-
1
-
-
77953543075
-
Navigating the clinical development landscape for oncolytic viruses and other cancer therapeutics: no shortcuts on the road to approval
-
Breitbach C.J., Reid T., Burke J., Bell J.C., Kirn D.H. Navigating the clinical development landscape for oncolytic viruses and other cancer therapeutics: no shortcuts on the road to approval. Cytokine Growth Factor Rev 2010, 21(2-3):85-89.
-
(2010)
Cytokine Growth Factor Rev
, vol.21
, Issue.2-3
, pp. 85-89
-
-
Breitbach, C.J.1
Reid, T.2
Burke, J.3
Bell, J.C.4
Kirn, D.H.5
-
2
-
-
0033152894
-
Intravenous administration of ONYX-015, a selectively replicating adenovirus, induces antitumoral efficacy
-
Heise C.C., Williams A.M., Xue S., Propst M., Kirn D.H. Intravenous administration of ONYX-015, a selectively replicating adenovirus, induces antitumoral efficacy. Cancer Res 1999, 59(11):2623-2628.
-
(1999)
Cancer Res
, vol.59
, Issue.11
, pp. 2623-2628
-
-
Heise, C.C.1
Williams, A.M.2
Xue, S.3
Propst, M.4
Kirn, D.H.5
-
3
-
-
0035134629
-
Clinical research results with dl1520 (Onyx-015), a replication-selective adenovirus for the treatment of cancer: what have we learned?
-
Kirn D. Clinical research results with dl1520 (Onyx-015), a replication-selective adenovirus for the treatment of cancer: what have we learned?. Gene Ther 2001, 8(2):89-98.
-
(2001)
Gene Ther
, vol.8
, Issue.2
, pp. 89-98
-
-
Kirn, D.1
-
4
-
-
76349110981
-
Current issues and future directions of oncolytic adenoviruses
-
Yamamoto M., Curiel D.T. Current issues and future directions of oncolytic adenoviruses. Mol Ther 2010, 18(2):243-250.
-
(2010)
Mol Ther
, vol.18
, Issue.2
, pp. 243-250
-
-
Yamamoto, M.1
Curiel, D.T.2
-
5
-
-
0037314610
-
Aphase I/II trial of intratumoral endoscopic ultrasound injection of ONYX-015 with intravenous gemcitabine in unresectable pancreatic carcinoma
-
Hecht J.R., Bedford R., Abbruzzese J.L., Lahoti S., Reid T.R., Soetikno R.M., et al. Aphase I/II trial of intratumoral endoscopic ultrasound injection of ONYX-015 with intravenous gemcitabine in unresectable pancreatic carcinoma. Clin Cancer Res 2003, 9(2):555-561.
-
(2003)
Clin Cancer Res
, vol.9
, Issue.2
, pp. 555-561
-
-
Hecht, J.R.1
Bedford, R.2
Abbruzzese, J.L.3
Lahoti, S.4
Reid, T.R.5
Soetikno, R.M.6
-
6
-
-
0035887153
-
Aphase I trial of CV706, a replication-competent, PSA selective oncolytic adenovirus, for the treatment of locally recurrent prostate cancer following radiation therapy
-
DeWeese T.L., van der Poel H., Li S., Mikhak B., Drew R., Goemann M., et al. Aphase I trial of CV706, a replication-competent, PSA selective oncolytic adenovirus, for the treatment of locally recurrent prostate cancer following radiation therapy. Cancer Res 2001, 61(20):7464-7472.
-
(2001)
Cancer Res
, vol.61
, Issue.20
, pp. 7464-7472
-
-
DeWeese, T.L.1
van der Poel, H.2
Li, S.3
Mikhak, B.4
Drew, R.5
Goemann, M.6
-
7
-
-
33846650370
-
Clinical trial results with oncolytic virotherapy: a century of promise, a decade of progress
-
Liu T.-C., Galanis E., Kirn D. Clinical trial results with oncolytic virotherapy: a century of promise, a decade of progress. Nat Clin Prac Oncol 2007, 4(2):101-117.
-
(2007)
Nat Clin Prac Oncol
, vol.4
, Issue.2
, pp. 101-117
-
-
Liu, T.-C.1
Galanis, E.2
Kirn, D.3
-
8
-
-
0035863458
-
Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer
-
Nemunaitis J., Khuri F., Ganly I., Arseneau J., Posner M., Vokes E., et al. Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer. JClin Oncol 2001, 19(2):289-298.
-
(2001)
JClin Oncol
, vol.19
, Issue.2
, pp. 289-298
-
-
Nemunaitis, J.1
Khuri, F.2
Ganly, I.3
Arseneau, J.4
Posner, M.5
Vokes, E.6
-
9
-
-
0036828125
-
Hepatic arterial infusion of a replication-selective oncolytic adenovirus (dl1520): phase II viral, immunologic, and clinical endpoints
-
Reid T., Galanis E., Abbruzzese J., Sze D., Wein L.M., Andrews J., et al. Hepatic arterial infusion of a replication-selective oncolytic adenovirus (dl1520): phase II viral, immunologic, and clinical endpoints. Cancer Res 2002, 62(21):6070-6079.
-
(2002)
Cancer Res
, vol.62
, Issue.21
, pp. 6070-6079
-
-
Reid, T.1
Galanis, E.2
Abbruzzese, J.3
Sze, D.4
Wein, L.M.5
Andrews, J.6
-
10
-
-
0033831080
-
Acontrolled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer
-
Khuri F.R., Nemunaitis J., Ganly I., Arseneau J., Tannock I.F., Romel L., et al. Acontrolled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer. Nat Med 2000, 6(8):879-885.
-
(2000)
Nat Med
, vol.6
, Issue.8
, pp. 879-885
-
-
Khuri, F.R.1
Nemunaitis, J.2
Ganly, I.3
Arseneau, J.4
Tannock, I.F.5
Romel, L.6
-
11
-
-
0033926002
-
Replicative adenoviruses for cancer therapy
-
Alemany R., Balagué C., Curiel D. Replicative adenoviruses for cancer therapy. Nat Biotechnol 2000, 18(7):723.
-
(2000)
Nat Biotechnol
, vol.18
, Issue.7
, pp. 723
-
-
Alemany, R.1
Balagué, C.2
Curiel, D.3
-
13
-
-
3442891853
-
Conditionally replicative adenovirus for gastrointestinal cancers
-
Yamamoto M. Conditionally replicative adenovirus for gastrointestinal cancers. Expert Opin Biol Ther 2004, 4(8):1241-1250.
-
(2004)
Expert Opin Biol Ther
, vol.4
, Issue.8
, pp. 1241-1250
-
-
Yamamoto, M.1
-
14
-
-
1542467521
-
Nonreplicating DNA viral vectors for suicide gene therapy: the adenoviral vectors
-
Yamamoto M., Curiel D.T. Nonreplicating DNA viral vectors for suicide gene therapy: the adenoviral vectors. Methods Mol Med 2004, 90:61-70.
-
(2004)
Methods Mol Med
, vol.90
, pp. 61-70
-
-
Yamamoto, M.1
Curiel, D.T.2
-
15
-
-
0035076823
-
Safety and feasibility of injection with an E1B-55 kDa gene-deleted, replication-selective adenovirus (ONYX-015) into primary carcinomas of the pancreas: a phase I trial
-
Mulvihlll S., Warren R., Venook A., Adler A., Randlev B., Heise C., et al. Safety and feasibility of injection with an E1B-55 kDa gene-deleted, replication-selective adenovirus (ONYX-015) into primary carcinomas of the pancreas: a phase I trial. Gene Ther 2001, 8(4):308-315.
-
(2001)
Gene Ther
, vol.8
, Issue.4
, pp. 308-315
-
-
Mulvihlll, S.1
Warren, R.2
Venook, A.3
Adler, A.4
Randlev, B.5
Heise, C.6
-
16
-
-
12944328660
-
Aphase I study of Onyx-015, an E1B attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer
-
Ganly I., Kirn D., Eckhardt S.G., Rodriguez G.I., Soutar D.S., Otto R., et al. Aphase I study of Onyx-015, an E1B attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer. Clin Cancer Res 2000, 6(5):798-806.
-
(2000)
Clin Cancer Res
, vol.6
, Issue.5
, pp. 798-806
-
-
Ganly, I.1
Kirn, D.2
Eckhardt, S.G.3
Rodriguez, G.I.4
Soutar, D.S.5
Otto, R.6
-
17
-
-
0033835016
-
Aprospective phase II trial of ONYX-015 adenovirus and chemotherapy in recurrent squamous cell carcinoma of the head and neck (the Baylor experience)
-
Lamont J.P., Nemunaitis J., Kuhn J.A., Landers S.A., McCarty T.M. Aprospective phase II trial of ONYX-015 adenovirus and chemotherapy in recurrent squamous cell carcinoma of the head and neck (the Baylor experience). Ann Surg Oncol 2000, 7(8):588-592.
-
(2000)
Ann Surg Oncol
, vol.7
, Issue.8
, pp. 588-592
-
-
Lamont, J.P.1
Nemunaitis, J.2
Kuhn, J.A.3
Landers, S.A.4
McCarty, T.M.5
-
18
-
-
0034990761
-
Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: safety, feasibility and biological activity
-
Nemunaitis J., Cunningham C., Buchanan A., Blackburn A., Edelman G., Maples P., et al. Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: safety, feasibility and biological activity. Gene Ther 2001, 8(10):746-759.
-
(2001)
Gene Ther
, vol.8
, Issue.10
, pp. 746-759
-
-
Nemunaitis, J.1
Cunningham, C.2
Buchanan, A.3
Blackburn, A.4
Edelman, G.5
Maples, P.6
-
19
-
-
0037314655
-
Phase II clinical trial of intralesional administration of the oncolytic adenovirus ONYX-015 in patients with hepatobiliary tumors with correlative p53 studies
-
Makower D., Rozenblit A., Kaufman H., Edelman M., Lane M.E., Zwiebel J., et al. Phase II clinical trial of intralesional administration of the oncolytic adenovirus ONYX-015 in patients with hepatobiliary tumors with correlative p53 studies. Clin Cancer Res 2003, 9(2):693-702.
-
(2003)
Clin Cancer Res
, vol.9
, Issue.2
, pp. 693-702
-
-
Makower, D.1
Rozenblit, A.2
Kaufman, H.3
Edelman, M.4
Lane, M.E.5
Zwiebel, J.6
-
20
-
-
0038518576
-
Phase II trial of intravenous CI-1042 in patients with metastatic colorectal cancer
-
Hamid O., Varterasian M.L., Wadler S., Hecht J.R., Benson A., Galanis E., et al. Phase II trial of intravenous CI-1042 in patients with metastatic colorectal cancer. JClin Oncol 2003, 21(8):1498-1504.
-
(2003)
JClin Oncol
, vol.21
, Issue.8
, pp. 1498-1504
-
-
Hamid, O.1
Varterasian, M.L.2
Wadler, S.3
Hecht, J.R.4
Benson, A.5
Galanis, E.6
-
21
-
-
12444281703
-
Pilot trial of intravenous infusion of a replication-selective adenovirus (ONYX-015) in combination with chemotherapy or IL-2 treatment in refractory cancer patients
-
Nemunaitis J., Cunningham C., Tong A.W., Post L., Netto G., Paulson A.S., et al. Pilot trial of intravenous infusion of a replication-selective adenovirus (ONYX-015) in combination with chemotherapy or IL-2 treatment in refractory cancer patients. Cancer Gene Ther 2003, 10(5):341-352.
-
(2003)
Cancer Gene Ther
, vol.10
, Issue.5
, pp. 341-352
-
-
Nemunaitis, J.1
Cunningham, C.2
Tong, A.W.3
Post, L.4
Netto, G.5
Paulson, A.S.6
-
22
-
-
0242320345
-
ONYX-015 enhances radiation-induced death of human anaplastic thyroid carcinoma cells
-
Portella G., Pacelli R., Libertini S., Cella L., Vecchio G., Salvatore M., et al. ONYX-015 enhances radiation-induced death of human anaplastic thyroid carcinoma cells. JClin Endocrinol Metab 2003, 88(10):5027-5032.
-
(2003)
JClin Endocrinol Metab
, vol.88
, Issue.10
, pp. 5027-5032
-
-
Portella, G.1
Pacelli, R.2
Libertini, S.3
Cella, L.4
Vecchio, G.5
Salvatore, M.6
-
23
-
-
1542438707
-
An attenuated adenovirus, ONYX-015, as mouthwash therapy for premalignant oral dysplasia
-
Rudin C.M., Cohen E.E.W., Papadimitrakopoulou V.A., Silverman S., Recant W., El-Naggar A.K., et al. An attenuated adenovirus, ONYX-015, as mouthwash therapy for premalignant oral dysplasia. JClin Oncol 2003, 21(24):4546-4552.
-
(2003)
JClin Oncol
, vol.21
, Issue.24
, pp. 4546-4552
-
-
Rudin, C.M.1
Cohen, E.E.W.2
Papadimitrakopoulou, V.A.3
Silverman, S.4
Recant, W.5
El-Naggar, A.K.6
-
24
-
-
7044228126
-
Aphase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant gliomas, in the adjuvant setting
-
Chiocca E.A., Abbed K.M., Tatter S., Louis D.N., Hochberg F.H., Barker F., et al. Aphase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant gliomas, in the adjuvant setting. Mol Ther 2004, 10(5):958-966.
-
(2004)
Mol Ther
, vol.10
, Issue.5
, pp. 958-966
-
-
Chiocca, E.A.1
Abbed, K.M.2
Tatter, S.3
Louis, D.N.4
Hochberg, F.H.5
Barker, F.6
-
25
-
-
20144368516
-
Phase I-II trial of ONYX-015 in combination with MAP chemotherapy in patients with advanced sarcomas
-
Galanis E., Okuno S.H., Nascimento A.G., Lewis B.D., Lee R.A., Oliveira A.M., et al. Phase I-II trial of ONYX-015 in combination with MAP chemotherapy in patients with advanced sarcomas. Gene Ther 2005, 12(5):437-445.
-
(2005)
Gene Ther
, vol.12
, Issue.5
, pp. 437-445
-
-
Galanis, E.1
Okuno, S.H.2
Nascimento, A.G.3
Lewis, B.D.4
Lee, R.A.5
Oliveira, A.M.6
-
26
-
-
22944476168
-
Effects of Onyx-015 among metastatic colorectal cancer patients that have failed prior treatment with 5-FU/leucovorin
-
Reid T.R., Freeman S., Post L., McCormick F., Sze D.Y. Effects of Onyx-015 among metastatic colorectal cancer patients that have failed prior treatment with 5-FU/leucovorin. Cancer Gene Ther 2005, 12(8):673-681.
-
(2005)
Cancer Gene Ther
, vol.12
, Issue.8
, pp. 673-681
-
-
Reid, T.R.1
Freeman, S.2
Post, L.3
McCormick, F.4
Sze, D.Y.5
-
27
-
-
35048816872
-
Aphase I trial of intravenous infusion of ONYX-015 and enbrel in solid tumor patients
-
Nemunaitis J., Senzer N., Sarmiento S., Zhang Y.A., Arzaga R., Sands B., et al. Aphase I trial of intravenous infusion of ONYX-015 and enbrel in solid tumor patients. Cancer Gene Ther 2007, 14(11):885-893.
-
(2007)
Cancer Gene Ther
, vol.14
, Issue.11
, pp. 885-893
-
-
Nemunaitis, J.1
Senzer, N.2
Sarmiento, S.3
Zhang, Y.A.4
Arzaga, R.5
Sands, B.6
-
28
-
-
80052969083
-
Deletion analysis of Ad5 E1a transcriptional control region: impact on tumor-selective expression of E1a and E1b
-
Epub 2011/08/06
-
Hedjran F., Shantanu K., Tony R. Deletion analysis of Ad5 E1a transcriptional control region: impact on tumor-selective expression of E1a and E1b. Cancer Gene Ther 2011, 18(10):717-723. Epub 2011/08/06.
-
(2011)
Cancer Gene Ther
, vol.18
, Issue.10
, pp. 717-723
-
-
Hedjran, F.1
Shantanu, K.2
Tony, R.3
-
29
-
-
33745191473
-
Concurrent delivery of GM-CSF and B7-1 using an oncolytic adenovirus elicits potent antitumor effect
-
Choi K.J., Kim J.H., Lee Y.S., Kim J., Suh B.S., Kim H., et al. Concurrent delivery of GM-CSF and B7-1 using an oncolytic adenovirus elicits potent antitumor effect. Gene Ther 2006, 13(13):1010-1020.
-
(2006)
Gene Ther
, vol.13
, Issue.13
, pp. 1010-1020
-
-
Choi, K.J.1
Kim, J.H.2
Lee, Y.S.3
Kim, J.4
Suh, B.S.5
Kim, H.6
-
30
-
-
0037812877
-
Invitro and invivo activities of an oncolytic adenoviral vector designed to express GM-CSF
-
Bristol J.A., Zhu M., Ji H., Mina M., Xie Y., Clarke L., et al. Invitro and invivo activities of an oncolytic adenoviral vector designed to express GM-CSF. Mol Ther 2003, 7(6):755-764.
-
(2003)
Mol Ther
, vol.7
, Issue.6
, pp. 755-764
-
-
Bristol, J.A.1
Zhu, M.2
Ji, H.3
Mina, M.4
Xie, Y.5
Clarke, L.6
-
31
-
-
0030429009
-
Granulocyte-macrophage colony-stimulating factor as an adjuvant in tumor immunotherapy
-
Fagerberg J. Granulocyte-macrophage colony-stimulating factor as an adjuvant in tumor immunotherapy. Med Oncol 1996, 13(3):155-160.
-
(1996)
Med Oncol
, vol.13
, Issue.3
, pp. 155-160
-
-
Fagerberg, J.1
-
32
-
-
0036198993
-
Bilamellar cationic liposomes protect adenovectors from preexisting humoral immune responses
-
Yotnda P., Chen D.-H., Chiu W., Piedra P.A., Davis A., Templeton N.S., et al. Bilamellar cationic liposomes protect adenovectors from preexisting humoral immune responses. Mol Ther 2002, 5(3):233-241.
-
(2002)
Mol Ther
, vol.5
, Issue.3
, pp. 233-241
-
-
Yotnda, P.1
Chen, D.-H.2
Chiu, W.3
Piedra, P.A.4
Davis, A.5
Templeton, N.S.6
-
34
-
-
79958261310
-
Anionic liposomes enhance and prolong adenovirus-mediated gene expression in airway epithelia invitro and invivo
-
Zhong Z., Han J., Wan Y., Zhang Z., Sun X. Anionic liposomes enhance and prolong adenovirus-mediated gene expression in airway epithelia invitro and invivo. Mol Pharmacol 2011, 8(3):673-682.
-
(2011)
Mol Pharmacol
, vol.8
, Issue.3
, pp. 673-682
-
-
Zhong, Z.1
Han, J.2
Wan, Y.3
Zhang, Z.4
Sun, X.5
-
35
-
-
76249124117
-
Anionic liposomes increase the efficiency of adenovirus-mediated gene transfer to coxsackie-adenovirus receptor deficient cells
-
Zhong Z., Shi S., Han J., Zhang Z., Sun X. Anionic liposomes increase the efficiency of adenovirus-mediated gene transfer to coxsackie-adenovirus receptor deficient cells. Mol Pharmacol 2009, 7(1):105-115.
-
(2009)
Mol Pharmacol
, vol.7
, Issue.1
, pp. 105-115
-
-
Zhong, Z.1
Shi, S.2
Han, J.3
Zhang, Z.4
Sun, X.5
-
36
-
-
80054073377
-
Improvement of adenoviral vector-mediated gene transfer to airway epithelia by folate-modified anionic liposomes
-
Zhong Z., Wan Y., Han J., Shi S., Zhang Z., Sun X. Improvement of adenoviral vector-mediated gene transfer to airway epithelia by folate-modified anionic liposomes. Int J Nanomed 2011, 6:1083.
-
(2011)
Int J Nanomed
, vol.6
, pp. 1083
-
-
Zhong, Z.1
Wan, Y.2
Han, J.3
Shi, S.4
Zhang, Z.5
Sun, X.6
-
37
-
-
84862829851
-
Evolution of oncolytic adenovirus for cancer treatment
-
Choi J.-W., Lee J.-S., Kim S.W., Yun C.-O. Evolution of oncolytic adenovirus for cancer treatment. Adv Drug Deliv Rev 2012, 64(8):720-729.
-
(2012)
Adv Drug Deliv Rev
, vol.64
, Issue.8
, pp. 720-729
-
-
Choi, J.-W.1
Lee, J.-S.2
Kim, S.W.3
Yun, C.-O.4
-
38
-
-
4744357460
-
Overview of interleukin-2 function, production and clinical applications
-
Gaffen S.L., Liu K.D. Overview of interleukin-2 function, production and clinical applications. Cytokine 2004, 28(3):109-123.
-
(2004)
Cytokine
, vol.28
, Issue.3
, pp. 109-123
-
-
Gaffen, S.L.1
Liu, K.D.2
-
39
-
-
17144451105
-
Cytokine gene therapy of cancer using interleukin-12: murine and clinical trials
-
Lotze M.T., Zitvogel L., Campbell R., Robbins P.D., Elder E., Haluszczak C., et al. Cytokine gene therapy of cancer using interleukin-12: murine and clinical trials. Ann N Y Acad Sci 1996, 795(1):440-454.
-
(1996)
Ann N Y Acad Sci
, vol.795
, Issue.1
, pp. 440-454
-
-
Lotze, M.T.1
Zitvogel, L.2
Campbell, R.3
Robbins, P.D.4
Elder, E.5
Haluszczak, C.6
-
40
-
-
0034980914
-
Sequestration of adenoviral vector by kupffer cells leads to a nonlinear dose response of transduction in liver
-
Tao N., Gao G.-P., Parr M., Johnston J., Baradet T., Wilson J.M., et al. Sequestration of adenoviral vector by kupffer cells leads to a nonlinear dose response of transduction in liver. Mol Ther 2001, 3(1):28-35.
-
(2001)
Mol Ther
, vol.3
, Issue.1
, pp. 28-35
-
-
Tao, N.1
Gao, G.-P.2
Parr, M.3
Johnston, J.4
Baradet, T.5
Wilson, J.M.6
-
41
-
-
38849134279
-
Adenovirus serotype 5 hexon mediates liver gene transfer
-
Waddington S.N., McVey J.H., Bhella D., Parker A.L., Barker K., Atoda H., et al. Adenovirus serotype 5 hexon mediates liver gene transfer. Cell 2008, 132(3):397-409.
-
(2008)
Cell
, vol.132
, Issue.3
, pp. 397-409
-
-
Waddington, S.N.1
McVey, J.H.2
Bhella, D.3
Parker, A.L.4
Barker, K.5
Atoda, H.6
-
42
-
-
21044439669
-
Neutralizing antibodies to adenovirus serotype 5 vaccine vectors are directed primarily against the adenovirus hexon protein
-
Sumida S.M., Truitt D.M., Lemckert A.A., Vogels R., Custers J.H., Addo M.M., et al. Neutralizing antibodies to adenovirus serotype 5 vaccine vectors are directed primarily against the adenovirus hexon protein. JImmunol 2005, 174(11):7179-7185.
-
(2005)
JImmunol
, vol.174
, Issue.11
, pp. 7179-7185
-
-
Sumida, S.M.1
Truitt, D.M.2
Lemckert, A.A.3
Vogels, R.4
Custers, J.H.5
Addo, M.M.6
-
43
-
-
33646586362
-
Hexon-chimaeric adenovirus serotype 5 vectors circumvent pre-existing anti-vector immunity
-
Roberts D.M., Nanda A., Havenga M.J.E., Abbink P., Lynch D.M., Ewald B.A., et al. Hexon-chimaeric adenovirus serotype 5 vectors circumvent pre-existing anti-vector immunity. Nature 2006, 441(7090):239-243.
-
(2006)
Nature
, vol.441
, Issue.7090
, pp. 239-243
-
-
Roberts, D.M.1
Nanda, A.2
Havenga, M.J.E.3
Abbink, P.4
Lynch, D.M.5
Ewald, B.A.6
-
44
-
-
54949092481
-
Targeting of adenovirus vectors to the LRP receptor family with the high-affinity ligand RAP via combined genetic and chemical modification of the pIX capsomere
-
Corjon S., Wortmann A., Engler T., van Rooijen N., Kochanek S., Kreppel F. Targeting of adenovirus vectors to the LRP receptor family with the high-affinity ligand RAP via combined genetic and chemical modification of the pIX capsomere. Mol Ther 2008, 16(11):1813-1824.
-
(2008)
Mol Ther
, vol.16
, Issue.11
, pp. 1813-1824
-
-
Corjon, S.1
Wortmann, A.2
Engler, T.3
van Rooijen, N.4
Kochanek, S.5
Kreppel, F.6
-
45
-
-
78650881455
-
Modifications of adenovirus hexon allow for either hepatocyte detargeting or targeting with potential evasion from kupffer cells
-
Prill J.-M., Espenlaub S., Samen U., Engler T., Schmidt E., Vetrini F., et al. Modifications of adenovirus hexon allow for either hepatocyte detargeting or targeting with potential evasion from kupffer cells. Mol Ther 2011, 19(1):83-92.
-
(2011)
Mol Ther
, vol.19
, Issue.1
, pp. 83-92
-
-
Prill, J.-M.1
Espenlaub, S.2
Samen, U.3
Engler, T.4
Schmidt, E.5
Vetrini, F.6
-
46
-
-
33646861014
-
Comparison of adenovirus fiber, protein IX, and hexon capsomeres as scaffolds for vector purification and cell targeting
-
Campos S.K., Barry M.A. Comparison of adenovirus fiber, protein IX, and hexon capsomeres as scaffolds for vector purification and cell targeting. Virology 2006, 349(2):453-462.
-
(2006)
Virology
, vol.349
, Issue.2
, pp. 453-462
-
-
Campos, S.K.1
Barry, M.A.2
-
47
-
-
0031824396
-
Poly (lactic-glycolic) acid copolymer encapsulation of recombinant adenovirus reduces immunogenicity invivo
-
Beer S.J., Matthews C.B., Stein C.S., Ross B.D., Hilfinger J.M., Davidson B.L. Poly (lactic-glycolic) acid copolymer encapsulation of recombinant adenovirus reduces immunogenicity invivo. Gene Ther 1998, 5(6):740-746.
-
(1998)
Gene Ther
, vol.5
, Issue.6
, pp. 740-746
-
-
Beer, S.J.1
Matthews, C.B.2
Stein, C.S.3
Ross, B.D.4
Hilfinger, J.M.5
Davidson, B.L.6
-
48
-
-
0033753867
-
Enhancement of adenoviral transduction with polycationic liposomes invivo
-
Lee S.G., Yoon S.J., Kim C.D., Kim K., Lim D.S., Yeom Y.I., et al. Enhancement of adenoviral transduction with polycationic liposomes invivo. Cancer Gene Ther 2000, 7(10).
-
(2000)
Cancer Gene Ther
, vol.7
, Issue.10
-
-
Lee, S.G.1
Yoon, S.J.2
Kim, C.D.3
Kim, K.4
Lim, D.S.5
Yeom, Y.I.6
-
49
-
-
0036844766
-
Invivo characteristics of cationic liposomes as delivery vectors for gene therapy
-
Audouy S.L., de Leij L.M.H., Hoekstra D., Molema G. Invivo characteristics of cationic liposomes as delivery vectors for gene therapy. Pharm Res 2002, 19(11):1599-1605.
-
(2002)
Pharm Res
, vol.19
, Issue.11
, pp. 1599-1605
-
-
Audouy, S.L.1
de Leij, L.M.H.2
Hoekstra, D.3
Molema, G.4
-
50
-
-
0001315972
-
Major limitations in the use of cationic liposomes for DNA delivery
-
Filion M.C., Phillips N.C. Major limitations in the use of cationic liposomes for DNA delivery. Int J Pharm 1998, 162(1-2):159-170.
-
(1998)
Int J Pharm
, vol.162
, Issue.1-2
, pp. 159-170
-
-
Filion, M.C.1
Phillips, N.C.2
-
51
-
-
33746438424
-
Toxicity of cationic lipids and cationic polymers in gene delivery
-
Lv H., Zhang S., Wang B., Cui S., Yan J. Toxicity of cationic lipids and cationic polymers in gene delivery. JControl Release 2006, 114(1):100-109.
-
(2006)
JControl Release
, vol.114
, Issue.1
, pp. 100-109
-
-
Lv, H.1
Zhang, S.2
Wang, B.3
Cui, S.4
Yan, J.5
-
52
-
-
1642533551
-
Pharmacokinetics and tumor retention of 125I-labeled RGD peptide are improved by PEGylation
-
Chen X., Park R., Shahinian A.H., Bading J.R., Conti P.S. Pharmacokinetics and tumor retention of 125I-labeled RGD peptide are improved by PEGylation. Nucl Med Biol 2004, 31(1):11-19.
-
(2004)
Nucl Med Biol
, vol.31
, Issue.1
, pp. 11-19
-
-
Chen, X.1
Park, R.2
Shahinian, A.H.3
Bading, J.R.4
Conti, P.S.5
-
53
-
-
26944452043
-
PEGylation, successful approach to drug delivery
-
Veronese F.M., Pasut G. PEGylation, successful approach to drug delivery. Drug Discov Today 2005, 10(21):1451-1458.
-
(2005)
Drug Discov Today
, vol.10
, Issue.21
, pp. 1451-1458
-
-
Veronese, F.M.1
Pasut, G.2
-
54
-
-
0019324697
-
Effect of the cholesterol content of small unilamellar liposomes on their stability invivo and invitro
-
Kirby C., Clarke J., Gregoriadis G. Effect of the cholesterol content of small unilamellar liposomes on their stability invivo and invitro. Biochem J 1980, 186(2):591-598.
-
(1980)
Biochem J
, vol.186
, Issue.2
, pp. 591-598
-
-
Kirby, C.1
Clarke, J.2
Gregoriadis, G.3
-
55
-
-
0025731906
-
Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives invivo
-
Allen T.M., Hansen C., Martin F., Redemann C., Yau-Young A. Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives invivo. Biochim Biophys Acta - Biomembr 1991, 1066(1):29-36.
-
(1991)
Biochim Biophys Acta - Biomembr
, vol.1066
, Issue.1
, pp. 29-36
-
-
Allen, T.M.1
Hansen, C.2
Martin, F.3
Redemann, C.4
Yau-Young, A.5
|