Does weight loss in overweight or obese women improve fertility treatment outcomes? A systematic review

Obesity Reviews

Volumn 15, Issue 10, 2014, Pages 839-850

  Sim, K A ^a   Partridge, S R ^a   Sainsbury, A ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Assisted reproductive technology; Obesity; Pregnancy; Weight loss

Indexed keywords

ARTICLE; BARIATRIC SURGERY; BEHAVIOR CHANGE; CALORIC INTAKE; CONCEPTION; CONSULTATION; DIET; EMBRYO TRANSFER; EVIDENCE BASED PRACTICE; EXERCISE; FEMALE FERTILITY; FOLLOW UP; HUMAN; INFERTILITY THERAPY; LIFESTYLE MODIFICATION; LIVE BIRTH; MENSTRUAL CYCLE; OBESITY; PATIENT EDUCATION; PRACTICE GUIDELINE; PREGNANCY OUTCOME; PREGNANCY RATE; RANDOMIZED CONTROLLED TRIAL (TOPIC); SPONTANEOUS ABORTION; SYSTEMATIC REVIEW; TREATMENT OUTCOME; WEIGHT REDUCTION; ADULT; FEMALE; LOW CALORY DIET; PREGNANCY; RISK REDUCTION;

ADULT; DIET, REDUCING; FEMALE; HUMANS; OBESITY; PREGNANCY; PREGNANCY OUTCOME; REPRODUCTIVE TECHNIQUES, ASSISTED; RISK REDUCTION BEHAVIOR; WEIGHT LOSS;

EID: 84925848849     PISSN: 14677881     EISSN: 1467789X     Source Type: Journal    
DOI: 10.1111/obr.12217     Document Type: Article

References (67)

1. Flegal KM, Carroll MD, Kit BK, Ogden CL. Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010. JAMA 2012; 307: 491-497.
2. Rich-Edwards J, Goldman MB, Willet WC et al. Adolescent body mass index and infertility caused by ovulatory disorder. Am J Obstet Gynaecol 1994; 171: 171-177.
3. Grodstein F, Goldman MB, Cramer DW. Body mass index and ovulatory infertility. Epidemiology 1994; 5: 247-250.
4. Jensen T, Scheike T, Keiding N, Schaumburg I, Grandjean P. Fecundability in relation to body mass and menstrual cycle patterns. Epidemiology 1999; 10: 422-428.
5. Gesink Law DC, Maclehose RF, Longnecker MP. Obesity and time to pregnancy. Hum Reprod 2007; 22: 414-420.
6. Ferraretti AP, Goossens V, Kupka M et al. Assisted reproductive technology in Europe, 2009: results generated from European registers by ESHRE. Hum Reprod 2013; 28: 2318-2331.
7. Cedergren M. Maternal morbid obesity and the risk of adverse pregnancy outcome. Obstet Gynecol 2004; 103: 219-224.
8. Linné Y. Effects of obesity on women's reproduction and complications during pregnancy. Obes Rev 2004; 5: 137-143.
9. Ramsay JE, Greer I, Sattar N. Obesity and reproduction. BMJ 2006; 333: 1159-1162.
10. Danielzik S, Langnase K, Mast M, Spethmann C, Muller MJ. Impact of parental BMI on the manifestation of overweight 5-7 years old children. Eur J Nutr 2002; 41: 132-138.
11. Shankar K, Harrell A, Liu X, Gilchrist JM, Ronis MJ, Badger TM. Maternal obesity at conception programs obesity in the offspring. Am J Physiol Regul Integr Comp Physiol 2008; 294: R528- R538.
12. Wu Q, Suzuki M. Parental obesity and overweight affect the body-fat accumulation in the offspring: the possible effect of a high-fat diet through epigenetic inheritance. Obes Rev 2006; 7: 201-208.
13. Koning AM, Mutsaerts MA, Kuchenbecker WK et al. Complications and outcome of assisted reproduction technologies in overweight and obese women. Hum Reprod 2012; 27: 457- 467.
14. Moragianni VA, Jones SM, Ryley DA. The effect of body mass index on the outcomes of first assisted reproductive technology cycles. Fertil Steril 2012; 98: 102-108.
15. Bellver J. Impact of bodyweight and lifestyle on IVF outcome. Expert Rev Obstet Gynecol 2008; 3: 607-625.
16. Hollmann M, Runnebaum B, Gerhard I. Effects of weight loss on the hormonal profile in obese, infertile women. Hum Reprod 1996; 11: 1884-1891.
17. Zegers-Hochschild F, Adamson GD, de Mouzon J et al. International Committee for Monitoring Assisted Reproductive Technology (ICMART) and the World Health Organization (WHO) revised glossary of ART terminology, 2009. Fertil Steril 2009; 92: 1520-1524.
18. World Health Organization. International Statistical Classification of Diseases and Related Health Problems, 10th edn. World Health Organization: Geneva, 1992.
19. World Health Organization. Obesity: Preventing and Managing the Global Epidemic. World Health Organization: Geneva, 2000.
20. National Collaborating Centre for Methods and Tools. Quality Assessment Tool for Quantitative Studies. McMaster University: Hamilton, ON, 2010.
21. Sim KA, Dezarnaulds GM, Denyer GS, Skilton MR, Caterson ID. Weight loss improves reproductive outcomes for obese women undergoing assisted reproductive technology: a randomised controlled trial. Clin Obes 2014; 14: 792-805.
22. Moran L, Tsagareli V, Norman R, Noakes M. Diet and IVF pilot study: short-term weight loss improves pregnancy rates in overweight/obese women undertaking IVF. Aust N Z J Obstet Gynaecol 2011; 51: 455-459.
23. Clark AM, Ledger W, Galletly C et al. Weight loss results in significant improvement in pregnancy and ovulation rates in anovulatory obese women. Hum Reprod 1995; 10: 2705-2712.
24. Clark AM, Thornley B, Tomlinson L, Galletley C, Norman RJ. Weight loss in obese infertile women results in improvement in reproductive outcome for all forms of fertility treatment. Hum Reprod 1998; 13: 1502-1505.
25. Galletly C, Clark A, Tomlinson L, Blaney F. A group program for obese, infertile women: weight loss and improved psychological health. J Psychosom Obstet Gynaecol 1996; 17: 125- 128.
26. van Veen LJ, van den Dool GC, Rijnsaardt HGM, Lambers MDA. The Development of a Life Style Program Aimed at Weight Reduction in Obese Patients with Subfertility in a Large District Hospital, Results After Five Years. European Society of Human Reproduction and Embryology: Stockholm, 2011.
27. Awartani KA, Al-Sahan N, Al-Hassan SH, Coskun S. Effect of weight loss in morbidly obese infertile women on IVF outcome. Fertil Steril 2012; 98: S204.
28. Tsagareli V, Noakes M, Norman RJ. Effect of a very-lowcalorie diet on in vitro fertilization outcomes. Fertil Steril 2006; 86: 227-229.
29. Musella M, Milone M, Bellini M et al. The potential role of intragastric balloon in the treatment of obese-related infertility: personal experience. Obes Surg 2011; 21: 426-430.
30. Doblado MA, Lewkowksi BM, Odem RR, Jungheim ES. In vitro fertilization after bariatric surgery. Fertil Steril 2010; 94: 2812-2814.
31. Hirshfeld-Cytron J, Kim HH. Empty follicle syndrome in the setting of dramatic weight loss after bariatric surgery: case report and review of available literature. Fertil Steril 2008; 90: 1199.
32. U.S. Food and Drug Administration. Xenical (orlistat) capsules. 2013. [WWW document]. URL http://www.accessdata.fda.gov/drugsatfda_docs/label/2010/020766s028lbl.pdf (accessed February 2014).
33. U.S. Food and Drug Administration. Qsymia (phentermine and topiramate extended-release) capsules. 2013. [WWW document]. URL http://www.fda.gov/downloads/drugs/drugsafety/ postmarketdrugsafetyinformationforpatientsandproviders/ ucm312598.pdf (accessed February 2014).
34. U.S. Food and Drug Administration. FDA approves Belviq to treat some overweight or obese adults. 2013. [WWW document]. URL http://www.fda.gov/newsevents/newsroom/ pressannouncements/ucm309993.htm accessed February 2014).
35. Olivius C, Friden B, Borg G, Bergh C. Why do couples discontinue in vitro fertilization treatment? A cohort study. Fertil Steril 2004; 81: 258-261.
36. O'Connor TM, O'Halloran DJ, Shanahan F. The stress response and the hypothalamic-pituitary-adrenal axis: from molecule to melancholia. QJM 2000; 93: 323-333.
37. Boivin J, Griffiths E, Venetis CA. Emotional distress in infertile women and failure of assisted reproductive technologies: metaanalysis of prospective psychosocial studies. BMJ 2011; 342: d223.
38. Domar AD, Seibel MM, Benson H. The mind/body program for infertility: a new behavioural treatment approach for women with infertility. Fertil Steril 1990; 53: 246-269.
39. Stewart DE, Boydell KM, McCarthy K, Swerdlyk S, Redmond C, Cohrs W. A prospective study of the effectiveness of brief professionally-led support groups for infertility patients. Int J Psychiatry Med 1992; 22: 173-182.
40. Rich-Edwards JW, Spiegelman D, Garland M et al. Physical activity, body mass index, and ovulatory disorder infertility. Epidemiology 2002; 13: 184-190.
41. Baker S, Jerums G, Proietto J. Effects and clinical potential of very-low-calorie diets (VLCDs) in type 2 diabetes. Diabetes Res Clin Pract 2009; 85: 235-242.
42. Chearskul S, Delbridge E, Shulkes A, Proietto J, Kriketos A. Effect of weight loss and ketosis on postprandial cholecystokinin and free fatty acid concentrations. Am J Clin Nutr 2008; 87: 1238-1246.
43. Delbridge E, Proietto J. State of the science: VLED (very low energy diet) for obesity. Asia Pac J Clin Nutr 2006; 15(Suppl.): 49-54.
44. Sainsbury A, Zhang L. Role of the hypothalamus in the neuroendocrine regulation of body weight and composition during energy deficit. Obes Rev 2012; 13: 234-257.
45. Seimon RV, Hostland N, Silveira SL, Gibson AA, Sainsbury A. Effects of energy restriction on activity of the hypothalamopituitary-adrenal axis in obese humans and rodents: implications for diet-induced changes in body composition. Horm Mol Biol Clin Investig 2013; 15: 71-80.
46. Mustajoki P, Pekkarinen T. Very low energy diets in the treatment of obesity. Obes Rev 2001; 2: 61-72.
47. O'Brien PE, Dixon JB, Laurie C et al. Treatment of mild to moderate obesity with laparoscopic adjustable gastric banding or an intensive medical program. Ann Intern Med 2006; 144: 625- 633.
48. Sjöström L, Narbro K, Sjöström D et al. Effects of bariatric surgery on mortality in Swedish obese subjects. New Engl J Med 2007; 357: 741-752.
49. Mathus-Vliegen EM. Intragastric balloon treatment for obesity: what does it really offer? Dig Dis 2008; 26: 40-44.
50. Patel JA, Colella JJ, Esaka E, Patel NA, Thomas RL. Improvement in infertility and pregnancy outcomes after weight loss surgery. Med Clin North Am 2007; 91: 515-528.
51. Merhi ZO. Weight loss by bariatric surgery and subsequent fertility. Fertil Steril 2007; 87: 430-432.
52. Skull AJ, Slater GH, Duncombe JE, Fielding GA. Laparoscopic adjustable banding in pregnancy: safety, patient tolerance and effect on obesity-related pregnancy outcomes. Obes Surg 2004; 14: 230-235.
53. Bar-Zohar D, Azem F, Klausner J, Abu-Abeid S. Pregnancy after laparoscopic adjustable gastric banding: perinatal outcome is favorable also for women with relatively high gestational weight gain. Surg Endosc 2006; 20: 1580-1583.
54. Dixon JB, Dixon ME, O'Brien PE. Birth outcomes in obese women after laparoscopic adjustable gastric banding. Obstet Gynecol 2005; 106: 965-972.
55. Sheiner E, Levy A, Silverberg D et al. Pregnancy after bariatric surgery is not associated with adverse perinatal outcome. Am J Obstet Gynecol 2004; 190: 1335-1340.
56. Catalano PM. Management of obesity in pregnancy. Obstet Gynecol 2007; 109: 419-433.
57. Khan R, Bashir D, Chappatte O. Pregnancy outcome following bariatic surgery. Obstet Gynecol 2013; 15: 37- 43.
58. American College of Obstetricians and Gynecologist. Female age-related fertility decline. Committee opinion no. 589. Obstet Gynecol 2014; 123: 719-721.
59. Sneed M, Uhler ML, Grotjan HE, Rapisarda JJ, Lederer KJ, Beltsos AN. Body mass index: impact on IVF success appears age-related. Hum Reprod 2008; 23: 1835-1839.
60. Gillett W, Putt T, Farquhar C. Prioritising for fertility treatments - the effect of excluding women with a high body mass index. BJOG 2006; 113: 1218-1221.
61. Maheshwari A. Overweight and obesity in infertility: cost and consequences. Hum Reprod Update 2010; 16: 229-230.
62. Maheshwari A, Scotland G, Bell J, McTavish A, Hamilton M, Bhattacharya S. The direct health services costs of providing assisted reproduction services in overweight or obese women: a retrospective cross-sectional analysis. Hum Reprod 2009; 24: 633- 639.
63. Pandey S, Maheshwari A, Bhattacharya S. Should access to fertility treatment be determined by female body mass index? Hum Reprod 2010; 25: 815-820.
64. Chavarro JE, Ehrlich S, Colaci DS et al. Body mass index and short-term weight change in relation to treatment outcomes in women undergoing assisted reproduction. Fertil Steril 2012; 98: 109-116.
65. National Institute for Health and Clinical Excellence. Fertility: Assessment and Treatment for People with Fertility Problems. NICE Clinical Guideline 156. National Institute for Health and Clinical Excellence: Manchester, 2013.
66. American College of Obstetricians and Gynecologists. Obesity in pregnancy. Committee opinion no. 549. Obstet Gynecol 2013; 121: 213-217.
67. Mutsaerts MA, Groen H, ter Bogt NC et al. The LIFESTYLE study: costs and effects of a structured lifestyle program in overweight and obese subfertile women to reduce the need for fertility treatment and improve reproductive outcome. A randomised controlled trial. BMC Womens Health 2010; 10: 22.