Image fusion of mass spectrometry and microscopy: A multimodality paradigm for molecular tissue mapping

Nature Methods

Volumn 12, Issue 4, 2015, Pages 366-372

  Van De Plas, Raf ^a,b   Yang, Junhai ^a   Spraggins, Jeffrey ^a   Caprioli, Richard M ^a,c,d  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

^c VANDERBILT UNIVERSITY   (United States)

^d VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACCESS TO INFORMATION; ARTICLE; CASE STUDY; CHEMISTRY; CONFIDENCE INTERVAL; DATA MINING; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IMAGE PROCESSING; ION CURRENT; IRRADIATION; MASS SPECTROMETER; MASS SPECTROMETRY; MATHEMATICAL MODEL; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MEASUREMENT ACCURACY; MICROSCOPY; MOLECULAR IMAGING; MOLECULAR MODEL; MOLECULAR TISSUE MAPPING; MULTIMODAL IMAGING; NEODYMIUM YAG LASER; PARTIAL LEAST SQUARES REGRESSION; PREDICTION; PRIORITY JOURNAL; TISSUE DISTRIBUTION; TISSUE SECTION; TISSUE STRUCTURE; ANIMAL; BRAIN; DEVICES; MOUSE; PROCEDURES; ULTRASTRUCTURE;

ANIMALS; BRAIN; IMAGE PROCESSING, COMPUTER-ASSISTED; MASS SPECTROMETRY; MICE; MICROSCOPY;

EID: 84926520216     PISSN: 15487091     EISSN: 15487105     Source Type: Journal    
DOI: 10.1038/nmeth.3296     Document Type: Article

References (40)

1. Weissleder, R. Scaling down imaging: molecular mapping of cancer in mice. Nat. Rev. Cancer 2, 11-18 (2002).
2. Massoud, T.F. & Gambhir, S.S. Molecular imaging in living subjects: seeing fundamental biological processes in a new light. Genes Dev. 17, 545-580 (2003).
3. Jahn, K.A. et al. Correlative microscopy: providing new understanding in the biomedical and plant sciences. Micron 43, 565-582 (2012).
4. Jacobs, R.E. & Cherry, S.R. Complementary emerging techniques: high-resolution PET and MRI. Curr. Opin. Neurobiol. 11, 621-629 (2001).
5. Chughtai, S. et al. A multimodal mass spectrometry imaging approach for the study of musculoskeletal tissues. Int. J. Mass Spectrom. 325-327, 150-160 (2012).
6. Smith, C. Two microscopes are better than one. Nature 492, 293-297 (2012).
7. Caplan, J., Niethammer, M., Taylor, R.M. II. & Czymmek, K.J. The power of correlative microscopy: multi-modal, multi-scale, multi-dimensional. Curr. Opin. Struct. Biol. 21, 686-693 (2011).
8. Modla, S. & Czymmek, K.J. Correlative microscopy: a powerful tool for exploring neurological cells and tissues. Micron 42, 773-792 (2011).
9. Townsend, D.W. A combined PET/CT scanner: the choices. J. Nucl. Med. 42, 533-534 (2001).
10. Townsend, D.W., Beyer, T. & Blodgett, T.M. PET/CT scanners: a hardware approach to image fusion. Semin. Nucl. Med. 33, 193-204 (2003).
11. Masyuko, R., Lanni, E.J., Sweedler, J.V. & Bohn, P.W. Correlated imaging-a grand challenge in chemical analysis. Analyst 138, 1924-1939 (2013).
12. Bocklitz, T.W. et al. Deeper understanding of biological tissue: quantitative correlation of MALDI-TOF and Raman imaging. Anal. Chem. 85, 10829-10834 (2013).
13. Clarke, F.C. et al. Chemical image fusion. The synergy of FT-NIR and Raman mapping microscopy to enable a more complete visualization of pharmaceutical formulations. Anal. Chem. 73, 2213-2220 (2001).
14. Judenhofer, M.S. et al. Simultaneous PET-MRI: a new approach for functional and morphological imaging. Nat. Med. 14, 459-465 (2008).
15. Glenn, D.R. et al. Correlative light and electron microscopy using cathodoluminescence from nanoparticles with distinguishable colours. Sci. Rep. 2, 865 (2012).
16. Josephson, L., Kircher, M.F., Mahmood, U., Tang, Y. & Weissleder, R. Near-infrared fluorescent nanoparticles as combined MR/optical imaging probes. Bioconjug. Chem. 13, 554-560 (2002).
17. Blum, R.S. & Liu, Z. Multi-sensor Image Fusion and Its Applications (CRC Press, 2005).
18. Bretschneider, T. & Kao, O. in Proc. 1st Online Symp. Electron. Eng. 1-8 (2000).
19. Pohl, C. & Van Genderen, J.L. Multisensor image fusion in remote sensing: concepts, methods and applications. Int. J. Remote Sens. 19, 823-854 (1998).
20. Price, J.C. Combining multispectral data of differing spatial resolution. IEEE Trans. Geosci. Rem. Sens. 37, 1199-1203 (1999).
21. Simone, G., Farina, A., Morabito, F.C., Serpico, S.B. & Bruzzone, L. Image fusion techniques for remote sensing applications. Inf. Fusion 3, 3-15 (2002).
22. Gaemperli, O. et al. Cardiac image fusion from stand-alone SPECT and CT: clinical experience. J. Nucl. Med. 48, 696-703 (2007).
23. Li, H. et al. Object recognition in brain CT-scans: knowledge-based fusion of data from multiple feature extractors. IEEE Trans. Med. Imaging 14, 212-229 (1995).
24. Yang, L., Guo, B.L. & Ni, W. Multimodality medical image fusion based on multiscale geometric analysis of contourlet transform. Neurocomputing 72, 203-211 (2008).
25. Varshney, P.K. et al. in Proc. Int. Conf. Image Proc. 3, 532-536 (IEEE, 1999).
26. Caprioli, R.M., Farmer, T.B. & Gile, J. Molecular imaging of biological samples: localization of peptides and proteins using MALDI-TOF MS. Anal. Chem. 69, 4751-4760 (1997).
27. Stoeckli, M., Chaurand, P., Hallahan, D.E. & Caprioli, R.M. Imaging mass spectrometry: a new technology for the analysis of protein expression in mammalian tissues. Nat. Med. 7, 493-496 (2001).
28. Amstalden van Hove, E.R., Smith, D.F. & Heeren, R. A concise review of mass spectrometry imaging. J. Chromatogr. A 1217, 3946-3954 (2010).
29. Chaurand, P. Imaging mass spectrometry of thin tissue sections: a decade of collective efforts. J. Proteomics 75, 4883-4892 (2012).
30. Norris, J.L. & Caprioli, R.M. Analysis of tissue specimens by matrix-assisted laser desorption/ionization imaging mass spectrometry in biological and clinical research. Chem. Rev. 113, 2309-2342 (2013).
31. Murphy, R.C., Hankin, J.A. & Barkley, R.M. Imaging of lipid species by MALDI mass spectrometry. J. Lipid Res. 50, S317-S322 (2009).
32. Van de Plas, R. Tissue Based Proteomics and Biomarker Discovery-Multivariate Data Mining Strategies for Mass Spectral Imaging. PhD thesis, KU Leuven (2010).
33. Andersson, M., Andren, P. & Caprioli, R.M. in Neuroproteomics (ed. Azalte, O.) Ch. 7, 115-134 (CRC Press, 2009).
34. Franck, J. et al. MALDI mass spectrometry imaging of proteins exceeding 30,000 daltons. Med. Sci. Monit. 16, BR293-BR299 (2010).
35. Bradshaw, R., Bleay, S., Wolstenholme, R., Clench, M.R. & Francese, S. Towards the integration of matrix assisted laser desorption ionisation mass spectrometry imaging into the current fingermark examination workflow. Forensic Sci. Int. 232, 111-124 (2013).
36. Chavez, P.S. Jr., Sides, S.C. & Anderson, J.A. Comparison of three different methods to merge multiresolution and multispectral data-Landsat TM and SPOT panchromatic. Photogramm. Eng. Remote Sensing 57, 295-303 (1991).
37. Garguet-Duport, B., Girel, J., Chassery, J.-M. & Patou, G. The use of multiresolution analysis and wavelets transform for merging SPOT panchromatic and multispectral image data. Photogramm. Eng. Remote Sensing 62, 1057-1066 (1996).
38. Lee, J. & Lee, C. Fast and efficient panchromatic sharpening. IEEE Trans. Geosci. Remote Sens. 48, 155-163 (2010).
39. Draper, N.R., Smith, H. & Pownell, E. Applied Regression Analysis 1st edn. (Wiley, 1966).
40. Wold, S., Sjöström, M. & Eriksson, L. PLS-regression: a basic tool of chemometrics. Chemom. Intell. Lab. Syst. 58, 109-130 (2001).