Assessing Pseudomonas aeruginosa virulence and the host response using Murine models of acute and chronic lung infection

Methods in Molecular Biology

Volumn 1149, Issue , 2014, Pages 757-771

  Kukavica Ibrulj, Irena ^a   Facchini, Marcella ^a   Cigana, Cristina ^a   Levesque, Roger C ^a   Bragonzi, Alessandra ^a  

^a NONE

Author keywords

Acute; Chronic; Cystic fibrosis; Lung infection; Murine models; Pneumonia; Pseudomonas aeruginosa

Indexed keywords

ACUTE DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL LOAD; BACTERIAL VIRULENCE; CHRONIC DISEASE; COLONY FORMING UNIT; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GROWTH CURVE; HISTOPATHOLOGY; IMMUNE RESPONSE; LUNG INFECTION; MALE; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; RAT; WEIGHT REDUCTION; ANIMAL; BACTERIAL COUNT; BIOASSAY; C57BL MOUSE; DISEASE MODEL; GROWTH, DEVELOPMENT AND AGING; HOST PATHOGEN INTERACTION; INFLAMMATION; KINETICS; LUNG; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY; PROCEDURES; PSEUDOMONAS INFECTION; RESPIRATORY TRACT INFECTION; SPRAGUE DAWLEY RAT; SURVIVAL; VIRULENCE;

BACTERIA (MICROORGANISMS); MURINAE; PSEUDOMONAS AERUGINOSA; RATTUS;

AGAR;

ACUTE DISEASE; AGAR; ANIMALS; BIOLOGICAL ASSAY; CHRONIC DISEASE; COLONY COUNT, MICROBIAL; DISEASE MODELS, ANIMAL; HOST-PATHOGEN INTERACTIONS; INFLAMMATION; KINETICS; LUNG; MALE; MICE, INBRED C57BL; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; RATS, SPRAGUE-DAWLEY; RESPIRATORY TRACT INFECTIONS; SURVIVAL ANALYSIS; VIRULENCE;

EID: 84925883898     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4939-0473-0_58     Document Type: Article

References (28)

1. Bianconi I et al (2011) Positive signaturetagged mutagenesis in Pseudomonas aeruginosa: tracking patho-adaptive mutations promoting airways chronic infection. PLoS Pathog 7:e1001270
2. Dunn MM, Toews GB, Hart D, Pierce AK (1985) The effects of systemic immunization of pulmonary clearance of Pseudomonas aeruginosa. Am Rev Respir Dis 131:426–431
3. Lore NI et al (2012) Cystic fibrosis-niche adaptation of Pseudomonas aeruginosa reduces virulence in multiple infection hosts. PLoS ONE 7:e35648
4. Schook LB, Carrick L Jr, Berk RS (1977) Experimental pulmonary infection of mice by tracheal intubation of Pseudomonas aeruginosa: the use of antineoplastic agents to overcome natural resistance. Can J Microbiol 23: 823–826
5. Yu H, Hanes M, Chrisp CE, Boucher JC, Deretic V (1998) Microbial pathogenesis in cystic fibrosis: pulmonary clearance of mucoid Pseudomonas aeruginosa and inflammation in a mouse model of repeated respiratory challenge. Infect Immun 66:280–288
6. McCray PB Jr, Zabner J, Jia HP, Welsh MJ, Thorne PS (1999) Efficient killing of inhaled bacteria in DeltaF508 mice: role of airway surface liquid composition. Am J Physiol 277: L183–L190
7. Cash HA, Woods DE, McCullough B, Johanson WG Jr, Bass JA (1979) A rat model of chronic respiratory infection with Pseudo monas aeruginosa. Am Rev Respir Dis 119:453–459
8. Klinger JD, Cash HA, Wood RE, Miler JJ (1983) Protective immunization against chronic Pseudomonas aeruginosa pulmonary infection in rats. Infect Immun 39:1377–1384
9. Bragonzi A et al (2006) Sequence diversity of the mucABD locus in Pseudomonas aeruginosa isolates from patients with cystic fibrosis. Microbiology 152:3261–3269
10. Hoiby N et al (2001) Pseudomonas aeruginosa and the in vitro and in vivo biofilm mode of growth. Microbes Infect 3:23–35
11. Hodgson AE, Nelson SM, Brown MR, Gilbert PA (1995) Simple in vitro model for growth control of bacterial biofilms. J Appl Bacteriol 79:87–93
12. Rejman J et al (2010) Impact of chronic pulmonary infection with Pseudomonas aeruginosa on transfection mediated by viral and nonviral vectors. Hum Gene Ther 21:351–356
13. Cantin AM, Woods DE (1999) Aerosolized prolastin suppresses bacterial proliferation in a model of chronic Pseudomonas aeruginosa lung infection. Am J Respir Crit Care Med 160:1130–1135
14. Amano H et al (2000) Role of cytokine- induced neutrophil chemoattractant-2 (CINC- 2) alpha in a rat model of chronic bronchopulmonary infections with Pseudomonas aeruginosa. Cytokine 12:1662–1668
15. Omri A, Suntres ZE, Shek PN (2002) Enhanced activity of liposomal polymyxin B against Pseudomonas aeruginosa in a rat model of lung infection. Biochem Pharmacol 64: 1407–1413
16. Potvin E et al (2003) In vivo functional genomics of Pseudomonas aeruginosa for highthroughput screening of new virulence factors and antibacterial targets. Environ Microbiol 5:1294–1308
17. Duan K, Dammel C, Stein J, Rabin H, Surette MG (2003) Modulation of Pseudomonas aeruginosa gene expression by host microflora through interspecies communication. Mol Micro biol 50:1477–1491
18. Lehoux DE, Sanschagrin F, Kukavica-Ibrulj I, Potvin E, Levesque RC (2004) Identification of novel pathogenicity genes by PCR signaturetagged mutagenesis and related technologies. Methods Mol Biol 266:289–304
19. Joly B et al (2005) Relative expression of Pseudomonas aeruginosa virulence genes analyzed by a real time RT-PCR method during lung infection in rats. FEMS Microbiol Lett 243: 271–278
20. Woods DE, Cantin A, Cooley J, Kenney DM, Remold-O’Donnell E (2005) Aerosol treatment with MNEI suppresses bacterial proliferation in a model of chronic Pseudomonas aeruginosa lung infection. Pediatr Pulmonol 39:141–149
21. Zhang L et al (2005) Antimicrobial peptide therapeutics for cystic fibrosis. Antimicrob Agents Chemother 49:2921–2927
22. Boyer S et al (2005) Chronic pneumonia with P seudomonas aeruginosa and impaired alveolar fluid clearance. Respir Res 6:17
23. Kukavica-Ibrulj I, Levesque RC (2008) Animal models of chronic lung infection with Pseudomonas aeruginosa: useful tools for cystic fibrosis studies. Lab Anim 42:389–412
24. Lehoux DE, Sanschagrin F, Levesque RC (2000) Genomics of the 35-kb pvd locus and analysis of novel pvdIJK genes implicated in pyoverdine biosynthesis in Pseudomonas aeruginosa. FEMS Microbiol Lett 190: 141–146
25. Hava DL, Camilli A (2002) Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Mol Microbiol 45: 1389–1406
26. Kukavica-Ibrulj I et al (2008) In vivo growth of Pseudomonas aeruginosa strains PAO1 and PA14 and the hypervirulent strain LESB58 in a rat model of chronic lung infection. J Bacteriol 190:2804–2813
27. Winstanley C et al (2009) Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool epidemic strain of Pseudomonas aeruginosa. Genome Res 19:12–23
28. Bragonzi A (2010) Murine models of acute and chronic lung infection with cystic fibrosis pathogens. Int J Med Microbiol 300: 584–593