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Volumn 34, Issue 2, 2015, Pages e23-e31

Prevalence of lipodystrophy and metabolic abnormalities in HIV-infected African children after 3 years on first-line antiretroviral therapy

Author keywords

Africa; Antiretroviral therapy; Children; HIV; Lipids; Lipodystrophy

Indexed keywords

ABACAVIR; ALBUMIN; EFAVIRENZ; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LAMIVUDINE; LOPINAVIR PLUS RITONAVIR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; NEVIRAPINE; STAVUDINE; TENOFOVIR; TRIACYLGLYCEROL; ZIDOVUDINE; ANTIRETROVIRUS AGENT; LIPID; DIDANOSINE; HIGH DENSITY LIPOPROTEIN;

EID: 84925640301     PISSN: 13057707     EISSN: 13057693     Source Type: Journal    
DOI: 10.1097/INF.0000000000000491     Document Type: Article
Times cited : (19)

References (51)
  • 1
    • 84859374751 scopus 로고    scopus 로고
    • Body fat abnormality in HIV-infected children and adolescents living in Europe: Prevalence and risk factors
    • Alam N, Cortina-Borja M, Goetghebuer T, et al; European Paediatric HIV and Lipodystrophy Study Group in EuroCoord. Body fat abnormality in HIV-infected children and adolescents living in Europe: prevalence and risk factors. J Acquir Immune Defic Syndr. 2012;59:314-324.
    • (2012) J Acquir Immune Defic Syndr , vol.59 , pp. 314-324
    • Alam, N.1    Cortina-Borja, M.2    Goetghebuer, T.3
  • 2
    • 0035999346 scopus 로고    scopus 로고
    • Lipodystrophy syndrome in human immunodeficiency virus-infected children
    • Amaya RA, Kozinetz CA, McMeans A, et al. Lipodystrophy syndrome in human immunodeficiency virus-infected children. Pediatr Infect Dis J. 2002;21:405-410.
    • (2002) Pediatr Infect Dis J , vol.21 , pp. 405-410
    • Amaya, R.A.1    Kozinetz, C.A.2    McMeans, A.3
  • 3
    • 68649125624 scopus 로고    scopus 로고
    • Longitudinal changes in regional fat content in HIV-infected children and adolescents
    • Arpadi SM, Bethel J, Horlick M, et al. Longitudinal changes in regional fat content in HIV-infected children and adolescents. AIDS. 2009;23:1501-1509.
    • (2009) AIDS , vol.23 , pp. 1501-1509
    • Arpadi, S.M.1    Bethel, J.2    Horlick, M.3
  • 4
    • 38049009326 scopus 로고    scopus 로고
    • Lipodystrophy and metabolic changes in HIV-infected children on non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy
    • Aurpibul L, Puthanakit T, Lee B, et al. Lipodystrophy and metabolic changes in HIV-infected children on non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy. Antivir Ther. 2007;12:1247-1254.
    • (2007) Antivir Ther , vol.12 , pp. 1247-1254
    • Aurpibul, L.1    Puthanakit, T.2    Lee, B.3
  • 5
    • 84861794647 scopus 로고    scopus 로고
    • Characteristics of human immunodeficiency virus-1 infected children receiving highly active antiretroviral therapy: A cross-sectional study
    • Badillo K, Prieto L, Toledano M, et al. Characteristics of human immunodeficiency virus-1 infected children receiving highly active antiretroviral therapy: a cross-sectional study. An Pediatr (Barc) 2012;76:317-323.
    • (2012) An Pediatr (Barc) , vol.76 , pp. 317-323
    • Badillo, K.1    Prieto, L.2    Toledano, M.3
  • 6
    • 25844487693 scopus 로고    scopus 로고
    • Longitudinal evaluation and risk factors of lipodystrophy and associated metabolic changes in HIV-infected children
    • Beregszaszi M, Dollfus C, Levine M, et al. Longitudinal evaluation and risk factors of lipodystrophy and associated metabolic changes in HIV-infected children. J Acquir Immune Defic Syndr. 2005;40:161-168.
    • (2005) J Acquir Immune Defic Syndr , vol.40 , pp. 161-168
    • Beregszaszi, M.1    Dollfus, C.2    Levine, M.3
  • 7
    • 33845428577 scopus 로고    scopus 로고
    • Prevalence of lipodystrophy in HIV-infected children: A cross-sectional study
    • Ene L, Goetghebuer T, Hainaut M, et al. Prevalence of lipodystrophy in HIV-infected children: a cross-sectional study. Eur J Pediatr. 2007;166:13-21.
    • (2007) Eur J Pediatr , vol.166 , pp. 13-21
    • Ene, L.1    Goetghebuer, T.2    Hainaut, M.3
  • 8
    • 3142707107 scopus 로고    scopus 로고
    • Antiretroviral therapy, fat redistribution and hyperlipidaemia in HIV-infected children in Europe
    • European Paediatric Lipodystrophy G. Antiretroviral therapy, fat redistribution and hyperlipidaemia in HIV-infected children in Europe. AIDS. 2004,18:1443-1451.
    • (2004) AIDS , vol.18 , pp. 1443-1451
  • 9
    • 84869885561 scopus 로고    scopus 로고
    • High prevalence of lipoatrophy in pre-pubertal South African children on antiretroviral therapy: A cross-sectional study
    • Innes S, Cotton MF, Haubrich R, et al. High prevalence of lipoatrophy in pre-pubertal South African children on antiretroviral therapy: a cross-sectional study. BMC Pediatr. 2012;12:183.
    • (2012) BMC Pediatr , vol.12 , pp. 183
    • Innes, S.1    Cotton, M.F.2    Haubrich, R.3
  • 10
    • 0033783232 scopus 로고    scopus 로고
    • Clinical and metabolic presentation of the lipodystrophic syndrome in HIV-infected children
    • Jaquet D, Lévine M, Ortega-Rodriguez E, et al. Clinical and metabolic presentation of the lipodystrophic syndrome in HIV-infected children. AIDS. 2000;14:2123-2128.
    • (2000) AIDS , vol.14 , pp. 2123-2128
    • Jaquet, D.1    Lévine, M.2    Ortega-Rodriguez, E.3
  • 11
    • 67649099433 scopus 로고    scopus 로고
    • The prognosis of pediatric AIDS in serbia
    • Jevtović D, Salemović D, Ranin J, et al. The prognosis of pediatric AIDS in serbia. Curr HIV Res. 2009;7:287-292.
    • (2009) Curr HIV Res , vol.7 , pp. 287-292
    • Jevtović, D.1    Salemović, D.2    Ranin, J.3
  • 12
    • 83455200007 scopus 로고    scopus 로고
    • High prevalence of lipid abnormalities among antiretroviral-naive HIV-infected Asian children with mild-to-moderate immunosuppression
    • Kanjanavanit S, Puthanakit T, Vibol U, et al; PREDICT study group. High prevalence of lipid abnormalities among antiretroviral-naive HIV-infected Asian children with mild-to-moderate immunosuppression. Antivir Ther. 2011;16:1351-1355.
    • (2011) Antivir Ther , vol.16 , pp. 1351-1355
    • Kanjanavanit, S.1    Puthanakit, T.2    Vibol, U.3
  • 13
    • 84871792120 scopus 로고    scopus 로고
    • Prevalence of lipodystrophy in HIV-infected children in Tanzania on highly active antiretroviral therapy
    • Kinabo GD, Sprengers M, Msuya LJ, et al. Prevalence of lipodystrophy in HIV-infected children in Tanzania on highly active antiretroviral therapy. Pediatr Infect Dis J. 2013;32:39-44.
    • (2013) Pediatr Infect Dis J , vol.32 , pp. 39-44
    • Kinabo, G.D.1    Sprengers, M.2    Msuya, L.J.3
  • 14
    • 84867469771 scopus 로고    scopus 로고
    • Lipodystrophy among HIV-infected children and adolescents on highly active antiretroviral therapy in Uganda: A cross sectional study
    • Piloya T, Bakeera-Kitaka S, Kekitiinwa A, et al. Lipodystrophy among HIV-infected children and adolescents on highly active antiretroviral therapy in Uganda: a cross sectional study. J Int AIDS Soc. 2012;15:17427.
    • (2012) J Int AIDS Soc , vol.15 , pp. 17427
    • Piloya, T.1    Bakeera-Kitaka, S.2    Kekitiinwa, A.3
  • 15
    • 60649118782 scopus 로고    scopus 로고
    • Lipodystrophic syndrome in children and adolescents infected with the human immunodeficiency virus
    • Alves C, Oliveira AC, Brites C. Lipodystrophic syndrome in children and adolescents infected with the human immunodeficiency virus. Braz J Infect Dis. 2008;12:342-348.
    • (2008) Braz J Infect Dis , vol.12 , pp. 342-348
    • Alves, C.1    Oliveira, A.C.2    Brites, C.3
  • 16
    • 0035330601 scopus 로고    scopus 로고
    • Lipodystrophy in HIV-infected children is associated with high viral load and low CD4+-lymphocyte count and CD4+-lymphocyte percentage at baseline and use of protease inhibitors and stavudine
    • Arpadi SM, Cuff PA, Horlick M, et al. Lipodystrophy in HIV-infected children is associated with high viral load and low CD4+-lymphocyte count and CD4+-lymphocyte percentage at baseline and use of protease inhibitors and stavudine. J Acquir Immune Defic Syndr. 2001;27:30-34.
    • (2001) J Acquir Immune Defic Syndr , vol.27 , pp. 30-34
    • Arpadi, S.M.1    Cuff, P.A.2    Horlick, M.3
  • 17
    • 33646811532 scopus 로고    scopus 로고
    • Dyslipidemia among perinatally HIV-infected children enrolled in the PACTS-HOPE cohort, 1999-2004: A longitudinal analysis
    • Carter RJ, Wiener J, Abrams EJ, et al; Perinatal AIDS Collaborative Transmission Study-HIV Follow-up after Perinatal Exposure (PACTS-HOPE) Group. Dyslipidemia among perinatally HIV-infected children enrolled in the PACTS-HOPE cohort, 1999-2004: a longitudinal analysis. J Acquir Immune Defic Syndr. 2006;41:453-460.
    • (2006) J Acquir Immune Defic Syndr , vol.41 , pp. 453-460
    • Carter, R.J.1    Wiener, J.2    Abrams, E.J.3
  • 18
    • 77955175937 scopus 로고    scopus 로고
    • Association between lipodystrophy and leptin in human immunodeficiency virus-1-infected children receiving lopinavir/ritonavir-based therapy
    • Resino S, Palladino C, Lorente R, et al Spanish Group of Pediatric HIV Infection. Association between lipodystrophy and leptin in human immunodeficiency virus-1-infected children receiving lopinavir/ritonavir-based therapy. Pediatr Infect Dis J. 2010;29:774-777.
    • (2010) Pediatr Infect Dis J , vol.29 , pp. 774-777
    • Resino, S.1    Palladino, C.2    Lorente, R.3
  • 20
    • 84876187057 scopus 로고    scopus 로고
    • Metabolic abnormalities and body composition of HIV-infected children on Lopinavir or Nevirapine-based antiretroviral therapy
    • Arpadi S, Shiau S, Strehlau R, et al. Metabolic abnormalities and body composition of HIV-infected children on Lopinavir or Nevirapine-based antiretroviral therapy. Arch Dis Child. 2013;98:258-264.
    • (2013) Arch Dis Child , vol.98 , pp. 258-264
    • Arpadi, S.1    Shiau, S.2    Strehlau, R.3
  • 21
    • 84902673704 scopus 로고    scopus 로고
    • Anthropometric measurements and lipid profiles to detect early lipodystrophy in antiretroviral therapy experienced HIV-infected children in the CHAPAS-3-trial
    • Musiime V, Cook A, Kayiwa J, et al. Anthropometric measurements and lipid profiles to detect early lipodystrophy in antiretroviral therapy experienced HIV-infected children in the CHAPAS-3-trial. Antivir Ther. 2014;19:269-276.
    • (2014) Antivir Ther , vol.19 , pp. 269-276
    • Musiime, V.1    Cook, A.2    Kayiwa, J.3
  • 25
    • 84882369956 scopus 로고    scopus 로고
    • Tenofovir-related Fanconi's syndrome and osteomalacia in a teenager with HIV
    • published online July 9
    • Lucey JM, Hsu P, Ziegler JB. Tenofovir-related Fanconi's syndrome and osteomalacia in a teenager with HIV. BMJ Case Rep. [published online July 9, 2013]. doi: 10.1136/bcr-2013-008674.
    • (2013) BMJ Case Rep
    • Lucey, J.M.1    Hsu, P.2    Ziegler, J.B.3
  • 26
    • 85029548837 scopus 로고    scopus 로고
    • Tenofovir treatment duration predicts proteinuria in a multiethnic United States Cohort of children and adolescents with perinatal HIV-1 infection
    • Purswani M, Patel K, Kopp JB, et al Pediatric HIVAIDS Cohort Study. Tenofovir treatment duration predicts proteinuria in a multiethnic United States Cohort of children and adolescents with perinatal HIV-1 infection. Pediatr Infect Dis J. 2013;32:495-500.
    • (2013) Pediatr Infect Dis J , vol.32 , pp. 495-500
    • Purswani, M.1    Patel, K.2    Kopp, J.B.3
  • 28
    • 84878388296 scopus 로고    scopus 로고
    • Systematic review of antiretroviral-associated lipodystrophy: Lipoatrophy, but not central fat gain, is an antiretroviral adverse drug reaction
    • de Waal R, Cohen K, Maartens G. Systematic review of antiretroviral-associated lipodystrophy: lipoatrophy, but not central fat gain, is an antiretroviral adverse drug reaction. PLoS One. 2013;8:e63623.
    • (2013) PLoS One , vol.8 , pp. e63623
    • De Waal, R.1    Cohen, K.2    Maartens, G.3
  • 29
    • 84879117069 scopus 로고    scopus 로고
    • Adverse events associated with nevirapine and efavirenz-based first-line antiretroviral therapy: A systematic review and meta-analysis
    • Shubber Z, Calmy A, Andrieux-Meyer I, et al. Adverse events associated with nevirapine and efavirenz-based first-line antiretroviral therapy: a systematic review and meta-analysis. AIDS. 2013;27:1403-1412.
    • (2013) AIDS , vol.27 , pp. 1403-1412
    • Shubber, Z.1    Calmy, A.2    Andrieux-Meyer, I.3
  • 30
    • 84859739655 scopus 로고    scopus 로고
    • Safety and tolerability of antiretroviral therapy among HIV-infected children and adolescents in Uganda
    • Tukei VJ, Asiimwe A, Maganda A, et al. Safety and tolerability of antiretroviral therapy among HIV-infected children and adolescents in Uganda. J Acquir Immune Defic Syndr. 2012;59:274-280.
    • (2012) J Acquir Immune Defic Syndr , vol.59 , pp. 274-280
    • Tukei, V.J.1    Asiimwe, A.2    Maganda, A.3
  • 31
    • 84876280807 scopus 로고    scopus 로고
    • Routine versus clinically driven laboratory monitoring and first-line antiretroviral therapy strategies in African children with HIV (ARROW): A 5-year open-label randomised factorial trial
    • Arrow Trial Team. Routine versus clinically driven laboratory monitoring and first-line antiretroviral therapy strategies in African children with HIV (ARROW): a 5-year open-label randomised factorial trial. Lancet 2013;381:1391-1403.
    • (2013) Lancet , vol.381 , pp. 1391-1403
  • 34
    • 17444421898 scopus 로고    scopus 로고
    • Are age references for waist circumference, hip circumference and waist-hip ratio in Dutch children useful in clinical practice?
    • Fredriks AM, van Buuren S, Fekkes M, et al. Are age references for waist circumference, hip circumference and waist-hip ratio in Dutch children useful in clinical practice? Eur J Pediatr. 2005;164:216-222.
    • (2005) Eur J Pediatr , vol.164 , pp. 216-222
    • Fredriks, A.M.1    Van Buuren, S.2    Fekkes, M.3
  • 36
    • 0028072386 scopus 로고
    • Age-related reference ranges: Significance tests for models and confidence intervals for centiles
    • Wade AM, Ades AE. Age-related reference ranges: significance tests for models and confidence intervals for centiles. Stat Med. 1994;13:2359-2367.
    • (1994) Stat Med , vol.13 , pp. 2359-2367
    • Wade, A.M.1    Ades, A.E.2
  • 37
    • 34548307594 scopus 로고    scopus 로고
    • Available at: Accessed March 10, 2014
    • National Institute for Allergy and Infectious Disease (NIAID). Division of AIDS Table for Grading the Severity of Adult and Pediatric Adverse Events. 2004. Available at: http://www.niaid.nih.gov/labsandresources/resources/daidsclinrsrch/documents/daidsaegradingtable.pdf. Accessed March 10, 2014.
    • (2004) Division of AIDS Table for Grading the Severity of Adult and Pediatric Adverse Events
  • 38
    • 84055213533 scopus 로고    scopus 로고
    • Expert Panel on integrated guidelines for cardiovascular health and risk reduction in children and adolescents: Summary report
    • Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents. Expert Panel on integrated guidelines for cardiovascular health and risk reduction in children and adolescents: summary report. Pediatrics 2011,128:S213-S256.
    • (2011) Pediatrics , vol.128 , pp. S213-S256
  • 39
    • 84858798561 scopus 로고    scopus 로고
    • Recovery from lipodystrophy in HIV-infected children after substitution of stavudine with zidovudine in a non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy
    • Aurpibul L, Puthanakit T, Taejaroenkul S, et al. Recovery from lipodystrophy in HIV-infected children after substitution of stavudine with zidovudine in a non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy. Pediatr Infect Dis J. 2012;31:384-388.
    • (2012) Pediatr Infect Dis J , vol.31 , pp. 384-388
    • Aurpibul, L.1    Puthanakit, T.2    Taejaroenkul, S.3
  • 40
    • 34247584016 scopus 로고    scopus 로고
    • Lamivudine/abacavir maintains virological superiority over zidovudine/lamivudine and zidovudine/abacavir beyond 5 years in children
    • Green H, Gibb DM, Walker AS, et al Paediatric European Network for the Treatment of AIDS (PENTA). Lamivudine/abacavir maintains virological superiority over zidovudine/lamivudine and zidovudine/abacavir beyond 5 years in children. AIDS. 2007;21:947-955.
    • (2007) AIDS , vol.21 , pp. 947-955
    • Paediatric European Network for the Treatment of AIDS (PENTA)1    Green, H.2    Gibb, D.M.3    Walker, A.S.4
  • 41
    • 0037006656 scopus 로고    scopus 로고
    • Comparison of dual nucleoside-analogue reverse-transcriptase inhibitor regimens with and without nelfinavir in children with HIV-1 who have not previously been treated: The PENTA 5 randomised trial
    • Paediatric European Network for Treatment of AIDS (PENTA). Comparison of dual nucleoside-analogue reverse-transcriptase inhibitor regimens with and without nelfinavir in children with HIV-1 who have not previously been treated: the PENTA 5 randomised trial. Lancet. 2002;359:733-740.
    • (2002) Lancet , vol.359 , pp. 733-740
    • Paediatric European Network for Treatment of AIDS (PENTA)1
  • 42
    • 84901508992 scopus 로고    scopus 로고
    • Virologic response in children treated with abacavir compared with stavudine-based antiretroviral treatment - A South African multi-cohort analysis
    • Technau KG, Schomaker M, Kuhn L, Moultrie H, Coovadia A, Eley B, et al. Virologic response in children treated with abacavir compared with stavudine-based antiretroviral treatment - a South African multi-cohort analysis. Pediatr Infect Dis J. 2014;33:617-622.
    • (2014) Pediatr Infect Dis J , vol.33 , pp. 617-622
    • Technau, K.G.1    Schomaker, M.2    Kuhn, L.3    Moultrie, H.4    Coovadia, A.5    Eley, B.6
  • 43
    • 77955950938 scopus 로고    scopus 로고
    • Stavudine or zidovudine in three-drug combination therapy for initial treatment of HIV infection in antiretroviral-naive individuals
    • Spaulding A, Rutherford GW, Siegfried N. Stavudine or zidovudine in three-drug combination therapy for initial treatment of HIV infection in antiretroviral-naive individuals. Cochrane Database Syst Rev 2010:CD008651.
    • (2010) Cochrane Database Syst Rev
    • Spaulding, A.1    Rutherford, G.W.2    Siegfried, N.3
  • 44
    • 84878316515 scopus 로고    scopus 로고
    • First-line antiretroviral therapy and changes in lipid levels over 3 years among HIV-infected adults in Tanzania
    • Liu E, Armstrong C, Spiegelman D, et al. First-line antiretroviral therapy and changes in lipid levels over 3 years among HIV-infected adults in Tanzania. Clin Infect Dis. 2013;56:1820-1828.
    • (2013) Clin Infect Dis , vol.56 , pp. 1820-1828
    • Liu, E.1    Armstrong, C.2    Spiegelman, D.3
  • 45
    • 50449085440 scopus 로고    scopus 로고
    • High ratio of triglycerides to HDL-cholesterol predicts extensive coronary disease
    • da Luz PL, Favarato D, Faria-Neto JR Jr, et al. High ratio of triglycerides to HDL-cholesterol predicts extensive coronary disease. Clinics (Sao Paulo). 2008;63:427-432.
    • (2008) Clinics (Sao Paulo) , vol.63 , pp. 427-432
    • Da Luz, P.L.1    Favarato, D.2    Faria-Neto, J.R.3
  • 46
    • 15744367156 scopus 로고    scopus 로고
    • Nevirapine and efavirenz elicit different changes in lipid profiles in antiretroviral-therapy-naive patients infected with HIV-1
    • van Leth F, Phanuphak P, Stroes E, et al. Nevirapine and efavirenz elicit different changes in lipid profiles in antiretroviral-therapy-naive patients infected with HIV-1. PLoS Med. 2004;1:e19.
    • (2004) PLoS Med , vol.1 , pp. e19
    • Van Leth, F.1    Phanuphak, P.2    Stroes, E.3
  • 47
    • 34447097101 scopus 로고    scopus 로고
    • Efavirenz to nevirapine switch in HIV-1-infected patients with dyslipidemia: A randomized, controlled study
    • Parienti JJ, Massari V, Rey D, et al; SIROCCO study team. Efavirenz to nevirapine switch in HIV-1-infected patients with dyslipidemia: a randomized, controlled study. Clin Infect Dis. 2007;45:263-266.
    • (2007) Clin Infect Dis , vol.45 , pp. 263-266
    • Parienti, J.J.1    Massari, V.2    Rey, D.3
  • 48
    • 84926031146 scopus 로고    scopus 로고
    • Available at: Accessed November 4, 2013
    • Federal Drug Authority. Sustiva (efavirenz) pediatric patients labeling update Available at: http://www.fda.gov/ForConsumers/ByAudience/ForPatientAdvocates/HIVandAIDSActivities/ucm350744.htm. Accessed November 4, 2013.
    • Sustiva (Efavirenz) Pediatric Patients Labeling Update
  • 49
    • 84877139214 scopus 로고    scopus 로고
    • Association between efavirenz-based compared with nevirapine-based antiretroviral regimens and virological failure in HIV-infected children
    • Lowenthal ED, Ellenberg JH, Machine E, et al. Association between efavirenz-based compared with nevirapine-based antiretroviral regimens and virological failure in HIV-infected children. JAMA. 2013;309:1803-1809.
    • (2013) JAMA , vol.309 , pp. 1803-1809
    • Lowenthal, E.D.1    Ellenberg, J.H.2    Machine, E.3
  • 51
    • 80051544789 scopus 로고    scopus 로고
    • Effect of specific ART drugs on lipid changes and the need for lipid management in children with HIV
    • Rhoads MP, Lanigan J, Smith CJ, et al. Effect of specific ART drugs on lipid changes and the need for lipid management in children with HIV. J Acquir Immune Defic Syndr. 2011;57:404-412.
    • (2011) J Acquir Immune Defic Syndr , vol.57 , pp. 404-412
    • Rhoads, M.P.1    Lanigan, J.2    Smith, C.J.3


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