메뉴 건너뛰기




Volumn 9, Issue 9, 2014, Pages

Comparisons of GnRH antagonist versus GnRH agonist protocol in supposed normal ovarian responders undergoing ivf: A systematic review and meta-analysis

Author keywords

[No Author keywords available]

Indexed keywords

CHORIONIC GONADOTROPIN; ESTRADIOL; GONADORELIN AGONIST; GONADORELIN ANTAGONIST; GONADORELIN;

EID: 84926329970     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0106854     Document Type: Review
Times cited : (74)

References (34)
  • 1
    • 84964577885 scopus 로고    scopus 로고
    • Gonadotrophin-releasing hormone antagonists for assisted conception
    • Al-Inany HG, Aboulghar M (2001) Gonadotrophin-releasing hormone antagonists for assisted conception. Cochrane Database Syst Rev 4: CD001750.
    • (2001) Cochrane Database Syst Rev , vol.4 , pp. 001750
    • Al-Inany, H.G.1    Aboulghar, M.2
  • 3
    • 33750210002 scopus 로고    scopus 로고
    • Among patients treated for IVF with gonadotrophins and GnRH analogues,is the probability of live birth dependent on the type of analogue used? A systematic review and meta-analysis
    • Kolibianakis EM, Collins J, Tarlatzis BC, Devroey P, Diedrich K, et al. (2006) Among patients treated for IVF with gonadotrophins and GnRH analogues,is the probability of live birth dependent on the type of analogue used? A systematic review and meta-analysis. Hum Reprod Update 12: 651-671.
    • (2006) Hum Reprod Update , vol.12 , pp. 651-671
    • Kolibianakis, E.M.1    Collins, J.2    Tarlatzis, B.C.3    Devroey, P.4    Diedrich, K.5
  • 5
    • 84874111104 scopus 로고    scopus 로고
    • GnRH agonist versus GnRH antagonist in ovarian stimulation: An ongoing debate
    • Orvieto R, Patrizio P (2013) GnRH agonist versus GnRH antagonist in ovarian stimulation: An ongoing debate. Reprod Biomed Online 26: 4-8.
    • (2013) Reprod Biomed Online , vol.26 , pp. 4-8
    • Orvieto, R.1    Patrizio, P.2
  • 6
    • 84855354176 scopus 로고    scopus 로고
    • Meta-analysis of GnRH antagonist protocols: Do they reduce the risk of OHSS in PCOS?
    • Pundir J, Sunkara SK, El-Toukhy T, Khalaf Y (2012) Meta-analysis of GnRH antagonist protocols: Do they reduce the risk of OHSS in PCOS? Reprod Biomed Online 24: 6-22.
    • (2012) Reprod Biomed Online , vol.24 , pp. 6-22
    • Pundir, J.1    Sunkara, S.K.2    El-Toukhy, T.3    Khalaf, Y.4
  • 8
    • 0034053260 scopus 로고    scopus 로고
    • Ovarian stimulation with HMG: Results of a prospective randomized phase III European study comparing the luteinizing hormone-releasing hormone (LHRH)-antagonist cetrorelix and the LHRH-agonist buserelin
    • European Cetrorelix Study Group
    • Albano C, Felberbaum RE, Smitz J, Riethmü ller-Winzen H, Engel J, et al.(2000) Ovarian stimulation with HMG: Results of a prospective randomized phase III European study comparing the luteinizing hormone-releasing hormone (LHRH)-antagonist cetrorelix and the LHRH-agonist buserelin. European Cetrorelix Study Group. Hum Reprod 15: 526-531.
    • (2000) Hum Reprod , vol.15 , pp. 526-531
    • Albano, C.1    Felberbaum, R.E.2    Smitz, J.3    Riethmüller-Winzen, H.4    Engel, J.5
  • 9
    • 0033807688 scopus 로고    scopus 로고
    • Treatment with the gonadotrophin-releasing hormone antagonist ganirelix in women undergoing ovarianstimulation with recombinant follicle stimulating hormoneis effective, safe and convenient: Results of a controlled,randomized, multicentre trial
    • The European Orgalutran Study Group, Borm G, Mannaerts B (2000) Treatment with the gonadotrophin-releasing hormone antagonist ganirelix in women undergoing ovarianstimulation with recombinant follicle stimulating hormoneis effective, safe and convenient: Results of a controlled,randomized, multicentre trial. Hum Reprod 15: 1490-1498.
    • (2000) Hum Reprod , vol.15 , pp. 1490-1498
    • Borm, G.1    Mannaerts, B.2
  • 10
    • 0033954654 scopus 로고    scopus 로고
    • Prospective randomized, controlled study of in vitro fertilization-embryo transfer with a single dose of a luteinizing hormone-releasing hormone (LHRH) antagonist (cetrorelix) or a depot formula of an LHRH agonist (triptorelin)
    • Olivennes F, Belaisch-Allart, Emperare J, Dechaud H, Alvarez S, et al. (2000) Prospective randomized, controlled study of in vitro fertilization-embryo transfer with a single dose of a luteinizing hormone-releasing hormone (LHRH) antagonist (cetrorelix) or a depot formula of an LHRH agonist (triptorelin). Fertil Steril 73: 314-320.
    • (2000) Fertil Steril , vol.73 , pp. 314-320
    • Olivennes, F.1    Belaisch-Allart Emperare, J.2    Dechaud, H.3    Alvarez, S.4
  • 11
    • 0035070776 scopus 로고    scopus 로고
    • Comparable clinical outcome using the GnRH antagonist ganirelix or a long protocol of the GnRH agonist triptorelin for the prevention of premature LH surges in women undergoing ovarian stimulation
    • European and Middle East Orgalutran Study Group (2001) Comparable clinical outcome using the GnRH antagonist ganirelix or a long protocol of the GnRH agonist triptorelin for the prevention of premature LH surges in women undergoing ovarian stimulation. Hum Reprod 16: 644-651.
    • (2001) Hum Reprod , vol.16 , pp. 644-651
  • 12
    • 0035161913 scopus 로고    scopus 로고
    • Efficacy and safety of ganirelix acetate versus leuprolide acetate in women undergoing controlled ovarian hyperstimulation
    • North American Ganirelix Study Group
    • Fluker M, Grifo J, Leader A, Levy M, Meldrum D, et al. (2001) North American Ganirelix Study Group. Efficacy and safety of ganirelix acetate versus leuprolide acetate in women undergoing controlled ovarian hyperstimulation. Fertil Steril 75: 38-45.
    • (2001) Fertil Steril , vol.75 , pp. 38-45
    • Fluker, M.1    Grifo, J.2    Leader, A.3    Levy, M.4    Meldrum, D.5
  • 13
    • 0037244594 scopus 로고    scopus 로고
    • A randomized comparison of two ovarian stimulation protocols with gonadotropin-releasing hormone (GnRH) antagonist cotreatment for in vitro fertilization commencing recombinant follicle-stimulating hormone on cycle day 2 or 5 with the standard long GnRH agonist protocol
    • Hohmann FP, Macklon NS, Fauser BC (2003) A randomized comparison of two ovarian stimulation protocols with gonadotropin-releasing hormone (GnRH) antagonist cotreatment for in vitro fertilization commencing recombinant follicle-stimulating hormone on cycle day 2 or 5 with the standard long GnRH agonist protocol. The Journal of Clinical Endocrinology and Metabolism 88: 166-173.
    • (2003) The Journal of Clinical Endocrinology and Metabolism , vol.88 , pp. 166-173
    • Hohmann, F.P.1    Macklon, N.S.2    Fauser, B.C.3
  • 15
    • 20444494961 scopus 로고    scopus 로고
    • Ovarian response and follicular development for single-dose and multiple-dose protocols for gonadotropin-releasing hormone antagonist administration
    • Lee TH, Wu MY, Chen HF, Chen MJ, Ho HN, et al. (2005) Ovarian response and follicular development for single-dose and multiple-dose protocols for gonadotropin-releasing hormone antagonist administration. Fertil Steril. 83: 1700-1707.
    • (2005) Fertil Steril. , vol.83 , pp. 1700-1707
    • Lee, T.H.1    Wu, M.Y.2    Chen, H.F.3    Chen, M.J.4    Ho, H.N.5
  • 16
    • 7944220304 scopus 로고    scopus 로고
    • A modified gonadotropin-releasing hormone(GnRH) antagonist protocol failed to increase clinical pregnancy rates in comparison with the long GnRH protocol
    • Loutradis D, Stefanidis K, Drakakis P, Milingos S, Antsaklis A, et al. (2004) A modified gonadotropin-releasing hormone(GnRH) antagonist protocol failed to increase clinical pregnancy rates in comparison with the long GnRH protocol. Fertil Steril 82: 1446-1448.
    • (2004) Fertil Steril , vol.82 , pp. 1446-1448
    • Loutradis, D.1    Stefanidis, K.2    Drakakis, P.3    Milingos, S.4    Antsaklis, A.5
  • 17
    • 8744243139 scopus 로고    scopus 로고
    • Comparative efficacy and safety of cetrorelix with or without mid-cycle recombinant LH and leuprolide acetate for inhibition of premature LH surges in assisted reproduction
    • Sauer MV, Thornton MH 2nd, Schoolcraft W, Frishman GN (2004) Comparative efficacy and safety of cetrorelix with or without mid-cycle recombinant LH and leuprolide acetate for inhibition of premature LH surges in assisted reproduction. Reprod Biomed Online 9: 487-493.
    • (2004) Reprod Biomed Online , vol.9 , pp. 487-493
    • Sauer, M.V.1    Thornton, I.I.M.H.2    Schoolcraft, W.3    Frishman, G.N.4
  • 18
    • 34347242092 scopus 로고    scopus 로고
    • Milder ovarian stimulation for in-vitro fertilization reduces aneuploidy in the human preimplantation embryo: A randomized controlled trial
    • Baart EB, Martini E, Eijkemans MJ, Van Opstal D, Beckers NG, et al. (2007) Milder ovarian stimulation for in-vitro fertilization reduces aneuploidy in the human preimplantation embryo: A randomized controlled trial. Hum Reprod 22: 980-988.
    • (2007) Hum Reprod , vol.22 , pp. 980-988
    • Baart, E.B.1    Martini, E.2    Eijkemans, M.J.3    Van Opstal, D.4    Beckers, N.G.5
  • 19
    • 19744380301 scopus 로고    scopus 로고
    • A randomised study of GnRH antagonist(cetrorelix) versus agonist (busereline) for controlled ovarian stimulation: Effect on safety and efficacy
    • Xavier P, Gamboa C, Calejo L, Silva J, Stevenson D, et al. (2005) A randomised study of GnRH antagonist(cetrorelix) versus agonist (busereline) for controlled ovarian stimulation: Effect on safety and efficacy. Eurpean Journal of Obstetrics, Gynecology, and Reproductive Biology 120: 185-189.
    • (2005) Eurpean Journal of Obstetrics, Gynecology, and Reproductive Biology , vol.120 , pp. 185-189
    • Xavier, P.1    Gamboa, C.2    Calejo, L.3    Silva, J.4    Stevenson, D.5
  • 20
    • 30944454287 scopus 로고    scopus 로고
    • Luteal phase characteristics following GnRH antagonist or agonist treatment-a comparative study
    • Friedler S, Gilboa S, Schachter M, Raziel A, Strassburger D, et al. (2006) Luteal phase characteristics following GnRH antagonist or agonist treatment-a comparative study. Reprod Biomed Online. 12: 27-32
    • (2006) Reprod Biomed Online. , vol.12 , pp. 27-32
    • Friedler, S.1    Gilboa, S.2    Schachter, M.3    Raziel, A.4    Strassburger, D.5
  • 21
    • 33749265289 scopus 로고    scopus 로고
    • Ovarian stimulation with daily late follicular phase administration of low-dose human chorionic gonadotropin for in vitro fertilization: A prospective, randomized trial
    • Serafini P, Yadid I, Motta EL, Alegretti JR, Fioravanti J, et al. (2006) Ovarian stimulation with daily late follicular phase administration of low-dose human chorionic gonadotropin for in vitro fertilization: A prospective, randomized trial. Fertil Steril. 86: 830-838.
    • (2006) Fertil Steril. , vol.86 , pp. 830-838
    • Serafini, P.1    Yadid, I.2    Motta, E.L.3    Alegretti, J.R.4    Fioravanti, J.5
  • 22
    • 29144499138 scopus 로고    scopus 로고
    • A comparative randomized trial to assess the impact of oral contraceptive pretreatment on follicular growth and hormone profiles in GnRH antagonist-treated patients
    • Rombauts L, Healy D, Norman RJ (2006) A comparative randomized trial to assess the impact of oral contraceptive pretreatment on follicular growth and hormone profiles in GnRH antagonist-treated patients. Hum Reprod 21: 95-103.
    • (2006) Hum Reprod , vol.21 , pp. 95-103
    • Rombauts, L.1    Healy, D.2    Norman, R.J.3
  • 23
    • 13544267642 scopus 로고    scopus 로고
    • A randomized prospective trial comparing gonadotropin releasing hormone (GnRH) antagonist/recombinant follicle-stimulating hormone (rFSH) versus GnRH-agonist/rFSH in women pretreated with oral contraceptives before in vitro fertilization
    • Barmat LI, Chantilis SJ, Hurst BS, Dickey RP (2005) A randomized prospective trial comparing gonadotropin releasing hormone (GnRH) antagonist/recombinant follicle-stimulating hormone (rFSH) versus GnRH-agonist/rFSH in women pretreated with oral contraceptives before in vitro fertilization. Fertil Steril 83: 321-330.
    • (2005) Fertil Steril , vol.83 , pp. 321-330
    • Barmat, L.I.1    Chantilis, S.J.2    Hurst, B.S.3    Dickey, R.P.4
  • 24
    • 42949105699 scopus 로고    scopus 로고
    • Comparisons of different dosages of gonadotropin-releasing hormone (GnRH) antagonist, short-acting form and single, half-dose, long acting form of GnRH agonist during controlled ovarian hyperstimulation and in vitro fertilization
    • Hsieh YY, Chang CC, Tsai HD (2008) Comparisons of different dosages of gonadotropin-releasing hormone (GnRH) antagonist, short-acting form and single, half-dose, long acting form of GnRH agonist during controlled ovarian hyperstimulation and in vitro fertilization. Taiwan Journal of Obstetrics and Gynecology 47: 66-74.
    • (2008) Taiwan Journal of Obstetrics and Gynecology , vol.47 , pp. 66-74
    • Hsieh, Y.Y.1    Chang, C.C.2    Tsai, H.D.3
  • 25
    • 59249091013 scopus 로고    scopus 로고
    • Comparison of GnRH agonists and antagonists in normo-responder IVF/ICSI in Turkish female patients
    • Moraloglu O, Kilic S, Karayalçin R, Yuksel B, Tasdemir N, et al. (2008) Comparison of GnRH agonists and antagonists in normo-responder IVF/ICSI in Turkish female patients. Advances in Therapy 25: 266-273.
    • (2008) Advances in Therapy , vol.25 , pp. 266-273
    • Moraloglu, O.1    Kilic, S.2    Karayalçin, R.3    Yuksel, B.4    Tasdemir, N.5
  • 26
    • 67651083461 scopus 로고    scopus 로고
    • Follicular growth and oocyte maturation in GnRH agonist and antagonist protocols for in vitro fertilisation and embryo transfer
    • Depalo R, Lorusso F, Palmisano M, Bassi E, Totaro I, et al. (2009) Follicular growth and oocyte maturation in GnRH agonist and antagonist protocols for in vitro fertilisation and embryo transfer. Gynecol Endocrinol 25: 328-334.
    • (2009) Gynecol Endocrinol , vol.25 , pp. 328-334
    • Depalo, R.1    Lorusso, F.2    Palmisano, M.3    Bassi, E.4    Totaro, I.5
  • 27
    • 62449255303 scopus 로고    scopus 로고
    • IVF/ICSI outcomes between cycles with luteal estradiol (E2) pre-treatment before GnRH antagonist protocol and standard long GnRH agonist protocol: A prospective and randomized study
    • Ye H, Huang G, Zeng P, Pei L (2009) IVF/ICSI outcomes between cycles with luteal estradiol (E2) pre-treatment before GnRH antagonist protocol and standard long GnRH agonist protocol: A prospective and randomized study. Journal of Assisted Reproduction and Genetics 2: 105-111.
    • (2009) Journal of Assisted Reproduction and Genetics , vol.2 , pp. 105-111
    • Ye, H.1    Huang, G.2    Zeng, P.3    Pei, L.4
  • 28
    • 71449083521 scopus 로고    scopus 로고
    • Comparing GnRH agonist long protocol and GnRH antagonist protocol in outcome the first cycle of ART
    • Firouzabadi RD, Ahmadi S, Oskouian H, Davar R (2010) Comparing GnRH agonist long protocol and GnRH antagonist protocol in outcome the first cycle of ART. Arch Gynecol and Obstet 281: 81-85.
    • (2010) Arch Gynecol and Obstet , vol.281 , pp. 81-85
    • Firouzabadi, R.D.1    Ahmadi, S.2    Oskouian, H.3    Davar, R.4
  • 29
    • 84866426688 scopus 로고    scopus 로고
    • A randomized controlled trial of the GnRH antagonist ganirelix in Chinese normal responders: High efficacy and pregnancy rates
    • Qiao J, Lu G, Zhang HW, Chen H, Ma C, et al. (2012) A randomized controlled trial of the GnRH antagonist ganirelix in Chinese normal responders: High efficacy and pregnancy rates. Gynecol Endocrinol. 28: 800-804.
    • (2012) Gynecol Endocrinol. , vol.28 , pp. 800-804
    • Qiao, J.1    Lu, G.2    Zhang, H.W.3    Chen, H.4    Ma, C.5
  • 30
    • 84861568293 scopus 로고    scopus 로고
    • GnRHagonist versus GnRH-antagonist IVF cycles:is the reproductive outcome affected by the incidence of progesterone elevation on the day of HCG triggering? A randomized prospective study
    • Papanikolaou EG, Pados G, Grimbizis G, Bili E, Kyriazi L, et al. (2012) GnRHagonist versus GnRH-antagonist IVF cycles:is the reproductive outcome affected by the incidence of progesterone elevation on the day of HCG triggering? A randomized prospective study. Hum Reprod 27: 1822-1828.
    • (2012) Hum Reprod , vol.27 , pp. 1822-1828
    • Papanikolaou, E.G.1    Pados, G.2    Grimbizis, G.3    Bili, E.4    Kyriazi, L.5
  • 31
    • 84888427593 scopus 로고    scopus 로고
    • The effectiveness of gonadotropin-releasing hormone antagonist in poor ovarian responders undergoing in vitro fertilization: A systematic review and meta-analysis
    • Xiao J, Chang S, Chen S (2013) The effectiveness of gonadotropin-releasing hormone antagonist in poor ovarian responders undergoing in vitro fertilization: A systematic review and meta-analysis. Fertil Steril 100: 1594-1560.
    • (2013) Fertil Steril , vol.100 , pp. 1594-1560
    • Xiao, J.1    Chang, S.2    Chen, S.3
  • 32
    • 84874342234 scopus 로고    scopus 로고
    • Effectiveness of GnRH antagonist in the treatment of patients with polycystic ovary syndrome undergoing IVF: A systematic review and meta analysis
    • Xiao J, Chen S, Zhang C, Chang S (2013) Effectiveness of GnRH antagonist in the treatment of patients with polycystic ovary syndrome undergoing IVF: A systematic review and meta analysis. Gynecol Endocrinol. 29: 187-191.
    • (2013) Gynecol Endocrinol. , vol.29 , pp. 187-191
    • Xiao, J.1    Chen, S.2    Zhang, C.3    Chang, S.4
  • 33
    • 77953841126 scopus 로고    scopus 로고
    • Controlled ovarian hyperstimulation for in vitro fertilization alters endometrial receptivity in humans: Protocol effects
    • Haouzi D, Assou S, Dechanet C, Anahory T, Dechaud H, et al.(2010) Controlled ovarian hyperstimulation for in vitro fertilization alters endometrial receptivity in humans: Protocol effects. Biol Reprod 82: 679-686.
    • (2010) Biol Reprod , vol.82 , pp. 679-686
    • Haouzi, D.1    Assou, S.2    Dechanet, C.3    Anahory, T.4    Dechaud, H.5
  • 34
    • 80053937156 scopus 로고    scopus 로고
    • The dynamics of endometrial growth and the triple layer appearance in three different controlled ovarian hyperstimulation protocols and their influence on IVF outcomes
    • Kuć P, Kuczyńska A, Topczewska M, Tadejko P, Kuczyń ski W (2011)The dynamics of endometrial growth and the triple layer appearance in three different controlled ovarian hyperstimulation protocols and their influence on IVF outcomes. Gynecol Endocrinol 27: 867-873.
    • (2011) Gynecol Endocrinol , vol.27 , pp. 867-873
    • Kuć, P.1    Kuczyńska, A.2    Topczewska, M.3    Tadejko, P.4    Kuczyński, W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.