Urinary and sexual dysfunction in women after resection with and without preoperative radiotherapy for rectal cancer: A population-based cross-sectional study

Colorectal Disease

Volumn 17, Issue 1, 2015, Pages 26-37

  Bregendahl, S ^a   Emmertsen, K J ^a   Lindegaard, J C ^a   Laurberg, S ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Abdominoperineal excision; Low anterior resection; Preoperative radiotherapy; Rectal cancer; Sexual dysfunction; Urinary dysfunction

Indexed keywords

FLUOROURACIL;

ADULT; AGED; ARTICLE; ASSESSMENT OF HUMANS; BLADDER DISEASE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURGERY; CROSS-SECTIONAL STUDY; DENMARK; DYSPAREUNIA; FEMALE; HUMAN; ICIQ (INCONTINENCE); INTERNATIONAL CONSULTATION ON INCONTINENCE MODULAR QUESTIONNAIRE FEMALE LOWER URINARY TRACT SYMPTOMS; INTERRUPTED STREAM; MAJOR CLINICAL STUDY; MICTURITION DISORDER; NOCTURIA; NOCTURNAL ENURESIS; POSTOPERATIVE COMPLICATION; PREOPERATIVE RADIOTHERAPY; PRIORITY JOURNAL; RECTUM ABDOMINOPERINEAL RESECTION; RECTUM ANTERIOR RESECTION; RECTUM CANCER; REDUCED VAGINAL DIMENSION; SEXUAL BEHAVIOR; SEXUAL DISSATISFACTION; SEXUAL DYSFUNCTION; SEXUAL FUNCTION VAGINAL CHANGES QUESTIONNAIRE; STRESS INCONTINENCE; URINARY DYSFUNCTION; URINARY FREQUENCY; URINARY HESITANCY; URINARY URGENCY; VAGINAL DRYNESS; FECAL INCONTINENCE; MIDDLE AGED; PREOPERATIVE CARE; QUESTIONNAIRE; RADIATION RESPONSE; RECTAL NEOPLASMS; SEXUAL DYSFUNCTION, PHYSIOLOGICAL; URINARY INCONTINENCE; URINATION DISORDERS; VAGINA; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; CROSS-SECTIONAL STUDIES; DENMARK; DYSPAREUNIA; FECAL INCONTINENCE; FEMALE; HUMANS; MIDDLE AGED; POSTOPERATIVE COMPLICATIONS; PREOPERATIVE CARE; QUESTIONNAIRES; RECTAL NEOPLASMS; SEXUAL BEHAVIOR; SEXUAL DYSFUNCTION, PHYSIOLOGICAL; URINARY INCONTINENCE; URINATION DISORDERS; VAGINA;

EID: 84925843458     PISSN: 14628910     EISSN: 14631318     Source Type: Journal    
DOI: 10.1111/codi.12758     Document Type: Article

References (35)

1. Emmertsen KJ, Laurberg S. Impact of bowel dysfunction on quality of life after sphincter-preserving resection for rectal cancer. Br J Surg 2013; 100: 1377-87.
2. Hassan I, Cima RR. Quality of life after rectal resection and multimodality therapy. J Surg Oncol 2007; 96: 684-92.
3. Bryant CL, Lunniss PJ, Knowles CH et al. Anterior resection syndrome. Lancet Oncol 2012; 13: e403-8.
4. Lange MM, van de Velde CJ. Urinary and sexual dysfunction after rectal cancer treatment. Nat Rev Urol 2011; 8: 51-7.
5. Ho VP, Lee Y, Stein SL et al. Sexual function after treatment for rectal cancer: a review. Dis Colon Rectum 2011; 54: 113-25.
6. Emmertsen KJ, Laurberg S. Low anterior resection syndrome score: development and validation of a symptom-based scoring system for bowel dysfunction after low anterior resection for rectal cancer. Ann Surg 2012; 255: 922-8.
7. Bregendahl S, Emmertsen KJ, Lous J et al. Bowel dysfunction after low anterior resection with and without neoadjuvant therapy for rectal cancer: a population-based cross-sectional study. Colorectal Dis 2013; 15: 1130-9.
8. Brookes ST, Donovan JL, Wright M et al. A scored form of the Bristol Female Lower Urinary Tract Symptoms questionnaire: data from a randomized controlled trial of surgery for women with stress incontinence. Am J Obstet Gynecol 2004; 191: 73-82.
9. Jensen PT, Klee MC, Thranov I et al. Validation of a questionnaire for self-assessment of sexual function and vaginal changes after gynaecological cancer. Psychooncology 2004; 13: 577-92.
10. Marijnen CA, van de Velde CJ, Putter H et al. Impact of short-term preoperative radiotherapy on health-related quality of life and sexual functioning in primary rectal cancer: report of a multicenter randomized trial. J Clin Oncol 2005; 23: 1847-58.
11. Hendren SK, O'Connor BI, Liu M et al. Prevalence of male and female sexual dysfunction is high following surgery for rectal cancer. Ann Surg 2005; 242: 212-23.
12. Tekkis PP, Cornish JA, Remzi FH et al. Measuring sexual and urinary outcomes in women after rectal cancer excision. Dis Colon Rectum 2009; 52: 46-54.
13. Lange MM, Marijnen CA, Maas CP et al. Risk factors for sexual dysfunction after rectal cancer treatment. Eur J Cancer 2009; 45: 1578-88.
14. Lachowsky M, Nappi RE. The effects of oestrogen on urogenital health. Maturitas 2009; 63: 149-51.
15. Lange MM, Maas CP, Marijnen CA et al. Urinary dysfunction after rectal cancer treatment is mainly caused by surgery. Br J Surg 2008; 95: 1020-8.
16. Bruheim K, Tveit KM, Skovlund E et al. Sexual function in females after radiotherapy for rectal cancer. Acta Oncol 2010; 49: 826-32.
17. Pollack J, Holm T, Cedermark B et al. Late adverse effects of short-course preoperative radiotherapy in rectal cancer. Br J Surg 2006; 93: 1519-25.
18. van DP, Slors JF, Taat CW et al. Prospective evaluation of anorectal function after total mesorectal excision for rectal carcinoma with or without preoperative radiotherapy. Am J Gastroenterol 2002; 97: 2282-9.
19. Varpe P, Huhtinen H, Rantala A et al. Quality of life after surgery for rectal cancer with special reference to pelvic floor dysfunction. Colorectal Dis 2011; 13: 399-405.
20. Garlipp B, Ptok H, Schmidt U et al. Neoadjuvant chemoradiotherapy for rectal carcinoma: effects on anastomotic leak rate and postoperative bladder dysfunction after non-emergency sphincter-preserving anterior rectal resection. Results of the Quality Assurance in Rectal Cancer Surgery multicenter observational trial. Langenbecks Arch Surg 2010; 395: 1031-8.
21. Chatwin NA, Ribordy M, Givel JC. Clinical outcomes and quality of life after low anterior resection for rectal cancer. Eur J Surg 2002; 168: 297-301.
22. Prabhudesai AG, Cornes P, Glees JP et al. Long-term morbidity following short-course, pre-operative radiotherapy and total mesorectal excision for rectal cancer. Surgeon 2005; 3: 347-51.
23. Guckenberger M, Saur G, Wehner D et al. Long-term quality-of-life after neoadjuvant short-course radiotherapy and long-course radiochemotherapy for locally advanced rectal cancer. Radiother Oncol 2013; 108: 326-30.
24. Havenga K, Maas CP, DeRuiter MC et al. Avoiding long-term disturbance to bladder and sexual function in pelvic surgery, particularly with rectal cancer. Semin Surg Oncol 2000; 18: 235-43.
25. Lange MM, den DM, Bossema ER et al. Risk factors for faecal incontinence after rectal cancer treatment. Br J Surg 2007; 94: 1278-84.
26. Daniels IR, Woodward S, Taylor FG et al. Female urogenital dysfunction following total mesorectal excision for rectal cancer. World J Surg Oncol 2006; 4: 6.
27. Platell CF, Thompson PJ, Makin GB. Sexual health in women following pelvic surgery for rectal cancer. Br J Surg 2004; 91: 465-8.
28. Coyne KS, Cash B, Kopp Z et al. The prevalence of chronic constipation and faecal incontinence among men and women with symptoms of overactive bladder. BJU Int 2011; 107: 254-61.
29. Manning J, Eyers AA, Korda A et al. Is there an association between fecal incontinence and lower urinary dysfunction? Dis Colon Rectum 2001; 44: 790-8.
30. Soligo M, Salvatore S, Milani R et al. Double incontinence in urogynecologic practice: a new insight. Am J Obstet Gynecol 2003; 189: 438-43.
31. Bharucha AE. Pelvic floor: anatomy and function. Neurogastroenterol Motil 2006; 18: 507-19.
32. Swash M, Snooks SJ, Henry MM. Unifying concept of pelvic floor disorders and incontinence. J R Soc Med 1985; 78: 906-11.
33. Emmertsen KJ, Bregendahl S, Fassov J et al. A hyperactive postprandial response in the neorectum - The clue to Low Anterior Resection Syndrome after TME surgery? Colorectal Dis 2013; 15: e599-606.
34. Bregendahl S, Emmertsen KJ, Fassov J et al. Neorectal hyposensitivity after neoadjuvant therapy for rectal cancer. Radiother Oncol 2013; 108: 331-6.
35. Peduzzi P, Concato J, Kemper E et al. A simulation study of the number of events per variable in logistic regression analysis. J Clin Epidemiol 1996; 49: 1373-9.