In vivo metabolic spectroscopy identifies deficits in mitochondrial quality and capacity in aging skeletal muscle

Clinical Pharmacology and Therapeutics

Volumn 96, Issue 6, 2014, Pages 669-671

  Marcinek, D J ^a,b,c   Conley, K E ^a,b,c  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b University of Washington   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGING; ANIMAL; ENERGY METABOLISM; HUMAN; METABOLISM; MITOCHONDRIAL DISEASES; MITOCHONDRION; MOUSE; OXYGEN CONSUMPTION; SKELETAL MUSCLE; SPECTROSCOPY;

AGING; ANIMALS; ENERGY METABOLISM; HUMANS; MICE; MITOCHONDRIA; MITOCHONDRIAL DISEASES; MUSCLE, SKELETAL; OXYGEN CONSUMPTION; SPECTRUM ANALYSIS;

EID: 84925550652     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2014.179     Document Type: Article

References (5)

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3. Conley, K.E., Jubrias, S.A., Cress, M.E. & Esselman, P.C. Elevated energy coupling and aerobic capacity improves exercise performance in endurance-trained elderly subjects. Exp. Physiol. 98, 899-907 (2013).
4. Marcinek, D.J. & Siegel, M.P. Targeting redox biology to reverse mitochondrial dysfunction. Aging (Albany, NY). 5, 588-589 (2013).
5. Nicholls, D.G. & Ferguson, S.J. Bioenergetics 3 (Academic Press, London, 2002).