Distinct ceramide synthases regulate polarized growth in the filamentous fungus Aspergillus nidulans

Molecular Biology of the Cell

Volumn 17, Issue 3, 2006, Pages 1218-1227

  Li, Shaojie ^a   Du, Liangcheng ^a   Yuen, Gary ^a   Harris, Steven D ^a  

^a UNIVERSITY OF NEBRASKA LINCOLN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CERAMIDE; SPHINGOLIPID;

ARTICLE; ASPERGILLUS NIDULANS; CYTOSKELETON; FUNGUS GROWTH; FUNGUS HYPHAE; FUNGUS SPORE; MEMBRANE STRUCTURE; NONHUMAN; PRIORITY JOURNAL;

ACYL COENZYME A; ANTIFUNGAL AGENTS; ASPERGILLUS NIDULANS; CELL POLARITY; DRUG RESISTANCE, FUNGAL; FUNGAL PROTEINS; HYPHAE; MIXED FUNCTION OXYGENASES; MODELS, BIOLOGICAL; MUTATION; OXIDOREDUCTASES; PHENOTYPE; PHYLOGENY; SACCHAROMYCES CEREVISIAE PROTEINS; SPHINGOLIPIDS;

BACTERIA (MICROORGANISMS); EMERICELLA NIDULANS; FUNGI;

EID: 33644866956     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E05-06-0533     Document Type: Article

References (46)

1. Bagnat, M., and Simons, K. (2002). Cell surface polarization during yeast mating. Proc. Natl. Acad. Sci. USA 99, 14183-14188.
2. Barrnicki-Garcia, S. (2002). Hyphal tip growth: outstanding questions. In: Molecular Biology of Fungal Development, ed. H. D. Osiewacz, New York: Marcel Dekker, 29-58.
3. Barrnicki-Garcia, S., and Lippman, E. (1969). Fungal morphogenesis: cell wall construction in Mucor rouxii. Science 165, 302-304.
4. Barz, W. P., and Walter, P. (1999). Two endoplasmic reticulum (ER) membrane proteins that facilitate ER-to-Golgi transport of glycosylphosphatidylinositol-anchored proteins. Mol. Biol. Cell 10, 1043-1059.
5. Bauer, Y., Knechtle, P., Wendland, J., Helfer, H., and Philippsen, P. (2004). A Ras-like GTPase is involved in hyphal growth guidance in the filamentous fungus Ashbya gossypii. Mol. Biol. Cell 15, 4622-4632.
6. Brugger, B., Graham, C., Leibrecht, I., Mombelli, E., Jen, A., Wieland, F., and Morris, R. (2004). The membrane domains occupied by glycosylphosphatidylinositol-anchored prion protein and Thy-1 differ in lipid composition. J. Biol. Chem. 279, 7530-7536.
7. Cheng, J., Park, T. S., Fischl, A. S., and Ye, X. S. (2001). Cell cycle progression and cell polarity require sphingolipid biosynthesis in Aspergillus nidulans. Mol. Cell. Biol. 21, 6198-6209.
8. Efimov, V. P. (2003). Roles of NUDE and NUDF proteins of Aspergillus nidulans: insights from intracellular localization and overexpression effects. Mol. Biol. Cell 14, 871-888.
9. Efimov, V. P., and Morris, N. R. (1998). A screen for dynein synthetic lethals in Aspergillus nidulans identifies spindle assembly checkpoint genes and other genes involved in mitosis. Genetics 349, 101-116.
10. Evangelista, M., Blundell, K., Longtine, M. S., Chow, C. J., Adames, N., Pringle, J. R., Peter, M., and Boone, C. (1997). Bni1p, a yeast formin linking Cdc42p and the actin cytoskeleton during polarized morphogenesis. Science 276, 118-122.
11. Futerman, A., and Hannun, Y. A. (2004). The complex life of simple sphingolipids. EMBO Rep. 5, 777-782.
12. Golub, T., and Caroni, P. (2005). PI(4,5)P2-dependent microdomain assemblies capture microtubules to promote and control leading edge motiliry. J. Cell Biol. 369, 151-165.
13. Gooday, G. W. (1971). An autoradiographic study of hyphal growth of some fungi. J. Gen. Microbiol. 67, 125-133.
14. Graupner, P. R., Thornburgh, S., Mathieson, J. T., Chapin, E. L., Kemmitt, G. M., Brown, J. M., and Snipes, C. E. (1997). Dihydromaltophilin; a novel fungicidal tetrameric acid containing metabolite from Streptomyces sp. J. Antibiot. 50, 1014-1019.
15. Guillas, I., Kirchman, P. A., Chuard, R., Pfefferli, M., Jiang, J. C., Jazwinski, S. M., and Conzelmann, A. (2001). C26-CoA-dependent ceramide synthesis of Saccharomyces cerevisiae is operated by Lag1p and Lac1p. EMBO J. 20, 2655-2665.
16. Guirland, C., Suzuki, S., Kojima, M., Lu, B., and Zheng, J. Q. (2004). Lipid rafts mediate chemotropic guidance of nerve growth cones. Neuron 42, 51-62.
17. Harris, S. D. (2001). Genetic analysis of ascomycete fungi. In: Molecular and Cellular Biology of Filamentous Fungi: Practical Approach, ed. N. Talbot, Oxford: Oxford University Press, 47-58.
18. Harris, S. D., and Momany, M. (2004). Polarity in filamentous fungi: moving beyond the yeast paradigm. Fungal Genet. Biol. 41, 391-400.
19. Harris, S. D., Morrell, J. L., and Hamer, J. E. (1994). Identification and characterization of Aspergillus nidulans mutants defective in cytokinesis. Genetics 336, 517-532.
20. Harris, S. D., Hamer, L., Sharpless, K. E., and Hamer, J. E. (1997). The Aspergillus nidulans sepA gene encodes an FH1/2 protein involved in cytokinesis and the maintenance of cellular polarity. EMBO J. 36, 3474-3483.
21. Harris, S. D., Read, N. D., Roberson, R. W., Shaw, B., Seiler, S., Plamann, M., and Momany, M. (2005). Polarisome meets Spitzenkorper: microscopy, genetics, and genomics converge. Euk. Cell 4, 225-229.
22. Higgs, H. N., and Peterson, K. J. (2005). Phylogenetic analysis of the formin homology 2 domain. Mol. Biol. Cell 16, 1-13.
23. Jakobi, M., Winkelmann, G., Kaiser, D., Kempler, C., Jung, G., Berg, G., and Bahl, H. (1996). Maltophilin: a new antifungal compound produced by Stenotrophomonas maltophila R3089. J. Antibiot. 49, 1101-1104.
24. Kafer, E. (1977). Meiotic and mitotic recombination in Aspergillus and its chromosomal aberrations. Adv. Genet. 19, 33-131.
25. Konzack, S., Rischitor, P. E., Enke, C., and Fischer, R. (2005). The role of the kinesin motor KipA in microtubule organization and polarized growth of Aspergillus nidulans. Mol. Biol. Cell 16, 497-506.
26. Li, S. (2005). An antifungal metabolite from Lysobacter enzymogenes strain C3, isolation, biological activity, mode of action and potential use in plant disease control. PhD thesis. University of Nebraska-Lincoln.
27. Marquardt, T., Shirasaki, R., Ghosh, S., Andrews, S. E., Carter, N., Hunter, T., and Pfaff, S. L. (2005). Coexpressed EphA receptors and ephrin-A ligands mediate opposing actions on growth cone navigation from distinct membrane domains. Cell 121, 127-139.
28. Martin, S., and Konopka, J. B. (2004). Lipid raft polarization contributes to hyphal growth in Candida albicans. Euk. Cell 3, 675-684.
29. Merrill, A. H., Jr. (2002). De novo sphingolipid biosynthesis: a necessary, but dangerous, pathway. J. Biol. Chem. 277, 25843-25846.
30. Munro, S. (2003). Lipid rafts: elusive or illusive. Cell 115, 377-388.
31. Oakley, B. R., and Osmani, S. A. (1993). Cell cycle analysis using the filamentous fungus Aspergillus nidulans. In: The Cell Cycle: Practical Approach, ed. P. Fantes, R. Brooks, Oxford: Oxford University Press, 127-142.
32. cdc25 in Aspergillus nidulans. EMBO J. 11, 2139-2149.
33. Osherov, N., and May, G. (2000). Conidial germination in Aspergillus nidulans requires RAS signaling and protein synthesis. Genetics 155, 647-656.
34. Pearson, C. L., Xu, K., Sharpless, K. E., and Harris, S. D. (2004). MesA, a novel fungal protein required for the stabilization of polarity axes in Aspergillus nidulans. Mol. Biol. Cell 15, 3658-3672.
35. Riebeling, C., Allegood, J. C., Wang, E., Merrill A. H., Jr., and Futerman, A. H. (2003). Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors. J. Biol. Chem. 278, 43452-43459.
36. Sagot, I., Klee, S. K., and Pellman, D. (2002). Yeast formins regulate cell polarity by controlling the assembly of actin cables. Nat. Cell. Biol. 4, 42-50.
37. Schorling, S., Vallee, B., Barz, W. P., Riezman, H., and Oesterhelt, D. (2001). Lag1p and Lac1p are essential for the Acyl-CoA-dependent ceramide synthase reaction in Saccharomyces ceremsiae. Mol. Biol. Cell 12, 3417-3427.
38. Sharpless, K. E., and Harris, S. D. (2002). Functional characterization and localization of the Aspergillus nidulans formin SEPA. Mol. Biol. Cell 13, 469-479.
39. Sheu, Y. J., Santos, B., Fortin, N., Costigan, C., and Snyder, M. (1998). Spa2p interacts with cell polarity proteins and signaling components involved in yeast cell morphogenesis. Mol. Cell. Biol. 18, 4053-4069.
40. Simons, K., and Toomre, D. (2000). Lipid rafts and signal transduction. Nat. Rev. Mol. Cell Biol. 1, 31-39.
41. Tsui-Pierchala, B. A., Encinas, M., Milbrandt, J., and Johnson, E. M., Jr. (2002). Lipid rafts in neuronal signaling and function. Trends Neurosci. 25, 412-417.
42. Valdez-Taubus, J., and Pelham, H. R. (2003). Slow diffusion of proteins in the yeast plasma membrane allows polarity to be maintained by endocytic cycling. Curr. Biol. 13, 1636-1640.
43. Vallee, B., and Riezman, H. (2005). Lip1, a novel subunit of acyl-CoA ceramide synthase. EMBO J. 24, 730-741.
44. Yang, L., Ukil, L., Osmani, A., Nahm, F., Davies, J., De Souza, C. P., Dou, X., Perez-Balaguer, A., and Osmani, S. A. (2004). Rapid production of gene replacement constructs and generation of a green fluorescent protein-tagged centromeric marker in Aspergillus nidulans. Euk. Cell 3, 1359-1362.
45. Yuen, G., Steadman, J. R., Lindegren, D. T., Schaff, D., and Jochum, C. (2001). Bean rust biological control using bacterial agents. Crop. Protect. 20, 395-402.
46. Zhang, Z., and Yuen, G. Y. (1999). Biological control of Bipolaris sorokiniana on tall fescue by Stenotrophomonas maltophilia strain C3. Phytopathology 89, 817-822.