Lupus and leprosy: beyond the coincidence

Immunologic Research

Volumn 61, Issue 1-2, 2015, Pages 160-163

  Ribeiro, F M ^a   Gomez, V E ^a   Albuquerque, E M N ^a   Klumb, E M ^a   Shoenfeld, Y ^b,c  

^a STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b SHEBA MEDICAL CENTER   (Israel)

^c TEL AVIV UNIVERSITY   (Israel)

Author keywords

Hansen disease; Leprosy; Systemic lupus erythematosus

Indexed keywords

AZATHIOPRINE; CYCLOPHOSPHAMIDE; HYDROXYCHLOROQUINE; MYCOPHENOLATE MOFETIL; PREDNISONE; STEROID; IMMUNOSUPPRESSIVE AGENT;

ADAPTIVE IMMUNITY; ADULT; AFRICAN AMERICAN; ANOREXIA; ANTIBODY PRODUCTION; ARTHRALGIA; ARTICLE; BRAZILIAN; CASE REPORT; COMBINATION CHEMOTHERAPY; COMPLEMENT BLOOD LEVEL; CYTOMEGALOVIRUS; DISEASE ASSOCIATION; DISEASE EXACERBATION; DRUG MEGADOSE; EPSTEIN BARR VIRUS; FATIGUE; FEMALE; GLOMERULONEPHRITIS; HEMOLYTIC ANEMIA; HUMAN; HUMAN PARVOVIRUS B19; HUMAN TISSUE; LEPROMATOUS LEPROSY; LOW DRUG DOSE; LUPUS ERYTHEMATOSUS NEPHRITIS; MALE; METABOLIC SYNDROME X; MOLECULAR MIMICRY; MUCINOSIS; MYCOBACTERIUM LEPRAE; NEPHRITIS; PAUCIBACILLARY LEPROSY; POLYARTHRITIS; PRIORITY JOURNAL; PROTEINURIA; PUNCH BIOPSY; RASH; REMISSION; SKIN BIOPSY; SKIN EXAMINATION; SYSTEMIC LUPUS ERYTHEMATOSUS; TREATMENT RESPONSE; TUBERCULOSIS; VASCULITIS; BIOPSY; COMPLICATION; LEPROSY; LUPUS ERYTHEMATOSUS, SYSTEMIC; TREATMENT OUTCOME;

ADULT; BIOPSY; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; LEPROSY; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; TREATMENT OUTCOME;

EID: 84925534804     PISSN: 0257277X     EISSN: 15590755     Source Type: Journal    
DOI: 10.1007/s12026-014-8596-y     Document Type: Article

References (42)

1. Hsu TC, Tsay GJ. Human parvovirus B19 infection in patients with systemic lupus erythematosus. Rheumatology (Oxford). 2001;40:152–7.
2. Hemauer A, Beckenlehner K, Wolf H, Lang B, Modrow S. Acute parvovirus B19 infection in connection with a flare of systemic lupus erythematodes in a female patient. J Clin Virol. 1999;14:73–7.
3. Goddard GZ, Shoenfeld Y. Infections and SLE. Autoimmunity. 2005;38:473–85.
4. Hayashi T, Lee S, Ogasawara H, Sekigawa I. Exacerbation of systemic lupus erythematosus related to cytomegalovirus infection. Lupus. 1998;7:561–4.
5. Francis L, Perl A. Infection in systemic lupus erythematosus: friend or foe? Int J Clin Rheumtol. 2010;5:59–74.
6. Ribeiro FM, Szyper-Kravitz M, Klumb EM, et al. Can lupus flares be associated with tuberculosis infection? Clin Rev Allergy Immunol. 2010;38:163–8.
7. Shoenfeld Y, Isenberg DA. Mycobacteria and autoimmunity. Immunol Today. 1988;9:178–81.
8. Sela O, El-Roeiy A, DA Isenberg J, et al. A common anti-DNA antibody idiotype in sera of patients with active pulmonary tuberculosis. Arthritis Rheum. 1987;30:50–5.
9. Carducci R, Teralbini CGL, Tak CG. Autoantibodies in leprosy. Int J Lepr. 1978;58:171–5.
10. Guedes Barbosa LS, Gilbrut B, Shoenfeld Y, Sheinberg MA. Autoantibodies in leprosy sera. Clin Rheumatol. 1996;15:26–8.
11. Eichelmann K, González González SE, Salas-Alanis JC, Ocampo-Candiani J. Leprosy. An update: definition, pathogenesis, classification, diagnosis, and treatment. Actas Dermosifiliogr. 2013;104:554–63.
12. Global leprosy situation. Wkly Epidemiol Rec. 2010;85:337–48.
13. Gulia A, Fried I, Massone C. New insights in the pathogenesis and genetics of leprosy. F1000 Medicine Reports. 2010;27:2.
14. Scollard DM, Adams LB, Gillis TP, Krahenbuhl JL, Truman RW, Williams DL. The continuing challenges of leprosy. Clin Microbiol Rev. 2006;19:338–81.
15. Demangel C, Britton WJ. Interaction of dendritic cells with mycobacteria: where the action starts. Immunol Cell Biol. 2000;78:318–24.
16. Rodrigues LS, da Silva Maeda E, et al. Mycobacterium leprae induces insulin-like growth factor and promotes survival of Schwann cells upon serum withdrawal. Cell Microbiol. 2010;12:42–54.
17. Scollard DM, Smith T, Bhoopat L, Theetranont C, Rangdaeng S, Morens DM. Epidemiologic characteristics of leprosy reactions. Int J Lepr Other Mycobact Dis. 1994;1994(62):559–67.
18. Kumar B, Dogra S, Kaur I. Epidemiological characteristics of leprosy reactions: 15 years experience from North India. Int J Lepr Other Mycobact Dis. 2004;72:125–33.
19. Salvi S, Chopra A. Leprosy in a rheumatology setting: a challenging mimic to expose. Clin Rheumatol. 2013;32:1557–63.
20. Teixeira Júnior GJ, Silva CEF, Magalhães V. Application of the diagnostic criteria for systemic lupus erythematosus to patients with multibacillary leprosy. Rev Soc Bras Med Trop. 2011;44:85–90.
21. la Torre Garcia-de. I. Autoimmune phenomena in leprosy, particularly antinuclear antibodies and rheumatoid factor. J Rheumatol. 1993;20:900–3.
22. Kroumpouzos G, Vareltzidis A, Konstadoulakis MM, et al. Evaluation of the autoimmune response in leprosy. Lepr Rev. 1993;64:199–207.
23. Miller RA, Wener MH, Harnisch JP, Gilliland BC. The limited spectrum of antinuclear antibodies in leprosy. J Rheumatol. 1987;14:108–10.
24. Sharma VK, Saha K, Sehgal VN. Serum immunoglobulins and autoantibodies during and after erythema nodosum leprosum (ENL). Int J Lepr Other Mycobact Dis. 1982;50:159–63.
25. Masala C, Amendolea MA, Nuti M, Riccarducci R, Tarabini CG, Tarabini CG. Autoanibodies in leprosy. Int J Lepr Other Mycobac Dis. 1979;47:171–5.
26. Guedes-Barbosa LS, Gilbrut B, Shoenfeld Y, Scheinberg MA. Autoantibodies in leprosy sera. Clin Rheumatol. 1996;15:26–8.
27. Zandman-Goddard G, Blank M, Shoenfeld Y. Antiphospholipid antibodies and infections-drugs. In: Asherson RA, Cervera R, Piette JC, Shoenfeld Y, editors. The antiphospholipid syndrome II. Amsterdan: Elsevier Science; 2002. p. 343–60.
28. Elbeialy A, Strassburger-Lorna K, Altsumi T, et al. Antiphospholipid antibodies in leprotic patients: a correlation with disease manifestation. Clin Exp Rheumatol. 2000;18:492–4.
29. Loizou S, Singh S, Wypkema E, Asherson RA. Anticardiolipin anti- beta2-glycoprotein I and antiprothrombin antibodies in black South African patients with infectious disease. Ann Rheum Dis. 2003;62:1106–11.
30. de Laranaga GF, Forastiero RR, Martinuzzo ME, et al. High prevalence of antiphospholipid antibodies in leprosy: evaluation of antigen reactivity. Lupus. 2000;9:594–600.
31. Bonfa E, Llovet R, Scheinberg M, de Souza JM, Elkon KB. Comparison between autoantibodies in malaria and leprosy with lupus. Clin Exp Immunol. 1987;70:529–37.
32. Hojnik M, Gilburd B, Ziporen L, et al. Anticardiolipin antibodies in infections are heterogeneous in their dependency on ß2-GPI: analysis of anticardiolipina antibodies in leprosy. Lupus. 1994;3:515–21.
33. Levy RA, Pierangeli SA, Espinola RG. Antiphospholipid beta-2 glycoprotein I dependency assay to determine antibody pathogenicity. Arthritis Rheuma. 2000;43(suppl):I476.
34. Ribeiro SLE, Pereira HLA, Silva NP, Souza AWS, Sato EI. Anti- ß2 glycoprotein I antibodies are highly prevalent in a large number of Brazilian leprosy patients. Acta Reumatol Port. 2011;36:30–7.
35. Asherson RA, Shoenfeld Y. The role of infections in the pathogenesis of catasthrophic antiphospholipid syndrome—molecular mimicry? J Rheumatol. 2000;27:12–4.
36. Shoenfeld Y, Isenberg DA. Mycobacteria and autoimmunity. Immunol Today. 1988;9:178–81.
37. Shoenfeld Y, Vilner Y, Coates AR, et al. Monoclonal anti- tuberculosis antibodies react with DNA and monoclonal anti- DNA autoantibodies react with Mycobacterium tuberculosis. Clin Exp Immunol. 1986;66:255–61.
38. Amital-Teplizic H, Avinoach I, Coates AR, Kooperman O, Blank M, Shoenfeld Y. Binding of monoclonal anti-DNA and anti-TB glycolipids to brain tissue. Autoimmunity. 1989;4:277–87.
39. Sela O, El-Roeiy A, Isenberg DA, et al. A common anti-DNA antibody idiotype in sera of patients with active pulmonary tuberculosis. Arthritis Rheum. 1987;30:50–5.
40. Mackworth-Young CG, Sabbaga J, Schwartz RS. Idiotypic markers of polyclonal B cell activation. Public idiotypes shared by monoclonal antibodies derived from patients with systemic lupus erythematosus or leprosy. J Clin Invest. 1987;79:572–81.
41. Mackworth-Young CG. Cross-reactive idiotypes in sera from patients with leprosy, lupus and Lyme disease and from healthy individuals. Clin Exp Immunol. 1990;79:78–82.
42. Mackworth-Young CG, Cairns E, Sabbaga J, et al. Comparative study of idiotypes on monoclonal antibodies derived from patients with lupus and leprosy and from normal individuals. J Autoimmunity. 1990;3:415–9.