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Volumn 31, Issue 11, 2014, Pages 1293-1300

Efficacy and safety of dipeptidyl peptidase-4 inhibitors as an add-on to insulin treatment in patients with type 2 diabetes: A review

Author keywords

[No Author keywords available]

Indexed keywords

ALOGLIPTIN; DIPEPTIDYL PEPTIDASE IV INHIBITOR; HEMOGLOBIN A1C; INSULIN; LINAGLIPTIN; METFORMIN; PIOGLITAZONE; PLACEBO; SAXAGLIPTIN; SITAGLIPTIN; VILDAGLIPTIN; ANTIDIABETIC AGENT;

EID: 84925939838     PISSN: 07423071     EISSN: 14645491     Source Type: Journal    
DOI: 10.1111/dme.12561     Document Type: Review
Times cited : (15)

References (37)
  • 1
    • 77955657267 scopus 로고    scopus 로고
    • Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing link
    • DeFronzo RA. Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009. Diabetologia 2010; 53: 1270-1287.
    • (2010) The Claude Bernard Lecture 2009. Diabetologia , vol.53 , pp. 1270-1287
    • DeFronzo, R.A.1
  • 2
    • 0032983666 scopus 로고    scopus 로고
    • Glycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus: progressive requirement for multiple therapies (UKPDS 49). UK Prospective Diabetes Study (UKPDS) Group
    • Turner RC, Cull CA, Frighi V, Holman RR. Glycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus: progressive requirement for multiple therapies (UKPDS 49). UK Prospective Diabetes Study (UKPDS) Group. JAMA 1999; 281: 2005-2012.
    • (1999) JAMA , vol.281 , pp. 2005-2012
    • Turner, R.C.1    Cull, C.A.2    Frighi, V.3    Holman, R.R.4
  • 4
    • 1842855423 scopus 로고    scopus 로고
    • Incretins, insulin secretion and Type 2 diabetes mellitus
    • Vilsbøll T, Holst JJ. Incretins, insulin secretion and Type 2 diabetes mellitus. Diabetologia 2004; 47: 357-366.
    • (2004) Diabetologia , vol.47 , pp. 357-366
    • Vilsbøll, T.1    Holst, J.J.2
  • 5
    • 0022617246 scopus 로고
    • Reduced incretin effect in type 2 (non-insulin-dependent) diabetes
    • Nauck M, Stöckmann F, Ebert R, Creutzfeldt W. Reduced incretin effect in type 2 (non-insulin-dependent) diabetes. Diabetologia 1986; 29: 46-52.
    • (1986) Diabetologia , vol.29 , pp. 46-52
    • Nauck, M.1    Stöckmann, F.2    Ebert, R.3    Creutzfeldt, W.4
  • 6
    • 57649234120 scopus 로고    scopus 로고
    • The incretin system and its role in type 2 diabetes mellitus
    • Holst JJ, Vilsbøll T, Deacon CF. The incretin system and its role in type 2 diabetes mellitus. Mol Cell Endocrinol 2009; 297: 127-136.
    • (2009) Mol Cell Endocrinol , vol.297 , pp. 127-136
    • Holst, J.J.1    Vilsbøll, T.2    Deacon, C.F.3
  • 8
    • 53849095733 scopus 로고    scopus 로고
    • Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials
    • Madsbad S, Krarup T, Deacon CF, Holst JJ. Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials. Curr Opin Clin Nutr Metab Care 2008; 11: 491-499.
    • (2008) Curr Opin Clin Nutr Metab Care , vol.11 , pp. 491-499
    • Madsbad, S.1    Krarup, T.2    Deacon, C.F.3    Holst, J.J.4
  • 9
    • 34249868446 scopus 로고    scopus 로고
    • Dipeptidyl peptidase-4 inhibitors: clinical data and clinical implications
    • Ahrén B. Dipeptidyl peptidase-4 inhibitors: clinical data and clinical implications. Diabetes Care 2007; 30: 1344-1350.
    • (2007) Diabetes Care , vol.30 , pp. 1344-1350
    • Ahrén, B.1
  • 10
    • 34248223285 scopus 로고    scopus 로고
    • Biology of incretins: GLP-1 and GIP
    • Baggio LL, Drucker DJ. Biology of incretins: GLP-1 and GIP. Gastroenterology 2007; 132: 2131-2157.
    • (2007) Gastroenterology , vol.132 , pp. 2131-2157
    • Baggio, L.L.1    Drucker, D.J.2
  • 11
    • 78649686908 scopus 로고    scopus 로고
    • Dipeptidyl peptidase-4 inhibitors in the treatment of type 2 diabetes: a comparative review
    • Deacon CF. Dipeptidyl peptidase-4 inhibitors in the treatment of type 2 diabetes: a comparative review. Diabetes Obes Metab 2011; 13: 7-18.
    • (2011) Diabetes Obes Metab , vol.13 , pp. 7-18
    • Deacon, C.F.1
  • 12
    • 0031690479 scopus 로고    scopus 로고
    • Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes
    • Holst JJ, Deacon CF. Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes. Diabetes 1998; 47: 1663-1670.
    • (1998) Diabetes , vol.47 , pp. 1663-1670
    • Holst, J.J.1    Deacon, C.F.2
  • 13
    • 78649686908 scopus 로고    scopus 로고
    • Dipeptidyl peptidase-4 inhibitors in the treatment of type 2 diabetes: a comparative review
    • Deacon CF. Dipeptidyl peptidase-4 inhibitors in the treatment of type 2 diabetes: a comparative review. Diabetes Obes Metab 2011; 13: 7-18.
    • (2011) Diabetes Obes Metab , vol.13 , pp. 7-18
    • Deacon, C.F.1
  • 14
    • 84859721063 scopus 로고    scopus 로고
    • DPP-4 inhibitors in the management of type 2 diabetes: a critical review of head-to-head trials
    • Scheen AJ. DPP-4 inhibitors in the management of type 2 diabetes: a critical review of head-to-head trials. Diabetes Metab 2012; 38: 89-101.
    • (2012) Diabetes Metab , vol.38 , pp. 89-101
    • Scheen, A.J.1
  • 15
    • 84856452247 scopus 로고    scopus 로고
    • Dipeptidyl peptidase-4 (DPP-4) inhibitors are favourable to glucagon-like peptide-1 (GLP-1) agonists: no
    • Madsbad S. Dipeptidyl peptidase-4 (DPP-4) inhibitors are favourable to glucagon-like peptide-1 (GLP-1) agonists: no. Eur J Intern Med 2012; 23: 132-136.
    • (2012) Eur J Intern Med , vol.23 , pp. 132-136
    • Madsbad, S.1
  • 17
    • 0034819464 scopus 로고    scopus 로고
    • Combination therapies with insulin in type 2 diabetes
    • Yki-Järvinen H. Combination therapies with insulin in type 2 diabetes. Diabetes Care 2001; 24: 758-767.
    • (2001) Diabetes Care , vol.24 , pp. 758-767
    • Yki-Järvinen, H.1
  • 18
    • 33646110527 scopus 로고    scopus 로고
    • Addition of rapid-acting insulin to basal insulin therapy in type 2 diabetes: indications and modalities
    • Monnier L, Colette C. Addition of rapid-acting insulin to basal insulin therapy in type 2 diabetes: indications and modalities. Diabetes Metab 2006; 32: 7-13.
    • (2006) Diabetes Metab , vol.32 , pp. 7-13
    • Monnier, L.1    Colette, C.2
  • 19
    • 70450173642 scopus 로고    scopus 로고
    • Alogliptin added to insulin therapy in patients with type 2 diabetes reduces HbA(1C) without causing weight gain or increased hypoglycaemia
    • Rosenstock J, Rendell MS, Gross JL, Fleck PR, Wilson CA, Mekki Q. Alogliptin added to insulin therapy in patients with type 2 diabetes reduces HbA(1C) without causing weight gain or increased hypoglycaemia. Diabetes Obes Metab 2009; 11: 1145-1152.
    • (2009) Diabetes Obes Metab , vol.11 , pp. 1145-1152
    • Rosenstock, J.1    Rendell, M.S.2    Gross, J.L.3    Fleck, P.R.4    Wilson, C.A.5    Mekki, Q.6
  • 20
    • 84885130771 scopus 로고    scopus 로고
    • Saxagliptin Add-on Therapy to Insulin With or Without Metformin for Type 2 Diabetes Mellitus: 52-Week Safety and Efficacy
    • Barnett AH, Charbonnel B, Li J, Donovan M, Fleming D, Iqbal N. Saxagliptin Add-on Therapy to Insulin With or Without Metformin for Type 2 Diabetes Mellitus: 52-Week Safety and Efficacy. Clin Drug Investig 2013; 33: 707-717.
    • (2013) Clin Drug Investig , vol.33 , pp. 707-717
    • Barnett, A.H.1    Charbonnel, B.2    Li, J.3    Donovan, M.4    Fleming, D.5    Iqbal, N.6
  • 21
    • 84859731126 scopus 로고    scopus 로고
    • Effect of saxagliptin as add-on therapy in patients with poorly controlled type 2 diabetes on insulin alone or insulin combined with metformin
    • Barnett AH, Charbonnel B, Donovan M, Fleming D, Chen R. Effect of saxagliptin as add-on therapy in patients with poorly controlled type 2 diabetes on insulin alone or insulin combined with metformin. Curr Med Res Opin 2012; 28: 513-523.
    • (2012) Curr Med Res Opin , vol.28 , pp. 513-523
    • Barnett, A.H.1    Charbonnel, B.2    Donovan, M.3    Fleming, D.4    Chen, R.5
  • 22
    • 84925937959 scopus 로고    scopus 로고
    • Efficacy and safety of saxagliptin in combination with insulin in elderly patients with type 2 diabetes
    • Poster A.D.A 2012, 1048-P, Philadelphia, P.A., U.S.A.
    • Charbonnel B, Barnett AH, Monyak J, Minervini G, Iqbal N. Efficacy and safety of saxagliptin in combination with insulin in elderly patients with type 2 diabetes. Poster ADA 2012, 1048-P, Philadelphia, PA, USA, 2012.
    • (2012)
    • Charbonnel, B.1    Barnett, A.H.2    Monyak, J.3    Minervini, G.4    Iqbal, N.5
  • 23
    • 73349119110 scopus 로고    scopus 로고
    • Efficacy and safety of sitagliptin when added to insulin therapy in patients with type 2 diabetes
    • Vilsbøll T, Rosenstock J, Yki-Järvinen H, Cefalu WT, Chen Y, Luo E, et al. Efficacy and safety of sitagliptin when added to insulin therapy in patients with type 2 diabetes. Diabetes Obes Metab 2010; 12: 167-177.
    • (2010) Diabetes Obes Metab , vol.12 , pp. 167-177
    • Vilsbøll, T.1    Rosenstock, J.2    Yki-Järvinen, H.3    Cefalu, W.T.4    Chen, Y.5    Luo, E.6
  • 24
    • 84925956935 scopus 로고    scopus 로고
    • Effects of Adding linagliptin to basal insulin regimen for inadequately controlled type 2 diabetes: a = 52-week randomized, double-blind study
    • Yki-Järvinen H, Rosenstock J, Durán-Garcia S, Pinnetti S, Bhattacharya S, Thiemann S, et al. Effects of Adding linagliptin to basal insulin regimen for inadequately controlled type 2 diabetes: a = 52-week randomized, double-blind study. Diabetes Care 2013; 23: 1-7.
    • (2013) Diabetes Care , vol.23 , pp. 1-7
    • Yki-Järvinen, H.1    Rosenstock, J.2    Durán-Garcia, S.3    Pinnetti, S.4    Bhattacharya, S.5    Thiemann, S.6
  • 25
  • 26
    • 84873873967 scopus 로고    scopus 로고
    • Improved glycaemic control with vildagliptin added to insulin, with or without metformin, in patients with type 2 diabetes mellitus
    • Kothny W, Foley J, Kozlovski P, Shao Q, Gallwitz B, Lukashevich V. Improved glycaemic control with vildagliptin added to insulin, with or without metformin, in patients with type 2 diabetes mellitus. Diabetes Obes Metab 2013; 15: 252-257.
    • (2013) Diabetes Obes Metab , vol.15 , pp. 252-257
    • Kothny, W.1    Foley, J.2    Kozlovski, P.3    Shao, Q.4    Gallwitz, B.5    Lukashevich, V.6
  • 27
    • 65249095686 scopus 로고    scopus 로고
    • Vildagliptin enhances islet responsiveness to both hyper-and hypoglycemia in patients with type 2 diabetes
    • Ahrén B, Schweizer A, Dejager S, Dunning BE, Nilsson PM, Persson M, et al. Vildagliptin enhances islet responsiveness to both hyper-and hypoglycemia in patients with type 2 diabetes. J Clin Endocrinol Metab 2009; 94: 1236-1243.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 1236-1243
    • Ahrén, B.1    Schweizer, A.2    Dejager, S.3    Dunning, B.E.4    Nilsson, P.M.5    Persson, M.6
  • 28
    • 77955456705 scopus 로고    scopus 로고
    • Pharmacokinetics of dipeptidylpeptidase-4 inhibitors
    • Scheen AJ. Pharmacokinetics of dipeptidylpeptidase-4 inhibitors. Diabetes Obes Metab 2010; 12: 648-658.
    • (2010) Diabetes Obes Metab , vol.12 , pp. 648-658
    • Scheen, A.J.1
  • 29
    • 84859977229 scopus 로고    scopus 로고
    • Comparison of metformin and insulin versus insulin alone for type 2 diabetes: systematic review of randomised clinical trials with meta-analyses and trial sequential analyses
    • Hemmingsen B, Christensen LL, Wetterslev J, Vaag A, Gluud C, Lund SS, et al. Comparison of metformin and insulin versus insulin alone for type 2 diabetes: systematic review of randomised clinical trials with meta-analyses and trial sequential analyses. BMJ 2012; 344: e1771.
    • (2012) BMJ , vol.344
    • Hemmingsen, B.1    Christensen, L.L.2    Wetterslev, J.3    Vaag, A.4    Gluud, C.5    Lund, S.S.6
  • 30
    • 38149077951 scopus 로고    scopus 로고
    • Metformin and body weight
    • Golay A. Metformin and body weight. Int J Obes (Lond) 2008; 32: 61-72.
    • (2008) Int J Obes (Lond) , vol.32 , pp. 61-72
    • Golay, A.1
  • 31
    • 0026318073 scopus 로고
    • Insulin plus a sulfonylurea agent for treating type 2 diabetes
    • Peters AL, Davidson MB. Insulin plus a sulfonylurea agent for treating type 2 diabetes. Ann Intern Med 1991; 115: 45-53.
    • (1991) Ann Intern Med , vol.115 , pp. 45-53
    • Peters, A.L.1    Davidson, M.B.2
  • 32
    • 0031850906 scopus 로고    scopus 로고
    • Beginning insulin treatment of obese patients with evening 70/30 insulin plus glimepiride versus insulin alone
    • Riddle MC, Schneider J. Beginning insulin treatment of obese patients with evening 70/30 insulin plus glimepiride versus insulin alone. Glimepiride Combination Group. Diabetes Care 1998; 21: 1052-1057.
    • (1998) Glimepiride Combination Group. Diabetes Care , vol.21 , pp. 1052-1057
    • Riddle, M.C.1    Schneider, J.2
  • 33
    • 0344304678 scopus 로고    scopus 로고
    • Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Associati
    • Nesto RW, Bell D, Bonow RO, Fonseca V, Grundy SM, Horton ES, et al. Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Association. October 7, 2003. Circulation 2003; 108: 2941-2948.
    • (2003) October 7, 2003. Circulation , vol.108 , pp. 2941-2948
    • Nesto, R.W.1    Bell, D.2    Bonow, R.O.3    Fonseca, V.4    Grundy, S.M.5    Horton, E.S.6
  • 34
    • 34648832073 scopus 로고    scopus 로고
    • Congestive heart failure and cardiovascular death in patients with prediabetes and type 2 diabetes given thiazolidinediones: a meta-analysis of randomised clinical trials
    • Lago RM, Singh PP, Nesto RW. Congestive heart failure and cardiovascular death in patients with prediabetes and type 2 diabetes given thiazolidinediones: a meta-analysis of randomised clinical trials. Lancet 2007; 370: 1129-1136.
    • (2007) Lancet , vol.370 , pp. 1129-1136
    • Lago, R.M.1    Singh, P.P.2    Nesto, R.W.3
  • 35
    • 77955788270 scopus 로고    scopus 로고
    • Pioglitazone and the risk of cardiovascular events in patients with Type 2 diabetes receiving concomitant treatment with nitrates, renin-angiotensin system blockers, or insulin: results from the PROactive study (PROactive 20)
    • Erdmann E, Spanheimer R, Charbonnel B. Pioglitazone and the risk of cardiovascular events in patients with Type 2 diabetes receiving concomitant treatment with nitrates, renin-angiotensin system blockers, or insulin: results from the PROactive study (PROactive 20). J Diabetes 2010; 2: 212-220.
    • (2010) J Diabetes , vol.2 , pp. 212-220
    • Erdmann, E.1    Spanheimer, R.2    Charbonnel, B.3
  • 36
    • 79551615182 scopus 로고    scopus 로고
    • Use of twice-daily exenatide in Basal insulin-treated patients with type 2 diabetes: a randomized, controlled trial
    • Buse JB, Bergenstal RM, Glass LC, Heilmann CR, Lewis MS, Kwan AYM, et al. Use of twice-daily exenatide in Basal insulin-treated patients with type 2 diabetes: a randomized, controlled trial. Ann Intern Med 2011; 154: 103-112.
    • (2011) Ann Intern Med , vol.154 , pp. 103-112
    • Buse, J.B.1    Bergenstal, R.M.2    Glass, L.C.3    Heilmann, C.R.4    Lewis, M.S.5    Kwan, A.Y.M.6
  • 37
    • 79959428521 scopus 로고    scopus 로고
    • Safety, efficacy and tolerability of exenatide in combination with insulin in the Association of British Clinical Diabetologists nationwide exenatide audit
    • Thong KY, Jose B, Sukumar N, Cull ML, Mills AP, Sathyapalan T, et al. Safety, efficacy and tolerability of exenatide in combination with insulin in the Association of British Clinical Diabetologists nationwide exenatide audit. Diabetes Obes Metab 2011; 13: 703-710.
    • (2011) Diabetes Obes Metab , vol.13 , pp. 703-710
    • Thong, K.Y.1    Jose, B.2    Sukumar, N.3    Cull, M.L.4    Mills, A.P.5    Sathyapalan, T.6


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