Targeting of metastasis-promoting tumor-associated fibroblasts and modulation of pancreatic tumor-associated stroma with a carboxymethylcellulose-docetaxel nanoparticle

Journal of Controlled Release

Volumn 206, Issue , 2015, Pages 122-130

  Ernsting, Mark J ^a,b   Hoang, Bryan ^a   Lohse, Ines ^c   Undzys, Elijus ^a   Cao, Pinjiang ^c   Do, Trevor ^c   Gill, Bethany ^c   Pintilie, Melania ^c   Hedley, David ^c   Li, Shyh Dar ^a,d  

^a ONTARIO INSTITUTE FOR CANCER RESEARCH   (Canada)

^b RYERSON UNIVERSITY   (Canada)

^c PRINCESS MARGARET HOSPITAL   (Canada)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Nanoparticles; Pancreatic cancer; Tumor associated stroma

Indexed keywords

CELL CULTURE; CELL PROLIFERATION; CHEMOTHERAPY; CYTOLOGY; DISEASES; DRUG PRODUCTS; FIBROBLASTS; MAMMALS; MOBILE SECURITY; NANOPARTICLES; PATHOLOGY; PATIENT TREATMENT; PROTEINS;

CARBOXY METHYLCELLULOSE; CELLULAR INTERACTION; DUCTAL ADENOCARCINOMAS; INTRAVENOUS INJECTIONS; PANCREATIC CANCER XENOGRAFTS; PANCREATIC CANCERS; SMOOTH MUSCLE ACTINS; TUMOR PROGRESSIONS;

TUMORS;

CARBOXYMETHYLCELLULOSE; DOCETAXEL; GEMCITABINE; MACROGOL; NANOPARTICLE; PACLITAXEL; SMOOTH MUSCLE ACTIN; ANTINEOPLASTIC AGENT; MACROGOL DERIVATIVE; TAXOID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AQUEOUS SOLUTION; ARTICLE; CANCER CHEMOTHERAPY; CANCER INHIBITION; CELL DENSITY; CELL INTERACTION; CELL POPULATION; CONTROLLED STUDY; FEMALE; FIBROBLAST; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MALE; METASTASIS; METASTASIS POTENTIAL; MOUSE; NONHUMAN; PANCREAS CANCER; PANCREATIC CANCER CELL LINE; PHENOTYPE; PRIORITY JOURNAL; SINGLE DRUG DOSE; STROMA; STROMA CELL; TUMOR GROWTH; TUMOR XENOGRAFT; ANIMAL; C57BL MOUSE; CHEMISTRY; DRUG DELIVERY SYSTEM; DRUG EFFECTS; DRUG SCREENING; ECONOMICS; HUMAN; NEOPLASM METASTASIS; PANCREAS; PANCREATIC NEOPLASMS; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; CARBOXYMETHYLCELLULOSE SODIUM; CELL LINE, TUMOR; DRUG DELIVERY SYSTEMS; FEMALE; FIBROBLASTS; HUMANS; MICE; MICE, INBRED C57BL; NANOPARTICLES; NEOPLASM METASTASIS; PANCREAS; PANCREATIC NEOPLASMS; POLYETHYLENE GLYCOLS; TAXOIDS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84925769633     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.03.023     Document Type: Article

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