Changes in circulating endothelial cells count could become a valuable tool in the diagnostic definition of acute graft-versus-host disease

Transplantation

Volumn 98, Issue 7, 2014, Pages 706-712

  Almici, Camillo ^a   Skert, Cristina ^b   Verardi, Rosanna ^a   Di Palma, Andrea ^b   Bianchetti, Andrea ^a   Neva, Arabella ^a   Braga, Simona ^a   Malagola, Michele ^b   Turra, Alessandro ^b   Marini, Mirella ^a   Russo, Domenico ^b  

^a SPEDALI CIVILI   (Italy)

^b UNIVERSITY OF BRESCIA   (Italy)

Author keywords

Cellsearch system; Endothelial cells; Graft versus host disease; Hematopoietic stem cell transplantation

Indexed keywords

STEROID;

ACUTE GRAFT VERSUS HOST DISEASE; ACUTE LYMPHOBLASTIC LEUKEMIA; ACUTE MYELOBLASTIC LEUKEMIA; ADULT; ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; APLASTIC ANEMIA; ARTICLE; CELL COUNT; CHRONIC LYMPHATIC LEUKEMIA; CHRONIC MYELOID LEUKEMIA; CIRCULATING ENDOTHELIUM CELL; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENGRAFTMENT; FEMALE; HODGKIN DISEASE; HUMAN; HUMAN CELL; MALE; MULTIPLE MYELOMA; NONHODGKIN LYMPHOMA; PRIORITY JOURNAL; STEROID THERAPY; ADOLESCENT; ALLOTRANSPLANTATION; CELL SEPARATION; CLASSIFICATION; CYTOLOGY; GRAFT VS HOST DISEASE; HEMATOLOGIC NEOPLASMS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; IMMUNOSUPPRESSIVE TREATMENT; METABOLISM; MIDDLE AGED; PROCEDURES; PROSPECTIVE STUDY; RISK; VASCULAR ENDOTHELIUM;

ADOLESCENT; ADULT; CELL COUNT; CELL SEPARATION; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; FEMALE; GRAFT VS HOST DISEASE; HEMATOLOGIC NEOPLASMS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RISK; TRANSPLANTATION CONDITIONING; TRANSPLANTATION, HOMOLOGOUS;

EID: 84925546859     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0000000000000385     Document Type: Article

References (35)

1. Pidala J. Graft-vs-host disease following allogeneic hematopoietic cell transplantation. Cancer Control 2011; 18: 268.
2. Perez L, Anasetti C, Pidala J. Have we improved in preventing and treating acute graft-versus-host disease? Curr Opin Hematol 2011; 18: 408.
3. Barton-Burke M, Dwinell DM, Kafkas L, et al. Graft-versus-host disease: A complex long-Term side effect of hematopoietic stem cell transplant. Oncology (Williston Park). 2008; 22: 31.
4. Penack O, Gerard Socié G, van den Brink MRM. The importance of neovascularization and its inhibition for allogeneic hematopoietic stem cell transplantation. Blood 2011; 117: 4181.
5. Penack O, Henke E, Suh D, et al. Inhibition of neovascularization to simultaneously ameliorate graft-vs-host disease and decrease tumor growth. J Natl Cancer Inst 2010; 102: 894.
6. Biedermann BC. Vascular endothelium and graft-versus-host disease. Best Practice & Research Clinical Haematology 2008; 21: 129.
7. Tichelli A, Gratwhol A. Vascular endothelium as "novel" target of graft-versus-host disease. Best Pract Res Clin Hematol 2008; 21: 139.
8. Carreras E, Diaz-Ricart M. The role of the endothelium in the shortterm complications of hematopoietic SCT. Bone Marrow Transplant 2011; 46: 1495.
9. Blazar BR, Murphy WJ, Abedi M. Advances in graft-versus-host disease biology and therapy. Nat Rev Immunol 2012; 12: 443.
10. Leonhardt F, Grandmami S, Behe M, et al. Inflammatory neovascularization during graft-versus-host disease is regulated by av integrin and miR-100. Blood 2013; 121: 3307.
11. Choi SW, Levine JE, Ferrara JLM. Pathogenesis and management of graft-versus-host disease. Immunol Allergy Clin North Am 2010; 30: 75.
12. Komanduri KV. Targeting neovascularization in GVHD. Blood 2013; 121: 3303.
13. Biedermann BC, Sahner S, Gregor M, et al. Endothelial injury mediated by cytotoxic T lymphocytes and loss of microvessels in chronic graft versus host disease. Lancet 2002; 359: 2078.
14. Woywodt A, Scheer J, Hambach L, et al. Circulating endothelial cells as a marker of endothelial damage in allogeneic hematopoietic stem cell transplantation. Blood 2004; 103: 3603.
15. Dignan FL, Clark A, Amrolia P, et al. Diagnosis and management of acute graft-versus-host disease. Br J Haematol 2012; 158: 30.
16. Chen Y-B, Cutler CS. Biomarkers for acute GVHD: can we predict the unpredictable? Bone Marrow Transplant 2013; 48: 755.
17. Matsuda Y, Hara J, Osugi Y, et al. Serum levels of soluble adhesion molecules in stem cell transplantation-related complications. Bone Marrow Transplant 2001; 27: 977.
18. Cutler C, Kim HT, Ayanian S, et al. Prediction of veno-occlusive disease using biomarkers of endothelial injury. Biol Blood Marrow Transplant 2010; 16: 1180.
19. Pihusch V, Rank A, Steber R, et al. Endothelial cell-derived microparticles in allogenic hematopoietic stem cell recipients. Transplantation 2006; 81: 1405.
20. Almici C, Carlo-Stella C, Wagner JE, et al. Biologic and phenotypic analysis of early hematopoietic progenitor cells in umbilical cord blood. Leukemia 1997; 11: 2143.
21. Woywodt A, Streiber F, de Groot K, et al. Circulating endothelial cells as markers for ANCA-Associated small-vessel vasculitis. Lancet 2003; 361: 206.
22. Woywodt A, Schroeder M, Gwinner W, et al. Elevated numbers of circulating endothelial cells in renal transplant recipients. Transplantation 2003; 76: 1.
23. Damani S, Sacconi A, Libiger O, et al. Characterization of circulating endothelial cells in acute myocardial infarction. Sci Transl Med 2012; 4: 126-33.
24. Strijbos MH, Landburg PP, Nur E, et al. Circulating endothelial cells: A potential parameter of organ damage in sickle cell anemia? Blood Cells Mol Dis 2009; 43: 63.
25. Rowand JL, Martin G, Doyle GV, et al. Endothelial cells in peripheral blood of healthy subjects and patients with metastatic carcinomas. Cytometry A 2007; 71: 105.
26. Paczesny S. Discovery and validation of graft-versus-host disease biomarkers. Blood 2013; 121: 585.
27. Paczesny S, Krijanovski OI, Braun TM, et al. A biomarker panel for acute graft-versus-host disease. Blood 2009; 113: 273.
28. Bertolini F, Shaked Y, Mancuso P, et al. The multifaceted circulating endothelial cell in cancer: Towards marker and target identification. Nat Rev Cancer 2006; 6: 835.
29. Kraan J, Strijbos MH, Sieuwerts AM, et al. A new approach for rapid and reliable enumeration of circulating endothelial cells in patients. J Thromb Haemost 2012; 10: 931.
30. Furstenberger G, von Moos R, Lucas R, et al. Circulating endothelial cells and angiogenic serum factors during neoadjuvant chemotherapy of primary breast cancer. Br J Cancer 2006; 94: 524.
31. Widemann A, Sabatier F, Arnaud L, et al. CD146-based immunomagnetic enrichment followed by multiparameter flow cytometry: A new approach to counting circulating endothelial cells. J Thromb Haemost 2008; 6: 869.
32. Wolf D, von Lilienfeld-Toal M, Wolf AM, et al. Novel treatment concepts for graft-versus-host disease. Blood 2012; 119: 16.
33. Briscoe DM, Alexander SI, Lichtman AH. Interactions between T lymphocytes and endothelial cells in allograft rejection. Curr Opin Immunol 1998; 10: 525.
34. Cortesini R, Suciu-Foca N. ILT3+ ILT4+ tolerogenic endothelial cells in transplantation. Transplantation 2006; 82: S30.
35. Taflin C, Charron D, Glotz D, et al. Regulation of the CD4+ T cell allo-immune response by endothelial cells. Hum Immunol 2012; 73: 1269.