The effects of prenatal undernutrition and postnatal high-fat diet on hypothalamic Kiss1 mRNA and serum leptin levels

International Journal of Developmental Neuroscience

Volumn 42, Issue , 2015, Pages 76-79

  Iwasa, Takeshi ^a   Matsuzaki, Toshiya ^a   Munkhzaya, Munkhsaikhan ^a   Tungalagsuvd, Altankhuu ^a   Yamasaki, Mikio ^a   Kuwahara, Akira ^a   Yasui, Toshiyuki ^a   Irahara, Minoru ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

High fat diet; IUGR; Kiss1; Kisspeptin; Leptin

Indexed keywords

KISSPEPTIN; LEPTIN; LUTEINIZING HORMONE; MESSENGER RNA; G PROTEIN COUPLED RECEPTOR; GONADORELIN; KISS1 PROTEIN, RAT; KISS1R PROTEIN, RAT; NEUROPEPTIDE; NEUROPEPTIDE FF RECEPTOR; NEUROPEPTIDE RECEPTOR; RFAMIDE PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; FEMALE; FETAL MALNUTRITION; GENE; HYPOTHALAMUS; INTRAUTERINE GROWTH RETARDATION; KISS1 GENE; LIPID DIET; LUTEINIZING HORMONE BLOOD LEVEL; NONHUMAN; NUTRITIONAL STATUS; OVERNUTRITION; POSTNATAL CARE; PRENATAL DIAGNOSIS; PRENATAL PERIOD; PRIORITY JOURNAL; PUBERTY; RAT; REPRODUCTION; SEXUAL MATURATION; ANIMAL; BLOOD; GENETICS; MALE; MALNUTRITION; METABOLISM; NEWBORN; PATHOLOGY; PREGNANCY; PRENATAL EXPOSURE; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; ANIMALS, NEWBORN; BODY WEIGHT; FEMALE; GONADOTROPIN-RELEASING HORMONE; HYPOTHALAMUS; KISSPEPTINS; LEPTIN; MALE; MALNUTRITION; NEUROPEPTIDES; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NEUROPEPTIDE; RNA, MESSENGER;

EID: 84925796258     PISSN: 07365748     EISSN: 1873474X     Source Type: Journal    
DOI: 10.1016/j.ijdevneu.2015.03.001     Document Type: Article

References (15)

1. Barash I.H., Cheung C.C., Weigle D.S., Ren H., Kabigting E.B., Kuijper J.L., Clifton D.K., Steiner R.A. Leptin is a metabolic signal to the reproductive system. Endocrinology 1996, 137:3144-3147.
2. Delahaye F., Breton C., Risold P.Y., Enache M., Dutriez-Casteloot I., Laborie C., Lesage J., Vieau D. Maternal perinatal undernutrition drastically reduces postnatal leptin surge and affects the development of arcuate nucleus proopiomelanocortin neurons in neonatal male rat pups. Endocrinology 2008, 149:470-475.
3. Godfrey K.M., Barker D.J. Fetal nutrition and adult disease. Am. J. Clin. Nutr. 2000, 71:1344-1352.
4. Iwasa T., Matsuzaki T., Munkhzaya M., Tungalagsuvd A., Kawami T., Murakami M., Yamasaki M., Kato T., Kuwahara A., Yasui T., Irahara M. Pre-pubertal serum leptin levels and sensitivity to central leptin injection of prenatally undernourished female rats. Int. J. Dev. Neurosci. 2014, 35:52-54.
5. Iwasa T., Matsuzaki T., Tungalagsuvd A., Munkhzaya M., Kawami T., Niki H., Kato T., Kuwahara A., Uemura H., Yasui T., Irahara M. Hypothalamic Kiss1 and RFRP gene expressions are changed by a high dose of lipopolysaccharide in female rats. Horm. Behav. 2014, 66:309-316.
6. Iwasa T., Matsuzaki T., Munkhzaya M., Tungalagsuvd A., Kawami T., Murakami M., Yamasaki M., Kato T., Kuwahara A., Yasui T., Irahara M. Prenatal exposure to glucocorticoids affects body weight serum leptin levels, and hypothalamic neuroprptide-Y expression in pre-pubertal female rat offspring. Int. J. Dev. Neurosci. 2014, 36:1-4.
7. Iwasa T., Matsuzaki T., Munkhzaya M., Tungalagsuvd A., Kawami T., Murakami M., Yamasaki M., Kato T., Kuwahara A., Yasui T., Irahara M. Changes in the responsiveness of hypothalamic prokineticin 2 mRNA expression to food deprivation in developing female rats. Int. J. Dev. Neurosci. 2014, 34:76-78.
8. Iwasa T., Matsuzaki T., Tungalagsuvd A., Munkhzaya M., Kawami T., Yamasaki M., Murakami M., Kato T., Kuwahara A., Yasui T., Irahara M. Developmental changes in hypothalamic toll-like-receptor 4 mRNA expression and the effects of lipopolysaccharide on such changes in female rats. Int. J. Dev. Neurosci. 2015, 40:12-14.
9. Kaplowitz P.B. Link between body fat and the timing of puberty. Pediatrics 2008, 121:S208-S217.
10. Li X.F., Lin Y.S., Kinsey-Jones J.S., O'Byrne K.T. High-fat diet increases LH pulse frequency and kisspeptin-neurokinin B expression in puberty advanced female rats. Endocrinology 2012, 153:4422-4431.
11. Lie M.E., Overgaard A., Mikkelsen J.D. Effects of postnatal high-fat diet exposure on puberty onset estrous cycle regularity, and kisspeptin expression in female rats. Reprod. Biol. 2013, 13:298-308.
12. Poiling M.C., Shieh M.P., Munganuru N., Luo E., Kauffman A.S. Examination of the influence of leptin and acute metabolic challenge on RFRP-3 neurons of mice in development and adulthood. Neuroendocrinology 2014, in press.
13. Quennell J.H., Howell C.S., Roa H.J., Augustine R.A., Grattan D.R., Anderson G.M. Leptin deficiency and diet-induced obesity reduce hypothalamic kisspeptin expression in mice. Endocrinology 2011, 152:1541--1550.
14. True C., Kirigiti M.A., Kievit K., Grove K.L., Smith J.T. Leptin is not the critical signal for kisspeptin or luteinizing hormone restoration during exit from negative energy balance. J. Neuroendocrinol. 2011, 23:1099-1112.
15. Yura S., Itoh H., Sagawa N., Yamamoto H., Masuzaki H., Nakao K., Kawamura M., Takemura M., Kakui K., Ogawa Y., Fujii S. Role of premature leptin surge in obesity resulting from intrauterine undernutrition. Cell Metabol. 2005, 1:371-378.