In the hunt for therapeutic targets: Mimicking the growth, metastasis, and stromal associations of early-stage lung cancer using a novel orthotopic animal model

Journal of Thoracic Oncology

Volumn 10, Issue 1, 2015, Pages 46-58

  Weiss, Ido D ^a   Ella, Ezra ^a   Dominsky, Omri ^a   Smith, Yoav ^a   Abraham, Michal ^a   Wald, Hanna ^a   Shlomai, Zippora ^a   Zamir, Gideon ^a   Feigelson, Sara W ^b   Shezen, Elias ^b   Bar Shai, Amir ^b   Alon, Ronen ^b   Izhar, Uzi ^a   Peled, Amnon ^a   Shapira, Oz M ^a   Wald, Ori ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Lung; Non small cell lung cancer; Orthotopic animal model; Tumor microenvironment

Indexed keywords

CHEMOKINE RECEPTOR CCR2; GREEN FLUORESCENT PROTEIN;

ADENOCARCINOMA CELL LINE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CANCER GROWTH; CANCER MODEL; CELL INTERACTION; COMPUTER ASSISTED EMISSION TOMOGRAPHY; DISEASE COURSE; EARLY CANCER; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; LEUKOCYTE; LUNG CANCER; LUNG METASTASIS; LUNG NODULE; LUNG PARENCHYMA; LUNG VOLUME; MOUSE; NONHUMAN; ORTHOTOPIC ANIMAL MODEL; PRIORITY JOURNAL; STROMA CELL; TUMOR CELL INOCULATION; TUMOR MICROENVIRONMENT; ANIMAL; C57BL MOUSE; CARCINOMA, LEWIS LUNG; CARCINOMA, NON-SMALL-CELL LUNG; DISEASE MODEL; DRUG SCREENING; LUNG NEOPLASMS; METASTASIS; PATHOLOGY; TUMOR CELL LINE; XENOGRAFT;

ANIMALS; CARCINOMA, LEWIS LUNG; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; HUMANS; LUNG NEOPLASMS; MICE; MICE, INBRED C57BL; NEOPLASM METASTASIS; TRANSPLANTATION, HETEROLOGOUS; TUMOR MICROENVIRONMENT; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84926336572     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1097/JTO.0000000000000367     Document Type: Article

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