-
1
-
-
84964875910
-
-
[Last accessed on 22 August 2014]
-
GLOBOCAN. Available from: www. globocan.iarc.fr [Last accessed on 22 August 2014]
-
GLOBOCAN
-
-
-
2
-
-
84905504624
-
Clinical utility of erlotinib for the treatment of non-small-cell lung cancer in Japanese patients: Current evidence
-
Togashi Y, Hayashi H, Nakagawa K, Nishio K. Clinical utility of erlotinib for the treatment of non-small-cell lung cancer in Japanese patients: current evidence. Drug Des Devel Ther 2014;8:1037
-
(2014)
Drug des Devel Ther
, vol.8
, pp. 1037
-
-
Togashi, Y.1
Hayashi, H.2
Nakagawa, K.3
Nishio, K.4
-
3
-
-
84883556206
-
Epidermal growth factor receptor tyrosine kinase inhibitors as initial therapy for non-small cell lung cancer: Focus on epidermal growth factor receptor mutation testing and mutation-positive patients
-
Roengvoraphoj M, Tsongalis GJ, Dragnev KH, Rigas JR. Epidermal growth factor receptor tyrosine kinase inhibitors as initial therapy for non-small cell lung cancer: focus on epidermal growth factor receptor mutation testing and mutation-positive patients. Cancer Treat Rev 2013;39(8):839-50
-
(2013)
Cancer Treat Rev
, vol.39
, Issue.8
, pp. 839-850
-
-
Roengvoraphoj, M.1
Tsongalis, G.J.2
Dragnev, K.H.3
Rigas, J.R.4
-
4
-
-
84907554821
-
Risk of selected gastrointestinal toxicities in breast cancer patients treated with regimens containing lapatinib; A pooled analysis of randomized controlled studies
-
Abdel-Rahman O, Fouad M. Risk of selected gastrointestinal toxicities in breast cancer patients treated with regimens containing lapatinib; a pooled analysis of randomized controlled studies. Expert Rev Anticancer Ther 2014(0):1-14
-
(2014)
Expert Rev Anticancer Ther
, pp. 1-14
-
-
Abdel-Rahman, O.1
Fouad, M.2
-
5
-
-
65349188890
-
Erlotinib-induced skin rash in patients with non-small-cell lung cancer: Pathogenesis, clinical significance, and management
-
Tsimboukis S, Merikas I, Karapanagiotou EM, et al. Erlotinib-induced skin rash in patients with non-small-cell lung cancer: pathogenesis, clinical significance, and management. Clin Lung Cancer 2009;10(2):106-11
-
(2009)
Clin Lung Cancer
, vol.10
, Issue.2
, pp. 106-111
-
-
Tsimboukis, S.1
Merikas, I.2
Karapanagiotou, E.M.3
-
6
-
-
4344646459
-
Determinants of tumor response and survival with erlotinib in patients with non-small-cell lung cancer
-
Perez-Soler R, Chachoua A, Hammond LA, et al. Determinants of tumor response and survival with erlotinib in patients with non-small-cell lung cancer. J Clin Oncol 2004;22(16):3238-47
-
(2004)
J Clin Oncol
, vol.22
, Issue.16
, pp. 3238-3247
-
-
Perez-Soler, R.1
Chachoua, A.2
Hammond, L.A.3
-
7
-
-
84856058201
-
Pulmonary toxicities from targeted therapies: A review
-
Barber NA, Ganti AK. Pulmonary toxicities from targeted therapies: a review. Targeted oncology 2011;6(4):235-43
-
(2011)
Targeted Oncology
, vol.6
, Issue.4
, pp. 235-243
-
-
Barber, N.A.1
Ganti, A.K.2
-
8
-
-
84925548115
-
Preferred reporting items for systematic reviews and meta-analyses: The PRISMA Statement
-
PRISMA Group
-
Moher D, Liberati A, Tetzlaff J, Altman DG; PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: The PRISMA Statement. J Clin Epidemiol 2009;62(10):1006-12
-
(2009)
J Clin Epidemiol
, vol.62
, Issue.10
, pp. 1006-1012
-
-
Moher, D.1
Liberati, A.2
Tetzlaff, J.3
Altman, D.G.4
-
9
-
-
84871473159
-
-
[Accessed on 20 November 2014]
-
National cancer institute. Common toxicity criteria. Available from: http://ctep.cancer. gov/protocoldevelopment/electronic-applications/docs/ctcaev3.pdf. [Accessed on 20 November 2014]
-
National Cancer Institute. Common Toxicity Criteria
-
-
-
10
-
-
75249084998
-
Randomized, placebo-controlled, phase II study of sequential erlotinib and chemotherapy as first-line treatment for advanced non-small-cell lung cancer
-
Mok TS, Wu YL, Yu CJ, et al. Randomized, placebo-controlled, phase II study of sequential erlotinib and chemotherapy as first-line treatment for advanced non-small-cell lung cancer. J Clin Oncol 2009;27(30):5080-7
-
(2009)
J Clin Oncol
, vol.27
, Issue.30
, pp. 5080-5087
-
-
Mok, T.S.1
Wu, Y.L.2
Yu, C.J.3
-
11
-
-
39749087795
-
Randomized phase II trial of erlotinib or standard chemotherapy in patients with advanced non-small-cell lung cancer and a performance status of 2
-
Lilenbaum R, Axelrod R, Thomas S, et al. Randomized phase II trial of erlotinib or standard chemotherapy in patients with advanced non-small-cell lung cancer and a performance status of 2. J Clin Oncol 2008; 26(6):863-9
-
(2008)
J Clin Oncol
, vol.26
, Issue.6
, pp. 863-869
-
-
Lilenbaum, R.1
Axelrod, R.2
Thomas, S.3
-
12
-
-
34248140107
-
Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non-small-cell lung cancer: The Tarceva lung cancer investigation Trial
-
Gatzemeier U, Pluzanska A, Szczesna A, et al. Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non-small-cell lung cancer: the Tarceva lung cancer investigation Trial. J Clin Oncol 2007;25(12):1545-52
-
(2007)
J Clin Oncol
, vol.25
, Issue.12
, pp. 1545-1552
-
-
Gatzemeier, U.1
Pluzanska, A.2
Szczesna, A.3
-
13
-
-
66249097440
-
A prospective pharmacogenomic (PG), pharmacodynamic (PD), and pharmacokinetic (PK) study of determinants of erlotinib toxicity
-
Rudin CM, Desai AA, Janisch L, et al. A prospective pharmacogenomic (PG), pharmacodynamic (PD), and pharmacokinetic (PK) study of determinants of erlotinib toxicity. J Clin Oncol 2006;24:3080
-
(2006)
J Clin Oncol
, vol.24
, pp. 3080
-
-
Rudin, C.M.1
Desai, A.A.2
Janisch, L.3
-
14
-
-
84925683938
-
-
[Last accessed on 29 August 2014]
-
TARCEVA. Available from: www.gene.com/download/pdf/tarceva-prescribing.pdf [Last accessed on 29 August 2014]
-
TARCEVA
-
-
-
15
-
-
84872099847
-
-
[Last accessed on 29 August 2014]
-
PRODUCT MONOGRAPH. Available from: http://hemonc.org/docs/packageinsert/gefitinib.pdf [Last accessed on 29 August 2014]
-
Product Monograph
-
-
-
16
-
-
83555166254
-
Randomized phase II study of gefitinib versus erlotinib in patients with advanced non-small cell lung cancer who failed previous chemotherapy
-
Kim ST, Uhm JE, Lee J, et al. Randomized phase II study of gefitinib versus erlotinib in patients with advanced non-small cell lung cancer who failed previous chemotherapy. Lung Cancer 2012;75(1):82-8
-
(2012)
Lung Cancer
, vol.75
, Issue.1
, pp. 82-88
-
-
Kim, S.T.1
Uhm, J.E.2
Lee, J.3
-
17
-
-
84862785051
-
Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): A phase 2b/3 randomised trial
-
Miller VA, Hirsh V, Cadranel J, et al. Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): a phase 2b/3 randomised trial. Lancet Oncol 2012;13(5):528-38
-
(2012)
Lancet Oncol
, vol.13
, Issue.5
, pp. 528-538
-
-
Miller, V.A.1
Hirsh, V.2
Cadranel, J.3
-
18
-
-
84885575248
-
Risk of oral and gastrointestinal mucosal injury among patients receiving selected targeted agents: A meta-analysis
-
Elting LS, Chang YC, Parelkar P, et al. Risk of oral and gastrointestinal mucosal injury among patients receiving selected targeted agents: a meta-analysis. Support Care Cancer 2013;21(11):3243-54
-
(2013)
Support Care Cancer
, vol.21
, Issue.11
, pp. 3243-3254
-
-
Elting, L.S.1
Chang, Y.C.2
Parelkar, P.3
-
19
-
-
84891656497
-
ATLAS: Randomized, double-blind, placebo-controlled, phase IIIB trial comparing bevacizumab therapy with or without erlotinib, after completion of chemotherapy, with bevacuzimab for first-line treatment of advanced non-smallcell-lung cancer
-
Johnson BE, Kabbinavar F, Fehrenbacher L, et al. ATLAS: randomized, double-blind, placebo-controlled, phase IIIB trial comparing bevacizumab therapy with or without erlotinib, after completion of chemotherapy, with bevacuzimab for first-line treatment of advanced non-smallcell-lung cancer. J Clin Oncol 2013;31: 3926-34
-
(2013)
J Clin Oncol
, vol.31
, pp. 3926-3934
-
-
Johnson, B.E.1
Kabbinavar, F.2
Fehrenbacher, L.3
-
20
-
-
84884906715
-
Three-arm randomised controlled phase 2 study comparing pemetrexed and erlotinib to either pemetrexed or erlotinib alone as second-line treatment for never-smokers with non-squamous non-small cell lung cancer
-
Lee DH, Lee JS, Kim SW, et al. Three-arm randomised controlled phase 2 study comparing pemetrexed and erlotinib to either pemetrexed or erlotinib alone as second-line treatment for never-smokers with non-squamous non-small cell lung cancer. Eur J Cancer 2013;49(15):3111-21
-
(2013)
Eur J Cancer
, vol.49
, Issue.15
, pp. 3111-3121
-
-
Lee, D.H.1
Lee, J.S.2
Kim, S.W.3
-
21
-
-
84883055532
-
Erlotinib versus docetaxel as second-line treatment of patients with advanced non-small-cell lung cancer and wild-type EGFR tumours (TAILOR): A randomised controlled trial
-
Garassino MC, Martelli O, Broggini M, et al. Erlotinib versus docetaxel as second-line treatment of patients with advanced non-small-cell lung cancer and wild-type EGFR tumours (TAILOR): a randomised controlled trial. Lancet Oncol 2013;14(10):981-8
-
(2013)
Lancet Oncol
, vol.14
, Issue.10
, pp. 981-988
-
-
Garassino, M.C.1
Martelli, O.2
Broggini, M.3
-
22
-
-
84879784343
-
Intercalated combination of chemotherapy and erlotinib for patients with advanced stage non-small-cell lung cancer (FASTACT-2): A randomised, double-blind trial
-
Wu YL, Lee JS, Thongprasert S, et al. Intercalated combination of chemotherapy and erlotinib for patients with advanced stage non-small-cell lung cancer (FASTACT-2): a randomised, double-blind trial. Lancet Oncol 2013;14(8):777-86
-
(2013)
Lancet Oncol
, vol.14
, Issue.8
, pp. 777-786
-
-
Wu, Y.L.1
Lee, J.S.2
Thongprasert, S.3
-
23
-
-
84880570204
-
Pemetrexed versus erlotinib in pretreated patients with advanced non-small cell lung cancer: A Hellenic Oncology Research Group (HORG) randomized phase 3 study
-
Karampeazis A, Voutsina A, Souglakos J, et al. Pemetrexed versus erlotinib in pretreated patients with advanced non-small cell lung cancer: a Hellenic Oncology Research Group (HORG) randomized phase 3 study. Cancer 2013;119(15): 2754-64
-
(2013)
Cancer
, vol.119
, Issue.15
, pp. 2754-2764
-
-
Karampeazis, A.1
Voutsina, A.2
Souglakos, J.3
-
24
-
-
84868192444
-
First-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy (TOPICAL): A double-blind, placebo-controlled, phase 3 trial
-
Lee SM, Khan I, Upadhyay S, et al. First-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy (TOPICAL): a double-blind, placebo-controlled, phase 3 trial. Lancet Oncol 2012;13:1161-70
-
(2012)
Lancet Oncol
, vol.13
, pp. 1161-1170
-
-
Lee, S.M.1
Khan, I.2
Upadhyay, S.3
-
25
-
-
84867059528
-
Randomized, Phase III study of gemcitabine or erlotinib maintenance therapy versus observation, with predefined second-line treatment, after cisplatin-gemcitabine induction chemotherapy in advanced non-small-cell lung cancer
-
Perol M, Chouaid C, Perol D, et al. Randomized, Phase III study of gemcitabine or erlotinib maintenance therapy versus observation, with predefined second-line treatment, after cisplatin-gemcitabine induction chemotherapy in advanced non-small-cell lung cancer. J Clin Oncol 2012;30:3516-24
-
(2012)
J Clin Oncol
, vol.30
, pp. 3516-3524
-
-
Perol, M.1
Chouaid, C.2
Perol, D.3
-
26
-
-
84865334851
-
A multi-centre randomized, open-label phase II trial of continuous erlotinib plus gemcitabine or gemcitabine as first-line therapy in ECOG PS2 patients with advanced non-small cell lung cancer
-
Michael M, Pavlakis N, Clingan P, et al. A multi-centre randomized, open-label phase II trial of continuous erlotinib plus gemcitabine or gemcitabine as first-line therapy in ECOG PS2 patients with advanced non-small cell lung cancer. Oncol Rep 2012;28(3):763-7
-
(2012)
Oncol Rep
, vol.28
, Issue.3
, pp. 763-767
-
-
Michael, M.1
Pavlakis, N.2
Clingan, P.3
-
27
-
-
84857502654
-
Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): A multicentre, open-label, randomised phase 3 trial
-
Rosell R, Carcereny E, Gervais R, et al. Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial. Lancet Oncol 2012;13(3): 239-46
-
(2012)
Lancet Oncol
, vol.13
, Issue.3
, pp. 239-246
-
-
Rosell, R.1
Carcereny, E.2
Gervais, R.3
-
28
-
-
84857501696
-
Efficacy and safety of erlotinib versus chemotherapy in second-line treatment of patients with advanced, non-small-cell lung cancer with poor prognosis (TITAN): A randomized multicentre, open-label, phase 3 study
-
Ciuleanu T, Stelmakh L, Cicenas S, et al. Efficacy and safety of erlotinib versus chemotherapy in second-line treatment of patients with advanced, non-small-cell lung cancer with poor prognosis (TITAN): a randomized multicentre, open-label, phase 3 study. Lancet Oncol 2012;13(3): 300-8
-
(2012)
Lancet Oncol
, vol.13
, Issue.3
, pp. 300-308
-
-
Ciuleanu, T.1
Stelmakh, L.2
Cicenas, S.3
-
29
-
-
84858339030
-
Phase II randomized trial of erlotinib or vinorelbine in chemonaive, advanced, non-small cell lung cancer patients aged 70 years or older
-
Chen YM, Tsai CM, Fan WC, et al. Phase II randomized trial of erlotinib or vinorelbine in chemonaive, advanced, non-small cell lung cancer patients aged 70 years or older. J Thorac Oncol 2012; 7(2):412-18
-
(2012)
J Thorac Oncol
, vol.7
, Issue.2
, pp. 412-418
-
-
Chen, Y.M.1
Tsai, C.M.2
Fan, W.C.3
-
30
-
-
79960889662
-
Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): A multicentre, open-label, randomised, phase 3 study
-
Zhou C, Wu YL, Chen G, et al. Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study. Lancet Oncol 2011;12(8):735-42
-
(2011)
Lancet Oncol
, vol.12
, Issue.8
, pp. 735-742
-
-
Zhou, C.1
Wu, Y.L.2
Chen, G.3
-
31
-
-
80052273497
-
A randomized phase II trial of first-line treatment with gemcitabine, erlotinib, or gemcitabine and erlotinib in elderly patients (age ≥70 years) with stage IIIB/IV non-small cell lung cancer
-
Stinchcombe TE, Peterman AH, Lee CB, et al. A randomized phase II trial of first-line treatment with gemcitabine, erlotinib, or gemcitabine and erlotinib in elderly patients (age ≥70 years) with stage IIIB/IV non-small cell lung cancer. J ThoracOncol 2011;6(9):1569-77
-
(2011)
J ThoracOncol
, vol.6
, Issue.9
, pp. 1569-1577
-
-
Stinchcombe, T.E.1
Peterman, A.H.2
Lee, C.B.3
-
32
-
-
77953541527
-
Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: A multicentre, randomised, placebo-controlled phase 3 study
-
Cappuzzo F, Ciuleanu T, Stelmakh L, et al. Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study. Lancet Oncol 2010;11(6):521-9
-
(2010)
Lancet Oncol
, vol.11
, Issue.6
, pp. 521-529
-
-
Cappuzzo, F.1
Ciuleanu, T.2
Stelmakh, L.3
-
33
-
-
24944440830
-
TRIBUTE: A phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer
-
Herbst RS, Prager D, Hermann R, et al. TRIBUTE: a phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer. J Clin Oncol 2005;23(25):5892-9
-
(2005)
J Clin Oncol
, vol.23
, Issue.25
, pp. 5892-5899
-
-
Herbst, R.S.1
Prager, D.2
Hermann, R.3
-
34
-
-
22044445517
-
Erlotinib in previously treated non-small-cell lung cancer
-
Shepherd FA, Rodrigues Pereira J, Ciuleanu T, et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 2005;353(2):123-32
-
(2005)
N Engl J Med
, vol.353
, Issue.2
, pp. 123-132
-
-
Shepherd, F.A.1
Rodrigues Pereira, J.2
Ciuleanu, T.3
|