Lack of agreement for defining 'clinical suspicion of rejection' in liver transplantation: A model to select candidates for liver biopsy

Transplant International

Volumn 28, Issue 4, 2015, Pages 455-464

  Rodríguez Perálvarez, Manuel ^a   García Caparrõs, Carmen ^a   Tsochatzis, Emmanuel ^b   Germani, Giacomo ^b,c   Hogan, Brian ^b   Poyato González, Antonio ^a   O'Beirne, James ^b   Senzolo, Marco ^c   Guerrero Misas, Marta ^a   Montero Álvarez, Jose L ^a   Patch, David ^b   Barrera, Pilar ^a   Briceño, Javier ^a   Dhillon, Amar P ^b   Burra, Patrizia ^c   Burroughs, Andrew K ^b   De La Mata, Manuel ^a  

^a HOSPITAL UNIVERSITARIO REINA SOFÍA   (Spain)

^b ROYAL FREE HOSPITAL   (United Kingdom)

^c UNIVERSITY HOSPITAL OF PADOVA   (Italy)

Author keywords

acute cellular rejection; biopsy; concordance; diagnosis; liver transplantation

Indexed keywords

TACROLIMUS;

ACUTE GRAFT REJECTION; ADULT; ARTICLE; EOSINOPHIL; FEMALE; HISTOLOGY; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; LABORATORY TEST; LIVER BIOPSY; LIVER FUNCTION TEST; LIVER GRAFT REJECTION; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; BIOPSY; GRAFT REJECTION; LIVER; MIDDLE AGED; MULTIVARIATE ANALYSIS; PATHOLOGY; PATIENT SELECTION; STATISTICAL MODEL; STATISTICS AND NUMERICAL DATA;

ADULT; BIOPSY; FEMALE; GRAFT REJECTION; HUMANS; LIVER; LIVER TRANSPLANTATION; LOGISTIC MODELS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PATIENT SELECTION;

EID: 84926419434     PISSN: 09340874     EISSN: 14322277     Source Type: Journal    
DOI: 10.1111/tri.12514     Document Type: Article

References (29)

1. Shaked A, Ghobrial RM, Merion RM, et al,. Incidence and severity of acute cellular rejection in recipients undergoing adult living donor or deceased donor liver transplantation. Am J Transplant 2009; 9: 301.
2. Lerut J, Mathys J, Verbaandert C, et al,. Tacrolimus monotherapy in liver transplantation: one-year results of a prospective, randomized, double-blind, placebo-controlled study. Ann Surg 2008; 248: 956.
3. Boillot O, Seket B, Dumortier J, et al,. Thymoglobulin induction in liver transplant recipients with a tacrolimus, mycophenolate mofetil, and steroid immunosuppressive regimen: a five-year randomized prospective study. Liver Transpl 2009; 15: 1426.
4. Wiesner RH, Ludwig J, Krom RA, et al,. Treatment of early cellular rejection following liver transplantation with intravenous methylprednisolone. The effect of dose on response. Transplantation 1994; 58: 1053.
5. Thurairajah PH, Carbone M, Bridgestock H, et al,. Late acute liver allograft rejection; a study of its natural history and graft survival in the current era. Transplantation 2013; 95: 955.
6. Burroughs AK, Patch DW, Stigliano R, Cecilioni L,. Protocol biopsies in liver transplantation. Liver Transpl 2003; 9: 780.
7. Rodriguez-Peralvarez M, Germani G, Tsochatzis E, et al,. Predicting severity and clinical course of acute rejection after liver transplantation using blood eosinophil count. Transpl Int 2012; 25: 555.
8. Demetris A, Batts K, Dhillon A, et al,. Banff schema for grading liver allograft rejection: an international consensus document. Hepatology 1997; 25: 658.
9. Wiesner RH, Demetris AJ, Belle SH, et al,. Acute hepatic allograft rejection: incidence, risk factors, and impact on outcome. Hepatology 1998; 28: 638.
10. Peduzzi P, Concato J, Kemper E, Holford TR, Feinstein AR,. A simulation study of the number of events per variable in logistic regression analysis. J Clin Epidemiol 1996; 49: 1373.
11. Adam R, Karam V, Delvart V, et al,. Evolution of indications and results of liver transplantation in Europe. A report from the European Liver Transplant Registry (ELTR). J Hepatol 2012; 57: 675.
12. Bartlett AS, Ramadas R, Furness S, Gane E, McCall JL,. The natural history of acute histologic rejection without biochemical graft dysfunction in orthotopic liver transplantation: a systematic review. Liver Transpl 2002; 8: 1147.
13. Rodriguez-Peralvarez M, Germani G, Papastergiou V, et al,. Early tacrolimus exposure after liver transplantation: relationship with moderate/severe acute rejection and long-term outcome. J Hepatol 2013; 58: 262.
14. Schlitt HJ, Nashan B, Krick P, et al,. Intragraft immune events after human liver transplantation. Correlation with clinical signs of acute rejection and influence of immunosuppression. Transplantation 1992; 54: 273.
15. Nagral A, Butler P, Sabin CA, Rolles K, Burroughs AK,. Alpha-glutathione-S-transferase in acute rejection of liver transplant recipients. Transplantation 1998; 65: 401.
16. Rodriguez-Peralvarez M, Germani G, Darius T, Lerut J, Tsochatzis E, Burroughs AK,. Tacrolimus trough levels, rejection and renal impairment in liver transplantation: a systematic review and meta-analysis. Am J Transplant 2012; 12: 2797.
17. Klintmalm GB, Washburn WK, Rudich SM, et al,. Corticosteroid-free immunosuppression with daclizumab in HCV(+) liver transplant recipients: 1-year interim results of the HCV-3 study. Liver Transpl 2007; 13: 1521.
18. Kato T, Gaynor JJ, Yoshida H, et al,. Randomized trial of steroid-free induction versus corticosteroid maintenance among orthotopic liver transplant recipients with hepatitis C virus: impact on hepatic fibrosis progression at one year. Transplantation 2007; 84: 829.
19. Neuberger JM, Mamelok RD, Neuhaus P, et al,. Delayed introduction of reduced-dose tacrolimus, and renal function in liver transplantation: the 'ReSpECT' study. Am J Transplant 2009; 9: 327.
20. Klintmalm GB, Feng S, Lake JR, et al,. Belatacept-based immunosuppression in de novo liver transplant recipients: 1-year experience from a phase II randomized study. Am J Transplant 2014; 14: 1817.
21. Ikegami T, Bekki Y, Imai D, et al,. Clinical outcomes of living donor liver transplantation for patients 65 years old or older with preserved performance status. Liver Transpl 2014; 20: 408.
22. Heinbokel T, Hock K, Liu G, Edtinger K, Elkhal A, Tullius SG,. Impact of immunosenescence on transplant outcome. Transpl Int 2013; 26: 242.
23. Boudjema K, Camus C, Saliba F, et al,. Reduced-dose tacrolimus with mycophenolate mofetil vs. standard-dose tacrolimus in liver transplantation: a randomized study. Am J Transplant 2011; 11: 965.
24. Saliba F, De Simone P, Nevens F, et al,. Renal function at two years in liver transplant patients receiving everolimus: results of a randomized, multicenter study. Am J Transplant 2013; 13: 1734.
25. Turner AP, Knechtle SJ,. Induction immunosuppression in liver transplantation: a review. Transpl Int 2013; 26: 673.
26. Barnes EJ, Abdel-Rehim MM, Goulis Y, et al,. Applications and limitations of blood eosinophilia for the diagnosis of acute cellular rejection in liver transplantation. Am J Transplant 2003; 3: 432.
27. Sanchez-Fueyo A, Strom TB,. Immunologic basis of graft rejection and tolerance following transplantation of liver or other solid organs. Gastroenterology 2011; 140: 51.
28. McCaughan GW, Zekry A,. Mechanisms of HCV reinfection and allograft damage after liver transplantation. J Hepatol 2004; 40: 368.
29. Berenguer M,. What determines the natural history of recurrent hepatitis C after liver transplantation? J Hepatol 2005; 42: 448.