Targeted drug delivery system- formulation and evaluation of chitosan nanospheres containing doxorubicin hydrochloride

International Journal of Drug Delivery

Volumn 6, Issue 2, 2014, Pages 186-193

  Dhanaraj, Sokkalingam Arumugam ^a   Muralidharan, Selvadurai ^a   Santhi, Kumaraswamy ^a   Hui, Amanda Lim Sze ^a   Wen, Cheong Jia ^a   Teng, Hoh Chew ^a  

^a AIMST UNIVERSITY   (Malaysia)

Author keywords

Chitosan; Cytotoxicity; Doxorubicin; Naoparticles; Targeting

Indexed keywords

CHITOSAN NANOPARTICLE; DOXORUBICIN; GLUTARALDEHYDE; NANOSPHERE; SORBITAN OLEATE; TOLUENE;

ARTICLE; CALIBRATION; CENTRIFUGATION; DRUG FORMULATION; DRUG RELEASE; DRUG SCREENING; GEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KINETICS; SCANNING ELECTRON MICROSCOPY;

EID: 84925849103     PISSN: None     EISSN: 09750215     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Drugs.com. Rubex® (doxorubicin hydrochloride for injection, USP).
2. Qin Tian et al. Glycyrrhetinic acidmodified chitosan/poly(ethylene glycol) nanoparticles for liver-targeted delivery. Biomaterials 31.2010; 4748-4756.
3. Gupta Manish and Sharma Vimukta. Targeted drug delivery system: A Review; Research Journal of Chemical Sciences, 2011; 1 (2):135-138
4. Otilia M. Koo, Israel Rubinstein, Hayat Onyuksei. Role of nanotechnology in targeted drug delivery and imaging: a concise review. Nanomedicine: Nanotechnology, Biology and Medicine, 2005;1(3): 193-212.
5. VJ Mohanraj and Y Chen: Nanoparticles- A Review. Tropical Journal of Pharmaceutical Research, 2006; 5 (1): 561-573.
6. Wim H De Jong and Paul JA Borm. Drug delivery and nanoparticles: Applications and hazards Int J Nanomedicine. 2008; 3(2): 133-149.
7. Riddhi Dave and Rakesh Patel. Preparation and characterization of doxorubicin HCl loaded chitosan nanoparticles by w/o emulsion method. Int. J. of Pharm. & Life Sci.2013; 4(2): 2407-2413.
8. Komal Patel et al. Preparation and in vivo study of Doxorubicin HCl loaded chitosan nanoparticles prepared by w/o emulsion method. International Journal of Current Research. 2012; 4(12): 438-440.
9. Parichart Naruphontjirakul et al. Development of Doxorubicin – Core Shell Chitosan Nanoparticles to Treat Cancer. 2011;11:18-40