-
1
-
-
84858041889
-
-
Centers for Disease Control and Prevention. National diabetes fact sheet U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (accessed 14 August 2014)
-
Centers for Disease Control and Prevention. National diabetes fact sheet, 2011: national estimates and general information on diabetes and prediabetes in the United States. U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, http://www.cdc.gov/diabetes/pubs/pdf/ndfs-2011.pdf (accessed 14 August 2014).
-
(2011)
National Estimates and General Information on Diabetes and Prediabetes in the United States
-
-
-
2
-
-
0034641568
-
Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): Prospective observational study
-
Stratton IM, Adler AI, Neil HA, et al. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study. BMJ. 2000 ; 321: 405-412
-
(2000)
BMJ
, vol.321
, pp. 405-412
-
-
Stratton, I.M.1
Adler, A.I.2
Neil, H.A.3
-
3
-
-
84866687503
-
Individualizing targets and tactics for high-risk patients with type 2 diabetes: Practical lessons from ACCORD and other cardiovascular trials
-
Riddle MC, Karl DM. Individualizing targets and tactics for high-risk patients with type 2 diabetes: practical lessons from ACCORD and other cardiovascular trials. Diabetes Care. 2012 ; 35: 2100-2107
-
(2012)
Diabetes Care
, vol.35
, pp. 2100-2107
-
-
Riddle, M.C.1
Karl, D.M.2
-
4
-
-
33846006173
-
The incretin system: Glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
-
Drucker DJ, Nauck MA. The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes. Lancet. 2006 ; 368: 1696-1705
-
(2006)
Lancet
, vol.368
, pp. 1696-1705
-
-
Drucker, D.J.1
Nauck, M.A.2
-
5
-
-
84860252744
-
The increased dipeptidyl peptidase-4 activity is not counteracted by optimized glucose control in type 2 diabetes, but is lower in metformin-treated patients
-
Fadini GP, Albiero M, Menegazzo L, et al. The increased dipeptidyl peptidase-4 activity is not counteracted by optimized glucose control in type 2 diabetes, but is lower in metformin-treated patients. Diabetes Obes Metab. 2012 ; 14: 518-522
-
(2012)
Diabetes Obes Metab
, vol.14
, pp. 518-522
-
-
Fadini, G.P.1
Albiero, M.2
Menegazzo, L.3
-
6
-
-
80052096595
-
Dipeptidyl peptidase 4 is a novel adipokine potentially linking obesity to the metabolic syndrome
-
Lamers D, Famulla S, Wronkowitz N, et al. Dipeptidyl peptidase 4 is a novel adipokine potentially linking obesity to the metabolic syndrome. Diabetes. 2011 ; 60: 1917-1925
-
(2011)
Diabetes
, vol.60
, pp. 1917-1925
-
-
Lamers, D.1
Famulla, S.2
Wronkowitz, N.3
-
7
-
-
9444226473
-
SDF-1 involvement in endothelial phenotype and ischemia-induced recruitment of bone marrow progenitor cells
-
De Falco E, Porcelli D, Torella AR, et al. SDF-1 involvement in endothelial phenotype and ischemia-induced recruitment of bone marrow progenitor cells. Blood. 2004 ; 104: 3472-3482
-
(2004)
Blood
, vol.104
, pp. 3472-3482
-
-
De Falco, E.1
Porcelli, D.2
Torella, A.R.3
-
8
-
-
84555209178
-
Dipeptidyl peptidase IV inhibition improves cardiorenal function in overpacing-induced heart failure
-
Gomez N, Touihri K, Matheeussen V, et al. Dipeptidyl peptidase IV inhibition improves cardiorenal function in overpacing-induced heart failure. Eur J Heart Fail. 2012 ; 14: 14-21
-
(2012)
Eur J Heart Fail
, vol.14
, pp. 14-21
-
-
Gomez, N.1
Touihri, K.2
Matheeussen, V.3
-
9
-
-
34249902025
-
Dipeptidyl peptidase-4 inhibition and the treatment of type 2 diabetes: Preclinical biology and mechanisms of action
-
Drucker DJ. Dipeptidyl peptidase-4 inhibition and the treatment of type 2 diabetes: preclinical biology and mechanisms of action. Diabetes Care. 2007 ; 30: 1335-1343
-
(2007)
Diabetes Care
, vol.30
, pp. 1335-1343
-
-
Drucker, D.J.1
-
10
-
-
0027104080
-
Bradykinin metabolism pathway in the rat pulmonary circulation
-
Pesquero JB, Jubilut GN, Lindsey CJ, et al. Bradykinin metabolism pathway in the rat pulmonary circulation. J Hypertens. 1992 ; 10: 1471-1478
-
(1992)
J Hypertens
, vol.10
, pp. 1471-1478
-
-
Pesquero, J.B.1
Jubilut, G.N.2
Lindsey, C.J.3
-
11
-
-
0033048762
-
Bradykinin stimulates tissue plasminogen activator release in human vasculature
-
Brown NJ, Gainer JV, Stein CM, et al. Bradykinin stimulates tissue plasminogen activator release in human vasculature. Hypertension. 1999 ; 33: 1431-1435
-
(1999)
Hypertension
, vol.33
, pp. 1431-1435
-
-
Brown, N.J.1
Gainer, J.V.2
Stein, C.M.3
-
12
-
-
33644814714
-
Stimulated tissue plasminogen activator release as a marker of endothelial function in humans
-
Oliver JJ, Webb DJ, Newby DE. Stimulated tissue plasminogen activator release as a marker of endothelial function in humans. Arterioscler Thromb Vasc Biol. 2005 ; 25: 2470-2479
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 2470-2479
-
-
Oliver, J.J.1
Webb, D.J.2
Newby, D.E.3
-
13
-
-
0034060107
-
Enhanced ganglionic responses to substance P in spontaneously hypertensive rats
-
Hancock JC, Lindsay GW. Enhanced ganglionic responses to substance P in spontaneously hypertensive rats. Peptides. 2000 ; 21: 535-541
-
(2000)
Peptides
, vol.21
, pp. 535-541
-
-
Hancock, J.C.1
Lindsay, G.W.2
-
14
-
-
75149129619
-
Cardiovascular disease in type 2 diabetes from population to man to mechanisms: The Kelly West Award Lecture 2008
-
Laakso M. Cardiovascular disease in type 2 diabetes from population to man to mechanisms: the Kelly West Award Lecture 2008. Diabetes Care. 2010 ; 33: 442-449
-
(2010)
Diabetes Care
, vol.33
, pp. 442-449
-
-
Laakso, M.1
-
15
-
-
79953192995
-
HDL and cardiovascular disease: Atherogenic and atheroprotective mechanisms
-
Navab M, Reddy ST, Van Lenten BJ, et al. HDL and cardiovascular disease: atherogenic and atheroprotective mechanisms. Nat Rev Cardiol. 2011 ; 8: 222-232
-
(2011)
Nat Rev Cardiol
, vol.8
, pp. 222-232
-
-
Navab, M.1
Reddy, S.T.2
Van Lenten, B.J.3
-
16
-
-
37349021003
-
Subendothelial lipoprotein retention as the initiating process in atherosclerosis: Update and therapeutic implications
-
Tabas I, Williams KJ, Boren J. Subendothelial lipoprotein retention as the initiating process in atherosclerosis: update and therapeutic implications. Circulation. 2007 ; 116: 1832-1844
-
(2007)
Circulation
, vol.116
, pp. 1832-1844
-
-
Tabas, I.1
Williams, K.J.2
Boren, J.3
-
17
-
-
0034681949
-
Endothelial dysfunction is detectable in young normotensive first-degree relatives of subjects with type 2 diabetes in association with insulin resistance
-
Balletshofer BM, Rittig K, Enderle MD, et al. Endothelial dysfunction is detectable in young normotensive first-degree relatives of subjects with type 2 diabetes in association with insulin resistance. Circulation. 2000 ; 101: 1780-1784
-
(2000)
Circulation
, vol.101
, pp. 1780-1784
-
-
Balletshofer, B.M.1
Rittig, K.2
Enderle, M.D.3
-
18
-
-
0035053234
-
Clinical review 124: Diabetic dyslipidemia: Causes and consequences
-
Goldberg IJ. Clinical review 124: diabetic dyslipidemia: causes and consequences. J Clin Endocrinol Metab. 2001 ; 86: 965-971
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 965-971
-
-
Goldberg, I.J.1
-
19
-
-
80052041028
-
Gut-liver interaction in triglyceride-rich lipoprotein metabolism
-
Xiao C, Hsieh J, Adeli K, et al. Gut-liver interaction in triglyceride-rich lipoprotein metabolism. Am J Physiol Endocrinol Metab. 2011 ; 301: E429 - E446
-
(2011)
Am J Physiol Endocrinol Metab
, vol.301
, pp. 429-E446
-
-
Xiao, C.1
Hsieh, J.2
Adeli, K.3
-
20
-
-
79957920754
-
Inflammatory links between obesity and metabolic disease
-
Lumeng CN, Saltiel AR. Inflammatory links between obesity and metabolic disease. J Clin Invest. 2011 ; 121: 2111-2117
-
(2011)
J Clin Invest
, vol.121
, pp. 2111-2117
-
-
Lumeng, C.N.1
Saltiel, A.R.2
-
21
-
-
0037109184
-
Inflammatory cytokine concentrations are acutely increased by hyperglycemia in humans: Role of oxidative stress
-
Esposito K, Nappo F, Marfella R, et al. Inflammatory cytokine concentrations are acutely increased by hyperglycemia in humans: role of oxidative stress. Circulation. 2002 ; 106: 2067-2072
-
(2002)
Circulation
, vol.106
, pp. 2067-2072
-
-
Esposito, K.1
Nappo, F.2
Marfella, R.3
-
22
-
-
2942733214
-
Role of endothelial dysfunction in atherosclerosis
-
Davignon J, Ganz P. Role of endothelial dysfunction in atherosclerosis. Circulation. 2004 ; 109: III27 - III32
-
(2004)
Circulation
, vol.109
, pp. 27-III32
-
-
Davignon, J.1
Ganz, P.2
-
23
-
-
61849099312
-
Endothelial function predicts progression of carotid intima-media thickness
-
Halcox JP, Donald AE, Ellins E, et al. Endothelial function predicts progression of carotid intima-media thickness. Circulation. 2009 ; 119: 1005-1012
-
(2009)
Circulation
, vol.119
, pp. 1005-1012
-
-
Halcox, J.P.1
Donald, A.E.2
Ellins, E.3
-
24
-
-
34248196019
-
Brachial flow-mediated dilation predicts incident cardiovascular events in older adults: The Cardiovascular Health Study
-
Yeboah J, Crouse JR, Hsu FC, et al. Brachial flow-mediated dilation predicts incident cardiovascular events in older adults: the Cardiovascular Health Study. Circulation. 2007 ; 115: 2390-2397
-
(2007)
Circulation
, vol.115
, pp. 2390-2397
-
-
Yeboah, J.1
Crouse, J.R.2
Hsu, F.C.3
-
25
-
-
0035180299
-
Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site
-
Du XL, Edelstein D, Dimmeler S, et al. Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site. J Clin Invest. 2001 ; 108: 1341-1348
-
(2001)
J Clin Invest
, vol.108
, pp. 1341-1348
-
-
Du, X.L.1
Edelstein, D.2
Dimmeler, S.3
-
26
-
-
0032080628
-
Leukocyte-endothelial interaction is augmented by high glucose concentrations and hyperglycemia in a NF-kB-dependent fashion
-
Morigi M, Angioletti S, Imberti B, et al. Leukocyte-endothelial interaction is augmented by high glucose concentrations and hyperglycemia in a NF-kB-dependent fashion. J Clin Invest. 1998 ; 101: 1905-1915
-
(1998)
J Clin Invest
, vol.101
, pp. 1905-1915
-
-
Morigi, M.1
Angioletti, S.2
Imberti, B.3
-
27
-
-
10744221815
-
Clinical correlates and heritability of flow-mediated dilation in the community: The Framingham Heart Study
-
Benjamin EJ, Larson MG, Keyes MJ, et al. Clinical correlates and heritability of flow-mediated dilation in the community: the Framingham Heart Study. Circulation. 2004 ; 109: 613-619
-
(2004)
Circulation
, vol.109
, pp. 613-619
-
-
Benjamin, E.J.1
Larson, M.G.2
Keyes, M.J.3
-
28
-
-
0141615827
-
Diabetes and vascular disease: Pathophysiology, clinical consequences, and medical therapy: Part i
-
Creager MA, Luscher TF, Cosentino F, et al. Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part I. Circulation. 2003 ; 108: 1527-1532
-
(2003)
Circulation
, vol.108
, pp. 1527-1532
-
-
Creager, M.A.1
Luscher, T.F.2
Cosentino, F.3
-
29
-
-
4644351335
-
Meta-analysis: Glycosylated hemoglobin and cardiovascular disease in diabetes mellitus
-
Selvin E, Marinopoulos S, Berkenblit G, et al. Meta-analysis: glycosylated hemoglobin and cardiovascular disease in diabetes mellitus. Ann Intern Med. 2004 ; 141: 421-431
-
(2004)
Ann Intern Med
, vol.141
, pp. 421-431
-
-
Selvin, E.1
Marinopoulos, S.2
Berkenblit, G.3
-
30
-
-
77649329576
-
Glycated hemoglobin, diabetes, and cardiovascular risk in nondiabetic adults
-
Selvin E, Steffes MW, Zhu H, et al. Glycated hemoglobin, diabetes, and cardiovascular risk in nondiabetic adults. N Engl J Med. 2010 ; 362: 800-811
-
(2010)
N Engl J Med
, vol.362
, pp. 800-811
-
-
Selvin, E.1
Steffes, M.W.2
Zhu, H.3
-
31
-
-
84857670631
-
Differentiating among incretin-based therapies in the management of patients with type 2 diabetes mellitus
-
Cobble M. Differentiating among incretin-based therapies in the management of patients with type 2 diabetes mellitus. Diabetol Metab Syndr. 2012 ; 4: 8
-
(2012)
Diabetol Metab Syndr
, vol.4
, pp. 8
-
-
Cobble, M.1
-
32
-
-
79955752170
-
Comparative effectiveness and safety of medications for type 2 diabetes: An update including new drugs and 2-drug combinations
-
Bennett WL, Maruthur NM, Singh S, et al. Comparative effectiveness and safety of medications for type 2 diabetes: an update including new drugs and 2-drug combinations. Ann Intern Med. 2011 ; 154: 602-613
-
(2011)
Ann Intern Med
, vol.154
, pp. 602-613
-
-
Bennett, W.L.1
Maruthur, N.M.2
Singh, S.3
-
33
-
-
84860204551
-
Cardiovascular biology of the incretin system
-
Ussher JR, Drucker DJ. Cardiovascular biology of the incretin system. Endocr Rev. 2012 ; 33: 187-215
-
(2012)
Endocr Rev
, vol.33
, pp. 187-215
-
-
Ussher, J.R.1
Drucker, D.J.2
-
34
-
-
77956230708
-
Exenatide suppresses postprandial elevations in lipids and lipoproteins in individuals with impaired glucose tolerance and recent onset type 2 diabetes mellitus
-
Schwartz EA, Koska J, Mullin MP, et al. Exenatide suppresses postprandial elevations in lipids and lipoproteins in individuals with impaired glucose tolerance and recent onset type 2 diabetes mellitus. Atherosclerosis. 2010 ; 212: 217-222
-
(2010)
Atherosclerosis
, vol.212
, pp. 217-222
-
-
Schwartz, E.A.1
Koska, J.2
Mullin, M.P.3
-
35
-
-
33746690405
-
Vildagliptin therapy reduces postprandial intestinal triglyceride-rich lipoprotein particles in patients with type 2 diabetes
-
Matikainen N, Manttari S, Schweizer A, et al. Vildagliptin therapy reduces postprandial intestinal triglyceride-rich lipoprotein particles in patients with type 2 diabetes. Diabetologia. 2006 ; 49: 2049-2057
-
(2006)
Diabetologia
, vol.49
, pp. 2049-2057
-
-
Matikainen, N.1
Manttari, S.2
Schweizer, A.3
-
36
-
-
55549136417
-
Effects of exenatide versus sitagliptin on postprandial glucose, insulin and glucagon secretion, gastric emptying, and caloric intake: A randomized, cross-over study
-
DeFronzo RA, Okerson T, Viswanathan P, et al. Effects of exenatide versus sitagliptin on postprandial glucose, insulin and glucagon secretion, gastric emptying, and caloric intake: a randomized, cross-over study. Curr Med Res Opin. 2008 ; 24: 2943-2952
-
(2008)
Curr Med Res Opin
, vol.24
, pp. 2943-2952
-
-
Defronzo, R.A.1
Okerson, T.2
Viswanathan, P.3
-
37
-
-
84859463659
-
Lowering of postprandial lipids in individuals with type 2 diabetes treated with alogliptin and/or pioglitazone: A randomised double-blind placebo-controlled study
-
Eliasson B, Moller-Goede D, Eeg-Olofsson K, et al. Lowering of postprandial lipids in individuals with type 2 diabetes treated with alogliptin and/or pioglitazone: a randomised double-blind placebo-controlled study. Diabetologia. 2012 ; 55: 915-925
-
(2012)
Diabetologia
, vol.55
, pp. 915-925
-
-
Eliasson, B.1
Moller-Goede, D.2
Eeg-Olofsson, K.3
-
38
-
-
84857903646
-
DPP-4 inhibitors and lipids: Systematic review and meta-analysis
-
Monami M, Lamanna C, Desideri CM, et al. DPP-4 inhibitors and lipids: systematic review and meta-analysis. Adv Ther. 2012 ; 29: 14-25
-
(2012)
Adv Ther
, vol.29
, pp. 14-25
-
-
Monami, M.1
Lamanna, C.2
Desideri, C.M.3
-
39
-
-
79959773411
-
DPP-4 inhibitors: Impact on glycemic control and cardiovascular risk factors
-
Dicker D. DPP-4 inhibitors: impact on glycemic control and cardiovascular risk factors. Diabetes Care. 2011 ; 34: S276 - S278
-
(2011)
Diabetes Care
, vol.34
, pp. 276-S278
-
-
Dicker, D.1
-
40
-
-
84871936025
-
Dipeptidyl peptidase-4 inhibitors and cardiovascular risk: A meta-analysis of randomized clinical trials
-
Monami M, Ahren B, Dicembrini I, et al. Dipeptidyl peptidase-4 inhibitors and cardiovascular risk: a meta-analysis of randomized clinical trials. Diabetes Obes Metab. 2013 ; 15: 112-120
-
(2013)
Diabetes Obes Metab
, vol.15
, pp. 112-120
-
-
Monami, M.1
Ahren, B.2
Dicembrini, I.3
-
41
-
-
84870053428
-
Dipeptidyl peptidase-4 inhibition with saxagliptin enhanced nitric oxide release and reduced blood pressure and sICAM-1 levels in hypertensive rats
-
Mason RP, Jacob RF, Kubant R, et al. Dipeptidyl peptidase-4 inhibition with saxagliptin enhanced nitric oxide release and reduced blood pressure and sICAM-1 levels in hypertensive rats. J Cardiovasc Pharmacol. 2012 ; 60: 467-473
-
(2012)
J Cardiovasc Pharmacol
, vol.60
, pp. 467-473
-
-
Mason, R.P.1
Jacob, R.F.2
Kubant, R.3
-
42
-
-
80053204667
-
Effect of enhanced glycemic control with saxagliptin on endothelial nitric oxide release and CD40 levels in obese rats
-
Mason RP, Jacob RF, Kubant R, et al. Effect of enhanced glycemic control with saxagliptin on endothelial nitric oxide release and CD40 levels in obese rats. J Atheroscler Thromb. 2011 ; 18: 774-783
-
(2011)
J Atheroscler Thromb
, vol.18
, pp. 774-783
-
-
Mason, R.P.1
Jacob, R.F.2
Kubant, R.3
-
43
-
-
83455230038
-
Vildagliptin improves endothelium-dependent vasodilatation in type 2 diabetes
-
Van Poppel PC, Netea MG, Smits P, et al. Vildagliptin improves endothelium-dependent vasodilatation in type 2 diabetes. Diabetes Care. 2011 ; 34: 2072-2077
-
(2011)
Diabetes Care
, vol.34
, pp. 2072-2077
-
-
Van Poppel, P.C.1
Netea, M.G.2
Smits, P.3
-
44
-
-
84876780409
-
Dipeptidyl peptidase-4 inhibitor, sitagliptin, improves endothelial dysfunction in association with its anti-inflammatory effects in patients with coronary artery disease and uncontrolled diabetes
-
Matsubara J, Sugiyama S, Akiyama E, et al. Dipeptidyl peptidase-4 inhibitor, sitagliptin, improves endothelial dysfunction in association with its anti-inflammatory effects in patients with coronary artery disease and uncontrolled diabetes. Circ J. 2013 ; 77: 1337-1344
-
(2013)
Circ J
, vol.77
, pp. 1337-1344
-
-
Matsubara, J.1
Sugiyama, S.2
Akiyama, E.3
-
45
-
-
84884198401
-
Dipeptidyl peptidase-4 inhibitors attenuate endothelial function as evaluated by flow-mediated vasodilatation in type 2 diabetic patients
-
Ayaori M, Iwakami N, Uto-Kondo H, et al. Dipeptidyl peptidase-4 inhibitors attenuate endothelial function as evaluated by flow-mediated vasodilatation in type 2 diabetic patients. J Am Heart Assoc. 2013 ; 2: e003277
-
(2013)
J Am Heart Assoc
, vol.2
, pp. 003277
-
-
Ayaori, M.1
Iwakami, N.2
Uto-Kondo, H.3
-
46
-
-
80051785333
-
DPP-4 (CD26) inhibitor alogliptin inhibits atherosclerosis in diabetic apolipoprotein E-deficient mice
-
Ta NN, Schuyler CA, Li Y, et al. DPP-4 (CD26) inhibitor alogliptin inhibits atherosclerosis in diabetic apolipoprotein E-deficient mice. J Cardiovasc Pharmacol. 2011 ; 58: 157-166
-
(2011)
J Cardiovasc Pharmacol
, vol.58
, pp. 157-166
-
-
Ta, N.N.1
Schuyler, C.A.2
Li, Y.3
-
47
-
-
81855222104
-
Long-term dipeptidyl-peptidase 4 inhibition reduces atherosclerosis and inflammation via effects on monocyte recruitment and chemotaxis
-
Shah Z, Kampfrath T, Deiuliis JA, et al. Long-term dipeptidyl-peptidase 4 inhibition reduces atherosclerosis and inflammation via effects on monocyte recruitment and chemotaxis. Circulation. 2011 ; 124: 2338-2349
-
(2011)
Circulation
, vol.124
, pp. 2338-2349
-
-
Shah, Z.1
Kampfrath, T.2
Deiuliis, J.A.3
-
48
-
-
77958195997
-
The oral dipeptidyl peptidase-4 inhibitor sitagliptin increases circulating endothelial progenitor cells in patients with type 2 diabetes: Possible role of stromal-derived factor-1α
-
Fadini GP, Boscaro E, Albiero M, et al. The oral dipeptidyl peptidase-4 inhibitor sitagliptin increases circulating endothelial progenitor cells in patients with type 2 diabetes: possible role of stromal-derived factor-1α. Diabetes Care. 2010 ; 33: 1607-1609
-
(2010)
Diabetes Care
, vol.33
, pp. 1607-1609
-
-
Fadini, G.P.1
Boscaro, E.2
Albiero, M.3
-
49
-
-
84875054251
-
Decreased carotid atherosclerotic process by control of daily acute glucose fluctuations in diabetic patients treated by DPP-IV inhibitors
-
Barbieri M, Rizzo MR, Marfella R, et al. Decreased carotid atherosclerotic process by control of daily acute glucose fluctuations in diabetic patients treated by DPP-IV inhibitors. Atherosclerosis. 2013 ; 227: 349-354
-
(2013)
Atherosclerosis
, vol.227
, pp. 349-354
-
-
Barbieri, M.1
Rizzo, M.R.2
Marfella, R.3
-
50
-
-
77951168113
-
Genetic deletion or pharmacological inhibition of dipeptidyl peptidase-4 improves cardiovascular outcomes after myocardial infarction in mice
-
Sauve M, Ban K, Momen MA, et al. Genetic deletion or pharmacological inhibition of dipeptidyl peptidase-4 improves cardiovascular outcomes after myocardial infarction in mice. Diabetes. 2010 ; 59: 1063-1073
-
(2010)
Diabetes
, vol.59
, pp. 1063-1073
-
-
Sauve, M.1
Ban, K.2
Momen, M.A.3
-
51
-
-
81355124070
-
Effects of DPP-4 inhibitors on the heart in a rat model of uremic cardiomyopathy
-
Chaykovska L, Von Websky K, Rahnenfuhrer J, et al. Effects of DPP-4 inhibitors on the heart in a rat model of uremic cardiomyopathy. PLoS One. 2011 ; 6: e27861
-
(2011)
PLoS One
, vol.6
, pp. 27861
-
-
Chaykovska, L.1
Von Websky, K.2
Rahnenfuhrer, J.3
-
52
-
-
80053358548
-
Early and late effects of the DPP-4 inhibitor vildagliptin in a rat model of post-myocardial infarction heart failure
-
Yin M, Sillje HH, Meissner M, et al. Early and late effects of the DPP-4 inhibitor vildagliptin in a rat model of post-myocardial infarction heart failure. Cardiovasc Diabetol. 2011 ; 10: 85
-
(2011)
Cardiovasc Diabetol
, vol.10
, pp. 85
-
-
Yin, M.1
Sillje, H.H.2
Meissner, M.3
-
53
-
-
77951934948
-
DPP-4 inhibition by sitagliptin improves the myocardial response to dobutamine stress and mitigates stunning in a pilot study of patients with coronary artery disease
-
Read PA, Khan FZ, Heck PM, et al. DPP-4 inhibition by sitagliptin improves the myocardial response to dobutamine stress and mitigates stunning in a pilot study of patients with coronary artery disease. Circ Cardiovasc Imaging. 2010 ; 3: 195-201
-
(2010)
Circ Cardiovasc Imaging
, vol.3
, pp. 195-201
-
-
Read, P.A.1
Khan, F.Z.2
Heck, P.M.3
-
54
-
-
84867184529
-
Dipeptidyl peptidase 4 inhibition increases myocardial glucose uptake in nonischemic cardiomyopathy
-
Witteles RM, Keu KV, Quon A, et al. Dipeptidyl peptidase 4 inhibition increases myocardial glucose uptake in nonischemic cardiomyopathy. J Card Fail. 2012 ; 18: 804-809
-
(2012)
J Card Fail
, vol.18
, pp. 804-809
-
-
Witteles, R.M.1
Keu, K.V.2
Quon, A.3
-
55
-
-
84883765959
-
Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus
-
Scirica BM, Bhatt DL, Braunwald E, et al. Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus. N Engl J Med. 2013 ; 369: 1317-1326
-
(2013)
N Engl J Med
, vol.369
, pp. 1317-1326
-
-
Scirica, B.M.1
Bhatt, D.L.2
Braunwald, E.3
-
57
-
-
84888644874
-
Rationale, design, and organization of a randomized, controlled Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS) in patients with type 2 diabetes and established cardiovascular disease
-
Green JB, Bethel MA, Paul SK, et al. Rationale, design, and organization of a randomized, controlled Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS) in patients with type 2 diabetes and established cardiovascular disease. Am Heart J. 2013 ; 166: 983-989.e7
-
(2013)
Am Heart J
, vol.166
, pp. 983-989e7
-
-
Green, J.B.1
Bethel, M.A.2
Paul, S.K.3
-
58
-
-
84879324855
-
Cardiovascular outcome trials in type 2 diabetes and the sulphonylurea controversy: Rationale for the active-comparator CAROLINA trial
-
Rosenstock J, Marx N, Kahn SE, et al. Cardiovascular outcome trials in type 2 diabetes and the sulphonylurea controversy: rationale for the active-comparator CAROLINA trial. Diab Vasc Dis Res. 2013 ; 10: 289-301
-
(2013)
Diab Vasc Dis Res
, vol.10
, pp. 289-301
-
-
Rosenstock, J.1
Marx, N.2
Kahn, S.E.3
-
59
-
-
62949195390
-
Synergy between CD26/DPP-IV inhibition and G-CSF improves cardiac function after acute myocardial infarction
-
Zaruba MM, Theiss HD, Vallaster M, et al. Synergy between CD26/DPP-IV inhibition and G-CSF improves cardiac function after acute myocardial infarction. Cell Stem Cell. 2009 ; 4: 313-323
-
(2009)
Cell Stem Cell
, vol.4
, pp. 313-323
-
-
Zaruba, M.M.1
Theiss, H.D.2
Vallaster, M.3
-
60
-
-
20944436176
-
Circulating endothelial progenitor cells are reduced in peripheral vascular complications of type 2 diabetes mellitus
-
Fadini GP, Miorin M, Facco M, et al. Circulating endothelial progenitor cells are reduced in peripheral vascular complications of type 2 diabetes mellitus. J Am Coll Cardiol. 2005 ; 45: 1449-1457
-
(2005)
J Am Coll Cardiol
, vol.45
, pp. 1449-1457
-
-
Fadini, G.P.1
Miorin, M.2
Facco, M.3
-
61
-
-
0037180517
-
Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures
-
Tepper OM, Galiano RD, Capla JM, et al. Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures. Circulation. 2002 ; 106: 2781-2786
-
(2002)
Circulation
, vol.106
, pp. 2781-2786
-
-
Tepper, O.M.1
Galiano, R.D.2
Capla, J.M.3
-
62
-
-
8544258807
-
Effects of glucagon-like peptide-1 on endothelial function in type 2 diabetes patients with stable coronary artery disease
-
Nystrom T, Gutniak MK, Zhang Q, et al. Effects of glucagon-like peptide-1 on endothelial function in type 2 diabetes patients with stable coronary artery disease. Am J Physiol Endocrinol Metab. 2004 ; 287: E1209 - E1215
-
(2004)
Am J Physiol Endocrinol Metab
, vol.287
, pp. 1209-E1215
-
-
Nystrom, T.1
Gutniak, M.K.2
Zhang, Q.3
-
63
-
-
36148932551
-
Beneficial effects of GLP-1 on endothelial function in humans: Dampening by glyburide but not by glimepiride
-
Basu A, Charkoudian N, Schrage W, et al. Beneficial effects of GLP-1 on endothelial function in humans: dampening by glyburide but not by glimepiride. Am J Physiol Endocrinol Metab. 2007 ; 293: E1289 - E1295
-
(2007)
Am J Physiol Endocrinol Metab
, vol.293
, pp. 1289-E1295
-
-
Basu, A.1
Charkoudian, N.2
Schrage, W.3
-
64
-
-
84890536384
-
Effect of GLP-1 mimetics on blood pressure and relationship to weight loss and glycemia lowering: Results of a systematic meta-analysis and meta-regression
-
Katout M, Zhu H, Rutsky J, et al. Effect of GLP-1 mimetics on blood pressure and relationship to weight loss and glycemia lowering: results of a systematic meta-analysis and meta-regression. Am J Hypertens. 2014 ; 27: 130-139
-
(2014)
Am J Hypertens
, vol.27
, pp. 130-139
-
-
Katout, M.1
Zhu, H.2
Rutsky, J.3
-
65
-
-
84902281059
-
Substance P increases sympathetic activity during combined angiotensin-converting enzyme and dipeptidyl peptidase-4 inhibition
-
Devin JK, Pretorius M, Nian H, et al. Substance P increases sympathetic activity during combined angiotensin-converting enzyme and dipeptidyl peptidase-4 inhibition. Hypertension. 2014 ; 63: 951-957
-
(2014)
Hypertension
, vol.63
, pp. 951-957
-
-
Devin, J.K.1
Pretorius, M.2
Nian, H.3
-
66
-
-
58149094297
-
Safety and tolerability of sitagliptin in patients with type 2 diabetes: A pooled analysis
-
Williams-Herman D, Round E, Swern AS, et al. Safety and tolerability of sitagliptin in patients with type 2 diabetes: a pooled analysis. BMC Endocr Disord. 2008 ; 8: 14
-
(2008)
BMC Endocr Disord
, vol.8
, pp. 14
-
-
Williams-Herman, D.1
Round, E.2
Swern, A.S.3
-
67
-
-
77953108350
-
A systematic assessment of cardiovascular outcomes in the saxagliptin drug development program for type 2 diabetes
-
Frederich R, Alexander JH, Fiedorek FT, et al. A systematic assessment of cardiovascular outcomes in the saxagliptin drug development program for type 2 diabetes. Postgrad Med. 2010 ; 122: 16-27
-
(2010)
Postgrad Med
, vol.122
, pp. 16-27
-
-
Frederich, R.1
Alexander, J.H.2
Fiedorek, F.T.3
-
68
-
-
84855481995
-
Cardiovascular safety with linagliptin in patients with type 2 diabetes mellitus: A pre-specified, prospective, and adjudicated meta-analysis of a phase 3 programme
-
Johansen OE, Neubacher D, Von Eynatten M, et al. Cardiovascular safety with linagliptin in patients with type 2 diabetes mellitus: a pre-specified, prospective, and adjudicated meta-analysis of a phase 3 programme. Cardiovasc Diabetol. 2012 ; 11: 3
-
(2012)
Cardiovasc Diabetol
, vol.11
, pp. 3
-
-
Johansen, O.E.1
Neubacher, D.2
Von Eynatten, M.3
-
69
-
-
77953182696
-
Assessing the cardio-cerebrovascular safety of vildagliptin: Meta-analysis of adjudicated events from a large phase III type 2 diabetes population
-
Schweizer A, Dejager S, Foley JE, et al. Assessing the cardio-cerebrovascular safety of vildagliptin: meta-analysis of adjudicated events from a large phase III type 2 diabetes population. Diabetes Obes Metab. 2010 ; 12: 485-494
-
(2010)
Diabetes Obes Metab
, vol.12
, pp. 485-494
-
-
Schweizer, A.1
Dejager, S.2
Foley, J.E.3
-
70
-
-
84878939138
-
Cardiovascular safety of the dipetidyl peptidase-4 inhibitor alogliptin in type 2 diabetes mellitus
-
White WB, Pratley R, Fleck P, et al. Cardiovascular safety of the dipetidyl peptidase-4 inhibitor alogliptin in type 2 diabetes mellitus. Diabetes Obes Metab. 2013 ; 15: 668-673
-
(2013)
Diabetes Obes Metab
, vol.15
, pp. 668-673
-
-
White, W.B.1
Pratley, R.2
Fleck, P.3
-
71
-
-
79959796830
-
Impact of the U.S. Food and Drug Administration cardiovascular assessment requirements on the development of novel antidiabetes drugs
-
Hirshberg B, Raz I. Impact of the U.S. Food and Drug Administration cardiovascular assessment requirements on the development of novel antidiabetes drugs. Diabetes Care. 2011 ; 34: S101 - S106
-
(2011)
Diabetes Care
, vol.34
, pp. 101-S106
-
-
Hirshberg, B.1
Raz, I.2
-
72
-
-
84883745765
-
Alogliptin after acute coronary syndrome in patients with type 2 diabetes
-
White WB, Cannon CP, Heller SR, et al. Alogliptin after acute coronary syndrome in patients with type 2 diabetes. N Engl J Med. 2013 ; 369: 1327-1335
-
(2013)
N Engl J Med
, vol.369
, pp. 1327-1335
-
-
White, W.B.1
Cannon, C.P.2
Heller, S.R.3
-
73
-
-
84878185729
-
A critical analysis of the clinical use of incretin-based therapies: Are the GLP-1 therapies safe?
-
Butler PC, Elashoff M, Elashoff R, et al. A critical analysis of the clinical use of incretin-based therapies: are the GLP-1 therapies safe?. Diabetes Care. 2013 ; 36: 2118-2125
-
(2013)
Diabetes Care
, vol.36
, pp. 2118-2125
-
-
Butler, P.C.1
Elashoff, M.2
Elashoff, R.3
-
74
-
-
84879231610
-
A critical analysis of the clinical use of incretin-based therapies: The benefits by far outweigh the potential risks
-
Nauck MA. A critical analysis of the clinical use of incretin-based therapies: the benefits by far outweigh the potential risks. Diabetes Care. 2013 ; 36: 2126-2132
-
(2013)
Diabetes Care
, vol.36
, pp. 2126-2132
-
-
Nauck, M.A.1
-
75
-
-
84926477579
-
Cardiovascular outcomes with alogliptin in patients with type 2 diabetes mellitus and recent acute coronary syndromes
-
White WB. Cardiovascular outcomes with alogliptin in patients with type 2 diabetes mellitus and recent acute coronary syndromes. Presented at European Association for the Study of Diabetes ; Barcelona ;..
-
Presented at European Association for the Study of Diabetes
-
-
White, W.B.1
-
76
-
-
84891760955
-
Cardiovascular outcome studies with novel antidiabetes agents: Scientific and operational considerations
-
Hirshberg B, Katz A. Cardiovascular outcome studies with novel antidiabetes agents: scientific and operational considerations. Diabetes Care. 2013 ; 36: S253 - S258
-
(2013)
Diabetes Care
, vol.36
, pp. 253-S258
-
-
Hirshberg, B.1
Katz, A.2
-
77
-
-
71049118192
-
Intensive glucose-lowering therapy reduces cardiovascular disease events in veterans affairs diabetes trial participants with lower calcified coronary atherosclerosis
-
Reaven PD, Moritz TE, Schwenke DC, et al. Intensive glucose-lowering therapy reduces cardiovascular disease events in veterans affairs diabetes trial participants with lower calcified coronary atherosclerosis. Diabetes. 2009 ; 58: 2642-2648
-
(2009)
Diabetes
, vol.58
, pp. 2642-2648
-
-
Reaven, P.D.1
Moritz, T.E.2
Schwenke, D.C.3
-
78
-
-
45149131667
-
Effects of intensive glucose lowering in type 2 diabetes
-
Gerstein HC, Miller ME, Byington RP, et al. Effects of intensive glucose lowering in type 2 diabetes. N Engl J Med. 2008 ; 358: 2545-2559
-
(2008)
N Engl J Med
, vol.358
, pp. 2545-2559
-
-
Gerstein, H.C.1
Miller, M.E.2
Byington, R.P.3
-
79
-
-
84901926135
-
Dipeptidyl peptidase-4 inhibitors and heart failure: A meta-analysis of randomized clinical trials
-
Monami M, Dicembrini I, Mannucci E. Dipeptidyl peptidase-4 inhibitors and heart failure: a meta-analysis of randomized clinical trials. Nutr Metab Cardiovasc Dis. 2014 ; 24: 689-697
-
(2014)
Nutr Metab Cardiovasc Dis
, vol.24
, pp. 689-697
-
-
Monami, M.1
Dicembrini, I.2
Mannucci, E.3
-
80
-
-
84904007147
-
Dipeptidyl peptidase-4 inhibitors and cardiovascular outcomes: Meta-analysis of randomized clinical trials with 55,141 participants
-
Wu S, Hopper I, Skiba M, et al. Dipeptidyl peptidase-4 inhibitors and cardiovascular outcomes: meta-analysis of randomized clinical trials with 55,141 participants. Cardiovasc Ther. 2014 ; 32: 147-158
-
(2014)
Cardiovasc Ther
, vol.32
, pp. 147-158
-
-
Wu, S.1
Hopper, I.2
Skiba, M.3
|