Epidermal growth factor receptor (EGFR) signaling requires a specific endoplasmic reticulum thioredoxin for the post-translational control of receptor presentation to the cell surface

Journal of Biological Chemistry

Volumn 290, Issue 13, 2015, Pages 8016-8027

  Dong, Aiwen ^a   Wodziak, Dariusz ^a   Lowe, Anson W ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL MEMBRANES; DISEASES; SIGNAL TRANSDUCTION;

CANCER CELL LINES; CELL SURFACES; ENDOPLASMIC RETICULUM; EPIDERMAL GROWTH FACTOR RECEPTORS; PROTEIN FUNCTIONS; REGULATORY MECHANISM; THERAPEUTIC TARGETS; THIOREDOXINS;

CELL SIGNALING;

ANTERIOR GRADIENT HOMOLOG 2 PROTEIN; CELL PROTEIN; CYSTEINE; DISULFIDE; EARLY GROWTH RESPONSE FACTOR 1; EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN FOS; PROTEIN TYROSINE KINASE INHIBITOR; THIOREDOXIN; UNCLASSIFIED DRUG; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; AGR2 PROTEIN, HUMAN; CYSTINE; EGFR PROTEIN, HUMAN; PROTEIN; PROTEIN KINASE INHIBITOR; QUINAZOLINE DERIVATIVE; TYRPHOSTIN;

A431 CELL LINE; ARTICLE; CANCER CELL LINE; CANCER PROGNOSIS; CELL FRACTIONATION; CELL SURFACE; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; LETHALITY; NCI H460 CELL LINE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; CELL MEMBRANE; CHO CELL LINE; CRICETULUS; HAMSTER; METABOLISM; PROTEIN TRANSPORT; TRANSGENIC MOUSE; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CELL MEMBRANE; CHO CELLS; CRICETINAE; CRICETULUS; CYSTINE; ENDOPLASMIC RETICULUM; HUMANS; MICE, INBRED C57BL; MICE, TRANSGENIC; PROTEIN KINASE INHIBITORS; PROTEIN TRANSPORT; PROTEINS; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; THIOREDOXINS; TYRPHOSTINS;

EID: 84925706069     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.623207     Document Type: Article

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