYCLOOXYGENASE 2; GENE EXPRESSION REGULATION, LEUKEMIC; HUMANS; LEUKEMIA; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHORYLATION; PLANT EXTRACTS; RNA, MESSENGER; TETRADECANOYLPHORBOL ACETATE;

EID: 84926672170     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.3460     Document Type: Article

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