Alcohol potentiates postburn remote organ damage through shifts in fluid compartments mediated by bradykinin

Shock

Volumn 43, Issue 1, 2015, Pages 80-84

  Chen, Michael M ^a,b,c   O'Halloran, Eileen B ^b,c   Ippolito, Jill A ^a,c   Choudhry, Mashkoor A ^a,b,c   Kovacs, Elizabeth J ^a,b,c  

^a Alcohol Research Program   (United States)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

^c LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

Ethanol; Intoxication; Ischemia; Third spacing; Trauma

Indexed keywords

ALCOHOL; BRADYKININ; CREATININE; ICATIBANT; BRADYKININ B2 RECEPTOR ANTAGONIST; CENTRAL DEPRESSANT AGENT;

ALCOHOL BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL TRANSLOCATION; BODY SURFACE; BODY WEIGHT; BURN; BURN PATIENT; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DEHYDRATION; FLUID BALANCE; FLUID RETENTION; FLUID SHIFT; HEMATOCRIT; LIVER WEIGHT; MALE; MESENTERY LYMPH NODE; MOUSE; MULTIPLE ORGAN FAILURE; NONHUMAN; POSTBURN REMOTE ORGAN DAMAGE; PREVALENCE; UREA NITROGEN BLOOD LEVEL; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; BURNS; COMPLICATION; DRUG EFFECTS; HUMAN; ISCHEMIA;

ANIMALS; BACTERIAL TRANSLOCATION; BRADYKININ; BRADYKININ B2 RECEPTOR ANTAGONISTS; BURNS; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CREATININE; DEHYDRATION; ETHANOL; HEMATOCRIT; HUMANS; ISCHEMIA; MALE; MICE;

EID: 84925871426     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0000000000000265     Document Type: Article

References (34)

1. Mokdad AH, Marks JS, Stroup DF, Gerberding JL: Actual causes of death in the United States, 2000. JAMA 291:1238-1245, 2004.
2. Hadjizacharia P, O'Keeffe T, Plurad DS, Green DJ, Brown CV, Chan LS, et al.: Alcohol exposure and outcomes in trauma patients. Eur J Trauma Emerg Surg 37:169-175, 2011.
3. Naimi TS, Brewer RD, Mokdad A, Denny C, Serdula MK, Marks JS: Binge drinking among US adults. JAMA 289:70-75, 2003.
4. Savola O, Niemela O, Hillbom M: Alcohol intake and the pattern of trauma in young adults and working aged people admitted after trauma. Alcohol Alcohol 40:269-273, 2005.
5. Thal ER, Bost RO, Anderson RJ: Effects of alcohol and other drugs on traumatized patients. Arch Surg 120:708-712, 1985.
6. Silver GM, Albright JM, Schermer CR, Halerz M, Conrad P, Ackerman PD, et al.: Adverse clinical outcomes associated with elevated blood alcohol levels at the time of burn injury. J Burn Care Res 29:784-789, 2008.
7. Brezel BS, Kassenbrock JM, Stein JM: Burns in substance abusers and in neu-rologically and mentally impaired patients. J Burn Care Rehabil 9:169-171, 1988.
8. American Burn Association: National Burn Repository: 2012 Report. Chicago, IL: American Burn Association, 2012.
9. Bird MD, Zahs A, Deburghgraeve C, Ramirez L, Choudhry MA, Kovacs EJ: Decreased pulmonary inflammation following ethanol and burn injury in mice deficient in TLR4 but not TLR2 signaling. Alcohol Clin Exp Res 34: 1733-1741, 2010.
10. Chen MM, Bird MD, Zahs A, Deburghgraeve C, Posnik B, Davis CS, et al.: Pulmonary inflammation after ethanol exposure and burn injury is attenuated in the absence of IL-6. Alcohol 47:223-229, 2013.
11. Murdoch EL, Brown HG, Gamelli RL, Kovacs EJ: Effects of ethanol on pulmonary inflammation in postburn intratracheal infection. J Burn Care Res 29: 323-330, 2008.
12. Biffl WL, Moore EE, Moore FA, Peterson VM: Interleukin-6 in the injured patient. Marker of injury or mediator of inflammation? Ann Surg 224:647-664, 1996.
13. Griffin R, Poe AM, Cross JM, Rue LW 3rd, McGwin G, Jr: The association between blood alcohol level and infectious complications among burn patients. J Burn Care Res 30:395-399, 2009.
14. Jarrar D, Chaudry IH, Wang P: Organ dysfunction following hemorrhage and sepsis: mechanisms and therapeutic approaches [review]. Int J Mol Med 4: 575-583, 1999.
15. Schroeder JE, Weiss YG, Mosheiff R: The current state in the evaluation and treatment of ARDS and SIRS. Injury 40(Suppl 4):S82-S89, 2009.
16. Tanaka Y, Yamashita Y: Effects of ethanol administration at a high-dose level on the stimulatory action by bradykinin in vascular permeability. J Nutr Sci Vitaminol (Tokyo) 48:270-277, 2002.
17. Ward PA, Till GO: Pathophysiologic events related to thermal injury of skin. J Trauma 30:S75-S79, 1990.
18. Faunce DE, Gregory MS, Kovacs EJ: Effects of acute ethanol exposure on cellular immune responses in a murine model of thermal injury. J Leukoc Biol 62:733-740, 1997.
19. Chen MM, Palmer JL, Ippolito JA, Curtis BJ, Choudhry MA, Kovacs EJ: Intoxication by intraperitoneal injection or oral gavage equally potentiates post-burn organ damage and inflammation. Mediators Inflamm 2013:971481, 2013.
20. Faunce DE, Llanas JN, Patel PJ, Gregory MS, Duffner LA, Kovacs EJ: Neu-trophil chemokine production in the skin following scald injury. Burns 25: 403-410, 1999.
21. Zahs A, Bird MD, Ramirez L, Choudhry MA, Kovacs EJ: Anti-IL-6 antibody treatment but not IL-6 knockout improves intestinal barrier function and reduces inflammation following binge ethanol exposure and burn injury. Shock 39(4):373-379, 2013.
22. Zahs A, Bird MD, Ramirez L, Turner JR, Choudhry MA, Kovacs EJ: Inhibition of long myosin light-chain kinase activation alleviates intestinal damage after binge ethanol exposure and burn injury. Am J Physiol Gastrointest Liver Physiol 303:G705-G712, 2012.
23. Patel PJ, Faunce DE, Gregory MS, Duffner LA, Kovacs EJ: Elevation in pulmonary neutrophils and prolonged production of pulmonary macrophage inflammatory protein-2 after burn injury with prior alcohol exposure. Am J Respir Cell Mol Biol 20:1229-1237, 1999.
24. Steinvall I, Bak Z, Sjoberg F: Acute respiratory distress syndrome is as important as inhalation injury for the development of respiratory dysfunction in major burns. Burns 34:441-451, 2008.
25. Wakabayashi I, Kato H: Alcohol abuse as a risk factor for ARDS [in Japanese]. Nihon Arukoru Yakubutsu Igakkai Zasshi 41:400-406, 2006.
26. Chen MM, Zahs A, Brown MM, Ramirez L, Turner JR, Choudhry MA, et al.: An alteration of the gut-liver axis drives pulmonary inflammation after intoxication and burn injury in mice. Am J Physiol Gastrointest Liver Physiol 37(7): G711-G718, 2014.
27. Jones WG 2nd, Minei JP, Barber AE, Fahey TJ 3rd, Shires GT 3rd, Shires GT: Splanchnic vasoconstriction and bacterial translocation after thermal injury. Am J Physiol 261:H1190-H1196, 1991.
28. Hall JM: Bradykinin receptors. Gen Pharmacol 28:1-6, 1997.
29. Barratt-Due A, Johansen HT, Sokolov A, Thorgersen EB, Hellerud BC, Reubsaet JL, et al.: The role of bradykinin and the effect of the bradykinin receptor antagonist icatibant in porcine sepsis. Shock 36:517-23, 2011.
30. Griesbacher T, Lembeck F: Effects of the bradykinin antagonist, HOE 140, in experimental acute pancreatitis. Br J Pharmacol 107:356-360, 1992.
31. Wirth KJ, Alpermann HG, Satoh R, Inazu M: The bradykinin antagonist Hoe 140 inhibits carrageenan-and thermically induced paw oedema in rats. Agents Actions Suppl 38(Pt 3):428-431, 1992.
32. Jonkam CC, Enkhbaatar P, Nakano Y, Boehm T, Wang J, Nussberger J, et al.: Effects of the bradykinin B2 receptor antagonist icatibant on microvascular permeability after thermal injury in sheep. Shock 28:704-709, 2007.
33. Rana SN, Li X, Chaudry IH, Bland KI, Choudhry MA: Inhibition of IL-18 reduces myeloperoxidase activity and prevents edema in intestine following alcohol and burn injury. J Leukoc Biol 77:719-728, 2005.
34. Nomellini V, Brubaker AL, Mahbub S, Palmer JL, Gomez CR, Kovacs EJ: Dysregulation of neutrophil CXCR2 and pulmonary endothelial icam-1 promotes age-related pulmonary inflammation. Aging Dis 3:234-247, 2012.