-
1
-
-
84890948464
-
Biomarker-driven therapeutic management of Alzheimer's disease: Establishing the foundations
-
Cummings J, Zhong K (2014) Biomarker-driven therapeutic management of Alzheimer's disease: Establishing the foundations. Clin Pharmacol Ther 95, 67-77.
-
(2014)
Clin Pharmacol Ther
, vol.95
, pp. 67-77
-
-
Cummings, J.1
Zhong, K.2
-
2
-
-
84859052757
-
Accuracy of the clinical diagnosis of Alzheimer disease at National Institute on Aging Alzheimer Disease Centers, 2005-2010
-
Beach TG, Monsell SE, Phillips LE, Kukull W (2012) Accuracy of the clinical diagnosis of Alzheimer disease at National Institute on Aging Alzheimer Disease Centers, 2005-2010. J Neuropathol Exp Neurol 71, 266-273.
-
(2012)
J Neuropathol Exp Neurol
, vol.71
, pp. 266-273
-
-
Beach, T.G.1
Monsell, S.E.2
Phillips, L.E.3
Kukull, W.4
-
3
-
-
79956142378
-
The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
-
McKhann GM, Knopman DS, Chertkow H, Hyman BT, Jack CR Jr, Kawas CH, Klunk WE, Koroshetz WJ, Manly JJ, Mayeux R, Mohs RC, Morris JC, Rossor MN, Scheltens P, Carrillo MC, Thies B, Weintraub S, Phelps CH (2011) The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 7, 263-269.
-
(2011)
Alzheimers Dement
, vol.7
, pp. 263-269
-
-
McKhann, G.M.1
Knopman, D.S.2
Chertkow, H.3
Hyman, B.T.4
Jack, C.R.5
Kawas, C.H.6
Klunk, W.E.7
Koroshetz, W.J.8
Manly, J.J.9
Mayeux, R.10
Mohs, R.C.11
Morris, J.C.12
Rossor, M.N.13
Scheltens, P.14
Carrillo, M.C.15
Thies, B.16
Weintraub, S.17
Phelps, C.H.18
-
4
-
-
84900988440
-
Advancing research diagnostic criteria for Alzheimer's disease: The IWG-2 criteria
-
Dubois B, Feldman HH, Jacova C, Hampel H, Molinuevo JL, Blennow K, DeKosky ST, Gauthier S, Selkoe D, Bateman R, Cappa S, Crutch S, Engelborghs S, Frisoni GB, Fox NC, Galasko D, Habert MO, Jicha GA, Nordberg A, Pasquier F, Rabinovici G, Robert P, Rowe C, Salloway S, Sarazin M, Epelbaum S, de Souza LC, Vellas B, Visser PJ, Schneider L, Stern Y, Scheltens P, Cummings JL (2014) Advancing research diagnostic criteria for Alzheimer's disease: The IWG-2 criteria. Lancet Neurol 13, 614-629.
-
(2014)
Lancet Neurol
, vol.13
, pp. 614-629
-
-
Dubois, B.1
Feldman, H.H.2
Jacova, C.3
Hampel, H.4
Molinuevo, J.L.5
Blennow, K.6
DeKosky, S.T.7
Gauthier, S.8
Selkoe, D.9
Bateman, R.10
Cappa, S.11
Crutch, S.12
Engelborghs, S.13
Frisoni, G.B.14
Fox, N.C.15
Galasko, D.16
Habert, M.O.17
Jicha, G.A.18
Nordberg, A.19
Pasquier, F.20
Rabinovici, G.21
Robert, P.22
Rowe, C.23
Salloway, S.24
Sarazin, M.25
Epelbaum, S.26
De Souza, L.C.27
Vellas, B.28
Visser, P.J.29
Schneider, L.30
Stern, Y.31
Scheltens, P.32
Cummings, J.L.33
more..
-
5
-
-
0141738373
-
CSF markers for incipient Alzheimer's disease
-
Blennow K, Hampel H (2003) CSF markers for incipient Alzheimer's disease. Lancet Neurol 2, 605-613.
-
(2003)
Lancet Neurol
, vol.2
, pp. 605-613
-
-
Blennow, K.1
Hampel, H.2
-
6
-
-
79956098248
-
Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
-
Sperling RA, Aisen PS, Beckett LA, Bennett DA, Craft S, Fagan AM, Iwatsubo T, Jack CR Jr, Kaye J, Montine TJ, Park DC, Reiman EM, Rowe CC, Siemers E, Stern Y, Yaffe K, Carrillo MC, Thies B, Morrison-Bogorad M, Wagster MV, Phelps CH (2011) Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 7, 280-292.
-
(2011)
Alzheimers Dement
, vol.7
, pp. 280-292
-
-
Sperling, R.A.1
Aisen, P.S.2
Beckett, L.A.3
Bennett, D.A.4
Craft, S.5
Fagan, A.M.6
Iwatsubo, T.7
Jack, C.R.8
Kaye, J.9
Montine, T.J.10
Park, D.C.11
Reiman, E.M.12
Rowe, C.C.13
Siemers, E.14
Stern, Y.15
Yaffe, K.16
Carrillo, M.C.17
Thies, B.18
Morrison-Bogorad, M.19
Wagster, M.V.20
Phelps, C.H.21
more..
-
7
-
-
80052775337
-
Comparison of analytical platforms for cerebrospinal fluid measures of beta-amyloid 1-42, total tau, and p-tau181 for identifying Alzheimer disease amyloid plaque pathology
-
Fagan AM, Shaw LM, Xiong C, Vanderstichele H, Mintun MA, Trojanowski JQ, Coart E, Morris JC, Holtzman DM (2011) Comparison of analytical platforms for cerebrospinal fluid measures of beta-amyloid 1-42, total tau, and p-tau181 for identifying Alzheimer disease amyloid plaque pathology. Arch Neurol 68, 1137-1144.
-
(2011)
Arch Neurol
, vol.68
, pp. 1137-1144
-
-
Fagan, A.M.1
Shaw, L.M.2
Xiong, C.3
Vanderstichele, H.4
Mintun, M.A.5
Trojanowski, J.Q.6
Coart, E.7
Morris, J.C.8
Holtzman, D.M.9
-
8
-
-
84872463342
-
Comparison of two analytical platforms for the clinical qualification of Alzheimer's disease biomarkers in pathologically-confirmed dementia
-
Le Bastard N, Coart E, Vanderstichele H, Vanmechelen E, Martin JJ, Engelborghs S (2013) Comparison of two analytical platforms for the clinical qualification of Alzheimer's disease biomarkers in pathologically-confirmed dementia. J Alzheimers Dis 33, 117-131.
-
(2013)
J Alzheimers Dis
, vol.33
, pp. 117-131
-
-
Le Bastard, N.1
Coart, E.2
Vanderstichele, H.3
Vanmechelen, E.4
Martin, J.J.5
Engelborghs, S.6
-
9
-
-
84902275846
-
Comparison of two analytical platforms for CSF biomarkers of Alzheimer's disease
-
Monge-Argiles JA, Munoz-Ruiz C, Sanchez-Paya J, Gasparini Berenguer R, Blanco Canto ME, Leiva-Santana C (2014) Comparison of two analytical platforms for CSF biomarkers of Alzheimer's disease. Biomed Res Int 2014, 765130.
-
(2014)
Biomed Res Int
, vol.2014
, pp. 765130
-
-
Monge-Argiles, J.A.1
Munoz-Ruiz, C.2
Sanchez-Paya, J.3
Gasparini Berenguer, R.4
Blanco Canto, M.E.5
Leiva-Santana, C.6
-
10
-
-
84925698083
-
-
McCush F, Chappell J, Raha N, Durham R, Sharma V, Tew Z, Lane D. Validation of Alzheimer biomarkers assays using various analytical techniques in CSF and plasma, http://www.iconplc.com/icon-files/docs/thought-leadership/public/Validation-of-Alzheimer-Biomarkers-Assays-Using-Various-Analytical-Techniques-in-CSF-and-Plasma.pdf
-
Validation of Alzheimer Biomarkers Assays Using Various Analytical Techniques in CSF and Plasma
-
-
McCush, F.1
Chappell, J.2
Raha, N.3
Durham, R.4
Sharma, V.5
Tew, Z.6
Lane, D.7
-
11
-
-
84862774264
-
Development and advanced validation of an optimized method for the quantitation of Abeta42 in human cerebrospinal fluid
-
Cullen VC, Fredenburg RA, Evans C, Conliffe PR, Solomon ME (2012) Development and advanced validation of an optimized method for the quantitation of Abeta42 in human cerebrospinal fluid. AAPS J 14, 510-518.
-
(2012)
AAPS J
, vol.14
, pp. 510-518
-
-
Cullen, V.C.1
Fredenburg, R.A.2
Evans, C.3
Conliffe, P.R.4
Solomon, M.E.5
-
12
-
-
84878439275
-
Clinical utility and analytical challenges in measurement of cerebrospinal fluid amyloid-beta(1-42) and tau proteins as Alzheimer disease biomarkers
-
Kang JH, Korecka M, Toledo JB, Trojanowski JQ, Shaw LM (2013) Clinical utility and analytical challenges in measurement of cerebrospinal fluid amyloid-beta(1-42) and tau proteins as Alzheimer disease biomarkers. Clin Chem 59, 903-916.
-
(2013)
Clin Chem
, vol.59
, pp. 903-916
-
-
Kang, J.H.1
Korecka, M.2
Toledo, J.B.3
Trojanowski, J.Q.4
Shaw, L.M.5
-
13
-
-
84876909712
-
CSF biomarker variability in the Alzheimer's Association quality control program
-
Mattsson N, Andreasson U, Persson S, Carrillo MC, Collins S, Chalbot S, Cutler N, Dufour-Rainfray D, Fagan AM, Heegaard NH, Robin Hsiung GY, Hyman B, Iqbal K, Lachno DR, Lleo A, Lewczuk P, Molinuevo JL, Parchi P, Regeniter A, Rissman R, Rosenmann H, Sancesario G, Schroder J, Shaw LM, Teunissen CE, Trojanowski JQ, Vanderstichele H, Vandijck M, Verbeek MM, Zetterberg H, Blennow K, Kaser SA, Alzheimer's Association QCPWG (2013) CSF biomarker variability in the Alzheimer's Association quality control program. Alzheimers Dement 9, 251-261.
-
(2013)
Alzheimers Dement
, vol.9
, pp. 251-261
-
-
Alzheimer's Association QCPWG1
Mattsson, N.2
Andreasson, U.3
Persson, S.4
Carrillo, M.C.5
Collins, S.6
Chalbot, S.7
Cutler, N.8
Dufour-Rainfray, D.9
Fagan, A.M.10
Heegaard, N.H.11
Robin Hsiung, G.Y.12
Hyman, B.13
Iqbal, K.14
Lachno, D.R.15
Lleo, A.16
Lewczuk, P.17
Molinuevo, J.L.18
Parchi, P.19
Regeniter, A.20
Rissman, R.21
Rosenmann, H.22
Sancesario, G.23
Schroder, J.24
Shaw, L.M.25
Teunissen, C.E.26
Trojanowski, J.Q.27
Vanderstichele, H.28
Vandijck, M.29
Verbeek, M.M.30
Zetterberg, H.31
Blennow, K.32
Kaser, S.A.33
more..
-
14
-
-
79960764322
-
The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers
-
Mattsson N, Andreasson U, Persson S, Arai H, Batish SD, Bernardini S, Bocchio-Chiavetto L, Blankenstein MA, Carrillo MC, Chalbot S, Coart E, Chiasserini D, Cutler N, Dahlfors G, Duller S, Fagan AM, Forlenza O, Frisoni GB, Galasko D, Galimberti D, Hampel H, Handberg A, Heneka MT, Herskovits AZ, Herukka SK, Holtzman DM, Humpel C, Hyman BT, Iqbal K, Jucker M, Kaeser SA, Kaiser E, Kapaki E, Kidd D, Klivenyi P, Knudsen CS, Kummer MP, Lui J, Llado A, Lewczuk P, Li QX, Martins R, Masters C, McAuliffe J, Mercken M, Moghekar A, Molinuevo JL, Montine TJ, Nowatzke W, O'Brien R, Otto M, Paraskevas GP, Parnetti L, Petersen RC, Prvulovic D, de Reus HP, Rissman RA, Scarpini E, Stefani A, Soininen H, Schroder J, Shaw LM, Skinningsrud A, Skrogstad B, Spreer A, Talib L, Teunissen C, Trojanowski JQ, Tumani H, Umek RM, Van Broeck B, Vanderstichele H, Vecsei L, Verbeek MM, Windisch M, Zhang J, Zetterberg H, Blennow K (2011) The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers. Alzheimers Dement 7, 386-395 e386.
-
(2011)
Alzheimers Dement
, vol.7
-
-
Mattsson, N.1
Andreasson, U.2
Persson, S.3
Arai, H.4
Batish, S.D.5
Bernardini, S.6
Bocchio-Chiavetto, L.7
Blankenstein, M.A.8
Carrillo, M.C.9
Chalbot, S.10
Coart, E.11
Chiasserini, D.12
Cutler, N.13
Dahlfors, G.14
Duller, S.15
Fagan, A.M.16
Forlenza, O.17
Frisoni, G.B.18
Galasko, D.19
Galimberti, D.20
Hampel, H.21
Handberg, A.22
Heneka, M.T.23
Herskovits, A.Z.24
Herukka, S.K.25
Holtzman, D.M.26
Humpel, C.27
Hyman, B.T.28
Iqbal, K.29
Jucker, M.30
Kaeser, S.A.31
Kaiser, E.32
Kapaki, E.33
Kidd, D.34
Klivenyi, P.35
Knudsen, C.S.36
Kummer, M.P.37
Lui, J.38
Llado, A.39
Lewczuk, P.40
Li, Q.X.41
Martins, R.42
Masters, C.43
McAuliffe, J.44
Mercken, M.45
Moghekar, A.46
Molinuevo, J.L.47
Montine, T.J.48
Nowatzke, W.49
O'Brien, R.50
Otto, M.51
Paraskevas, G.P.52
Parnetti, L.53
Petersen, R.C.54
Prvulovic, D.55
De Reus, H.P.56
Rissman, R.A.57
Scarpini, E.58
Stefani, A.59
Soininen, H.60
Schroder, J.61
Shaw, L.M.62
Skinningsrud, A.63
Skrogstad, B.64
Spreer, A.65
Talib, L.66
Teunissen, C.67
Trojanowski, J.Q.68
Tumani, H.69
Umek, R.M.70
Van Broeck, B.71
Vanderstichele, H.72
Vecsei, L.73
Verbeek, M.M.74
Windisch, M.75
Zhang, J.76
Zetterberg, H.77
Blennow, K.78
more..
-
15
-
-
73449137232
-
Use of cerebrospinal fluid biomarkers in diagnosis of dementia across Europe
-
Hort J, Bartos A, Pirttila T, Scheltens P (2010) Use of cerebrospinal fluid biomarkers in diagnosis of dementia across Europe. Eur J Neurol 17, 90-96.
-
(2010)
Eur J Neurol
, vol.17
, pp. 90-96
-
-
Hort, J.1
Bartos, A.2
Pirttila, T.3
Scheltens, P.4
-
16
-
-
84927178751
-
The clinical use of cerebrospinal fluid biomarker testing for Alzheimer's disease diagnosis: A consensus paper from the Alzheimer's Biomarkers Standardization Initiative
-
Molinuevo JL, Blennow K, Dubois B, Engelborghs S, Lewczuk P, Perret-Liaudet A, Teunissen CE, Parnetti L (2014) The clinical use of cerebrospinal fluid biomarker testing for Alzheimer's disease diagnosis: A consensus paper from the Alzheimer's Biomarkers Standardization Initiative. Alzheimers Dement 10, 808-817.
-
(2014)
Alzheimers Dement
, vol.10
, pp. 808-817
-
-
Molinuevo, J.L.1
Blennow, K.2
Dubois, B.3
Engelborghs, S.4
Lewczuk, P.5
Perret-Liaudet, A.6
Teunissen, C.E.7
Parnetti, L.8
-
17
-
-
84907978955
-
Accuracy of brain amyloid detection in clinical practice using cerebrospinal fluid betaamyloid 42:Across-validation study against amyloid positron emission tomography
-
Palmqvist S, Zetterberg H, Blennow K, Vestberg S, Andreasson U, Brooks DJ, Owenius R, Hagerstrom D, Wollmer P, Minthon L, Hansson O (2014) Accuracy of brain amyloid detection in clinical practice using cerebrospinal fluid betaamyloid 42:Across-validation study against amyloid positron emission tomography. JAMA Neurol 71, 1282-1289.
-
(2014)
JAMA Neurol
, vol.71
, pp. 1282-1289
-
-
Palmqvist, S.1
Zetterberg, H.2
Blennow, K.3
Vestberg, S.4
Andreasson, U.5
Brooks, D.J.6
Owenius, R.7
Hagerstrom, D.8
Wollmer, P.9
Minthon, L.10
Hansson, O.11
-
18
-
-
80053492963
-
Validation of ELISA methods for quantification of total tau and phosporylated-tau181 in human cerebrospinal fluid with measurement in specimens from two Alzheimer's disease studies
-
Lachno DR, Romeo MJ, Siemers ER, Vanderstichele H, Coart E, Konrad RJ, Zajac JJ, Talbot JA, Jensen HF, Sethuraman G, Demattos RB, May PC, Dean RA (2011) Validation of ELISA methods for quantification of total tau and phosporylated-tau181 in human cerebrospinal fluid with measurement in specimens from two Alzheimer's disease studies. J Alzheimers Dis 26, 531-541.
-
(2011)
J Alzheimers Dis
, vol.26
, pp. 531-541
-
-
Lachno, D.R.1
Romeo, M.J.2
Siemers, E.R.3
Vanderstichele, H.4
Coart, E.5
Konrad, R.J.6
Zajac, J.J.7
Talbot, J.A.8
Jensen, H.F.9
Sethuraman, G.10
Demattos, R.B.11
May, P.C.12
Dean, R.A.13
-
19
-
-
84862128944
-
Simultaneous analysis of cerebrospinal fluid biomarkers using microsphere-based xMAP multiplex technology for early detection of Alzheimer's disease
-
Kang JH, Vanderstichele H, Trojanowski JQ, Shaw LM (2012) Simultaneous analysis of cerebrospinal fluid biomarkers using microsphere-based xMAP multiplex technology for early detection of Alzheimer's disease. Methods 56, 484-493.
-
(2012)
Methods
, vol.56
, pp. 484-493
-
-
Kang, J.H.1
Vanderstichele, H.2
Trojanowski, J.Q.3
Shaw, L.M.4
-
20
-
-
65249159879
-
Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects
-
Shaw LM, Vanderstichele H, Knapik-Czajka M, Clark CM, Aisen PS, Petersen RC, Blennow K, Soares H, Simon A, Lewczuk P, Dean R, Siemers E, Potter W, Lee VM, Trojanowski JQ, Alzheimer's Disease Neuroimaging I (2009) Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects. Ann Neurol 65, 403-413.
-
(2009)
Ann Neurol
, vol.65
, pp. 403-413
-
-
Shaw, L.M.1
Vanderstichele, H.2
Knapik-Czajka, M.3
Clark, C.M.4
Aisen, P.S.5
Petersen, R.C.6
Blennow, K.7
Soares, H.8
Simon, A.9
Lewczuk, P.10
Dean, R.11
Siemers, E.12
Potter, W.13
Lee, V.M.14
Trojanowski, J.Q.15
-
21
-
-
33745828142
-
Age and apolipoprotein E∗4 allele effects on cerebrospinal fluid beta-amyloid 42 in adults with normal cognition
-
Peskind ER, Li G, Shofer J, Quinn JF, Kaye JA, Clark CM, Farlow MR, DeCarli C, Raskind MA, Schellenberg GD, Lee VM, Galasko DR (2006) Age and apolipoprotein E∗4 allele effects on cerebrospinal fluid beta-amyloid 42 in adults with normal cognition. Arch Neurol 63, 936-939.
-
(2006)
Arch Neurol
, vol.63
, pp. 936-939
-
-
Peskind, E.R.1
Li, G.2
Shofer, J.3
Quinn, J.F.4
Kaye, J.A.5
Clark, C.M.6
Farlow, M.R.7
DeCarli, C.8
Raskind, M.A.9
Schellenberg, G.D.10
Lee, V.M.11
Galasko, D.R.12
-
22
-
-
0021271971
-
Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
-
McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34, 939-944.
-
(1984)
Neurology
, vol.34
, pp. 939-944
-
-
McKhann, G.1
Drachman, D.2
Folstein, M.3
Katzman, R.4
Price, D.5
Stadlan, E.M.6
-
23
-
-
84897840006
-
Cerebrospinal fluid alpha-synuclein predicts cognitive decline in Parkinson disease progression in the DATATOP cohort
-
Stewart T, Liu C, Ginghina C, Cain KC, Auinger P, Cholerton B, Shi M, Zhang J, Parkinson Study Group DATATOP Investigators (2014) Cerebrospinal fluid alpha-synuclein predicts cognitive decline in Parkinson disease progression in the DATATOP cohort. Am J Pathol 184, 966-975.
-
(2014)
Am J Pathol
, vol.184
, pp. 966-975
-
-
Parkinson Study Group DATATOP Investigators1
Stewart, T.2
Liu, C.3
Ginghina, C.4
Cain, K.C.5
Auinger, P.6
Cholerton, B.7
Shi, M.8
Zhang, J.9
-
24
-
-
84888202286
-
CSF alpha-synuclein improves diagnostic and prognostic performance of CSF tau and Abeta in Alzheimer's disease
-
Toledo JB, Korff A, Shaw LM, Trojanowski JQ, Zhang J (2013) CSF alpha-synuclein improves diagnostic and prognostic performance of CSF tau and Abeta in Alzheimer's disease. Acta Neuropathol 126, 683-697.
-
(2013)
Acta Neuropathol
, vol.126
, pp. 683-697
-
-
Toledo, J.B.1
Korff, A.2
Shaw, L.M.3
Trojanowski, J.Q.4
Zhang, J.5
-
25
-
-
79953283868
-
Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression
-
Shi M, Bradner J, Hancock AM, Chung KA, Quinn JF, Peskind ER, Galasko D, Jankovic J, Zabetian CP, Kim HM, Leverenz JB, Montine TJ, Ginghina C, Kang UJ, Cain KC, Wang Y, Aasly J, Goldstein D, Zhang J (2011) Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression. Ann Neurol 69, 570-580.
-
(2011)
Ann Neurol
, vol.69
, pp. 570-580
-
-
Shi, M.1
Bradner, J.2
Hancock, A.M.3
Chung, K.A.4
Quinn, J.F.5
Peskind, E.R.6
Galasko, D.7
Jankovic, J.8
Zabetian, C.P.9
Kim, H.M.10
Leverenz, J.B.11
Montine, T.J.12
Ginghina, C.13
Kang, U.J.14
Cain, K.C.15
Wang, Y.16
Aasly, J.17
Goldstein, D.18
Zhang, J.19
-
26
-
-
77950223687
-
DJ-1 and alpha-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease
-
Hong Z, Shi M, Chung KA, Quinn JF, Peskind ER, Galasko D, Jankovic J, Zabetian CP, Leverenz JB, Baird G, Montine TJ, Hancock AM, Hwang H, Pan C, Bradner J, Kang UJ, Jensen PH, Zhang J (2010) DJ-1 and alpha-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease. Brain 133, 713-726.
-
(2010)
Brain
, vol.133
, pp. 713-726
-
-
Hong, Z.1
Shi, M.2
Chung, K.A.3
Quinn, J.F.4
Peskind, E.R.5
Galasko, D.6
Jankovic, J.7
Zabetian, C.P.8
Leverenz, J.B.9
Baird, G.10
Montine, T.J.11
Hancock, A.M.12
Hwang, H.13
Pan, C.14
Bradner, J.15
Kang, U.J.16
Jensen, P.H.17
Zhang, J.18
-
27
-
-
84863164994
-
Phosphorylated alpha-synuclein in Parkinson's disease
-
Wang Y, Shi M, Chung KA, Zabetian CP, Leverenz JB, Berg D, Srulijes K, Trojanowski JQ, Lee VM, Siderowf AD, Hurtig H, Litvan I, Schiess MC, Peskind ER, Masuda M, Hasegawa M, Lin X, Pan C, Galasko D, Goldstein DS, Jensen PH, Yang H, Cain KC, Zhang J (2012) Phosphorylated alpha-synuclein in Parkinson's disease. Sci Transl Med 4, 121ra120.
-
(2012)
Sci Transl Med
, vol.4
, pp. 121ra120
-
-
Wang, Y.1
Shi, M.2
Chung, K.A.3
Zabetian, C.P.4
Leverenz, J.B.5
Berg, D.6
Srulijes, K.7
Trojanowski, J.Q.8
Lee, V.M.9
Siderowf, A.D.10
Hurtig, H.11
Litvan, I.12
Schiess, M.C.13
Peskind, E.R.14
Masuda, M.15
Hasegawa, M.16
Lin, X.17
Pan, C.18
Galasko, D.19
Goldstein, D.S.20
Jensen, P.H.21
Yang, H.22
Cain, K.C.23
Zhang, J.24
more..
-
28
-
-
32544451155
-
Fit-for-purpose method development and validation for successful biomarker measurement
-
Lee JW, Devanarayan V, Barrett YC, Weiner R, Allinson J, Fountain S, Keller S, Weinryb I, Green M, Duan L, Rogers JA, Millham R, O'Brien PJ, Sailstad J, Khan M, Ray C, Wagner JA(2006) Fit-for-purpose method development and validation for successful biomarker measurement. Pharm Res 23, 312-328.
-
(2006)
Pharm Res
, vol.23
, pp. 312-328
-
-
Lee, J.W.1
Devanarayan, V.2
Barrett, Y.C.3
Weiner, R.4
Allinson, J.5
Fountain, S.6
Keller, S.7
Weinryb, I.8
Green, M.9
Duan, L.10
Rogers, J.A.11
Millham, R.12
O'Brien, P.J.13
Sailstad, J.14
Khan, M.15
Ray, C.16
Wagner, J.A.17
-
29
-
-
10744230729
-
Recommendations for the bioanalytical method validation of ligand-binding assays to support pharmacokinetic assessments of macromolecules
-
DeSilva B, Smith W, Weiner R, Kelley M, Smolec J, Lee B, Khan M, Tacey R, Hill H, Celniker A (2003) Recommendations for the bioanalytical method validation of ligand-binding assays to support pharmacokinetic assessments of macromolecules. Pharm Res 20, 1885-1900.
-
(2003)
Pharm Res
, vol.20
, pp. 1885-1900
-
-
DeSilva, B.1
Smith, W.2
Weiner, R.3
Kelley, M.4
Smolec, J.5
Lee, B.6
Khan, M.7
Tacey, R.8
Hill, H.9
Celniker, A.10
-
30
-
-
79956075204
-
Validation of immunoassay for protein biomarkers: Bioanalytical study plan implementation to support pre-clinical and clinical studies
-
Valentin MA, Ma S, Zhao A, Legay F, Avrameas A (2011) Validation of immunoassay for protein biomarkers: Bioanalytical study plan implementation to support pre-clinical and clinical studies. J Pharm Biomed Anal 55, 869-877.
-
(2011)
J Pharm Biomed Anal
, vol.55
, pp. 869-877
-
-
Valentin, M.A.1
Ma, S.2
Zhao, A.3
Legay, F.4
Avrameas, A.5
-
31
-
-
0025257612
-
Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI
-
Hixson JE, Vernier DT (1990) Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J Lipid Res 31, 545-548.
-
(1990)
J Lipid Res
, vol.31
, pp. 545-548
-
-
Hixson, J.E.1
Vernier, D.T.2
-
32
-
-
0024119002
-
Genotyping and sequence analysis of apolipoprotein E isoforms
-
Emi M, Wu LL, Robertson MA, Myers RL, Hegele RA, Williams RR, White R, Lalouel JM (1988) Genotyping and sequence analysis of apolipoprotein E isoforms. Genomics 3, 373-379.
-
(1988)
Genomics
, vol.3
, pp. 373-379
-
-
Emi, M.1
Wu, L.L.2
Robertson, M.A.3
Myers, R.L.4
Hegele, R.A.5
Williams, R.R.6
White, R.7
Lalouel, J.M.8
-
33
-
-
47849090167
-
Multiple SNPs within and surrounding the apolipoprotein E gene influence cerebrospinal fluid apolipoprotein E protein levels
-
Bekris LM, Millard SP, Galloway NM, Vuletic S, Albers JJ, Li G, Galasko DR, DeCarli C, Farlow MR, Clark CM, Quinn JF, Kaye JA, Schellenberg GD, Tsuang D, Peskind ER, Yu CE (2008) Multiple SNPs within and surrounding the apolipoprotein E gene influence cerebrospinal fluid apolipoprotein E protein levels. J Alzheimers Dis 13, 255-266.
-
(2008)
J Alzheimers Dis
, vol.13
, pp. 255-266
-
-
Bekris, L.M.1
Millard, S.P.2
Galloway, N.M.3
Vuletic, S.4
Albers, J.J.5
Li, G.6
Galasko, D.R.7
DeCarli, C.8
Farlow, M.R.9
Clark, C.M.10
Quinn, J.F.11
Kaye, J.A.12
Schellenberg, G.D.13
Tsuang, D.14
Peskind, E.R.15
Yu, C.E.16
-
34
-
-
84890446929
-
Biomarkers in amyloid-beta immunotherapy trials in Alzheimer's disease
-
Blennow K, Hampel H, Zetterberg H (2014) Biomarkers in amyloid-beta immunotherapy trials in Alzheimer's disease. Neuropsychopharmacology 39, 189-201.
-
(2014)
Neuropsychopharmacology
, vol.39
, pp. 189-201
-
-
Blennow, K.1
Hampel, H.2
Zetterberg, H.3
-
35
-
-
84898044875
-
Meta-review of CSF core biomarkers in Alzheimer's disease: The state-of-the-art after the new revised diagnostic criteria
-
Ferreira D, Perestelo-Perez L, Westman E, Wahlund LO, Sarria A, Serrano-Aguilar P (2014) Meta-review of CSF core biomarkers in Alzheimer's disease: The state-of-the-art after the new revised diagnostic criteria. Front Aging Neurosci 6, 47.
-
(2014)
Front Aging Neurosci
, vol.6
, pp. 47
-
-
Ferreira, D.1
Perestelo-Perez, L.2
Westman, E.3
Wahlund, L.O.4
Sarria, A.5
Serrano-Aguilar, P.6
-
36
-
-
84856008210
-
Standardization of preanalytical aspects of cerebrospinal fluid biomarker testing for Alzheimer's disease diagnosis: A consensus paper from the Alzheimer's Biomarkers Standardization Initiative
-
Vanderstichele H, Bibl M, Engelborghs S, Le Bastard N, Lewczuk P, Molinuevo JL, Parnetti L, Perret-Liaudet A, Shaw LM, Teunissen C, Wouters D, Blennow K (2012) Standardization of preanalytical aspects of cerebrospinal fluid biomarker testing for Alzheimer's disease diagnosis: A consensus paper from the Alzheimer's Biomarkers Standardization Initiative. Alzheimers Dement 8, 65-73.
-
(2012)
Alzheimers Dement
, vol.8
, pp. 65-73
-
-
Vanderstichele, H.1
Bibl, M.2
Engelborghs, S.3
Le Bastard, N.4
Lewczuk, P.5
Molinuevo, J.L.6
Parnetti, L.7
Perret-Liaudet, A.8
Shaw, L.M.9
Teunissen, C.10
Wouters, D.11
Blennow, K.12
-
37
-
-
80051758766
-
Preanalytical sample handling and sample stability testing for the neurochemical dementia diagnostics
-
Zimmermann R, Lelental N, Ganslandt O, Maler JM, Kornhuber J, Lewczuk P (2011) Preanalytical sample handling and sample stability testing for the neurochemical dementia diagnostics. J Alzheimers Dis 25, 739-745.
-
(2011)
J Alzheimers Dis
, vol.25
, pp. 739-745
-
-
Zimmermann, R.1
Lelental, N.2
Ganslandt, O.3
Maler, J.M.4
Kornhuber, J.5
Lewczuk, P.6
-
38
-
-
84882456499
-
Intersite variability of CSF Alzheimer's disease biomarkers in clinical setting
-
Dumurgier J, Vercruysse O, Paquet C, Bombois S, Chaulet C, Laplanche JL, Peoc'h K, Schraen S, Pasquier F, Touchon J, Hugon J, Lehmann S, Gabelle A (2013) Intersite variability of CSF Alzheimer's disease biomarkers in clinical setting. Alzheimers Dement 9, 406-413.
-
(2013)
Alzheimers Dement
, vol.9
, pp. 406-413
-
-
Dumurgier, J.1
Vercruysse, O.2
Paquet, C.3
Bombois, S.4
Chaulet, C.5
Laplanche, J.L.6
Peoc'H, K.7
Schraen, S.8
Pasquier, F.9
Touchon, J.10
Hugon, J.11
Lehmann, S.12
Gabelle, A.13
-
39
-
-
84908234391
-
Impact of harmonization of collection tubes on Alzheimer's disease diagnosis
-
Lehmann S, Schraen S, Quadrio I, Paquet C, Bombois S, Delaby C, Dorey A, Dumurgier J, Hirtz C, Krolak-Salmon P, Laplanche JL, Moreaud O, Peoc'h K, Rouaud O, Sablonniere B, Thouvenot E, Touchon J, Vercruysse O, Hugon J, Gabelle A, Pasquier F, Perret-Liaudet A (2014) Impact of harmonization of collection tubes on Alzheimer's disease diagnosis. Alzheimers Dement 10, S390-S394 e392.
-
(2014)
Alzheimers Dement
, vol.10
-
-
Lehmann, S.1
Schraen, S.2
Quadrio, I.3
Paquet, C.4
Bombois, S.5
Delaby, C.6
Dorey, A.7
Dumurgier, J.8
Hirtz, C.9
Krolak-Salmon, P.10
Laplanche, J.L.11
Moreaud, O.12
Peoc'H, K.13
Rouaud, O.14
Sablonniere, B.15
Thouvenot, E.16
Touchon, J.17
Vercruysse, O.18
Hugon, J.19
Gabelle, A.20
Pasquier, F.21
Perret-Liaudet, A.22
more..
-
40
-
-
80055039147
-
Review and meta-analysis of biomarkers and diagnostic imaging in Alzheimer's disease
-
Bloudek LM, Spackman DE, Blankenburg M, Sullivan SD (2011) Review and meta-analysis of biomarkers and diagnostic imaging in Alzheimer's disease. J Alzheimers Dis 26, 627-645.
-
(2011)
J Alzheimers Dis
, vol.26
, pp. 627-645
-
-
Bloudek, L.M.1
Spackman, D.E.2
Blankenburg, M.3
Sullivan, S.D.4
-
41
-
-
84862753578
-
CSF biomarkers cutoffs: The importance of coincident neuropathological diseases
-
Toledo JB, Brettschneider J, Grossman M, Arnold SE, Hu WT, Xie SX, Lee VM, Shaw LM, Trojanowski JQ (2012) CSF biomarkers cutoffs: The importance of coincident neuropathological diseases. Acta Neuropathol 124, 23-35.
-
(2012)
Acta Neuropathol
, vol.124
, pp. 23-35
-
-
Toledo, J.B.1
Brettschneider, J.2
Grossman, M.3
Arnold, S.E.4
Hu, W.T.5
Xie, S.X.6
Lee, V.M.7
Shaw, L.M.8
Trojanowski, J.Q.9
-
42
-
-
77955944439
-
Lessons from multicenter studies on CSF biomarkers for Alzheimer's disease
-
Mattsson N, Zetterberg H, Blennow K (2010) Lessons from multicenter studies on CSF biomarkers for Alzheimer's disease. Int J Alzheimers Dis 2010, pii: 610613.
-
(2010)
Int J Alzheimers Dis
, vol.2010
, pp. 610613
-
-
Mattsson, N.1
Zetterberg, H.2
Blennow, K.3
-
43
-
-
58349084970
-
CSF biomarker profile and diagnostic value in vascular dementia
-
Paraskevas GP, Kapaki E, Papageorgiou SG, Kalfakis N, Andreadou E, Zalonis I, Vassilopoulos D (2009) CSF biomarker profile and diagnostic value in vascular dementia. Eur J Neurol 16, 205-211.
-
(2009)
Eur J Neurol
, vol.16
, pp. 205-211
-
-
Paraskevas, G.P.1
Kapaki, E.2
Papageorgiou, S.G.3
Kalfakis, N.4
Andreadou, E.5
Zalonis, I.6
Vassilopoulos, D.7
-
44
-
-
84889567749
-
Cerebrospinal fluid biomarkers in Alzheimer's disease, vascular dementia and ischemic stroke patients: A critical analysis
-
Kaerst L, Kuhlmann A, Wedekind D, Stoeck K, Lange P, Zerr I (2013) Cerebrospinal fluid biomarkers in Alzheimer's disease, vascular dementia and ischemic stroke patients: A critical analysis. J Neurol 260, 2722-2727.
-
(2013)
J Neurol
, vol.260
, pp. 2722-2727
-
-
Kaerst, L.1
Kuhlmann, A.2
Wedekind, D.3
Stoeck, K.4
Lange, P.5
Zerr, I.6
-
45
-
-
0033919992
-
Lewy bodies in Alzheimer's disease: A neuropathological review of 145 cases using alphasynuclein immunohistochemistry
-
Hamilton RL (2000) Lewy bodies in Alzheimer's disease: A neuropathological review of 145 cases using alphasynuclein immunohistochemistry. Brain Pathol 10, 378-384.
-
(2000)
Brain Pathol
, vol.10
, pp. 378-384
-
-
Hamilton, R.L.1
-
46
-
-
18344417178
-
Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes
-
Lippa CF, Fujiwara H, Mann DM, Giasson B, Baba M, Schmidt ML, Nee LE, O'Connell B, Pollen DA, St George-Hyslop P, Ghetti B, Nochlin D, Bird TD, Cairns NJ, Lee VM, Iwatsubo T, Trojanowski JQ (1998) Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes. Am J Pathol 153, 1365-1370.
-
(1998)
Am J Pathol
, vol.153
, pp. 1365-1370
-
-
Lippa, C.F.1
Fujiwara, H.2
Mann, D.M.3
Giasson, B.4
Baba, M.5
Schmidt, M.L.6
Nee, L.E.7
O'Connell, B.8
Pollen, D.A.9
St George-Hyslop, P.10
Ghetti, B.11
Nochlin, D.12
Bird, T.D.13
Cairns, N.J.14
Lee, V.M.15
Iwatsubo, T.16
Trojanowski, J.Q.17
-
47
-
-
79960353168
-
CSF alpha-synuclein, tau, and amyloid beta in Parkinson's disease
-
author's reply 681-683
-
Shi M, Zhang J (2011) CSF alpha-synuclein, tau, and amyloid beta in Parkinson's disease. Lancet Neurol 10, 681; author's reply 681-683.
-
(2011)
Lancet Neurol
, vol.10
, pp. 681
-
-
Shi, M.1
Zhang, J.2
-
48
-
-
79951720856
-
alpha-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: A cohort study
-
Mollenhauer B, Locascio JJ, Schulz-Schaeffer W, Sixel-Doring F, Trenkwalder C, Schlossmacher MG (2011) alpha-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: A cohort study. Lancet Neurol 10, 230-240.
-
(2011)
Lancet Neurol
, vol.10
, pp. 230-240
-
-
Mollenhauer, B.1
Locascio, J.J.2
Schulz-Schaeffer, W.3
Sixel-Doring, F.4
Trenkwalder, C.5
Schlossmacher, M.G.6
-
49
-
-
84885699313
-
Association of cerebrospinal fluid beta-amyloid 1-42, t-tau, p-tau181, and alpha-synuclein levels with clinical features of drug-naive patients with early Parkinson disease
-
Kang JH, Irwin DJ, Chen-Plotkin AS, Siderowf A, Caspell C, Coffey CS, Waligorska T, Taylor P, Pan S, Frasier M, Marek K, Kieburtz K, Jennings D, Simuni T, Tanner CM, Singleton A, Toga AW, Chowdhury S, Mollenhauer B, Trojanowski JQ, Shaw LM, the Parkinson's Progression Markers I (2013) Association of cerebrospinal fluid beta-amyloid 1-42, t-tau, p-tau181, and alpha-synuclein levels with clinical features of drug-naive patients with early Parkinson disease. JAMA Neurol 70, 1277-1287.
-
(2013)
JAMA Neurol
, vol.70
, pp. 1277-1287
-
-
Kang, J.H.1
Irwin, D.J.2
Chen-Plotkin, A.S.3
Siderowf, A.4
Caspell, C.5
Coffey, C.S.6
Waligorska, T.7
Taylor, P.8
Pan, S.9
Frasier, M.10
Marek, K.11
Kieburtz, K.12
Jennings, D.13
Simuni, T.14
Tanner, C.M.15
Singleton, A.16
Toga, A.W.17
Chowdhury, S.18
Mollenhauer, B.19
Trojanowski, J.Q.20
Shaw, L.M.21
more..
-
50
-
-
84856617005
-
Cerebrospinal fluid markers for differential dementia diagnosis in a large memory clinic cohort
-
Schoonenboom NS, Reesink FE, Verwey NA, Kester MI, Teunissen CE, van deVen PM, Pijnenburg YA, Blankenstein MA, Rozemuller AJ, Scheltens P, van der Flier WM (2012) Cerebrospinal fluid markers for differential dementia diagnosis in a large memory clinic cohort. Neurology 78, 47-54.
-
(2012)
Neurology
, vol.78
, pp. 47-54
-
-
Schoonenboom, N.S.1
Reesink, F.E.2
Verwey, N.A.3
Kester, M.I.4
Teunissen, C.E.5
Van DeVen, P.M.6
Pijnenburg, Y.A.7
Blankenstein, M.A.8
Rozemuller, A.J.9
Scheltens, P.10
Van Der Flier, W.M.11
-
51
-
-
77956935120
-
Added diagnostic value of CSF biomarkers in differential dementia diagnosis
-
Le Bastard N, Martin JJ, Vanmechelen E, Vanderstichele H, De Deyn PP, Engelborghs S (2010) Added diagnostic value of CSF biomarkers in differential dementia diagnosis. Neurobiol Aging 31, 1867-1876.
-
(2010)
Neurobiol Aging
, vol.31
, pp. 1867-1876
-
-
Le Bastard, N.1
Martin, J.J.2
Vanmechelen, E.3
Vanderstichele, H.4
De Deyn, P.P.5
Engelborghs, S.6
-
52
-
-
44949219321
-
Diagnostic performance of a CSF-biomarker panel in autopsy-confirmed dementia
-
Engelborghs S, De Vreese K, Van de Casteele T, Vanderstichele H, Van Everbroeck B, Cras P, Martin JJ, Vanmechelen E, De Deyn PP (2008) Diagnostic performance of a CSF-biomarker panel in autopsy-confirmed dementia. Neurobiol Aging 29, 1143-1159.
-
(2008)
Neurobiol Aging
, vol.29
, pp. 1143-1159
-
-
Engelborghs, S.1
De Vreese, K.2
Van De Casteele, T.3
Vanderstichele, H.4
Van Everbroeck, B.5
Cras, P.6
Martin, J.J.7
Vanmechelen, E.8
De Deyn, P.P.9
|