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Volumn 6, Issue 8, 2015, Pages 5650-5665

Knockdown of GALNT1 suppresses malignant phenotype of hepatocellular carcinoma by suppressing EGFR signaling

Author keywords

Epidermal growth factor receptor; GalNAc transferase; GALNT1; O glycosylation; Receptor tyrosine kinase

Indexed keywords

EARLY ENDOSOME ANTIGEN 1; EPIDERMAL GROWTH FACTOR RECEPTOR; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MESSENGER RNA; N ACETYLGALACTOSAMINYLTRANSFERASE; N ACETYLGALACTOSAMINYLTRANSFERASE 1; UNCLASSIFIED DRUG; EGFR PROTEIN, HUMAN; POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE;

EID: 84925610442     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3117     Document Type: Article
Times cited : (40)

References (36)
  • 6
    • 40449113855 scopus 로고    scopus 로고
    • Epidermal growth factor receptor expression and gene copy number in conventional hepatocellular carcinoma
    • Buckley AF, Burgart LJ, Sahai V, Kakar S. Epidermal growth factor receptor expression and gene copy number in conventional hepatocellular carcinoma. American journal of clinical pathology. 2008; 129:245-251.
    • (2008) American journal of clinical pathology , vol.129 , pp. 245-251
    • Buckley, A.F.1    Burgart, L.J.2    Sahai, V.3    Kakar, S.4
  • 7
    • 84860365843 scopus 로고    scopus 로고
    • Control of mucin-type O-glycosylation: a classification of the polypeptide GalNAc-transferase gene family
    • Bennett EP, Mandel U, Clausen H, Gerken TA, Fritz TA, Tabak LA. Control of mucin-type O-glycosylation: a classification of the polypeptide GalNAc-transferase gene family. Glycobiology. 2012; 22:736-756.
    • (2012) Glycobiology , vol.22 , pp. 736-756
    • Bennett, E.P.1    Mandel, U.2    Clausen, H.3    Gerken, T.A.4    Fritz, T.A.5    Tabak, L.A.6
  • 8
    • 33845941133 scopus 로고    scopus 로고
    • Identification of common and unique peptide substrate preferences for the UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferases T1 and T2 derived from oriented random peptide substrates
    • Gerken TA, Raman J, Fritz TA, Jamison O. Identification of common and unique peptide substrate preferences for the UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferases T1 and T2 derived from oriented random peptide substrates. The Journal of biological chemistry. 2006; 281:32403-32416.
    • (2006) The Journal of biological chemistry , vol.281 , pp. 32403-32416
    • Gerken, T.A.1    Raman, J.2    Fritz, T.A.3    Jamison, O.4
  • 9
    • 0042317189 scopus 로고    scopus 로고
    • Functional characterization and expression analysis of members of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family from Drosophila melanogaster
    • Ten Hagen KG, Tran DT, Gerken TA, Stein DS, Zhang Z. Functional characterization and expression analysis of members of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family from Drosophila melanogaster. The Journal of biological chemistry. 2003; 278:35039-35048.
    • (2003) The Journal of biological chemistry , vol.278 , pp. 35039-35048
    • Ten Hagen, K.G.1    Tran, D.T.2    Gerken, T.A.3    Stein, D.S.4    Zhang, Z.5
  • 10
    • 33744799438 scopus 로고    scopus 로고
    • Mucin-type O-glycans in human colon and breast cancer: glycodynamics and functions
    • Brockhausen I. Mucin-type O-glycans in human colon and breast cancer: glycodynamics and functions. EMBO reports. 2006; 7:599-604.
    • (2006) EMBO reports , vol.7 , pp. 599-604
    • Brockhausen, I.1
  • 14
    • 84896720044 scopus 로고    scopus 로고
    • Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation
    • Wang ZQ, Bachvarova M, Morin C, Plante M, Gregoire J, Renaud MC, Sebastianelli A, Bachvarov D. Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation. Oncotarget. 2014; 5:544-560.
    • (2014) Oncotarget , vol.5 , pp. 544-560
    • Wang, Z.Q.1    Bachvarova, M.2    Morin, C.3    Plante, M.4    Gregoire, J.5    Renaud, M.C.6    Sebastianelli, A.7    Bachvarov, D.8
  • 15
    • 84879677603 scopus 로고    scopus 로고
    • The mucin-type glycosylating enzyme polypeptide N-acetylgalactosaminyltransferase 14 promotes the migration of ovarian cancer by modifying mucin 13
    • Wang R, Yu C, Zhao D, Wu M, Yang Z. The mucin-type glycosylating enzyme polypeptide N-acetylgalactosaminyltransferase 14 promotes the migration of ovarian cancer by modifying mucin 13. Oncology reports. 2013; 30:667-676.
    • (2013) Oncology reports , vol.30 , pp. 667-676
    • Wang, R.1    Yu, C.2    Zhao, D.3    Wu, M.4    Yang, Z.5
  • 16
    • 84859996620 scopus 로고    scopus 로고
    • MicroRNA-214 suppresses growth and invasiveness of cervical cancer cells by targeting UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylga lactosaminyltransferase 7
    • Peng RQ, Wan HY, Li HF, Liu M, Li X, Tang H. MicroRNA-214 suppresses growth and invasiveness of cervical cancer cells by targeting UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylga lactosaminyltransferase 7. The Journal of biological chemistry. 2012; 287:14301-14309.
    • (2012) The Journal of biological chemistry , vol.287 , pp. 14301-14309
    • Peng, R.Q.1    Wan, H.Y.2    Li, H.F.3    Liu, M.4    Li, X.5    Tang, H.6
  • 20
    • 84879607251 scopus 로고    scopus 로고
    • MicroRNA-140-5p suppresses tumor growth and metastasis by targeting transforming growth factor beta receptor 1 and fibroblast growth factor 9 in hepatocellular carcinoma
    • Yang H, Fang F, Chang R, Yang L. MicroRNA-140-5p suppresses tumor growth and metastasis by targeting transforming growth factor beta receptor 1 and fibroblast growth factor 9 in hepatocellular carcinoma. Hepatology (Baltimore, Md). 2013; 58:205-217.
    • (2013) Hepatology (Baltimore, Md) , vol.58 , pp. 205-217
    • Yang, H.1    Fang, F.2    Chang, R.3    Yang, L.4
  • 22
    • 84919479359 scopus 로고    scopus 로고
    • Autocrine vascular endothelial growth factor signaling promotes cell proliferation and modulates sorafenib treatment efficacy in hepatocellular carcinoma
    • Peng S, Wang Y, Peng H, Chen D, Shen S, Peng B, Chen M, Lencioni R, Kuang M. Autocrine vascular endothelial growth factor signaling promotes cell proliferation and modulates sorafenib treatment efficacy in hepatocellular carcinoma. Hepatology (Baltimore, Md). 2014; 60:1264-1277.
    • (2014) Hepatology (Baltimore, Md) , vol.60 , pp. 1264-1277
    • Peng, S.1    Wang, Y.2    Peng, H.3    Chen, D.4    Shen, S.5    Peng, B.6    Chen, M.7    Lencioni, R.8    Kuang, M.9
  • 25
    • 84893669713 scopus 로고    scopus 로고
    • The role of EGF-EGFR signalling pathway in hepatocellular carcinoma inflammatory microenvironment
    • Huang P, Xu X, Wang L, Zhu B, Wang X, Xia J. The role of EGF-EGFR signalling pathway in hepatocellular carcinoma inflammatory microenvironment. Journal of cellular and molecular medicine. 2014; 18:218-230.
    • (2014) Journal of cellular and molecular medicine , vol.18 , pp. 218-230
    • Huang, P.1    Xu, X.2    Wang, L.3    Zhu, B.4    Wang, X.5    Xia, J.6
  • 26
    • 13444263549 scopus 로고    scopus 로고
    • Clathrin-and non-clathrin-mediated endocytic regulation of cell signalling
    • Le Roy C, Wrana JL. Clathrin-and non-clathrin-mediated endocytic regulation of cell signalling. Nature reviews Molecular cell biology. 2005; 6:112-126.
    • (2005) Nature reviews Molecular cell biology , vol.6 , pp. 112-126
    • Le Roy, C.1    Wrana, J.L.2
  • 27
    • 84887497121 scopus 로고    scopus 로고
    • The quest to overcome resistance to EGFR-targeted therapies in cancer
    • Chong CR, Janne PA. The quest to overcome resistance to EGFR-targeted therapies in cancer. Nature medicine. 2013; 19:1389-1400.
    • (2013) Nature medicine , vol.19 , pp. 1389-1400
    • Chong, C.R.1    Janne, P.A.2
  • 28
    • 84873668603 scopus 로고    scopus 로고
    • Investigational therapies targeting the ErbB (EGFR, HER2, HER3, HER4) ErbB family in GI cancers
    • Desai MD, Saroya BS, Lockhart AC. Investigational therapies targeting the ErbB (EGFR, HER2, HER3, HER4) ErbB family in GI cancers. Expert opinion on investigational drugs. 2013; 22:341-356.
    • (2013) Expert opinion on investigational drugs , vol.22 , pp. 341-356
    • Desai, M.D.1    Saroya, B.S.2    Lockhart, A.C.3
  • 32
    • 0344897638 scopus 로고    scopus 로고
    • Tetraspanin CD82 regulates compartmentalisation and ligand-induced dimerization of EGFR
    • Odintsova E, Voortman J, Gilbert E, Berditchevski F. Tetraspanin CD82 regulates compartmentalisation and ligand-induced dimerization of EGFR. Journal of cell science. 2003; 116:4557-4566.
    • (2003) Journal of cell science , vol.116 , pp. 4557-4566
    • Odintsova, E.1    Voortman, J.2    Gilbert, E.3    Berditchevski, F.4
  • 35
    • 78649775562 scopus 로고    scopus 로고
    • Enrichment map: a network-based method for gene-set enrichment visualization and interpretation
    • Merico D, Isserlin R, Stueker O, Emili A, Bader GD. Enrichment map: a network-based method for gene-set enrichment visualization and interpretation. PloS one. 2010; 5:e13984.
    • (2010) PloS one , vol.5
    • Merico, D.1    Isserlin, R.2    Stueker, O.3    Emili, A.4    Bader, G.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.