Identification of a small molecule signaling factor that regulates the biosynthesis of the antifungal polycyclic tetramate macrolactam HSAF in Lysobacter enzymogenes

Applied Microbiology and Biotechnology

Volumn 99, Issue 2, 2015, Pages 801-811

  Han, Yong ^a,b   Wang, Yan ^a,d   Tombosa, Simon ^a   Wright, Stephen ^a   Huffman, Justin ^a   Yuen, Gary ^a   Qian, Guoliang ^c   Liu, Fengquan ^c   Shen, Yuemao ^b   Du, Liangcheng ^a  

^a UNIVERSITY OF NEBRASKA LINCOLN   (United States)

^b SHANDONG UNIVERSITY   (China)

^c NANJING AGRICULTURAL UNIVERSITY   (China)

^d OCEAN UNIVERSITY OF CHINA   (China)

Author keywords

Diffusible signaling factor; HSAF; Lysobacter enzymogenes; Natural product biosynthesis; Regulation

Indexed keywords

ANTIBIOTICS; BIOCHEMISTRY; BIOSYNTHESIS; FATTY ACIDS; METABOLITES; MOLECULES; SIGNALING; TRANSCRIPTION;

DIFFUSIBLE SIGNALING FACTOR; HSAF; LYSOBACTER; NATURAL PRODUCTS; REGULATION;

FUNGI;

ANTIFUNGAL AGENT; CYCLIC AMP RECEPTOR; FATTY ACID; GREEN FLUORESCENT PROTEIN; POLYCYCLIC TETRAMATE MACROLACTAM; UNCLASSIFIED DRUG; BACTERIAL DNA; BACTERIAL PROTEIN;

ANTIFUNGAL ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG IDENTIFICATION; DRUG MANUFACTURE; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFRARED SPECTROSCOPY; LYSOBACTER; LYSOBACTER ENZYMOGENES; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; THIN LAYER CHROMATOGRAPHY; UPREGULATION; XANTHOMONAS CAMPESTRIS; ENZYMOLOGY; ESCHERICHIA COLI; GENETICS; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REPORTER GENE; SIGNAL TRANSDUCTION; TEMPERATURE;

ANTIFUNGAL AGENTS; BACTERIAL PROTEINS; DNA, BACTERIAL; ESCHERICHIA COLI; GENES, REPORTER; LYSOBACTER; MAGNETIC RESONANCE SPECTROSCOPY; SIGNAL TRANSDUCTION; TEMPERATURE;

EID: 84925536901     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-014-6120-x     Document Type: Article

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