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Volumn 63, Issue 5, 2014, Pages 951-957

Substance P increases sympathetic activity during combined angiotensin-converting enzyme and dipeptidyl peptidase-4 inhibition

Author keywords

Diabetes mellitus; Dipeptidyl peptidase 4; Hypertension; Norepinephrine; Renin angiotensin system; Vasodilation

Indexed keywords

AMINOPEPTIDASE P; BRADYKININ; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL PEPTIDASE IV; ENALAPRILAT; FIBRINOLYTIC AGENT; NORADRENALIN; PLACEBO; SITAGLIPTIN; SUBSTANCE P; TISSUE PLASMINOGEN ACTIVATOR; VASODILATOR AGENT;

EID: 84902281059     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.113.02767     Document Type: Article
Times cited : (57)

References (51)
  • 1
    • 84872424922 scopus 로고    scopus 로고
    • An emerging role of dipeptidyl peptidase 4 (DPP4) beyond glucose control: Potential implications in cardiovascular disease
    • Zhong J, Rao X, Rajagopalan S. An emerging role of dipeptidyl peptidase 4 (DPP4) beyond glucose control: potential implications in cardiovascular disease. Atherosclerosis. 2013; 226: 305-314.
    • (2013) Atherosclerosis , vol.226 , pp. 305-314
    • Zhong, J.1    Rao, X.2    Rajagopalan, S.3
  • 2
    • 34247269160 scopus 로고    scopus 로고
    • Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: Focus on sitagliptin
    • DOI 10.1038/sj.clpt.6100167, PII 6100167
    • Herman GA, Stein PP, Thornberry N.A., Wagner JA Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: focus on sitagliptin. Clin Pharmacol Ther. 2007; 81: 761-767. (Pubitemid 46625120)
    • (2007) Clinical Pharmacology and Therapeutics , vol.81 , Issue.5 , pp. 761-767
    • Herman, G.A.1    Stein, P.P.2    Thornberry, N.A.3    Wagner, J.A.4
  • 3
    • 80051795160 scopus 로고    scopus 로고
    • Cardiovascular effects of DPP-4 inhibition: Beyond GLP-1
    • Fadini GP, Avogaro A. Cardiovascular effects of DPP-4 inhibition: beyond GLP-1. Vascul Pharmacol. 2011; 55: 10-16.
    • (2011) Vascul Pharmacol , vol.55 , pp. 10-16
    • Fadini, G.P.1    Avogaro, A.2
  • 4
    • 0025341208 scopus 로고
    • The effect of local converting enzyme inhibition on the dilator response to substance P in the human forearm
    • Benjamin N, Webb DJ The effect of local converting enzyme inhibition on the dilator response to substance P in the human forearm. Br J Clin Pharmacol. 1990; 29: 774-776. (Pubitemid 20183680)
    • (1990) British Journal of Clinical Pharmacology , vol.29 , Issue.6 , pp. 774-776
    • Benjamin, N.1    Webb, D.J.2
  • 5
    • 0026755628 scopus 로고
    • Dipeptidyl(amino)peptidase IV and amino-peptidase M metabolize circulating substance P in vivo
    • Ahmad S, Wang L, Ward PE Dipeptidyl(amino)peptidase IV and amino-peptidase M metabolize circulating substance P in vivo. J Pharmacol Exp Ther. 1992; 260: 1257-1261.
    • (1992) J Pharmacol Exp Ther , vol.260 , pp. 1257-1261
    • Ahmad, S.1    Wang, L.2    Ward, P.E.3
  • 7
    • 0033048762 scopus 로고    scopus 로고
    • Bradykinin stimulates tissue plasminogen activator release in human vasculature
    • Brown NJ, Gainer JV, Stein C.M., Vaughan DE Bradykinin stimulates tissue plasminogen activator release in human vasculature. Hypertension. 1999; 33: 1431-1435. (Pubitemid 29282666)
    • (1999) Hypertension , vol.33 , Issue.6 , pp. 1431-1435
    • Brown, N.J.1    Gainer, J.V.2    Stein, C.M.3    Vaughan, D.E.4
  • 8
    • 33644814714 scopus 로고    scopus 로고
    • Stimulated tissue plasminogen activator release as a marker of endothelial function in humans
    • DOI 10.1161/01.ATV.0000189309.05924.88, PII 0004360520051200000006
    • Oliver JJ, Webb DJ, Newby DE Stimulated tissue plasminogen activator release as a marker of endothelial function in humans. Arterioscler Thromb Vasc Biol. 2005; 25: 2470-2479. (Pubitemid 43732266)
    • (2005) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.25 , Issue.12 , pp. 2470-2479
    • Oliver, J.J.1    Webb, D.J.2    Newby, D.E.3
  • 9
    • 34447536751 scopus 로고    scopus 로고
    • Endogenous substance P modulates human cardiovascular regulation at rest and during orthostatic load
    • DOI 10.1152/japplphysiol.00969.2006
    • Dzurik MV, Diedrich A, Black B., Paranjape SY, Raj SR, Byrne DW, Robertson D. Endogenous substance P modulates human cardiovascular regulation at rest and during orthostatic load. J Appl Physiol (1985). 2007; 102: 2092-2097. (Pubitemid 47080738)
    • (2007) Journal of Applied Physiology , vol.102 , Issue.6 , pp. 2092-2097
    • Dzurik, M.V.1    Diedrich, A.2    Black, B.3    Paranjape, S.Y.4    Raj, S.R.5    Byrne, D.W.6    Robertson, D.7
  • 10
    • 0028827211 scopus 로고
    • Pressor and tachycardic responses to intravenous substance P in anesthetized rats
    • Hancock JC, Lindsay GW Pressor and tachycardic responses to intravenous substance P in anesthetized rats. Peptides. 1995; 16: 1439-1445.
    • (1995) Peptides , vol.16 , pp. 1439-1445
    • Hancock, J.C.1    Lindsay, G.W.2
  • 11
    • 0034060107 scopus 로고    scopus 로고
    • Enhanced ganglionic responses to substance P in spontaneously hypertensive rats
    • DOI 10.1016/S0196-9781(00)00170-4, PII S0196978100001704
    • Hancock JC, Lindsay GW Enhanced ganglionic responses to substance P in spontaneously hypertensive rats. Peptides. 2000; 21: 535-541. (Pubitemid 30261571)
    • (2000) Peptides , vol.21 , Issue.4 , pp. 535-541
    • Hancock, J.C.1    Lindsay, G.W.2
  • 12
    • 0034688194 scopus 로고    scopus 로고
    • Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The heart outcomes prevention evaluation study investigators
    • Yusuf S, Sleight P, Pogue J., Bosch J, Davies R, Dagenais G. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med. 2000; 342: 145-153.
    • (2000) N Engl J Med. , vol.342 , pp. 145-153
    • Yusuf, S.1    Sleight, P.2    Pogue, J.3    Bosch, J.4    Davies, R.5    Dagenais, G.6
  • 13
    • 27644579447 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibition increases basal vascular tissue plasminogen activator release in women but not in men
    • DOI 10.1161/01.ATV.0000186185.13977.94
    • Pretorius M, Luther JM, Murphey L.J., Vaughan DE, Brown NJ Angiotensin-converting enzyme inhibition increases basal vascular tissue plasminogen activator release in women but not in men. Arterioscler Thromb Vasc Biol. 2005; 25: 2435-2440. (Pubitemid 41552667)
    • (2005) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.25 , Issue.11 , pp. 2435-2440
    • Pretorius, M.1    Luther, J.M.2    Murphey, L.J.3    Vaughan, D.E.4    Brown, N.J.5
  • 14
    • 77957231074 scopus 로고    scopus 로고
    • Interactive hemodynamic effects of dipeptidyl peptidase-IV inhibition and angiotensin-converting enzyme inhibition in humans
    • Marney A, Kunchakarra S, Byrne L., Brown NJ Interactive hemodynamic effects of dipeptidyl peptidase-IV inhibition and angiotensin-converting enzyme inhibition in humans. Hypertension. 2010; 56: 728-733.
    • (2010) Hypertension , vol.56 , pp. 728-733
    • Marney, A.1    Kunchakarra, S.2    Byrne, L.3    Brown, N.J.4
  • 17
    • 23844446798 scopus 로고    scopus 로고
    • Energy expenditure by intravenous administration of glucagon-like peptide-1 mediated by the lower brainstem and sympathoadrenal system
    • DOI 10.1016/j.peptides.2005.02.016, PII S0196978105000690
    • Osaka T, Endo M, Yamakawa M., Inoue S. Energy expenditure by intravenous administration of glucagon-like peptide-1 mediated by the lower brainstem and sympathoadrenal system. Peptides. 2005; 26: 1623-1631. (Pubitemid 41169757)
    • (2005) Peptides , vol.26 , Issue.9 , pp. 1623-1631
    • Osaka, T.1    Endo, M.2    Yamakawa, M.3    Inoue, S.4
  • 20
    • 0022573623 scopus 로고
    • Capsaicin induces a depletion of calcitonin gene-related peptide (CGRP)-immunoreactive nerves in the cardiovascular system of the guinea pig and rat
    • DOI 10.1016/0165-1838(86)90035-4
    • Wharton J, Gulbenkian S, Mulderry P.K., Ghatei MA, McGregor GP, Bloom SR, Polak JM Capsaicin induces a depletion of calcitonin gene-related peptide (CGRP)-immunoreactive nerves in the cardiovascular system of the guinea pig and rat. J Auton Nerv Syst. 1986; 16: 289-309. (Pubitemid 16090542)
    • (1986) Journal of the Autonomic Nervous System , vol.16 , Issue.4 , pp. 289-309
    • Wharton, J.1    Gulbenkian, S.2    Mulderry, P.K.3
  • 22
    • 0024827138 scopus 로고
    • Noradrenergic and peptidergic innervation of the extrinsic vessels and microcirculation of the rat cremaster muscle
    • DOI 10.1016/0026-2862(89)90004-6
    • Fleming BP, Gibbins IL, Morris J.L., Gannon BJ Noradrenergic and pep-tidergic innervation of the extrinsic vessels and microcirculation of the rat cremaster muscle. Microvasc Res. 1989; 38: 255-268. (Pubitemid 20025049)
    • (1989) Microvascular Research , vol.38 , Issue.3 , pp. 255-268
    • Fleming, B.P.1    Gibbins, I.L.2    Morris, J.L.3    Gannon, B.J.4
  • 25
    • 0030901851 scopus 로고    scopus 로고
    • Substance P and epibatidine-evoked catecholamine release from fractionated chromaffin cells
    • DOI 10.1016/S0014-2999(97)83052-X, PII S001429999700112X
    • Krause W, Michael N, Lübke C, Livett B.G., Oehme P. Substance P and epibatidine-evoked catecholamine release from fractionated chromaffin cells. Eur J Pharmacol. 1997; 328: 249-254. (Pubitemid 27263364)
    • (1997) European Journal of Pharmacology , vol.328 , Issue.2-3 , pp. 249-254
    • Krause, W.1    Michael, N.2    Lubke, C.3    Livett, B.G.4    Oehme, P.5
  • 26
    • 83455261818 scopus 로고    scopus 로고
    • Targeting cardiac mast cells: Pharmacological modulation of the local renin-angiotensin system
    • Reid AC, Brazin JA, Morrey C, Silver R.B., Levi R. Targeting cardiac mast cells: pharmacological modulation of the local renin-angiotensin system. Curr Pharm Des. 2011; 17: 3744-3752.
    • (2011) Curr Pharm Des , vol.17 , pp. 3744-3752
    • Reid, A.C.1    Brazin, J.A.2    Morrey, C.3    Silver, R.B.4    Levi, R.5
  • 27
    • 0021930258 scopus 로고
    • Tissue plasminogen activator release in vivo in response to vasoactive agents
    • Smith D, Gilbert M, Owen WG Tissue plasminogen activator release in vivo in response to vasoactive agents. Blood. 1985; 66: 835-839. (Pubitemid 15242467)
    • (1985) Blood , vol.66 , Issue.4 , pp. 835-839
    • Smith, D.1    Gilbert, M.2    Owen, W.G.3
  • 28
    • 0033596924 scopus 로고    scopus 로고
    • Endothelial dysfunction, impaired endogenous fibrinolysis, and cigarette smoking: A mechanism for arterial thrombosis and myocardial infarction
    • Newby DE, Wright RA, Labinjoh C, Ludlam C.A., Fox KA, Boon NA, Webb DJ Endothelial dysfunction, impaired endogenous fibrinolysis, and cigarette smoking: a mechanism for arterial thrombosis and myocardial infarction. Circulation. 1999; 99: 1411-1415. (Pubitemid 29140904)
    • (1999) Circulation , vol.99 , Issue.11 , pp. 1411-1415
    • Newby, D.E.1    Wright, R.A.2    Labinjoh, C.3    Ludlam, C.A.4    Fox, K.A.A.5    Boon, N.A.6    Webb, D.J.7
  • 29
    • 0035499032 scopus 로고    scopus 로고
    • Potentiation of bradykinin-induced tissue plasminogen activator release by angiotensin-converting enzyme inhibition
    • DOI 10.1016/S0735-1097(01)01562-5, PII S0735109701015625
    • Labinjoh C, Newby DE, Pellegrini M.P., Johnston NR, Boon NA, Webb DJ Potentiation of bradykinin-induced tissue plasminogen activator release by angiotensin-converting enzyme inhibition. J Am Coll Cardiol. 2001; 38: 1402-1408. (Pubitemid 33033018)
    • (2001) Journal of the American College of Cardiology , vol.38 , Issue.5 , pp. 1402-1408
    • Labinjoh, C.1    Newby, D.E.2    Pellegrini, M.P.3    Johnston, N.R.4    Boon, N.A.5    Webb, D.J.6
  • 30
    • 0022364678 scopus 로고
    • Hydrolysis of substance P and its analogs by angiotensin-converting enzyme from rat lung. Characterization of endopeptidase activity of the enzyme
    • Yokosawa H, Endo S, Ohgaki Y., Maeyama J, Ishii S. Hydrolysis of substance P and its analogs by angiotensin-converting enzyme from rat lung. Characterization of endopeptidase activity of the enzyme. J Biochem. 1985; 98: 1293-1299. (Pubitemid 16199239)
    • (1985) Journal of Biochemistry , vol.98 , Issue.5 , pp. 1293-1299
    • Yokosawa, H.1    Endo, S.2    Ohgaki, Y.3
  • 31
    • 0026326713 scopus 로고
    • Differential processing of substance P and neurokinin A by plasma dipeptidyl(amino) peptidase IV, aminopeptidase M and angiotensin converting enzyme
    • Wang LH, Ahmad S, Benter I.F., Chow A., Mizutani S, Ward PE Differential processing of substance P and neurokinin A by plasma dipeptidyl(amino) peptidase IV, aminopeptidase M and angiotensin converting enzyme. Peptides. 1991; 12: 1357-1364.
    • (1991) Peptides , vol.12 , pp. 1357-1364
    • Wang, L.H.1    Ahmad, S.2    Benter, I.F.3    Chow, A.4    Mizutani, S.5    Ward, P.E.6
  • 32
    • 0026280591 scopus 로고
    • Axon reflex vasodilatation in human skin measured by a laser doppler technique
    • Izumi H, Karita K. Axon reflex vasodilatation in human skin measured by a laser Doppler technique. Jpn J Physiol. 1991; 41: 693-702.
    • (1991) Jpn J Physiol , vol.41 , pp. 693-702
    • Izumi, H.1    Karita, K.2
  • 33
    • 27844573849 scopus 로고    scopus 로고
    • Neurokinin-1 receptor desensitization to consecutive microdialysis infusions of substance P in human skin
    • DOI 10.1113/jphysiol.2005.095372
    • Wong BJ, Tublitz NJ, Minson CT Neurokinin-1 receptor desensitization to consecutive microdialysis infusions of substance P in human skin. J Physiol. 2005; 568(Pt 3): 1047-1056. (Pubitemid 41646041)
    • (2005) Journal of Physiology , vol.568 , Issue.3 , pp. 1047-1056
    • Wong, B.J.1    Tublitz, N.J.2    Minson, C.T.3
  • 34
    • 0023929623 scopus 로고
    • Vasodilatation by calcitonin gene-related peptide and by substance P: A comparison of their effects on resistance and capacitance vessels of human forearms
    • McEwan Jr, Benjamin N, Larkin S., Fuller RW, Dollery CT, MacIntyre I. Vasodilatation by calcitonin gene-related peptide and by substance P: a comparison of their effects on resistance and capacitance vessels of human forearms. Circulation. 1988; 77: 1072-1080.
    • (1988) Circulation , vol.77 , pp. 1072-1080
    • McEwan, J.R.1    Benjamin, N.2    Larkin, S.3    Fuller, R.W.4    Dollery, C.T.5    MacIntyre, I.6
  • 36
    • 0026548038 scopus 로고
    • Substance P provokes cutaneous erythema and edema through a histamine-independent pathway
    • Cappugi P, Tsampau D, Lotti T. Substance P provokes cutaneous erythema and edema through a histamine-independent pathway. Int J Dermatol. 1992; 31: 206-209.
    • (1992) Int J Dermatol , vol.31 , pp. 206-209
    • Cappugi, P.1    Tsampau, D.2    Lotti, T.3
  • 37
    • 0027223996 scopus 로고
    • Neuropeptides induce rapid expression of endothelial cell adhesion molecules and elicit granulocytic infiltration in human skin
    • Smith CH, Barker JN, Morris R.W., MacDonald DM, Lee TH Neuropeptides induce rapid expression of endothelial cell adhesion molecules and elicit granulocytic infiltration in human skin. J Immunol. 1993; 151: 3274-3282. (Pubitemid 23282640)
    • (1993) Journal of Immunology , vol.151 , Issue.6 , pp. 3274-3282
    • Smith, C.H.1    Barker, J.N.W.N.2    Morris, R.W.3    MacDonald, D.M.4    Lee, T.H.5
  • 38
    • 79955952000 scopus 로고    scopus 로고
    • Sitagliptin, a dipeptidyl peptidase-4 inhibitor, decreases systolic blood pressure in Japanese hypertensive patients with type 2 diabetes
    • Ogawa S, Ishiki M, Nako K., Okamura M, Senda M, Mori T., Ito S. Sitagliptin, a dipeptidyl peptidase-4 inhibitor, decreases systolic blood pressure in Japanese hypertensive patients with type 2 diabetes. Tohoku J Exp Med. 2011; 223: 133-135.
    • (2011) Tohoku J Exp Med. , vol.223 , pp. 133-135
    • Ogawa, S.1    Ishiki, M.2    Nako, K.3    Okamura, M.4    Senda, M.5    Mori, T.6    Ito, S.7
  • 39
    • 34147093268 scopus 로고    scopus 로고
    • Effects of vildagliptin on glucose control over 24 weeks in patients with type 2 diabetes inadequately controlled with metformin
    • DOI 10.2337/dc06-1732
    • Bosi E, Camisasca RP, Collober C, Rochotte E., Garber AJ Effects of vilda-gliptin on glucose control over 24 weeks in patients with type 2 diabetes inadequately controlled with metformin. Diabetes Care. 2007; 30: 890-895. (Pubitemid 46556583)
    • (2007) Diabetes Care , vol.30 , Issue.4 , pp. 890-895
    • Bosi, E.1    Camisasca, R.P.2    Collober, C.3    Rochotte, E.4    Garber, A.J.5
  • 41
    • 84870053428 scopus 로고    scopus 로고
    • Dipeptidyl peptidase-4 inhibition with saxagliptin enhanced nitric oxide release and reduced blood pressure and sICAM-1 levels in hypertensive rats
    • Mason RP, Jacob RF, Kubant R, Ciszewski A., Corbalan JJ, Malinski T. Dipeptidyl peptidase-4 inhibition with saxagliptin enhanced nitric oxide release and reduced blood pressure and sICAM-1 levels in hypertensive rats. J Cardiovasc Pharmacol. 2012; 60: 467-473.
    • (2012) J Cardiovasc Pharmacol , vol.60 , pp. 467-473
    • Mason, R.P.1    Jacob, R.F.2    Kubant, R.3    Ciszewski, A.4    Corbalan, J.J.5    Malinski, T.6
  • 43
    • 83455230038 scopus 로고    scopus 로고
    • Vildagliptin improves endothelium-dependent vasodilatation in type 2 diabetes
    • van Poppel P.C., Netea MG, Smits P, Tack CJ Vildagliptin improves endothelium-dependent vasodilatation in type 2 diabetes. Diabetes Care. 2011; 34: 2072-2077.
    • (2011) Diabetes Care , vol.34 , pp. 2072-2077
    • Van Poppel, P.C.1    Netea, M.G.2    Smits, P.3    Tack, C.J.4
  • 46
    • 84883765959 scopus 로고    scopus 로고
    • Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus
    • SAVOR-TIMI 53 Steering Committee and Investigators
    • Scirica BM, Bhatt DL, Braunwald E, et al.; SAVOR-TIMI 53 Steering Committee and Investigators. Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus. N Engl J Med. 2013; 369: 1317-1326.
    • (2013) N Engl J Med. , vol.369 , pp. 1317-1326
    • Scirica, B.M.1    Bhatt, D.L.2    Braunwald, E.3
  • 47
    • 84880682777 scopus 로고
    • Congestive heart failure. Biochemical and physiological considerations. Combined clinical staff conference at the national institutes of health
    • Braunwald E, Chidsey CA, Pool P.E., Sonnenblick EH, Ross J Jr, Mason DT, Spann JF, Covell JW. Congestive heart failure. Biochemical and physiological considerations. Combined clinical staff conference at the National Institutes of Health. Ann Intern Med. 1966; 64: 904-941.
    • (1966) Ann Intern Med. , vol.64 , pp. 904-941
    • Braunwald, E.1    Chidsey, C.A.2    Pool, P.E.3    Sonnenblick, E.H.4    Ross Jr., J.5    Mason, D.T.6    Spann, J.F.7    Covell, J.W.8
  • 48
    • 0013892040 scopus 로고
    • Sympathetic activity and neurotransmitter depletion in congestive heart failure
    • Chidsey CA, Braunwald E. Sympathetic activity and neurotransmitter depletion in congestive heart failure. Pharmacol Rev. 1966; 18: 685-700.
    • (1966) Pharmacol Rev , vol.18 , pp. 685-700
    • Chidsey, C.A.1    Braunwald, E.2
  • 50
    • 84863287243 scopus 로고    scopus 로고
    • Serum levels of calcitonin gene-related peptide and substance P are decreased in patients with diabetes mellitus and coronary artery disease
    • Wang LH, Zhou SX, Li R.C., Zheng LR, Zhu JH, Hu SJ, Sun YL Serum levels of calcitonin gene-related peptide and substance P are decreased in patients with diabetes mellitus and coronary artery disease. J Int Med Res. 2012; 40: 134-140.
    • (2012) J Int Med Res , vol.40 , pp. 134-140
    • Wang, L.H.1    Zhou, S.X.2    Li, R.C.3    Zheng, L.R.4    Zhu, J.H.5    Hu, S.J.6    Sun, Y.L.7
  • 51
    • 79952370968 scopus 로고    scopus 로고
    • Substance P is associated with the development of obesity, chronic inflammation and type 2 diabetes mellitus
    • Fu J, Liu B, Liu P., Liu L, Li G, Wu B., Liu X. Substance P is associated with the development of obesity, chronic inflammation and type 2 diabetes mellitus. Exp Clin Endocrinol Diabetes. 2011; 119: 177-181.
    • (2011) Exp Clin Endocrinol Diabetes , vol.119 , pp. 177-181
    • Fu, J.1    Liu, B.2    Liu, P.3    Liu, L.4    Li, G.5    Wu, B.6    Liu, X.7


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