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Volumn 211, Issue 5, 2015, Pages 791-800

A single immunization with modified vaccinia virus Ankara-based influenza virus H7 vaccine affords protection in the influenza A(H7N9) pneumonia ferret model

Author keywords

Influenza A(H7N9) virus; Modified vaccinia virus Ankara; Vaccine

Indexed keywords

INFLUENZA VACCINE; DRUG CARRIER; HEMAGGLUTININ, AVIAN INFLUENZA A VIRUS; INFLUENZA VIRUS HEMAGGLUTININ;

EID: 84925757182     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiu528     Document Type: Article
Times cited : (28)

References (50)
  • 1
    • 84877785371 scopus 로고    scopus 로고
    • Human infection with a novel avian-origin influenza A (H7N9) virus
    • Gao R, Cao B, Hu Y, et al. Human infection with a novel avian-origin influenza A (H7N9) virus. N Engl J Med 2013;368:1888-97.
    • (2013) N Engl J Med , vol.368 , pp. 1888-1897
    • Gao, R.1    Cao, B.2    Hu, Y.3
  • 2
    • 84876828555 scopus 로고    scopus 로고
    • Preliminary report: Epidemiology of the avian influenza A (H7N9) outbreak in China
    • Li Q, Zhou L, Zhou M, et al. Preliminary report: epidemiology of the avian influenza A (H7N9) outbreak in China. N Engl J Med 2013;370:520-32.
    • (2013) N Engl J Med , vol.370 , pp. 520-532
    • Li, Q.1    Zhou, L.2    Zhou, M.3
  • 3
    • 84886686022 scopus 로고    scopus 로고
    • Human infection with avian influenza A (H7N9) virus re-emerges in China in winter 2013
    • Chen E, Chen Y, Fu L, et al. Human infection with avian influenza A (H7N9) virus re-emerges in China in winter 2013. Euro Surveill 2013;18:1-10.
    • (2013) Euro Surveill , vol.18 , pp. 1-10
    • Chen, E.1    Chen, Y.2    Fu, L.3
  • 5
    • 84898725844 scopus 로고    scopus 로고
    • H7N9: A low pathogenic avian influenza A virus infecting humans
    • Liu J, Xiao H, Wu Y, et al. H7N9: a low pathogenic avian influenza A virus infecting humans. Curr Opin Virol 2014;5c: 91-7.
    • (2014) Curr Opin Virol , vol.5 C , pp. 91-97
    • Liu, J.1    Xiao, H.2    Wu, Y.3
  • 6
    • 84884589399 scopus 로고    scopus 로고
    • Novel avian-origin influenza A (H7N9) virus attaches to epithelium in both upper and lower respiratory tract of humans
    • Van Riel D, Leijten LM, De Graaf M, et al. Novel avian-origin influenza A (H7N9) virus attaches to epithelium in both upper and lower respiratory tract of humans. Am J Pathol 2013;183:1137-43.
    • (2013) Am J Pathol , vol.183 , pp. 1137-1143
    • Van Riel, D.1    Leijten, L.M.2    De Graaf, M.3
  • 7
    • 84885172061 scopus 로고    scopus 로고
    • Low pathogenic avian influenza A (H7N9) virus causes high mortality in ferrets upon intratracheal challenge: A model to study intervention strategies
    • Kreijtz JH, Kroeze EJ, Stittelaar KJ, et al. Low pathogenic avian influenza A (H7N9) virus causes high mortality in ferrets upon intratracheal challenge: a model to study intervention strategies. Vaccine 2013;31:4995-9.
    • (2013) Vaccine , vol.31 , pp. 4995-4999
    • Kreijtz, J.H.1    Kroeze, E.J.2    Stittelaar, K.J.3
  • 10
    • 84871147732 scopus 로고    scopus 로고
    • Evaluations for in vitro correlates of immunogenicity of inactivated influenza a H5, H7 and H9 vaccines in humans
    • Couch RB, Decker WK, Utama B, et al. Evaluations for in vitro correlates of immunogenicity of inactivated influenza a H5, H7 and H9 vaccines in humans. PLoS One 2012;7:e50830.
    • (2012) PLoS One , vol.7 , pp. e50830
    • Couch, R.B.1    Decker, W.K.2    Utama, B.3
  • 11
    • 84878781144 scopus 로고    scopus 로고
    • Low immunogenicity predicted for emerging avian-origin H7N9: Implication for influenza vaccine design
    • De Groot AS, Ardito M, Terry F, et al. Low immunogenicity predicted for emerging avian-origin H7N9: implication for influenza vaccine design. Hum Vaccin Immunother 2013;9:950-6.
    • (2013) Hum Vaccin Immunother , vol.9 , pp. 950-956
    • De Groot, A.S.1    Ardito, M.2    Terry, F.3
  • 12
    • 84874605485 scopus 로고    scopus 로고
    • Risk of narcolepsy in children and young people receiving AS03 adjuvanted pandemic A/H1N1 2009 influenza vaccine: Retrospective analysis
    • Miller E, Andrews N, Stellitano L, et al. Risk of narcolepsy in children and young people receiving AS03 adjuvanted pandemic A/H1N1 2009 influenza vaccine: retrospective analysis. BMJ 2013;346:f794.
    • (2013) BMJ , vol.346 , pp. f794
    • Miller, E.1    Andrews, N.2    Stellitano, L.3
  • 13
    • 66749137687 scopus 로고    scopus 로고
    • Vaccination strategies and vaccine formulations for epidemic and pandemic influenza control
    • Kreijtz JH, Osterhaus AD, Rimmelzwaan GF. Vaccination strategies and vaccine formulations for epidemic and pandemic influenza control. Hum Vaccin 2009;5:126-35.
    • (2009) Hum Vaccin , vol.5 , pp. 126-135
    • Kreijtz, J.H.1    Osterhaus, A.D.2    Rimmelzwaan, G.F.3
  • 14
    • 84903906895 scopus 로고    scopus 로고
    • Optimal designs of an HA-based DNAvaccine against H7 subtype influenza viruses
    • Zhang L, Jia N, Li J, et al. Optimal designs of an HA-based DNAvaccine against H7 subtype influenza viruses. Hum Vaccin Immunother 2014;10:1949-58.
    • (2014) Hum Vaccin Immunother , vol.10 , pp. 1949-1958
    • Zhang, L.1    Jia, N.2    Li, J.3
  • 15
    • 84901398021 scopus 로고    scopus 로고
    • Potency of an inactivated influenza vaccine prepared from A/duck/Mongolia/119/2008 (H7N9) against the challenge with A/Anhui/1/2013 (H7N9)
    • Chu DH, Sakoda Y, Nishi T, et al. Potency of an inactivated influenza vaccine prepared from A/duck/Mongolia/119/2008 (H7N9) against the challenge with A/Anhui/1/2013 (H7N9). Vaccine 2014;32:3473-9.
    • (2014) Vaccine , vol.32 , pp. 3473-3479
    • Chu, D.H.1    Sakoda, Y.2    Nishi, T.3
  • 16
    • 84899955795 scopus 로고    scopus 로고
    • Protective immunity to H7N9 influenza viruses elicited by synthetic DNA vaccine
    • Yan J, Villarreal DO, Racine T, et al. Protective immunity to H7N9 influenza viruses elicited by synthetic DNA vaccine. Vaccine 2014;32:2833-42.
    • (2014) Vaccine , vol.32 , pp. 2833-2842
    • Yan, J.1    Villarreal, D.O.2    Racine, T.3
  • 18
    • 84880284754 scopus 로고    scopus 로고
    • Induction of cross-reactive antibodies to novel H7N9 influenza virus by recombinant Newcastle disease virus expressing a North American lineage H7 subtype hemagglutinin
    • Goff PH, Krammer F, Hai R, et al. Induction of cross-reactive antibodies to novel H7N9 influenza virus by recombinant Newcastle disease virus expressing a North American lineage H7 subtype hemagglutinin. J Virol 2013;87:8235-40.
    • (2013) J Virol , vol.87 , pp. 8235-8240
    • Goff, P.H.1    Krammer, F.2    Hai, R.3
  • 19
    • 84896979547 scopus 로고    scopus 로고
    • Divergent H7 immunogens offer protection from H7N9 virus challenge
    • Krammer F, Albrecht RA, Tan GS, et al. Divergent H7 immunogens offer protection from H7N9 virus challenge. J Virol 2014;88:3976-85.
    • (2014) J Virol , vol.88 , pp. 3976-3985
    • Krammer, F.1    Albrecht, R.A.2    Tan, G.S.3
  • 20
    • 84891014819 scopus 로고    scopus 로고
    • One-shot vaccination with an insect cell-derived low-dose influenza A H7 virus-like particle preparation protects mice against H7N9 challenge
    • Klausberger M, Wilde M, Palmberger D, et al. One-shot vaccination with an insect cell-derived low-dose influenza A H7 virus-like particle preparation protects mice against H7N9 challenge. Vaccine 2014;32:355-62.
    • (2014) Vaccine , vol.32 , pp. 355-362
    • Klausberger, M.1    Wilde, M.2    Palmberger, D.3
  • 21
    • 84896720205 scopus 로고    scopus 로고
    • Expression of functional recombinant hemagglutinin and neuraminidase proteins from the novel H7N9 influenza virus using the baculovirus expression system
    • Margine I, Palese P, Krammer F. Expression of functional recombinant hemagglutinin and neuraminidase proteins from the novel H7N9 influenza virus using the baculovirus expression system. J Vis Exp 2013;81:e51112.
    • (2013) J Vis Exp , vol.81 , pp. e51112
    • Margine, I.1    Palese, P.2    Krammer, F.3
  • 22
    • 84890932195 scopus 로고    scopus 로고
    • A recombinant viruslike particle influenza A (H7N9) vaccine
    • Fries LF, Smith GE, Glenn GM. A recombinant viruslike particle influenza A (H7N9) vaccine. N Engl J Med 2013;369:2564-6.
    • (2013) N Engl J Med , vol.369 , pp. 2564-2566
    • Fries, L.F.1    Smith, G.E.2    Glenn, G.M.3
  • 23
    • 84890936701 scopus 로고    scopus 로고
    • Rapid manufacture and release of a GMP batch of avian influenza A (H7N9) virus-like particle vaccine made using recombinant baculovirus-Sf9 insect cell culture technology
    • Hahn T, Courbron D, Hamer M, et al. Rapid manufacture and release of a GMP batch of avian influenza A (H7N9) virus-like particle vaccine made using recombinant baculovirus-Sf9 insect cell culture technology. Bioprocessing J 2013;12:4-17.
    • (2013) Bioprocessing J , vol.12 , pp. 4-17
    • Hahn, T.1    Courbron, D.2    Hamer, M.3
  • 25
    • 84882850376 scopus 로고    scopus 로고
    • Reflections on the early development of poxvirus vectors
    • Moss B. Reflections on the early development of poxvirus vectors. Vaccine 2013;31:4220-2.
    • (2013) Vaccine , vol.31 , pp. 4220-4222
    • Moss, B.1
  • 26
    • 65449126737 scopus 로고    scopus 로고
    • Candidate influenza vaccines based on re-combinant modified vaccinia virus Ankara
    • Rimmelzwaan GF, Sutter G. Candidate influenza vaccines based on re-combinant modified vaccinia virus Ankara. Expert Rev Vaccines 2009;8:447-54.
    • (2009) Expert Rev Vaccines , vol.8 , pp. 447-454
    • Rimmelzwaan, G.F.1    Sutter, G.2
  • 27
    • 58849152275 scopus 로고    scopus 로고
    • Recombinant modified vaccinia virus Ankara expressing the hemagglutinin gene confers protection against homologous and heterologous H5N1 influenza virus infections in macaques
    • Kreijtz JH, Suezer Y, De Mutsert G, et al. Recombinant modified vaccinia virus Ankara expressing the hemagglutinin gene confers protection against homologous and heterologous H5N1 influenza virus infections in macaques. J Infect Dis 2009;199:405-13.
    • (2009) J Infect Dis , vol.199 , pp. 405-413
    • Kreijtz, J.H.1    Suezer, Y.2    De Mutsert, G.3
  • 28
    • 70649090329 scopus 로고    scopus 로고
    • MVA-based H5N1 vaccine affords cross-clade protection in mice against influenza A/H5N1 viruses at low doses and after single immunization
    • Kreijtz JH, Suezer Y, De Mutsert G, et al. MVA-based H5N1 vaccine affords cross-clade protection in mice against influenza A/H5N1 viruses at low doses and after single immunization. PLoS One 2009;4:e7790.
    • (2009) PLoS One , vol.4 , pp. e7790
    • Kreijtz, J.H.1    Suezer, Y.2    De Mutsert, G.3
  • 29
    • 34248993551 scopus 로고    scopus 로고
    • Recombinant modified vaccinia virus Ankara-based vaccine induces protective immunity in mice against infection with influenza virus H5N1
    • Kreijtz JH, Suezer Y, Van Amerongen G, et al. Recombinant modified vaccinia virus Ankara-based vaccine induces protective immunity in mice against infection with influenza virus H5N1. J Infect Dis 2007;195:1598-606.
    • (2007) J Infect Dis , vol.195 , pp. 1598-1606
    • Kreijtz, J.H.1    Suezer, Y.2    Van Amerongen, G.3
  • 30
    • 40249119594 scopus 로고    scopus 로고
    • Protective efficacy of several vaccines against highly pathogenic H5N1 avian influenza virus under experimental conditions
    • Veits J, Romer-Oberdorfer A, Helferich D, et al. Protective efficacy of several vaccines against highly pathogenic H5N1 avian influenza virus under experimental conditions. Vaccine 2008;26:1688-96.
    • (2008) Vaccine , vol.26 , pp. 1688-1696
    • Veits, J.1    Romer-Oberdorfer, A.2    Helferich, D.3
  • 31
    • 79551569177 scopus 로고    scopus 로고
    • Vectors based on modified vaccinia Ankara expressing influenza H5N1 hemagglutinin induce substantial cross-clade protective immunity
    • Hessel A, Schwendinger M, Holzer GW, et al. Vectors based on modified vaccinia Ankara expressing influenza H5N1 hemagglutinin induce substantial cross-clade protective immunity. PLoS One 2011;6:e16247.
    • (2011) PLoS One , vol.6 , pp. e16247
    • Hessel, A.1    Schwendinger, M.2    Holzer, G.W.3
  • 32
    • 0028074787 scopus 로고
    • A recombinant vector derived from the host range-restricted and highly attenuated MVA strain of vaccinia virus stimulates protective immunity in mice to influenza virus
    • Sutter G, Wyatt LS, Foley PL, Bennink JR, Moss B. A recombinant vector derived from the host range-restricted and highly attenuated MVA strain of vaccinia virus stimulates protective immunity in mice to influenza virus. Vaccine 1994;12:1032-40.
    • (1994) Vaccine , vol.12 , pp. 1032-1040
    • Sutter, G.1    Wyatt, L.S.2    Foley, P.L.3    Bennink, J.R.4    Moss, B.5
  • 33
    • 79951645476 scopus 로고    scopus 로고
    • Potent CD8+ T-cell immuno-genicity in humans of a novel heterosubtypic influenza Avaccine, MVA-NP+M1
    • Berthoud TK, Hamill M, Lillie PJ, et al. Potent CD8+ T-cell immuno-genicity in humans of a novel heterosubtypic influenza Avaccine, MVA-NP+M1. Clin Infect Dis 2011;52:1-7.
    • (2011) Clin Infect Dis , vol.52 , pp. 1-7
    • Berthoud, T.K.1    Hamill, M.2    Lillie, P.J.3
  • 34
    • 84895733615 scopus 로고    scopus 로고
    • MVA vectors expressing conserved influenza proteins protect mice against lethal challenge with H5N1, H9N2 and H7N1 viruses
    • Hessel A, Savidis-Dacho H, Coulibaly S, et al. MVA vectors expressing conserved influenza proteins protect mice against lethal challenge with H5N1, H9N2 and H7N1 viruses. PLoS One 2014;9:e88340.
    • (2014) PLoS One , vol.9 , pp. e88340
    • Hessel, A.1    Savidis-Dacho, H.2    Coulibaly, S.3
  • 35
    • 84875260632 scopus 로고    scopus 로고
    • Cross-protective immunity against multiple influenza virus subtypes by a novel modified vaccinia Ankara (MVA) vectored vaccine in mice
    • Brewoo JN, Powell TD, Jones JC, et al. Cross-protective immunity against multiple influenza virus subtypes by a novel modified vaccinia Ankara (MVA) vectored vaccine in mice. Vaccine 2013;31:1848-55.
    • (2013) Vaccine , vol.31 , pp. 1848-1855
    • Brewoo, J.N.1    Powell, T.D.2    Jones, J.C.3
  • 37
    • 3042689422 scopus 로고    scopus 로고
    • Multiprotein HIV type 1 clade B DNA and MVA vaccines: Construction, expression, and immunogenicity in rodents of the MVA component
    • Wyatt LS, Earl PL, Liu JY, et al. Multiprotein HIV type 1 clade B DNA and MVA vaccines: construction, expression, and immunogenicity in rodents of the MVA component. AIDS Res Hum Retroviruses 2004;20:645-53.
    • (2004) AIDS Res Hum Retroviruses , vol.20 , pp. 645-653
    • Wyatt, L.S.1    Earl, P.L.2    Liu, J.Y.3
  • 38
    • 0031866073 scopus 로고    scopus 로고
    • Comparison of RNA hybridization, hemagglutination assay, titration of infectious virus and immunofluorescence as methods for monitoring influenza virus replication in vitro
    • Rimmelzwaan GF, Baars M, Claas EC, Osterhaus AD. Comparison of RNA hybridization, hemagglutination assay, titration of infectious virus and immunofluorescence as methods for monitoring influenza virus replication in vitro. J Virol Methods 1998;74:57-66.
    • (1998) J Virol Methods , vol.74 , pp. 57-66
    • Rimmelzwaan, G.F.1    Baars, M.2    Claas, E.C.3    Osterhaus, A.D.4
  • 39
    • 0002733214 scopus 로고
    • Haemagglutination inhibition test. Advanced laboratory techniques for influenza diagnosis
    • Atlanta: US Department of Health, Education, and Welfare
    • Palmer D, Dowle W, Coleman M, Schild G. Haemagglutination inhibition test. Advanced laboratory techniques for influenza diagnosis. Procedural Guide. Atlanta: US Department of Health, Education, and Welfare, 1975:25-62.
    • (1975) Procedural Guide , pp. 25-62
    • Palmer, D.1    Dowle, W.2    Coleman, M.3    Schild, G.4
  • 40
    • 77951825335 scopus 로고    scopus 로고
    • Recipients of vaccine against the 1976 "swine flu" have enhanced neutralization responses to the 2009 novel H1N1 influenza virus
    • McCullers JA, Van De Velde LA, Allison KJ, Branum KC, Webby RJ, Flynn PM. Recipients of vaccine against the 1976 "swine flu" have enhanced neutralization responses to the 2009 novel H1N1 influenza virus. Clin Infect Dis 2010;50:1487-92.
    • (2010) Clin Infect Dis , vol.50 , pp. 1487-1492
    • McCullers, J.A.1    Van De Velde, L.A.2    Allison, K.J.3    Branum, K.C.4    Webby, R.J.5    Flynn, P.M.6
  • 41
    • 78049375271 scopus 로고    scopus 로고
    • Evaluation of a modified vaccinia virus Ankara (MVA)-based candidate pandemic influenza A/H1N1 vaccine in the ferret model
    • Kreijtz JH, Suzer Y, Bodewes R, et al. Evaluation of a modified vaccinia virus Ankara (MVA)-based candidate pandemic influenza A/H1N1 vaccine in the ferret model. J Gen Virol 2010;91:2745-52.
    • (2010) J Gen Virol , vol.91 , pp. 2745-2752
    • Kreijtz, J.H.1    Suzer, Y.2    Bodewes, R.3
  • 42
    • 79952411472 scopus 로고    scopus 로고
    • Efficacy of vaccination with different combinations of MF59-adjuvanted and nonadju-vanted seasonal and pandemic influenza vaccines against pandemic H1N1 (2009) influenza virus infection in ferrets
    • Van Den Brand JM, Kreijtz JH, Bodewes R, et al. Efficacy of vaccination with different combinations of MF59-adjuvanted and nonadju-vanted seasonal and pandemic influenza vaccines against pandemic H1N1 (2009) influenza virus infection in ferrets. J Virol 2011;85:2851-8.
    • (2011) J Virol , vol.85 , pp. 2851-2858
    • Van Den Brand, J.M.1    Kreijtz, J.H.2    Bodewes, R.3
  • 43
    • 80051771826 scopus 로고    scopus 로고
    • Pathogenesis of influenza A/H5N1 virus infection in ferrets differs between intranasal and intratracheal routes of inoculation
    • Bodewes R, Kreijtz JH, Van Amerongen G, et al. Pathogenesis of influenza A/H5N1 virus infection in ferrets differs between intranasal and intratracheal routes of inoculation. Am J Pathol 2011;179:30-6.
    • (2011) Am J Pathol , vol.179 , pp. 30-36
    • Bodewes, R.1    Kreijtz, J.H.2    Van Amerongen, G.3
  • 44
    • 84858374093 scopus 로고    scopus 로고
    • The multibasic cleavage site in H5N1 virus is critical for systemic spread along the olfactory and hematogenous routes in ferrets
    • Schrauwen EJ, Herfst S, Leijten LM, et al. The multibasic cleavage site in H5N1 virus is critical for systemic spread along the olfactory and hematogenous routes in ferrets. J Virol 2012;86:3975-84.
    • (2012) J Virol , vol.86 , pp. 3975-3984
    • Schrauwen, E.J.1    Herfst, S.2    Leijten, L.M.3
  • 45
    • 70349974553 scopus 로고    scopus 로고
    • Preclinical evaluation of a modified vaccinia virus Ankara (MVA)-based vaccine against influenza A/H5N1 viruses
    • Kreijtz JH, Suezer Y, De Mutsert G, et al. Preclinical evaluation of a modified vaccinia virus Ankara (MVA)-based vaccine against influenza A/H5N1 viruses. Vaccine 2009;27:6296-9.
    • (2009) Vaccine , vol.27 , pp. 6296-6299
    • Kreijtz, J.H.1    Suezer, Y.2    De Mutsert, G.3
  • 46
    • 84885672963 scopus 로고    scopus 로고
    • Limited airborne transmission of H7N9 influenza A virus between ferrets
    • Richard M, Schrauwen EJ, De Graaf M, et al. Limited airborne transmission of H7N9 influenza A virus between ferrets. Nature 2013;501:560-3.
    • (2013) Nature , vol.501 , pp. 560-563
    • Richard, M.1    Schrauwen, E.J.2    De Graaf, M.3
  • 47
    • 84893242791 scopus 로고    scopus 로고
    • Novel avian-origin human influenza A (H7N9) can be transmitted between ferrets via respiratory droplets
    • Xu L, Bao L, Deng W, et al. Novel avian-origin human influenza A (H7N9) can be transmitted between ferrets via respiratory droplets. J Infect Dis 2014;209:551-6.
    • (2014) J Infect Dis , vol.209 , pp. 551-556
    • Xu, L.1    Bao, L.2    Deng, W.3
  • 48
    • 84901343287 scopus 로고    scopus 로고
    • Development of a high-yield live attenuated H7N9 influenza virus vaccine that provides protection against homologous and heterologous H7 wild-type viruses in ferrets
    • Chen Z, Baz M, Lu J, et al. Development of a high-yield live attenuated H7N9 influenza virus vaccine that provides protection against homologous and heterologous H7 wild-type viruses in ferrets. J Virol 2014;88:7016-23.
    • (2014) J Virol , vol.88 , pp. 7016-7023
    • Chen, Z.1    Baz, M.2    Lu, J.3
  • 49
    • 84885123699 scopus 로고    scopus 로고
    • Evaluation of live attenuated H7N3 and H7N7 vaccine viruses for their receptor binding preferences, immunogenicity in ferrets and cross reactivity to the novel H7N9 virus
    • Xu Q, Chen Z, Cheng X, Xu L, Jin H. Evaluation of live attenuated H7N3 and H7N7 vaccine viruses for their receptor binding preferences, immunogenicity in ferrets and cross reactivity to the novel H7N9 virus. PLoS One 2013;8:e76884.
    • (2013) PLoS One , vol.8 , pp. e76884
    • Xu, Q.1    Chen, Z.2    Cheng, X.3    Xu, L.4    Jin, H.5
  • 50
    • 77955553009 scopus 로고    scopus 로고
    • Repository of Eurasian influenza A virus hemagglutinin and neuraminidase reverse genetics vectors and recombinant viruses
    • Keawcharoen J, Spronken MI, Vuong O, et al. Repository of Eurasian influenza A virus hemagglutinin and neuraminidase reverse genetics vectors and recombinant viruses. Vaccine 2010;28:5803-9.
    • (2010) Vaccine , vol.28 , pp. 5803-5809
    • Keawcharoen, J.1    Spronken, M.I.2    Vuong, O.3


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