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Volumn 74, Issue 5, 2015, Pages 851-858

Glucosamine and chondroitin for knee osteoarthritis: A double-blind randomised placebo-controlled clinical trial evaluating single and combination regimens

(34)  Fransen, Marlene a,f   Agaliotis, Maria a,f   Nairn, Lillias a,f   Votrubec, Milana b   Bridgett, Lisa a,f   Su, Steve c,f   Jan, Stephen a,f   March, Lyn a,f   Edmonds, John d,f   Norton, Robyn a,f   Woodward, Mark a   Day, Richard e,f   Buckland Wright, Chris f   Bridges Webb, Charles f   Heritier, Stephane f   Jones, Graeme f   Sambrook, Phillip f   Speechly, Catherine f   Vignon, Eric f   Jovanovic, Gorica g   more..


Author keywords

[No Author keywords available]

Indexed keywords

CHONDROITIN SULFATE; GLUCOSAMINE SULFATE; PLACEBO; GLUCOSAMINE;

EID: 84926454571     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2013-203954     Document Type: Article
Times cited : (157)

References (39)
  • 1
    • 0141920503 scopus 로고    scopus 로고
    • Burden of major musculoskeletal conditions
    • Woolf AD, Pfleger B. Burden of major musculoskeletal conditions. Bull WHO 2003; 81:646-56.
    • (2003) Bull WHO , vol.81 , pp. 646-656
    • Woolf, A.D.1    Pfleger, B.2
  • 2
    • 84871051576 scopus 로고    scopus 로고
    • Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: A systematic analysis for the global burden of disease study 2010
    • Vos T, Flaxman AD, Naghavi M, et al Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012; 380:2163-96.
    • (2012) Lancet , vol.380 , pp. 2163-2196
    • Vos, T.1    Flaxman, A.D.2    Naghavi, M.3
  • 4
    • 85028145170 scopus 로고    scopus 로고
    • 45andUP Study April 2010 release
    • 45andUP Study. The 45 and UP Study Data Book. April 2010 release. 2010.
    • (2010) The 45 and UP Study Data Book
  • 6
    • 34247624271 scopus 로고    scopus 로고
    • Meta-analysis: Chondroitin for osteoarthritis of the knee or hip
    • Reichenbach S, Sterchi R, Scherer M., et al. Meta-analysis: chondroitin for osteoarthritis of the knee or hip. Ann Intern Med 2007; 146:580-90.
    • (2007) Ann Intern Med , vol.146 , pp. 580-590
    • Reichenbach, S.1    Sterchi, R.2    Scherer, M.3
  • 7
    • 77953736595 scopus 로고    scopus 로고
    • Structure-modifying effects of chondroitin sulfate in knee osteoarthritis: An updated meta-analysis of randomized placebo-controlled trials of 2-year duration
    • Hochberg MC. Structure-modifying effects of chondroitin sulfate in knee osteoarthritis: an updated meta-analysis of randomized placebo-controlled trials of 2-year duration. Osteoarthritis Cartilage 2010; 18:S28-31.
    • (2010) Osteoarthritis Cartilage , vol.18 , pp. S28-31
    • Hochberg, M.C.1
  • 8
    • 33344461287 scopus 로고    scopus 로고
    • Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
    • Clegg DO, Reda DJ, Harris C.L., et al. Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis. N Engl J Med 2006; 354:795-808.
    • (2006) N Engl J Med , vol.354 , pp. 795-808
    • Clegg, D.O.1    Reda, D.J.2    Harris, C.L.3
  • 9
    • 54949121728 scopus 로고    scopus 로고
    • The effect of glucosamine and/or chondroitin sulfate on the progression of knee osteoarthritis: A report from the glucosamine/chondroitin arthritis intervention trial
    • Sawitzke AD, Shi H, Finco M.F., et al. The effect of glucosamine and/or chondroitin sulfate on the progression of knee osteoarthritis: a report from the glucosamine/chondroitin arthritis intervention trial. Arthritis Rheum 2008; 58:3183-91.
    • (2008) Arthritis Rheum , vol.58 , pp. 3183-3191
    • Sawitzke, A.D.1    Shi, H.2    Finco, M.F.3
  • 10
    • 77950021805 scopus 로고    scopus 로고
    • OARS recommendations for the management of hip and knee osteoarthritis: Part III: Changes in evidence following systematic cumulative update of research published through january 2009
    • Zhang W, Nuki G, Moskowitz R.W., et al. OARS recommendations for the management of hip and knee osteoarthritis: part III: changes in evidence following systematic cumulative update of research published through January 2009. Osteoarthritis Cartilage 2010; 18:476-99.
    • (2010) Osteoarthritis Cartilage , vol.18 , pp. 476-499
    • Zhang, W.1    Nuki, G.2    Moskowitz, R.W.3
  • 11
    • 40449122299 scopus 로고    scopus 로고
    • Care and management of osteoarthritis in adults: Summary of NICE guidance
    • Conaghan PG, Dickson J, Grant RG Care and management of osteoarthritis in adults: summary of NICE guidance. BMJ 2008; 336:502-3.
    • (2008) BMJ , vol.336 , pp. 502-503
    • Conaghan, P.G.1    Dickson, J.2    Grant, R.G.3
  • 12
    • 3442880702 scopus 로고    scopus 로고
    • Reproducibility of the semi-flexed (MTP) radiographic knee position and automated measurements of medial tibiofemoral joint space width in a multicentre clinical trial of knee osteoarthritis
    • Buckland-Wright J.C., Ward RJ, Peterfy C, et al Reproducibility of the semi-flexed (MTP) radiographic knee position and automated measurements of medial tibiofemoral joint space width in a multicentre clinical trial of knee osteoarthritis. J Rheumatol 2004; 31:1588-97.
    • (2004) J Rheumatol , vol.31 , pp. 1588-1597
    • Buckland-Wright, J.C.1    Ward, R.J.2    Peterfy, C.3
  • 13
    • 0032756151 scopus 로고    scopus 로고
    • Substantial superiority of semiflexed (MTP) views in knee osteoarthritis: A comparative radiographic study, without fluoroscopy, of standing extended, semiflexed (MTP), and schuss views
    • Buckland-Wright J.C., Wolfe F, Ward R.J., et al. Substantial superiority of semiflexed (MTP) views in knee osteoarthritis: a comparative radiographic study, without fluoroscopy, of standing extended, semiflexed (MTP), and Schuss views. J Rheumatol 1999; 26:2664-74.
    • (1999) J Rheumatol , vol.26 , pp. 2664-2674
    • Buckland-Wright, J.C.1    Wolfe, F.2    Ward, R.J.3
  • 14
    • 18644373354 scopus 로고    scopus 로고
    • Selection of knee radiographs for trials of structure-modifying drugs in patients with knee osteoarthritis
    • Conrozier T, Mathieu P, Piperno M., et al. Selection of knee radiographs for trials of structure-modifying drugs in patients with knee osteoarthritis. Arthritis Rheum 2005; 52:1411-17.
    • (2005) Arthritis Rheum , vol.52 , pp. 1411-1417
    • Conrozier, T.1    Mathieu, P.2    Piperno, M.3
  • 15
    • 0345269751 scopus 로고    scopus 로고
    • The self-administered comorbidity questionnaire: A new method to assess comorbidity for clinical and health services research
    • Sangha O, Stucki G, Liang M.H., et al. The Self-Administered Comorbidity Questionnaire: a new method to assess comorbidity for clinical and health services research. Arthritis Rheum 2003; 49:156-63.
    • (2003) Arthritis Rheum , vol.49 , pp. 156-163
    • Sangha, O.1    Stucki, G.2    Liang, M.H.3
  • 16
    • 0024268463 scopus 로고
    • Validation study of WOMAC: A health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee
    • Bellamy N, Buchanan WW, Goldsmith C.H., et al. Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol 1988; 15:1833-40.
    • (1988) J Rheumatol , vol.15 , pp. 1833-1840
    • Bellamy, N.1    Buchanan, W.W.2    Goldsmith, C.H.3
  • 17
    • 0034900260 scopus 로고    scopus 로고
    • Psychometric evaluation of the 12-item short-form health survey (SF-12) in osteoarthritis and rheumatoid arthritis clinical trials
    • Gandhi SK, Salmon JW, Zhao S.Z., et al. Psychometric evaluation of the 12-item short-form health survey (SF-12) in osteoarthritis and rheumatoid arthritis clinical trials. Clinical Therapeutics 2001; 23:1080-98.
    • (2001) Clinical Therapeutics , vol.23 , pp. 1080-1098
    • Gandhi, S.K.1    Salmon, J.W.2    Zhao, S.Z.3
  • 18
    • 0023734553 scopus 로고
    • 50-foot walking time: Critical assessment of an outcome measure in clinical therapeutic trials of antirheumatic drugs
    • Grace EM, Gerecz EM, Kassam Y.B., et al. 50-foot walking time: critical assessment of an outcome measure in clinical therapeutic trials of antirheumatic drugs. Br J Rheumatol 1988; 27:372-4.
    • (1988) Br J Rheumatol , vol.27 , pp. 372-374
    • Grace, E.M.1    Gerecz, E.M.2    Kassam, Y.B.3
  • 19
    • 52149112526 scopus 로고    scopus 로고
    • Head-to-head comparison of the lyon schuss and fixed flexion radiographic techniques. Long-term reproducibility in normal knees and sensitivity to change in osteoarthritic knees
    • Helio Le Graverand M-P, Vignon EP, Brandt KD, et al. Head-to-head comparison of the Lyon Schuss and fixed flexion radiographic techniques. Long-term reproducibility in normal knees and sensitivity to change in osteoarthritic knees. Ann Rheum Dis 2008; 67:1562-6.
    • (2008) Ann Rheum Dis , vol.67 , pp. 1562-1566
    • Le Helio Graverand, M.-P.1    Vignon, E.P.2    Brandt, K.D.3
  • 20
    • 78149407127 scopus 로고    scopus 로고
    • Alignment of the medial tibial plateau affects the rate of joint space narrowing in the osteoarthritic knee
    • Vignon E, Brandt KD, Mercier C, et al Alignment of the medial tibial plateau affects the rate of joint space narrowing in the osteoarthritic knee. Osteoarthritis Cartilage 2010; 18:1436-40.
    • (2010) Osteoarthritis Cartilage , vol.18 , pp. 1436-1440
    • Vignon, E.1    Brandt, K.D.2    Mercier, C.3
  • 21
    • 62949246527 scopus 로고
    • Radiological assessment of osteo-arthrosis
    • Kellgren JH, Lawrence JS Radiological assessment of osteo-arthrosis. Ann Rheum Dis 1957; 16:494-502.
    • (1957) Ann Rheum Dis , vol.16 , pp. 494-502
    • Kellgren, J.H.1    Lawrence, J.S.2
  • 22
    • 79959846767 scopus 로고    scopus 로고
    • Risk factors predictive of joint replacement in a 2-year multicentre clinical trial in knee osteoarthritis using MRI: Results from over 6 years of observation
    • Raynauld JP, Martel-Pelletier J, Haraoui B., et al. Risk factors predictive of joint replacement in a 2-year multicentre clinical trial in knee osteoarthritis using MRI: results from over 6 years of observation. Ann Rheum Dis 2011; 70:1382-8.
    • (2011) Ann Rheum Dis , vol.70 , pp. 1382-1388
    • Raynauld, J.P.1    Martel-Pelletier, J.2    Haraoui, B.3
  • 23
    • 70149088596 scopus 로고    scopus 로고
    • Glucosamine therapy for knee osteoarthritis: Pharmacokinetic considerations
    • Altman RD. Glucosamine therapy for knee osteoarthritis: pharmacokinetic considerations. Expert Rev Clin Pharmacol 2009; 2:359-71.
    • (2009) Expert Rev Clin Pharmacol , vol.2 , pp. 359-371
    • Altman, R.D.1
  • 24
    • 77955444703 scopus 로고    scopus 로고
    • Clinical efficacy and safety of glucosamine, chondroitin sulphate, their combination, celecoxib or placebo taken to treat osteoarthritis of the knee: 2-year results from GAIT
    • Sawitzke AD, Shi H, Finco M.F., et al. Clinical efficacy and safety of glucosamine, chondroitin sulphate, their combination, celecoxib or placebo taken to treat osteoarthritis of the knee: 2-year results from GAIT. Ann Rheum Dis 2010; 69:1459-64.
    • (2010) Ann Rheum Dis , vol.69 , pp. 1459-1464
    • Sawitzke, A.D.1    Shi, H.2    Finco, M.F.3
  • 25
    • 0037078298 scopus 로고    scopus 로고
    • Glucosamine sulphate use and delay of progression of knee osteoarthritis. A 3 year, randomized, placebo-controlled, double-blind study
    • Pavelka K, Gatterova J, Olejarova M., et al. Glucosamine sulphate use and delay of progression of knee osteoarthritis. A 3 year, randomized, placebo-controlled, double-blind study. Arch Intern Med 2002; 162:2113-23.
    • (2002) Arch Intern Med , vol.162 , pp. 2113-2123
    • Pavelka, K.1    Gatterova, J.2    Olejarova, M.3
  • 26
    • 0035956653 scopus 로고    scopus 로고
    • Long-term effects of glucosamine sulphate on osteoarthritis progression: A randomised, placebo-controlled clinical trial
    • Reginster JY, Deroisy R, Rovati L.C., et al. Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial. Lancet 2001; 357:251-6.
    • (2001) Lancet , vol.357 , pp. 251-256
    • Reginster, J.Y.1    Deroisy, R.2    Rovati, L.C.3
  • 27
    • 41149165099 scopus 로고    scopus 로고
    • Understanding the pain experience in hip and knee osteoarthritis - An OARSI/OMERACT initiative
    • Hawker GA, Stewart L, French M.R., et al. Understanding the pain experience in hip and knee osteoarthritis - an OARSI/OMERACT initiative. Osteoarthritis Cart 2008; 16:415-22.
    • (2008) Osteoarthritis Cart , vol.16 , pp. 415-422
    • Hawker, G.A.1    Stewart, L.2    French, M.R.3
  • 28
    • 77950273246 scopus 로고    scopus 로고
    • CONSORT 2010 explanation and elaboration: Updated guidelines for reporting parallel group randomised trial
    • Moher D, Hopewell S, Schulz K.F., et al. CONSORT 2010 Explanation and Elaboration: updated guidelines for reporting parallel group randomised trial. BMJ 2010; 340:c869.
    • (2010) BMJ , vol.340 , pp. c869
    • Moher, D.1    Hopewell, S.2    Schulz, K.F.3
  • 29
    • 77957342022 scopus 로고    scopus 로고
    • Effects of glucosamine, chondroitin, or placebo in patients with osteoarthritis of hip or knee: Network meta-analysis
    • Wandel S, Juni P, Tendal B., et al. Effects of glucosamine, chondroitin, or placebo in patients with osteoarthritis of hip or knee: network meta-analysis. BMJ 2010; 341: c4675.
    • (2010) BMJ , vol.341
    • Wandel, S.1    Juni, P.2    Tendal, B.3
  • 30
    • 37848999867 scopus 로고    scopus 로고
    • Chondroitin and glucosamine sulfate in combination decrease the pro-resorptive properties of human osteoarthritis subcondral bone osteoblasts: A basic science study
    • Tat SK, Pelletier JP, Verges J, et al Chondroitin and glucosamine sulfate in combination decrease the pro-resorptive properties of human osteoarthritis subcondral bone osteoblasts: a basic science study. Arthritis Res Ther 2007; 9:R117.
    • (2007) Arthritis Res Ther , vol.9 , pp. R117
    • Tat, S.K.1    Pelletier, J.P.2    Verges, J.3
  • 31
    • 50849124454 scopus 로고    scopus 로고
    • Potential effects of chondroitin sulfate on joint swelling: A GAIT report
    • Hochberg MC, Clegg DO Potential effects of chondroitin sulfate on joint swelling: a GAIT report. Osteoarthritis Cart 2008; 16:S22-4.
    • (2008) Osteoarthritis Cart , vol.16 , pp. S22-4
    • Hochberg, M.C.1    Clegg, D.O.2
  • 32
    • 79955794264 scopus 로고    scopus 로고
    • Chondroitin sulphate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starting as early as 6 months after initiation of therapy: A randomised, double-blind, placebo-controlled pilot study using MRI
    • Wildi LM, Raynauld J-P, Martel-Pelletier J, et al. Chondroitin sulphate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starting as early as 6 months after initiation of therapy: a randomised, double-blind, placebo-controlled pilot study using MRI. Ann Rheum Dis 2011; 70:982-9.
    • (2011) Ann Rheum Dis , vol.70 , pp. 982-989
    • Wildi, L.M.1    Raynauld, J.-P.2    Martel-Pelletier, J.3
  • 33
    • 59649101384 scopus 로고    scopus 로고
    • Glucosamine and chondroitin for osteoarthritis
    • Huskisson EC. Glucosamine and chondroitin for osteoarthritis. J Int Med Res 2008; 36:1161-79.
    • (2008) J Int Med Res , vol.36 , pp. 1161-1179
    • Huskisson, E.C.1
  • 34
    • 79961164393 scopus 로고    scopus 로고
    • The glucosamine controversy; a pharmacokinetic issue
    • Aghazadeh-Habashi A., Jamali G. The glucosamine controversy; a pharmacokinetic issue. J Pharm Pharmaceut Sci 2011; 14:264-73.
    • (2011) J Pharm Pharmaceut Sci , vol.14 , pp. 264-273
    • Aghazadeh-Habashi, A.1    Jamali, G.2
  • 35
    • 78650941135 scopus 로고    scopus 로고
    • Glucosamine and chondroitin sulfate
    • Miller KL, Clegg DO Glucosamine and chondroitin sulfate. Rheum Dis Clin N Am 2011; 37:103-18.
    • (2011) Rheum Dis Clin N Am , vol.37 , pp. 103-118
    • Miller, K.L.1    Clegg, D.O.2
  • 36
    • 0034914603 scopus 로고    scopus 로고
    • Sulfate could mediate the therapeutic effect of glucosamine sulfate
    • Hoffer LJ, Kaplan LN, Hamadeh M.J., et al. Sulfate could mediate the therapeutic effect of glucosamine sulfate. Metabolism 2001; 50:767-70.
    • (2001) Metabolism , vol.50 , pp. 767-770
    • Hoffer, L.J.1    Kaplan, L.N.2    Hamadeh, M.J.3
  • 37
    • 0025454569 scopus 로고
    • High susceptibility of human articular cartilage glycosaminoglycan synthesis to changes in inorganic sulfate availability
    • van der Kraan PM, Vitters EL, de Vries BJ, et al. High susceptibility of human articular cartilage glycosaminoglycan synthesis to changes in inorganic sulfate availability. J Orthop Res 1990; 8:565-71.
    • (1990) J Orthop Res , vol.8 , pp. 565-571
    • Van Der Kraan, P.M.1    Vitters, E.L.2    De Vries, B.J.3
  • 38
    • 27944467361 scopus 로고    scopus 로고
    • Three year joint space narrowing predicts long term incidence of knee surgery in patients with osteoarthritis: An eight year prospective follow up study
    • Bruyere O, Richy F, Reginster JY Three year joint space narrowing predicts long term incidence of knee surgery in patients with osteoarthritis: an eight year prospective follow up study. Ann Rheum Dis 2005; 64:1727-30.
    • (2005) Ann Rheum Dis , vol.64 , pp. 1727-1730
    • Bruyere, O.1    Richy, F.2    Reginster, J.Y.3
  • 39
    • 0347236887 scopus 로고    scopus 로고
    • Longitudinal study of changes in tibial and femoral cartilage in knee osteoarthritis
    • Cicuttini FM, Wluka AE, Wang Y, et al Longitudinal study of changes in tibial and femoral cartilage in knee osteoarthritis. Arthritis Rheum 2004; 50:94-7.
    • (2004) Arthritis Rheum , vol.50 , pp. 94-97
    • Cicuttini, F.M.1    Wluka, A.E.2    Wang, Y.3


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