Anti-malarial activity and toxicity assessment of Himatanthus articulatus, a plant used to treat malaria in the Brazilian Amazon

Malaria Journal

Volumn 14, Issue 1, 2015, Pages

  Vale, Valdicley V ^a   Vilhena, Thyago C ^a   Trindade, Rafaela C Santos ^b   Ferreira, Márlia Regina C ^b   Percário, Sandro ^a,e   Soares, Luciana F ^c   Pereira, Washington Luiz A ^d   Brandão, Geraldo C ^f   Oliveira, Alaíde B ^a,c   Dolabela, Maria F ^a   De Vasconcelos, Flávio ^a  

^a FEDERAL UNIVERSITY OF PARÁ   (Brazil)

^b MUSEU PARAENSE EMÍLIO GOELDI   (Brazil)

^c FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^d UNIVERSIDADE FEDERAL RURAL DA AMAZÔNIA   (Brazil)

^e CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^f FEDERAL UNIVERSITY OF OURO PRETO   (Brazil)

Author keywords

Himatanthus articulatus; Malaria; Oxidative stress; Plumieride; Toxicity

Indexed keywords

ANTIMALARIAL AGENT; BETA AMYRIN CINNAMATE; CHLOROQUINE; ISOPLUMERICIN; ISOPLUMIERIDE; LUPEOL ACETATE; LUPEOL CINNAMATE; NITRIC ACID DERIVATIVE; NITRIC OXIDE; NITRITE; PLANT MEDICINAL PRODUCT; PLUMERICIN; PLUMIERIDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG; PLANT EXTRACT;

ALPHA AMYRIN CINNAMATE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIMALARIAL ACTIVITY; ARTICLE; BARK; BRAZIL; CARBON NUCLEAR MAGNETIC RESONANCE; CELL FRACTIONATION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG IDENTIFICATION; DRUG SCREENING; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIMATANTHUS ARTICULATUS; IN VITRO STUDY; IN VIVO STUDY; LIPID PEROXIDATION; MALARIA; MALARIA FALCIPARUM; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PLASMODIUM BERGHEI; PROTON NUCLEAR MAGNETIC RESONANCE; RESPIRATORY EPITHELIUM; TRADITIONAL MEDICINE; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ANIMAL; APOCYNACEAE; CELL LINE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; HUMAN; ISOLATION AND PURIFICATION; PARASITEMIA; PLANT STEM; PLASMODIUM FALCIPARUM; TREATMENT OUTCOME;

ANIMALS; ANTIMALARIALS; APOCYNACEAE; BRAZIL; CELL LINE; CELL SURVIVAL; FEMALE; HUMANS; MALARIA; MALE; MICE; PARASITEMIA; PLANT BARK; PLANT EXTRACTS; PLANT STEMS; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; TREATMENT OUTCOME;

EID: 84925989312     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/s12936-015-0643-1     Document Type: Article

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