Genetic Profiles of Fluoroquinolone-Nonsusceptible Klebsiella pneumoniae among Cephalosporin-Resistant K. pneumoniae

Microbial Drug Resistance

Volumn 21, Issue 2, 2015, Pages 224-233

  Nagasaka, Yukiko ^a   Kimura, Kouji ^a   Yamada, Keiko ^a   Wachino, Jun Ichi ^a   Jin, Wanchun ^a   Notake, Shigeyuki ^b   Yanagisawa, Hideji ^b   Arakawa, Yoshichika ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Miroku Medical Laboratory Co   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; BETA LACTAMASE; BETA LACTAMASE CTX M; CEFEPIME; CEFMINOX; CEFOTAXIME; CEFTAZIDIME; CEPHALOSPORIN; CIPROFLOXACIN; COLISTIN; FOSFOMYCIN; GENTAMICIN; IMIPENEM; LEVOFLOXACIN; QUINOLONE; QUINOLONE DERIVATIVE; TIGECYCLINE; ANTIINFECTIVE AGENT; CEPHALOSPORIN DERIVATIVE;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIUM ISOLATE; GENE TRANSFER; GYRA GENE; JAPAN; KLEBSIELLA PNEUMONIAE; MULTILOCUS SEQUENCE TYPING; NONHUMAN; PARC GENE; PLASMID MEDIATED QUINOLONE RESISTANCE GENE; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; REPLICON; DRUG EFFECTS; GENETICS; MULTIDRUG RESISTANCE;

KLEBSIELLA PNEUMONIAE;

AMINO ACID SUBSTITUTION; ANTI-BACTERIAL AGENTS; BETA-LACTAMASES; CEPHALOSPORINS; CIPROFLOXACIN; DRUG RESISTANCE, MULTIPLE, BACTERIAL; FLUOROQUINOLONES; GENES, BACTERIAL; JAPAN; KLEBSIELLA PNEUMONIAE; QUINOLONES;

EID: 84925959542     PISSN: 10766294     EISSN: 19318448     Source Type: Journal    
DOI: 10.1089/mdr.2014.0150     Document Type: Article

References (37)

1. Aathithan, S. , and G. L. French. 2011. Prevalence and role of efflux pump activity in ciprofloxacin resistance in clinical isolates of Klebsiella pneumoniae. Eur J Clin Microbiol Infect Dis. 30:745-752.
2. Bedenic, B. , A. Mazzariol, V. Plecko, Z. Bosnjak, P. Barl, J. Vranes, and G. Cornaglia. 2012. First report of KPC-producing Klebsiella pneumoniae in Croatia. J Chemother. 24:237-239.
3. Bialek-Davenet, S. , V. Leflon-Guibout, O. Tran Minh, E. Marcon, R. Moreau, and M. H. Nicolas-Chanoine. 2013. Complete deletion of the ramR gene in an in vitroselected mutant of Klebsiella pneumoniae overexpressing the AcrAB efflux pump. Antimicrob Agents Chemother. 57:672-673.
4. Brisse, S. , and J. Verhoef. 2001. Phylogenetic diversity of Klebsiella pneumoniae and Klebsiella oxytoca clinical isolates revealed by randomly amplified polymorphic DNA, gyrA and parC genes sequencing and automated ribotyping. Int J Syst Evol Microbiol. 51:915-924.
5. Carattoli, A. , A. Bertini, L. Villa, V. Falbo, K. L. Hopkins, and E. J. Threlfall. 2005. Identification of plasmids by PCR-based replicon typing. J Microbiol Methods. 63:219-228.
6. Cattoir, V. , L. Poirel, V. Rotimi, C. J. Soussy, and P. Nordmann. 2007. Multiplex PCR for detection of plasmidmediated quinolone resistance qnr genes in ESBL-producing enterobacterial isolates. J Antimicrob Chemother. 60: 394-397.
7. Cavaco, L. M. , H. Hasman, S. Xia, and F. M. Aarestrup. 2009. qnrD, a novel gene conferring transferable quinolone resistance in Salmonella enterica serovar Kentucky and Bovismorbificans strains of human origin. Antimicrob Agents Chemother. 53:603-608.
8. Chanawong, A. , F. H. M'Zali, J. Heritage, J. H. Xiong, and P. M. Hawkey. 2002. Three cefotaximases, CTX-M-9, CTX-M-13, and CTX-M-14, among Enterobacteriaceae in the People's Republic of China. Antimicrob Agents Chemother. 46:630-637.
9. Clinical Laboratory and Standards Institute. 2009. Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically: Approved Standard-Eighth Edition M07-A8. CLSI, Wayne, PA, USA.
10. Clinical Laboratory and Standards Institute. 2010. Performance Standards for Antimicrobial Susceptibility Testing: Twentieth Informational Supplement CLSI M100-S20. CLSI, Wayne, PA, USA.
11. Damjanova, I. , A. Toth, J. Paszti, G. Hajbel-Vekony, M. Jakab, J. Berta, H. Milch, and M. Fuzi. 2008. Expansion and countrywide dissemination of ST11, ST15 and ST147 ciprofloxacin-resistant CTX-M-15-type b-lactamase-producing Klebsiella pneumoniae epidemic clones in Hungary in 2005\-The new 'MRSAs'? J Antimicrob Chemother. 62: 978-985.
12. Falagas, M. E. , A. C. Kastoris, A. M. Kapaskelis, and D. E. Karageorgopoulos. 2010. Fosfomycin for the treatment of multidrug-resistant, including extended-spectrum b-lactamase producing, Enterobacteriaceae infections: a systematic review. Lancet Infect Dis. 10:43-50.
13. Garau, J. , M. Xercavins, M. Rodriguez-Carballeira, J. R. Gomez-Vera, I. Coll, D. Vidal, T. Llovet, and A. Ruiz-Bremon. 1999. Emergence and dissemination of quinolone-resistant Escherichia coli in the community. Antimicrob Agents Chemother. 43:2736-2741.
14. Giske, C. G. , I. Froding, C. M. Hasan, A. Turlej-Rogacka, M. Toleman, D. Livermore, N. Woodford, and T. R. Walsh. 2012. Diverse sequence types of Klebsiella pneumoniae contribute to the dissemination of blaNDM-1 in India, Sweden, and the United Kingdom. Antimicrob Agents Chemother. 56:2735-2738.
15. Illiaquer, M. , N. Caroff, P. Bemer, G. G. Aubin, M. E. Juvin, D. Lepelletier, A. Reynaud, and S. Corvec. 2012. Occurrence and molecular characterization of Klebsiella pneumoniae ST37 clinical isolates producing plasmidmediated AmpC recovered over a 3-year period. Diagn Microbiol Infect Dis. 74:95-97.
16. Johnson, J. R. , B. Johnston, C. Clabots, M. A. Kuskowski, S. Pendyala, C. Debroy, B. Nowicki, and J. Rice. 2010. Escherichia coli sequence type ST131 as an emerging fluoroquinolone-resistant uropathogen among renal transplant recipients. Antimicrob Agents Chemother. 54: 546-550.
17. Johnson, J. R. , M. Menard, B. Johnston, M. A. Kuskowski, K. Nichol, and G. G. Zhanel. 2009. Epidemic clonal groups of Escherichia coli as a cause of antimicrobial-resistant urinary tract infections in Canada, 2002 to 2004. Antimicrob Agents Chemother. 53:2733-2739.
18. Kado, C. I. , and S. T. Liu. 1981. Rapid procedure for detection and isolation of large and small plasmids. J Bacteriol. 145:1365-1373.
19. Kitchel, B. , J. K. Rasheed, J. B. Patel, A. Srinivasan, S. Navon-Venezia, Y. Carmeli, A. Brolund, and C. G. Giske. 2009. Molecular epidemiology of KPC-producing Klebsiella pneumoniae isolates in the United States: clonal expansion of multilocus sequence type 258. Antimicrob Agents Chemother. 53:3365-3370.
20. Ling, T. K. , J. Xiong, Y. Yu, C. C. Lee, H. Ye, and P. M. Hawkey. 2006. Multicenter antimicrobial susceptibility survey of gram-negative bacteria isolated from patients with community-acquired infections in the People's Republic of China. Antimicrob Agents Chemother. 50:374-378.
21. Livermore, D. M. 2009. Has the era of untreatable infections arrived? J Antimicrob Chemother. 64 Suppl 1:i29-i36.
22. Livermore, D. M. , M. Warner, S. Mushtaq, M. Doumith, J. Zhang, and N. Woodford. 2011. What remains against carbapenem-resistant Enterobacteriaceae? Evaluation of chloramphenicol, ciprofloxacin, colistin, fosfomycin, minocycline, nitrofurantoin, temocillin and tigecycline. Int J Antimicrob Agents. 37:415-419.
23. Nicolas-Chanoine, M. H. , J. Blanco, V. Leflon-Guibout, R. Demarty, M. P. Alonso, M. M. Canica, Y. J. Park, J. P. Lavigne, J. Pitout, and J. R. Johnson. 2008. Intercontinental emergence of Escherichia coli clone O25:H4-ST131 producing CTX-M-15. J Antimicrob Chemother. 61:273-281.
24. Paltansing, S. , M. E. Kraakman, J. M. Ras, E. Wessels, and A. T. Bernards. 2013. Characterization of fluoroquinolone and cephalosporin resistance mechanisms in Enterobacteriaceae isolated in a Dutch teaching hospital reveals the presence of an Escherichia coli ST131 clone with a specific mutation in parE. J Antimicrob Chemother. 68:40-45.
25. Park, C. H. , A. Robicsek, G. A. Jacoby, D. Sahm, and D. C. Hooper. 2006. Prevalence in the United States of aac(6¢)-Ib-cr encoding a ciprofloxacin-modifying enzyme. Antimicrob Agents Chemother. 50:3953-3955.
26. Peirano, G. , J. H. Sang, A. Pitondo-Silva, K. B. Laupland, and J. D. Pitout. 2012. Molecular epidemiology of extended-spectrum-b-lactamase-producing Klebsiella pneumoniae over a 10 year period in Calgary, Canada. J Antimicrob Chemother. 67:1114-1120.
27. Perez-Perez, F. J. , and N. D. Hanson. 2002. Detection of plasmid-mediated AmpC b-lactamase genes in clinical isolates by using multiplex PCR. J Clin Microbiol. 40: 2153-2162.
28. Rogers, B. A. , H. E. Sidjabat, and D. L. Paterson. 2011. Escherichia coli O25b-ST131: a pandemic, multiresistant, community-associated strain. J Antimicrob Chemother. 66:1-14.
29. Shibata, N. , H. Kurokawa, Y. Doi, T. Yagi, K. Yamane, J. Wachino, S. Suzuki, K. Kimura, S. Ishikawa, H. Kato, et al. 2006. PCR classification of CTX-M-type b-lactamase genes identified in clinically isolated gram-negative bacilli in Japan. Antimicrob Agents Chemother. 50:791-795.
30. Suzuki, S. , N. Shibata, K. Yamane, J. Wachino, K. Ito, and Y. Arakawa. 2009. Change in the prevalence of extended-spectrum-b-lactamase-producing Escherichia coli in Japan by clonal spread. J Antimicrob Chemother. 63: 72-79.
31. Swick, M. C. , S. K. Morgan-Linnell, K. M. Carlson, and L. Zechiedrich. 2011. Expression of multidrug efflux pump genes acrAB-tolC, mdfA, and norE in Escherichia coli clinical isolates as a function of fluoroquinolone and multidrug resistance. Antimicrob Agents Chemother. 55:921-924.
32. Tenover, F. C. , R. D. Arbeit, R. V. Goering, P. A. Mickelsen, B. E. Murray, D. H. Persing, and B. Swaminathan. 1995. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol. 33:2233-2239.
33. Voulgari, E. , O. Zarkotou, K. Ranellou, D. E. Karageorgopoulos, G. Vrioni, V. Mamali, K. Themeli-Digalaki, and A. Tsakris. 2013. Outbreak of OXA-48 carbapenemase-producing Klebsiella pneumoniae in Greece involving an ST11 clone. J Antimicrob Chemother. 68:84-88.
34. Wang, M. , Q. Guo, X. Xu, X. Wang, X. Ye, S. Wu, D. C. Hooper, and M. Wang. 2009. New plasmid-mediated quinolone resistance gene, qnrC, found in a clinical isolate of Proteus mirabilis. Antimicrob Agents Chemother. 53:1892-1897.
35. Woodford, N. , J. F. Turton, and D. M. Livermore. 2011. Multiresistant Gram-negative bacteria: the role of high-risk clones in the dissemination of antibiotic resistance. FEMS Microbiol Rev. 35:736-755.
36. Yagi, T. , H. Kurokawa, N. Shibata, K. Shibayama, and Y. Arakawa. 2000. A preliminary survey of extendedspectrum b-lactamases (ESBLs) in clinical isolates of Klebsiella pneumoniae and Escherichia coli in Japan. FEMS Microbiol Lett. 184:53-56.
37. Yamane, K. , J. Wachino, S. Suzuki, and Y. Arakawa. 2008. Plasmid-mediated qepA gene among Escherichia coli clinical isolates from Japan. Antimicrob Agents Chemother. 52: 1564-1566.