A targeted analysis identifies a high frequency of BRCA1 and BRCA2 mutation carriers in women with ovarian cancer from a founder population

Journal of Ovarian Research

Volumn 8, Issue 1, 2015, Pages

  Belanger, Moria H ^a   Dolman, Lena ^a   Arcand, Suzanna L ^b   Shen, Zhen ^c   Chong, George ^c   Mes Masson, Anne Marie ^d,e   Provencher, Diane ^d,e   Tonin, Patricia N ^a,b,f  

^a MCGILL UNIVERSITY   (Canada)

^b RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d UNIVERSITÉ DE MONTRÉAL   (Canada)

^e CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^f MONTREAL GENERAL HOSPITAL   (Canada)

Author keywords

BRCA1; BRCA2; Founder; French Canadian; Genetic testing; Mutation frequency; Ovarian cancer

Indexed keywords

ADENOCARCINOMA; ADULT; ARTICLE; CANCER GRADING; ENDOMETRIOID CARCINOMA; FEMALE; GENE FREQUENCY; GENE MUTATION; GENE TARGETING; GENETIC HETEROGENEITY; GENETIC SCREENING; HUMAN; MAJOR CLINICAL STUDY; MIDDLE AGED; MUTATION RATE; OVARY CANCER; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE; UNDIFFERENTIATED CARCINOMA; UTERINE TUBE CARCINOMA; FOUNDER EFFECT; GENETIC PREDISPOSITION; GENETICS; HETEROZYGOTE; MUTATION; NEOPLASM; OVARY TUMOR; QUEBEC;

FEMALE; FOUNDER EFFECT; GENES, BRCA1; GENES, BRCA2; GENETIC PREDISPOSITION TO DISEASE; HETEROZYGOTE; HUMANS; MUTATION; NEOPLASMS, GLANDULAR AND EPITHELIAL; OVARIAN NEOPLASMS; QUEBEC;

EID: 84925882236     PISSN: None     EISSN: 17572215     Source Type: Journal    
DOI: 10.1186/s13048-015-0124-8     Document Type: Article

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