Challenges in conducting genome-wide association studies in highly admixed multi-ethnic populations: the Generation R Study

European Journal of Epidemiology

Volumn 30, Issue 4, 2015, Pages 317-330

  Medina Gomez, Carolina ^a   Felix, Janine Frédérique ^a   Estrada, Karol ^a,b,c   Peters, Marjoline Josephine ^a   Herrera, Lizbeth ^a   Kruithof, Claudia Jeanette ^a   Duijts, Liesbeth ^a   Hofman, Albert ^a   van Duijn, Cornelia Marja ^a   Uitterlinden, Andreas Gerardus ^a   Jaddoe, Vincent Wilfred Vishal ^a   Rivadeneira, Fernando ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

Admixed population; Genome wide association studies; Genomic imputation; Multiethnic study; Quality control GWAS

Indexed keywords

AFRICAN AMERICAN; ANCESTRY GROUP; ARTICLE; CHILD; COHORT ANALYSIS; ETHNIC GROUP; EUROPEAN; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENOTYPE; HAPLOTYPE MAP; HISPANIC; HUMAN; MAJOR CLINICAL STUDY; MOROCCAN; POPULATION STRUCTURE; PROSPECTIVE STUDY; QUALITY CONTROL; SURINAMESE; CAUCASIAN; DISEASES; GENETIC LINKAGE; GENETICS; HEALTH SURVEY; NETHERLANDS; PHENOTYPE; STATISTICAL MODEL;

DISEASE; ETHNIC GROUPS; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENETIC LINKAGE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; LOGISTIC MODELS; NETHERLANDS; PHENOTYPE; POPULATION SURVEILLANCE; PROSPECTIVE STUDIES;

EID: 84926372408     PISSN: 03932990     EISSN: 15737284     Source Type: Journal    
DOI: 10.1007/s10654-015-9998-4     Document Type: Article

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