Hippocampal Volume in Healthy Controls Given 3-Day Stress Doses of Hydrocortisone

Neuropsychopharmacology

Volumn 40, Issue , 2015, Pages 1216-1221

  Brown, E Sherwood ^a   Jeon Slaughter, Haekyung ^a   Lu, Hanzhang ^b   Jamadar, Rhoda ^a   Issac, Sruthy ^a   Shad, Mujeeb ^a   Denniston, Daren ^a   Tamminga, Carol ^a   Nakamura, Alyson ^a   Thomas, Binu P ^b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROCORTISONE; PHENYTOIN; PLACEBO; CENTRAL NERVOUS SYSTEM AGENTS;

ADULT; ARTICLE; BRAIN SIZE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; HIPPOCAMPUS; HUMAN; HUMAN EXPERIMENT; HYDROCORTISONE BLOOD LEVEL; MALE; NORMAL HUMAN; PILOT STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEX DIFFERENCE; COMPARATIVE STUDY; DRUG EXPOSURE; MENSTRUAL CYCLE; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; VOLUMETRY; ADOLESCENT; BLOOD; DRUG EFFECTS; MIDDLE AGED; ORGAN SIZE; PATHOLOGY; TIME FACTOR; YOUNG ADULT;

ADOLESCENT; ADULT; CENTRAL NERVOUS SYSTEM AGENTS; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; FEMALE; HIPPOCAMPUS; HUMANS; HYDROCORTISONE; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; ORGAN SIZE; PHENYTOIN; PILOT PROJECTS; TIME FACTORS; YOUNG ADULT;

EID: 84925502994     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2014.307     Document Type: Article

References (41)

1. Almela M, Hidalgo V, Villada C, Espin L, Gomez-Amor J, Salvador A (2011). The impact of cortisol reactivity to acute stress on memory: sex differences in middle-aged people. Stress 14: 117-127.
2. Behrens PF, Ostertag CB, Warnke PC (1998). Regional cerebral blood flow in peritumoral brain edema during dexamethasone treatment: a xenon-enhanced computed tomographic study. Neurosurgery 43: 235-240 discussion 240-241.
3. Bender BG, Lerner JA, Kollasch E (1988). Mood and memory changes in asthmatic children receiving corticosteroids. J Am Acad Child Adolesc Psychiatry 27: 720-725.
4. Breitberg A, Drevets WC, Wood SE, Mah L, Schulkin J, Sahakian BJ et al (2013). Hydrocortisone infusion exerts dose- and sexdependent effects on attention to emotional stimuli. Brain Cogn 81: 247-255.
5. Brown ES (2009). Effects of glucocorticoids on mood, memory, and the hippocampus. Treatment and preventive therapy. Ann NY Acad Sci 1179: 41-55.
6. Brown ES, Beard L, Frol AB, Rush AJ (2006). Effect of two prednisone exposures on mood and declarative memory. Neurobiol Learn Mem 86: 28-34.
7. Brown ES, J Woolston D, Frol A, Bobadilla L, Khan DA, Hanczyc M et al (2004). Hippocampal volume, spectroscopy, cognition, and mood in patients receiving corticosteroid therapy. Biol Psychiatry 55: 538-545.
8. Brown ES, Lu H, Denniston D, Uh J, Thomas BP, Carmody TJ et al (2013). A randomized, placebo-controlled proof-of-concept, crossover trial of phenytoin for hydrocortisone-induced declarative memory changes. J Affect Disord 150: 551-558.
9. Brown ES, Wolfshohl J, Shad MU, Vazquez M, Osuji IJ (2008). Attenuation of the effects of corticosteroids on declarative memory with lamotrigine. Neuropsychopharmacology 33: 2376-2383.
10. Chumas P, Condon B, Oluoch-Olunya D, Griffiths S, Hadley D, Teasdale G (1997). Early changes in peritumorous oedema and contralateral white matter after dexamethasone: a study using proton magnetic resonance spectroscopy. J Neurol, Neurosur Psychiatry 62: 590-595.
11. Fardet L, Petersen I, Nazareth I (2012). Suicidal behavior and severe neuropsychiatric disorders following glucocorticoid therapy in primary care. Am J Psychiatry 169: 491-497.
12. First MB, Spitzer RL, Gibbon M, Williams JBW (1995). Structured Clinical Interview for DSM-IV Axis I Disorders. Biometrics Research Department, NY State Psychiatric Institute: New York, NY, USA.
13. Galea LA, McEwen BS, Tanapat P, Deak T, Spencer RL, Dhabhar FS (1997). Sex differences in dendritic atrophy of CA3 pyramidal neurons in response to chronic restraint stress. Neuroscience 81: 689-697.
14. Gilbert AR, Rosenberg DR, Harenski K, Spencer S, Sweeney JA, Keshavan MS (2001). Thalamic volumes in patients with firstepisode schizophrenia. Am J Psychiatry 158: 618-624.
15. Hamilton M (1960). A rating scale for depression. J Neurol Neurosur Psychiatry 23: 56-62.
16. Judd LL, Schettler PJ, Brown ES, Wolkowitz OM, Sternberg EM, Bender BG et al (2014). Adverse Consequences of Glucocorticoid Medication: Psychological, Cognitive, and Behavioral Effects. AmJ Psychiatry 171: 1045-1051.
17. Leverenz JB, Wilkinson CW, Wamble M, Corbin S, Grabber JE, Raskind MA et al (1999). Effect of chronic high-dose exogenous cortisol on hippocampal neuronal number in aged nonhuman primates. J Neurosci 19: 2356-2361.
18. Magarinos AM, Verdugo JM, McEwen BS (1997). Chronic stress alters synaptic terminal structure in hippocampus. Proc Natl Acad SciUSA 94: 14002-14008.
19. Magnotta VA, Harris G, Andreasen NC, O'Leary DS, Yuh WT, Heckel D (2002). Structural MR image processing using the BRAINS2 toolbox. Comput Med Imaging Graph 26: 251-264.
20. McEwen BS, Conrad CD, Kuroda Y, Frankfurt M, Magarinos AM, McKittrick C (1997). Prevention of stress-induced morphological and cognitive consequences. Eur Neuropsychopharmacol 7(Suppl 3): S323-S328.
21. Newcomer JW, Selke G, Melson AK, Hershey T, Craft S, Richards K et al (1999). Decreased memory performance in healthy humans induced by stress-level cortisol treatment. Arch Gen Psychiatry 56: 527-533.
22. Petereit LB, Meikle AW (1977). Effectiveness of prednisolone during phenytoin therapy. Clin Pharmacol Ther 22: 912-916.
23. Protopopescu X, Butler T, Pan H, Root J, Altemus M, Polanecsky M et al (2008). Hippocampal structural changes across the menstrual cycle. Hippocampus 18: 985-988.
24. Reagan LP, McEwen BS (1997). Controversies surrounding glucocorticoid-mediated cell death in the hippocampus. J Chem Neuroanat 13: 149-167.
25. Reul JM, de Kloet ER (1985). Two receptor systems for corticosterone in rat brain: microdistribution and differential occupation. Endocrinology 117: 2505-2511.
26. Ryan JJ, Geisser ME, Randall DM, Georgemiller RJ (1986). Alternate form reliability and equivalency of the Rey Auditory Verbal Learning Test. J Clin Exp Neuropsychol 8: 611-616.
27. Saaltink DJ, Vreugdenhil E (2014). Stress, glucocorticoid receptors, and adult neurogenesis: a balance between excitation and inhibition? Cell Mol Life Sci 71: 2499-2515.
28. Sapolsky RM, Uno H, Rebert CS, Finch CE (1990). Hippocampal damage associated with prolonged glucocorticoid exposure in primates. J Neurosci 10: 2897-2902.
29. Scheel M, Strohle A, Bruhn H (2010). Effects of short-term stress-like cortisol on cerebral metabolism: a proton magnetic resonance spectroscopy study at 3.0 T. J Psychiatr Res 44: 521-526.
30. Senn S (2006). Cross-over trials in statistics in medicine: the first '25' years. Stat Med 25: 3430-3442.
31. Shenton ME, Dickey CC, Frumin M, McCarley RW (2001). A review of MRI findings in schizophrenia. Schizophr Res 49: 1-52.
32. Shenton ME, Gerig G, McCarley RW, Szekely G, Kikinis R (2002). Amygdala-hippocampal shape differences in schizophrenia: the application of 3D shape models to volumetric MR data. Psychiatry Res 115: 15-35.
33. Shors TJ, Chua C, Falduto J (2001). Sex differences and opposite effects of stress on dendritic spine density in the male versus female hippocampus. J Neurosci 21: 6292-6297.
34. Starkman MN, Gebarski SS, Berent S, Schteingart DE (1992). Hippocampal formation volume, memory dysfunction, and cortisol levels in patients with Cushing's syndrome. Biol Psychiatry 32: 756-765.
35. Sternberg EM, Judd LL (2009). Conference summary and conclusions. A comprehensive approach to predicting and managing mood effects of glucocorticoids. Ann NY Acad Sci 1179: 229-233.
36. Tessner KD, Walker EF, Dhruv SH, Hochman K, Hamann S (2007). The relation of cortisol levels with hippocampus volumes under baseline and challenge conditions. Brain Res 1179: 70-78.
37. Uno H, Eisele S, Sakai A, Shelton S, Baker E, DeJesus O et al (1994). Neurotoxicity of glucocorticoids in the primate brain. Horm Behav 28: 336-348.
38. Uno H, Tarara R, Else JG, Suleman MA, Sapolsky RM (1989). Hippocampal damage associated with prolonged and fatal stress in primates. J Neurosci 9: 1705-1711.
39. Vyas A, Mitra R, Shankaranarayana Rao BS, Chattarji S (2002). Chronic stress induces contrasting patterns of dendritic remodeling in hippocampal and amygdaloid neurons. J Neurosci 22: 6810-6818.
40. Watanabe Y, Gould E, Cameron HA, Daniels DC, McEwen BS (1992). Phenytoin prevents stress- and corticosterone-induced atrophy of CA3 pyramidal neurons. Hippocampus 2: 431-435.
41. Wolf OT, Schommer NC, Hellhammer DH, McEwen BS, Kirschbaum C (2001). The relationship between stress induced cortisol levels and memory differs between men and women. Psychoneuroendocrinology 26: 711-720.