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Volumn 15, Issue 4, 2015, Pages 465-475

Risk of selected gastrointestinal toxicities in patients with advanced non-small cell lung cancer receiving erlotinib: A systematic review and meta-analysis

Author keywords

diarrhea; erlotinib; meta analysis; NSCLC; stomatitis

Indexed keywords

BEVACIZUMAB; CARBOPLATIN; CISPLATIN; DOCETAXEL; ERLOTINIB; GEMCITABINE; NAVELBINE; PACLITAXEL; PEMETREXED; PLACEBO; ANTINEOPLASTIC AGENT; PROTEIN KINASE INHIBITOR;

EID: 84925684764     PISSN: 14737140     EISSN: 17448328     Source Type: Journal    
DOI: 10.1586/14737140.2015.1014035     Document Type: Review
Times cited : (14)

References (34)
  • 1
    • 84964875910 scopus 로고    scopus 로고
    • [Last accessed on 22 August 2014]
    • GLOBOCAN. Available from: www. globocan.iarc.fr [Last accessed on 22 August 2014]
    • GLOBOCAN
  • 2
    • 84905504624 scopus 로고    scopus 로고
    • Clinical utility of erlotinib for the treatment of non-small-cell lung cancer in Japanese patients: Current evidence
    • Togashi Y, Hayashi H, Nakagawa K, Nishio K. Clinical utility of erlotinib for the treatment of non-small-cell lung cancer in Japanese patients: current evidence. Drug Des Devel Ther 2014;8:1037
    • (2014) Drug des Devel Ther , vol.8 , pp. 1037
    • Togashi, Y.1    Hayashi, H.2    Nakagawa, K.3    Nishio, K.4
  • 3
    • 84883556206 scopus 로고    scopus 로고
    • Epidermal growth factor receptor tyrosine kinase inhibitors as initial therapy for non-small cell lung cancer: Focus on epidermal growth factor receptor mutation testing and mutation-positive patients
    • Roengvoraphoj M, Tsongalis GJ, Dragnev KH, Rigas JR. Epidermal growth factor receptor tyrosine kinase inhibitors as initial therapy for non-small cell lung cancer: focus on epidermal growth factor receptor mutation testing and mutation-positive patients. Cancer Treat Rev 2013;39(8):839-50
    • (2013) Cancer Treat Rev , vol.39 , Issue.8 , pp. 839-850
    • Roengvoraphoj, M.1    Tsongalis, G.J.2    Dragnev, K.H.3    Rigas, J.R.4
  • 4
    • 84907554821 scopus 로고    scopus 로고
    • Risk of selected gastrointestinal toxicities in breast cancer patients treated with regimens containing lapatinib; A pooled analysis of randomized controlled studies
    • Abdel-Rahman O, Fouad M. Risk of selected gastrointestinal toxicities in breast cancer patients treated with regimens containing lapatinib; a pooled analysis of randomized controlled studies. Expert Rev Anticancer Ther 2014(0):1-14
    • (2014) Expert Rev Anticancer Ther , pp. 1-14
    • Abdel-Rahman, O.1    Fouad, M.2
  • 5
    • 65349188890 scopus 로고    scopus 로고
    • Erlotinib-induced skin rash in patients with non-small-cell lung cancer: Pathogenesis, clinical significance, and management
    • Tsimboukis S, Merikas I, Karapanagiotou EM, et al. Erlotinib-induced skin rash in patients with non-small-cell lung cancer: pathogenesis, clinical significance, and management. Clin Lung Cancer 2009;10(2):106-11
    • (2009) Clin Lung Cancer , vol.10 , Issue.2 , pp. 106-111
    • Tsimboukis, S.1    Merikas, I.2    Karapanagiotou, E.M.3
  • 6
    • 4344646459 scopus 로고    scopus 로고
    • Determinants of tumor response and survival with erlotinib in patients with non-small-cell lung cancer
    • Perez-Soler R, Chachoua A, Hammond LA, et al. Determinants of tumor response and survival with erlotinib in patients with non-small-cell lung cancer. J Clin Oncol 2004;22(16):3238-47
    • (2004) J Clin Oncol , vol.22 , Issue.16 , pp. 3238-3247
    • Perez-Soler, R.1    Chachoua, A.2    Hammond, L.A.3
  • 7
    • 84856058201 scopus 로고    scopus 로고
    • Pulmonary toxicities from targeted therapies: A review
    • Barber NA, Ganti AK. Pulmonary toxicities from targeted therapies: a review. Targeted oncology 2011;6(4):235-43
    • (2011) Targeted Oncology , vol.6 , Issue.4 , pp. 235-243
    • Barber, N.A.1    Ganti, A.K.2
  • 8
    • 84925548115 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: The PRISMA Statement
    • PRISMA Group
    • Moher D, Liberati A, Tetzlaff J, Altman DG; PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: The PRISMA Statement. J Clin Epidemiol 2009;62(10):1006-12
    • (2009) J Clin Epidemiol , vol.62 , Issue.10 , pp. 1006-1012
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4
  • 9
    • 84871473159 scopus 로고    scopus 로고
    • [Accessed on 20 November 2014]
    • National cancer institute. Common toxicity criteria. Available from: http://ctep.cancer. gov/protocoldevelopment/electronic-applications/docs/ctcaev3.pdf. [Accessed on 20 November 2014]
    • National Cancer Institute. Common Toxicity Criteria
  • 10
    • 75249084998 scopus 로고    scopus 로고
    • Randomized, placebo-controlled, phase II study of sequential erlotinib and chemotherapy as first-line treatment for advanced non-small-cell lung cancer
    • Mok TS, Wu YL, Yu CJ, et al. Randomized, placebo-controlled, phase II study of sequential erlotinib and chemotherapy as first-line treatment for advanced non-small-cell lung cancer. J Clin Oncol 2009;27(30):5080-7
    • (2009) J Clin Oncol , vol.27 , Issue.30 , pp. 5080-5087
    • Mok, T.S.1    Wu, Y.L.2    Yu, C.J.3
  • 11
    • 39749087795 scopus 로고    scopus 로고
    • Randomized phase II trial of erlotinib or standard chemotherapy in patients with advanced non-small-cell lung cancer and a performance status of 2
    • Lilenbaum R, Axelrod R, Thomas S, et al. Randomized phase II trial of erlotinib or standard chemotherapy in patients with advanced non-small-cell lung cancer and a performance status of 2. J Clin Oncol 2008; 26(6):863-9
    • (2008) J Clin Oncol , vol.26 , Issue.6 , pp. 863-869
    • Lilenbaum, R.1    Axelrod, R.2    Thomas, S.3
  • 12
    • 34248140107 scopus 로고    scopus 로고
    • Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non-small-cell lung cancer: The Tarceva lung cancer investigation Trial
    • Gatzemeier U, Pluzanska A, Szczesna A, et al. Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non-small-cell lung cancer: the Tarceva lung cancer investigation Trial. J Clin Oncol 2007;25(12):1545-52
    • (2007) J Clin Oncol , vol.25 , Issue.12 , pp. 1545-1552
    • Gatzemeier, U.1    Pluzanska, A.2    Szczesna, A.3
  • 13
    • 66249097440 scopus 로고    scopus 로고
    • A prospective pharmacogenomic (PG), pharmacodynamic (PD), and pharmacokinetic (PK) study of determinants of erlotinib toxicity
    • Rudin CM, Desai AA, Janisch L, et al. A prospective pharmacogenomic (PG), pharmacodynamic (PD), and pharmacokinetic (PK) study of determinants of erlotinib toxicity. J Clin Oncol 2006;24:3080
    • (2006) J Clin Oncol , vol.24 , pp. 3080
    • Rudin, C.M.1    Desai, A.A.2    Janisch, L.3
  • 14
    • 84925683938 scopus 로고    scopus 로고
    • [Last accessed on 29 August 2014]
    • TARCEVA. Available from: www.gene.com/download/pdf/tarceva-prescribing.pdf [Last accessed on 29 August 2014]
    • TARCEVA
  • 15
    • 84872099847 scopus 로고    scopus 로고
    • [Last accessed on 29 August 2014]
    • PRODUCT MONOGRAPH. Available from: http://hemonc.org/docs/packageinsert/gefitinib.pdf [Last accessed on 29 August 2014]
    • Product Monograph
  • 16
    • 83555166254 scopus 로고    scopus 로고
    • Randomized phase II study of gefitinib versus erlotinib in patients with advanced non-small cell lung cancer who failed previous chemotherapy
    • Kim ST, Uhm JE, Lee J, et al. Randomized phase II study of gefitinib versus erlotinib in patients with advanced non-small cell lung cancer who failed previous chemotherapy. Lung Cancer 2012;75(1):82-8
    • (2012) Lung Cancer , vol.75 , Issue.1 , pp. 82-88
    • Kim, S.T.1    Uhm, J.E.2    Lee, J.3
  • 17
    • 84862785051 scopus 로고    scopus 로고
    • Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): A phase 2b/3 randomised trial
    • Miller VA, Hirsh V, Cadranel J, et al. Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): a phase 2b/3 randomised trial. Lancet Oncol 2012;13(5):528-38
    • (2012) Lancet Oncol , vol.13 , Issue.5 , pp. 528-538
    • Miller, V.A.1    Hirsh, V.2    Cadranel, J.3
  • 18
    • 84885575248 scopus 로고    scopus 로고
    • Risk of oral and gastrointestinal mucosal injury among patients receiving selected targeted agents: A meta-analysis
    • Elting LS, Chang YC, Parelkar P, et al. Risk of oral and gastrointestinal mucosal injury among patients receiving selected targeted agents: a meta-analysis. Support Care Cancer 2013;21(11):3243-54
    • (2013) Support Care Cancer , vol.21 , Issue.11 , pp. 3243-3254
    • Elting, L.S.1    Chang, Y.C.2    Parelkar, P.3
  • 19
    • 84891656497 scopus 로고    scopus 로고
    • ATLAS: Randomized, double-blind, placebo-controlled, phase IIIB trial comparing bevacizumab therapy with or without erlotinib, after completion of chemotherapy, with bevacuzimab for first-line treatment of advanced non-smallcell-lung cancer
    • Johnson BE, Kabbinavar F, Fehrenbacher L, et al. ATLAS: randomized, double-blind, placebo-controlled, phase IIIB trial comparing bevacizumab therapy with or without erlotinib, after completion of chemotherapy, with bevacuzimab for first-line treatment of advanced non-smallcell-lung cancer. J Clin Oncol 2013;31: 3926-34
    • (2013) J Clin Oncol , vol.31 , pp. 3926-3934
    • Johnson, B.E.1    Kabbinavar, F.2    Fehrenbacher, L.3
  • 20
    • 84884906715 scopus 로고    scopus 로고
    • Three-arm randomised controlled phase 2 study comparing pemetrexed and erlotinib to either pemetrexed or erlotinib alone as second-line treatment for never-smokers with non-squamous non-small cell lung cancer
    • Lee DH, Lee JS, Kim SW, et al. Three-arm randomised controlled phase 2 study comparing pemetrexed and erlotinib to either pemetrexed or erlotinib alone as second-line treatment for never-smokers with non-squamous non-small cell lung cancer. Eur J Cancer 2013;49(15):3111-21
    • (2013) Eur J Cancer , vol.49 , Issue.15 , pp. 3111-3121
    • Lee, D.H.1    Lee, J.S.2    Kim, S.W.3
  • 21
    • 84883055532 scopus 로고    scopus 로고
    • Erlotinib versus docetaxel as second-line treatment of patients with advanced non-small-cell lung cancer and wild-type EGFR tumours (TAILOR): A randomised controlled trial
    • Garassino MC, Martelli O, Broggini M, et al. Erlotinib versus docetaxel as second-line treatment of patients with advanced non-small-cell lung cancer and wild-type EGFR tumours (TAILOR): a randomised controlled trial. Lancet Oncol 2013;14(10):981-8
    • (2013) Lancet Oncol , vol.14 , Issue.10 , pp. 981-988
    • Garassino, M.C.1    Martelli, O.2    Broggini, M.3
  • 22
    • 84879784343 scopus 로고    scopus 로고
    • Intercalated combination of chemotherapy and erlotinib for patients with advanced stage non-small-cell lung cancer (FASTACT-2): A randomised, double-blind trial
    • Wu YL, Lee JS, Thongprasert S, et al. Intercalated combination of chemotherapy and erlotinib for patients with advanced stage non-small-cell lung cancer (FASTACT-2): a randomised, double-blind trial. Lancet Oncol 2013;14(8):777-86
    • (2013) Lancet Oncol , vol.14 , Issue.8 , pp. 777-786
    • Wu, Y.L.1    Lee, J.S.2    Thongprasert, S.3
  • 23
    • 84880570204 scopus 로고    scopus 로고
    • Pemetrexed versus erlotinib in pretreated patients with advanced non-small cell lung cancer: A Hellenic Oncology Research Group (HORG) randomized phase 3 study
    • Karampeazis A, Voutsina A, Souglakos J, et al. Pemetrexed versus erlotinib in pretreated patients with advanced non-small cell lung cancer: a Hellenic Oncology Research Group (HORG) randomized phase 3 study. Cancer 2013;119(15): 2754-64
    • (2013) Cancer , vol.119 , Issue.15 , pp. 2754-2764
    • Karampeazis, A.1    Voutsina, A.2    Souglakos, J.3
  • 24
    • 84868192444 scopus 로고    scopus 로고
    • First-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy (TOPICAL): A double-blind, placebo-controlled, phase 3 trial
    • Lee SM, Khan I, Upadhyay S, et al. First-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy (TOPICAL): a double-blind, placebo-controlled, phase 3 trial. Lancet Oncol 2012;13:1161-70
    • (2012) Lancet Oncol , vol.13 , pp. 1161-1170
    • Lee, S.M.1    Khan, I.2    Upadhyay, S.3
  • 25
    • 84867059528 scopus 로고    scopus 로고
    • Randomized, Phase III study of gemcitabine or erlotinib maintenance therapy versus observation, with predefined second-line treatment, after cisplatin-gemcitabine induction chemotherapy in advanced non-small-cell lung cancer
    • Perol M, Chouaid C, Perol D, et al. Randomized, Phase III study of gemcitabine or erlotinib maintenance therapy versus observation, with predefined second-line treatment, after cisplatin-gemcitabine induction chemotherapy in advanced non-small-cell lung cancer. J Clin Oncol 2012;30:3516-24
    • (2012) J Clin Oncol , vol.30 , pp. 3516-3524
    • Perol, M.1    Chouaid, C.2    Perol, D.3
  • 26
    • 84865334851 scopus 로고    scopus 로고
    • A multi-centre randomized, open-label phase II trial of continuous erlotinib plus gemcitabine or gemcitabine as first-line therapy in ECOG PS2 patients with advanced non-small cell lung cancer
    • Michael M, Pavlakis N, Clingan P, et al. A multi-centre randomized, open-label phase II trial of continuous erlotinib plus gemcitabine or gemcitabine as first-line therapy in ECOG PS2 patients with advanced non-small cell lung cancer. Oncol Rep 2012;28(3):763-7
    • (2012) Oncol Rep , vol.28 , Issue.3 , pp. 763-767
    • Michael, M.1    Pavlakis, N.2    Clingan, P.3
  • 27
    • 84857502654 scopus 로고    scopus 로고
    • Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): A multicentre, open-label, randomised phase 3 trial
    • Rosell R, Carcereny E, Gervais R, et al. Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial. Lancet Oncol 2012;13(3): 239-46
    • (2012) Lancet Oncol , vol.13 , Issue.3 , pp. 239-246
    • Rosell, R.1    Carcereny, E.2    Gervais, R.3
  • 28
    • 84857501696 scopus 로고    scopus 로고
    • Efficacy and safety of erlotinib versus chemotherapy in second-line treatment of patients with advanced, non-small-cell lung cancer with poor prognosis (TITAN): A randomized multicentre, open-label, phase 3 study
    • Ciuleanu T, Stelmakh L, Cicenas S, et al. Efficacy and safety of erlotinib versus chemotherapy in second-line treatment of patients with advanced, non-small-cell lung cancer with poor prognosis (TITAN): a randomized multicentre, open-label, phase 3 study. Lancet Oncol 2012;13(3): 300-8
    • (2012) Lancet Oncol , vol.13 , Issue.3 , pp. 300-308
    • Ciuleanu, T.1    Stelmakh, L.2    Cicenas, S.3
  • 29
    • 84858339030 scopus 로고    scopus 로고
    • Phase II randomized trial of erlotinib or vinorelbine in chemonaive, advanced, non-small cell lung cancer patients aged 70 years or older
    • Chen YM, Tsai CM, Fan WC, et al. Phase II randomized trial of erlotinib or vinorelbine in chemonaive, advanced, non-small cell lung cancer patients aged 70 years or older. J Thorac Oncol 2012; 7(2):412-18
    • (2012) J Thorac Oncol , vol.7 , Issue.2 , pp. 412-418
    • Chen, Y.M.1    Tsai, C.M.2    Fan, W.C.3
  • 30
    • 79960889662 scopus 로고    scopus 로고
    • Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): A multicentre, open-label, randomised, phase 3 study
    • Zhou C, Wu YL, Chen G, et al. Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study. Lancet Oncol 2011;12(8):735-42
    • (2011) Lancet Oncol , vol.12 , Issue.8 , pp. 735-742
    • Zhou, C.1    Wu, Y.L.2    Chen, G.3
  • 31
    • 80052273497 scopus 로고    scopus 로고
    • A randomized phase II trial of first-line treatment with gemcitabine, erlotinib, or gemcitabine and erlotinib in elderly patients (age ≥70 years) with stage IIIB/IV non-small cell lung cancer
    • Stinchcombe TE, Peterman AH, Lee CB, et al. A randomized phase II trial of first-line treatment with gemcitabine, erlotinib, or gemcitabine and erlotinib in elderly patients (age ≥70 years) with stage IIIB/IV non-small cell lung cancer. J ThoracOncol 2011;6(9):1569-77
    • (2011) J ThoracOncol , vol.6 , Issue.9 , pp. 1569-1577
    • Stinchcombe, T.E.1    Peterman, A.H.2    Lee, C.B.3
  • 32
    • 77953541527 scopus 로고    scopus 로고
    • Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: A multicentre, randomised, placebo-controlled phase 3 study
    • Cappuzzo F, Ciuleanu T, Stelmakh L, et al. Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study. Lancet Oncol 2010;11(6):521-9
    • (2010) Lancet Oncol , vol.11 , Issue.6 , pp. 521-529
    • Cappuzzo, F.1    Ciuleanu, T.2    Stelmakh, L.3
  • 33
    • 24944440830 scopus 로고    scopus 로고
    • TRIBUTE: A phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer
    • Herbst RS, Prager D, Hermann R, et al. TRIBUTE: a phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer. J Clin Oncol 2005;23(25):5892-9
    • (2005) J Clin Oncol , vol.23 , Issue.25 , pp. 5892-5899
    • Herbst, R.S.1    Prager, D.2    Hermann, R.3
  • 34
    • 22044445517 scopus 로고    scopus 로고
    • Erlotinib in previously treated non-small-cell lung cancer
    • Shepherd FA, Rodrigues Pereira J, Ciuleanu T, et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 2005;353(2):123-32
    • (2005) N Engl J Med , vol.353 , Issue.2 , pp. 123-132
    • Shepherd, F.A.1    Rodrigues Pereira, J.2    Ciuleanu, T.3


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