Predicting severity and clinical course of acute rejection after liver transplantation using blood eosinophil count

Transplant International

Volumn 25, Issue 5, 2012, Pages 555-563

  Rodríguez Perálvarez, Manuel ^a   Germani, Giacomo ^a   Tsochatzis, Emmanuel ^a   Rolando, Nancy ^a   Luong, Tu Vinh ^a   Dhillon, Amar Paul ^a   Thorburn, Douglas ^a   O'Beirne, James ^a   Patch, David ^a   Burroughs, Andrew Kenneth ^a  

^a ROYAL FREE HOSPITAL   (United Kingdom)

Author keywords

acute cellular rejection; clinical course; eosinophil; liver transplantation; serum biomarker

Indexed keywords

AZATHIOPRINE; CYCLOSPORIN; METHYLPREDNISOLONE; PREDNISOLONE; TACROLIMUS;

ACUTE GRAFT REJECTION; ADD ON THERAPY; ADULT; ALCOHOL LIVER DISEASE; ARTICLE; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE SEVERITY; EOSINOPHIL COUNT; EOSINOPHILIA; FEMALE; HEPATITIS B; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOSUPPRESSIVE TREATMENT; LIVER BIOPSY; LIVER CELL CARCINOMA; LIVER FUNCTION TEST; LIVER GRAFT REJECTION; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; PREDICTION; PRIMARY BILIARY CIRRHOSIS; PRIMARY SCLEROSING CHOLANGITIS; PRIORITY JOURNAL; PROSPECTIVE STUDY;

ADRENAL CORTEX HORMONES; BIOPSY; EOSINOPHILIA; EOSINOPHILS; FEMALE; GRAFT REJECTION; HUMANS; LEUKEMIA, EOSINOPHILIC, ACUTE; LEUKOCYTE COUNT; LIVER TRANSPLANTATION; MALE; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROSPECTIVE STUDIES; TIME FACTORS;

EID: 84859705204     PISSN: 09340874     EISSN: 14322277     Source Type: Journal    
DOI: 10.1111/j.1432-2277.2012.01457.x     Document Type: Article

References (24)

1. Fisher LR, Henley KS, Lucey MR,. Acute cellular rejection after liver transplantation: variability, morbidity, and mortality. Liver Transpl Surg 1995; 1: 10.
2. Shaked A, Ghobrial RM, Merion RM, et al. Incidence and severity of acute cellular rejection in recipients undergoing adult living donor or deceased donor liver transplantation. Am J Transplant 2009; 9: 301.
3. Nagral A, Butler P, Sabin CA, Rolles K, Burroughs AK,. Alpha-glutathione-S-transferase in acute rejection of liver transplant recipients. Transplantation 1998; 65: 401.
4. Hughes VF, Trull AK, Joshi O, Alexander GJ,. Monitoring eosinophil activation and liver function after liver transplantation. Transplantation 1998; 65: 1334.
5. Burroughs AK, Patch DW, Stigliano R, Cecilioni L,. Protocol biopsies in liver transplantation. Liver Transpl 2003; 9: 780.
6. Kalambokis G, Manousou P, Vibhakorn S, et al. Transjugular liver biopsy-indications, adequacy, quality of specimens, and complications-a systematic review. J Hepatol 2007; 47: 284.
7. Neuberger J, Wilson P, Adams D,. Protocol liver biopsies: the case in favour. Transplant Proc 1998; 30: 1497.
8. Schlitt HJ, Nashan B, Krick P, et al. Intragraft immune events after human liver transplantation. Correlation with clinical signs of acute rejection and influence of immunosuppression. Transplantation 1992; 54: 273.
9. Weir MR, Hall-Craggs M, Shen SY, et al. The prognostic value of the eosinophil in acute renal allograft rejection. Transplantation 1986; 41: 709.
10. Trull A, Steel L, Cornelissen J, et al. Association between blood eosinophil counts and acute cardiac and pulmonary allograft rejection. J Heart Lung Transplant 1998; 17: 517.
11. Datta Gupta S, Hudson M, Burroughs AK, et al. Grading of cellular rejection after orthotopic liver transplantation. Hepatology 1995; 21: 46.
12. Nagral A, Quaglia A, Sabin CA, et al. Blood and graft eosinophils in acute cellular rejection of liver allografts. Transplant Proc 2001; 33: 2588.
13. Foster PF, Sankary HN, Hart M, Ashmann M, Williams JW,. Blood and graft eosinophilia as predictors of rejection in human liver transplantation. Transplantation 1989; 47: 72.
14. de Groen PC, Kephart GM, Gleich GJ, Ludwig J,. The eosinophil as an effector cell of the immune response during hepatic allograft rejection. Hepatology 1994; 20: 654.
15. Barnes EJ, Abdel-Rehim MM, Goulis Y, et al. Applications and limitations of blood eosinophilia for the diagnosis of acute cellular rejection in liver transplantation. Am J Transplant 2003; 3: 432.
16. Kishi Y, Sugawara Y, Tamura S, et al. Is blood eosinophilia an effective predictor of acute rejection in living donor liver transplantation? Transpl Int 2005; 18: 1147.
17. Bartlett AS, Ramadas R, Furness S, Gane E, McCall JL,. The natural history of acute histologic rejection without biochemical graft dysfunction in orthotopic liver transplantation: a systematic review. Liver Transpl 2002; 8: 1147.
18. Demetris AJ, Batts KP, Dhillon AP, et al. Banff schema for grading liver allograft rejection: an international consensus document. Hepatology 1997; 25: 658.
19. Rolles K, Davidson BR, Burroughs AK,. A pilot study of immunosuppressive monotherapy in liver transplantation: tacrolimus versus microemulsified cyclosporin. Transplantation 1999; 68: 1195.
20. O'Grady JG, Hardy P, Burroughs AK, Elbourne D,. Randomized controlled trial of tacrolimus versus microemulsified cyclosporin (TMC) in liver transplantation: poststudy surveillance to 3 years. Am J Transplant 2007; 7: 137.
21. Cholongitas E, Shusang V, Germani G, et al. Long-term follow-up of immunosuppressive monotherapy in liver transplantation: tacrolimus and microemulsified cyclosporin. Clin Transplant 2011; 25: 614.
22. Dickson RC, Lauwers GY, Rosen CB, Cantwell R, Nelson DR, Lau JY,. The utility of noninvasive serologic markers in the management of early allograft rejection in liver transplantation recipients. Transplantation 1999; 68: 247.
23. Trull AK, Facey SP, Rees GW, et al. Serum alpha-glutathione S-transferase-a sensitive marker of hepatocellular damage associated with acute liver allograft rejection. Transplantation 1994; 58: 1345.
24. Hughes VF, Melvin DG, Niranjan M, Alexander GA, Trull AK,. Clinical validation of an artificial neural network trained to identify acute allograft rejection in liver transplant recipients. Liver Transpl 2001; 7: 496.