Lentiviral Vector-Mediated dopamine D3 receptor modulation in the rat brain impairs alcohol intake and ethanol-induced conditioned place preference

Alcoholism: Clinical and Experimental Research

Volumn 38, Issue 9, 2014, Pages 2369-2376

  Bahi, Amine ^a   Dreyer, Jean Luc ^b  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^b UNIVERSITY OF FRIBOURG   (Switzerland)

Author keywords

Alcoholism; Conditioned place preference; Gene therapy; Lentivirus; SiRNA; Two bottle choice

Indexed keywords

2 DIPROPYLAMINO 7 HYDROXYTETRALIN; DOPAMINE 3 RECEPTOR; LENTIVIRUS VECTOR; N [4 [2 (6 CYANO 1,2,3,4 TETRAHYDRO 2 ISOQUINOLINYL)ETHYL]CYCLOHEXYL] 4 QUINOLINECARBOXAMIDE; QUININE; SACCHARIN; ALCOHOL;

ADULT; ALCOHOL CONSUMPTION; ALCOHOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GAIN OF FUNCTION MUTATION; GENE OVEREXPRESSION; GENE SILENCING; GENETIC ASSOCIATION; LOSS OF FUNCTION MUTATION; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PATHOGENESIS; PLACE PREFERENCE; PRIORITY JOURNAL; RAT; ADMINISTRATION AND DOSAGE; ANIMAL; BIOSYNTHESIS; BRAIN; CONDITIONING; DRINKING BEHAVIOR; DRUG EFFECTS; GENE VECTOR; GENETICS; LENTIVIRINAE; METABOLISM; PHYSIOLOGY; PROCEDURES; WISTAR RAT;

LENTIVIRUS; MUS; RATTUS;

ALCOHOL DRINKING; ANIMALS; BRAIN; CONDITIONING (PSYCHOLOGY); ETHANOL; GENE KNOCKDOWN TECHNIQUES; GENETIC VECTORS; LENTIVIRUS; MALE; RATS; RATS, WISTAR; RECEPTORS, DOPAMINE D3;

EID: 84925965122     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/acer.12503     Document Type: Article

References (42)

1. Asin KE, Wirtshafter D, Tabakoff B (1985) Failure to establish a conditioned place preference with ethanol in rats. Pharmacol Biochem Behav 22:169-173.
2. Bahi A (2012) Viral-mediated knockdown of mGluR7 in the nucleus accumbens mediates excessive alcohol drinking and increased ethanol-elicited conditioned place preference in rats. Neuropsychopharmacology 38:2109-2119.
3. Bahi A (2013a) Individual differences in elevated plus-maze exploration predicted higher ethanol consumption and preference in outbred mice. Pharmacol Biochem Behav 105:83-88.
4. Bahi A (2013b) Viral-mediated knockdown of mGluR7 in the nucleus accumbens mediates excessive alcohol drinking and increased ethanol-elicited conditioned place preference in rats. Neuropsychopharmacology 38:2109-2119.
5. Bahi A, Boyer F, Bussard G, Dreyer JL (2005) Silencing dopamine D3-receptors in the nucleus accumbens shell in vivo induces changes in cocaine-induced hyperlocomotion. Eur J Neurosci 21:3415-3426.
6. Bahi A, Boyer F, Kafri T, Dreyer JL (2004) CD81-induced behavioural changes during chronic cocaine administration: in vivo gene delivery with regulatable lentivirus. Eur J Neurosci 19:1621-1633.
7. Bahi A, Dreyer JL (2012) Involvement of nucleus accumbens dopamine D1 receptors in ethanol drinking, ethanol-induced conditioned place preference, and ethanol-induced psychomotor sensitization in mice. Psychopharmacology 222:141-153.
8. Bahi A, Dreyer JL (2013) Striatal modulation of BDNF expression using microRNA124a-expressing lentiviral vectors impairs ethanol-induced conditioned-place preference and voluntary alcohol consumption. Eur J Neurosci 38:2328-2337.
9. Bahi A, Fizia K, Dietz M, Gasparini F, Flor PJ (2012) Pharmacological modulation of mGluR7 with AMN082 and MMPIP exerts specific influences on alcohol consumption and preference in rats. Addict Biol 17:235-247.
10. Bahi A, Tolle V, Fehrentz JA, Brunel L, Martinez J, Tomasetto CL, Karam SM (2013) Ghrelin knockout mice show decreased voluntary alcohol consumption and reduced ethanol-induced conditioned place preference. Peptides 43C:48-55.
11. Boyce JM, Risinger FO (2000) Enhancement of ethanol reward by dopamine D3 receptor blockade. Brain Res 880:202-206.
12. Boyce-Rustay JM, Risinger FO (2003) Dopamine D3 receptor knockout mice and the motivational effects of ethanol. Pharmacol Biochem Behav 75:373-379.
13. Bozarth MA (1990) Evidence for the rewarding effects of ethanol using the conditioned place preference method. Pharmacol Biochem Behav 35:485-487.
14. Caine SB, Koob GF (1993) Modulation of cocaine self-administration in the rat through D-3 dopamine receptors. Science 260:1814-1816.
15. Ciccocioppo R, Panocka I, Froldi R, Quitadamo E, Massi M (1999) Ethanol induces conditioned place preference in genetically selected alcohol-preferring rats. Psychopharmacology 141:235-241.
16. Cohen C, Perrault G, Sanger DJ (1998) Preferential involvement of D3 versus D2 dopamine receptors in the effects of dopamine receptor ligands on oral ethanol self-administration in rats. Psychopharmacology 140:478-485.
17. Depoortere R, Perrault G, Sanger DJ (1996) Behavioural effects in the rat of the putative dopamine D3 receptor agonist 7-OH-DPAT: comparison with quinpirole and apomorphine. Psychopharmacology 124:231-240.
18. Di Ciano P, Underwood RJ, Hagan JJ, Everitt BJ (2003) Attenuation of cue-controlled cocaine-seeking by a selective D3 dopamine receptor antagonist SB-277011-A. Neuropsychopharmacology 28:329-338.
19. Everitt BJ, Robbins TW (2005) Neural systems of reinforcement for drug addiction: from actions to habits to compulsion. Nat Neurosci 8:1481-1489.
20. Fernandes AR, Easton AC, De Souza Silva MA, Schumann G, Muller CP, Desrivieres S (2012) Lentiviral-mediated gene delivery reveals distinct roles of nucleus accumbens dopamine D2 and D3 receptors in novelty- and light-induced locomotor activity. Eur J Neurosci 35:1344-1353.
21. Ferrari F, Giuliani D (1997) Effects of (-)eticlopride and 7-OH-DPAT on the tail-suspension test in mice. J Psychopharmacol 11:339-344.
22. Frantz K, Babcock D, Van Hartesveldt C (1996) The locomotor effects of a putative dopamine D3 receptor agonist in developing rats. Eur J Pharmacol 302:1-6.
23. Gainetdinov RR, Sotnikova TD, Grekhova TV, Rayevsky KS (1996) In vivo evidence for preferential role of dopamine D3 receptor in the presynaptic regulation of dopamine release but not synthesis. Eur J Pharmacol 308:261-269.
24. Gilbert JG, Newman AH, Gardner EL, Ashby CR Jr, Heidbreder CA, Pak AC, Peng XQ, Xi ZX (2005) Acute administration of SB-277011A, NGB 2904, or BP 897 inhibits cocaine cue-induced reinstatement of drug-seeking behavior in rats: role of dopamine D3 receptors. Synapse 57:17-28.
25. Harrison SJ, Nobrega JN (2009) A functional role for the dopamine D3 receptor in the induction and expression of behavioural sensitization to ethanol in mice. Psychopharmacology 207:47-56.
26. Heidbreder CA, Andreoli M, Marcon C, Thanos PK, Ashby CR Jr, Gardner EL (2004) Role of dopamine D3 receptors in the addictive properties of ethanol. Drugs Today (Barc) 40:355-365.
27. Kamei J, Saitoh A (1996) Modification of the effects of 7-OH-DPAT, a dopamine D3-receptor agonist, on morphine-induced hyperlocomotion by diabetes. Life Sci 59:773-780.
28. Le Foll B, Frances H, Diaz J, Schwartz JC, Sokoloff P (2002) Role of the dopamine D3 receptor in reactivity to cocaine-associated cues in mice. Eur J Neurosci 15:2016-2026.
29. Narita M, Soma M, Tamaki H, Narita M, Suzuki T (2002) Intensification of the development of ethanol dependence in mice lacking dopamine D(3) receptor. Neurosci Lett 324:129-132.
30. Newman AH, Grundt P, Nader MA (2005) Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. J Med Chem 48:3663-3679.
31. Quertemont E, De Witte P (2001) Conditioned stimulus preference after acetaldehyde but not ethanol injections. Pharmacol Biochem Behav 68:449-454.
32. Reid LD, Hunter GA, Beaman CM, Hubbell CL (1985) Toward understanding ethanol's capacity to be reinforcing: a conditioned place preference following injections of ethanol. Pharmacol Biochem Behav 22:483-487.
33. Richtand NM, Goldsmith RJ, Nolan JE, Berger SP (2001) The D3 dopamine receptor and substance dependence. J Addict Dis 20:19-32.
34. Silvestre JS, O'Neill MF, Fernandez AG, Palacios JM (1996) Effects of a range of dopamine receptor agonists and antagonists on ethanol intake in the rat. Eur J Pharmacol 318:257-265.
35. Sokoloff P, Schwartz JC (1995) Novel dopamine receptors half a decade later. Trends Pharmacol Sci 16:270-275.
36. Spanagel R, Heilig M (2005) Addiction and its brain science. Addiction 100:1813-1822.
37. Spanagel R, Weiss F (1999) The dopamine hypothesis of reward: past and current status. Trends Neurosci 22:521-527.
38. Starr MS, Starr BS (1995) Motor actions of 7-OH-DPAT in normal and reserpine-treated mice suggest involvement of both dopamine D2 and D3 receptors. Eur J Pharmacol 277:151-158.
39. Thanos PK, Katana JM, Ashby CR Jr, Michaelides M, Gardner EL, Heidbreder CA, Volkow ND (2005) The selective dopamine D3 receptor antagonist SB-277011-A attenuates ethanol consumption in ethanol preferring (P) and non-preferring (NP) rats. Pharmacol Biochem Behav 81:190-197.
40. Tzschentke TM (2007) Measuring reward with the conditioned place preference (CPP) paradigm: update of the last decade. Addict Biol 12:227-462.
41. Uzbay IT, Kayir H (2003) Bromocriptine and quinpirole, but not 7-OH-DPAT or SKF 38393, potentiate the inhibitory effect of L-NAME on ethanol-induced locomotor activity in mice. Naunyn Schmiedebergs Arch Pharmacol 367:414-421.
42. Vengeliene V, Leonardi-Essmann F, Perreau-Lenz S, Gebicke-Haerter P, Drescher K, Gross G, Spanagel R (2006) The dopamine D3 receptor plays an essential role in alcohol-seeking and relapse. FASEB J 20:2223-2233.