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Volumn 40, Issue 2, 2015, Pages 336-352

Classification of Subpopulations of Cells Within Human Primary Brain Tumors by Single Cell Gene Expression Profiling

Author keywords

Astrocytoma grade IV; Glioblastoma multiforme; Oligodendroglioma grade III; Single cell gene expression profiling

Indexed keywords

ADULT; ASTROCYTOMA; BRAIN CELL; BRAIN TISSUE; BRAIN TUMOR; CANCER GRADING; CANCER TISSUE; CASE REPORT; CELL SUBPOPULATION; CELL VIABILITY; CONTROLLED STUDY; DATA ANALYSIS; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MIDDLE AGED; OLIGODENDROGLIOMA; ONCOGENESIS AND MALIGNANT TRANSFORMATION; PRIMARY TUMOR; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; SINGLE CELL ANALYSIS; TUMOR CELL; TUMOR GENE; TUMOR MICROENVIRONMENT; TUMOR PENUMBRA; CLASSIFICATION; GENETICS; PATHOLOGY;

EID: 84925466663     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-014-1431-y     Document Type: Review
Times cited : (7)

References (65)
  • 2
    • 84882582801 scopus 로고    scopus 로고
    • Single-cell gene expression analysis reveals genetic associations masked in whole-tissue experiments
    • COI: 1:CAS:528:DC%2BC3sXhtFCisr7E, PID: 23873083
    • Wills QF, Livak KJ, Tipping AJ, Enver T, Goldson AJ, Sexton DW, Holmes C (2013) Single-cell gene expression analysis reveals genetic associations masked in whole-tissue experiments. Nat Biotechnol 31(8):748–752. doi:10.1038/nbt.2642
    • (2013) Nat Biotechnol , vol.31 , Issue.8 , pp. 748-752
    • Wills, Q.F.1    Livak, K.J.2    Tipping, A.J.3    Enver, T.4    Goldson, A.J.5    Sexton, D.W.6    Holmes, C.7
  • 3
    • 77953121190 scopus 로고    scopus 로고
    • Single cell analysis: the new frontier in ‘omics’
    • COI: 1:CAS:528:DC%2BC3cXmsVensrk%3D, PID: 20434785
    • Wang D, Bodovitz S (2010) Single cell analysis: the new frontier in ‘omics’. Trends Biotechnol 28(6):281–290. doi:10.1016/j.tibtech.2010.03.002
    • (2010) Trends Biotechnol , vol.28 , Issue.6 , pp. 281-290
    • Wang, D.1    Bodovitz, S.2
  • 7
    • 79952323055 scopus 로고    scopus 로고
    • Defining cell populations with single-cell gene expression profiling: correlations and identification of astrocyte subpopulations
    • PID: 21112872
    • Ståhlberg A, Andersson D, Aurelius J, Faiz M, Pekna M, Kubista M, Pekny M (2011) Defining cell populations with single-cell gene expression profiling: correlations and identification of astrocyte subpopulations. Nucleic Acids Res 39(4):e24. doi:10.1093/nar/gkq1182
    • (2011) Nucleic Acids Res , vol.39 , Issue.4 , pp. e24
    • Ståhlberg, A.1    Andersson, D.2    Aurelius, J.3    Faiz, M.4    Pekna, M.5    Kubista, M.6    Pekny, M.7
  • 8
    • 84936881907 scopus 로고    scopus 로고
    • 2013, Socialstyrelsen, Cancerfonden, Stockholm:
    • Socialstyrelsen Cancerfonden (2013) Cancer i siffror 2013, vol 2013. Socialstyrelsen, Cancerfonden, Stockholm
    • (2013) Cancer i siffror 2013
    • Socialstyrelsen, C.1
  • 9
    • 20344407807 scopus 로고    scopus 로고
    • Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas
    • COI: 1:CAS:528:DC%2BD2MXlvVSgsbg%3D, PID: 15977639
    • Ohgaki H, Kleihues P (2005) Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas. J Neuropathol Exp Neurol 64(6):479–489
    • (2005) J Neuropathol Exp Neurol , vol.64 , Issue.6 , pp. 479-489
    • Ohgaki, H.1    Kleihues, P.2
  • 10
    • 1942438972 scopus 로고    scopus 로고
    • Regional heterogeneity of EGFR gene amplification and nuclear morphology in glioblastomas. An investigation using laser microdissection and pressure catapulting
    • PID: 15131893
    • Nafe R, Glienke W, Burgemeister R, Gangnus R, Haar B, Pries A, Schlote W (2004) Regional heterogeneity of EGFR gene amplification and nuclear morphology in glioblastomas. An investigation using laser microdissection and pressure catapulting. Anal Quant Cytol Histol 26(2):65–76
    • (2004) Anal Quant Cytol Histol , vol.26 , Issue.2 , pp. 65-76
    • Nafe, R.1    Glienke, W.2    Burgemeister, R.3    Gangnus, R.4    Haar, B.5    Pries, A.6    Schlote, W.7
  • 11
    • 0019462206 scopus 로고
    • Isolation, karyotype, and clonal growth of heterogeneous subpopulations of human malignant gliomas
    • COI: 1:STN:280:DyaL3M3gvF2ntg%3D%3D, PID: 7016313
    • Shapiro JR, Yung WK, Shapiro WR (1981) Isolation, karyotype, and clonal growth of heterogeneous subpopulations of human malignant gliomas. Cancer Res 41(6):2349–2359
    • (1981) Cancer Res , vol.41 , Issue.6 , pp. 2349-2359
    • Shapiro, J.R.1    Yung, W.K.2    Shapiro, W.R.3
  • 14
    • 33745726808 scopus 로고    scopus 로고
    • Brain tumour stem cells
    • COI: 1:CAS:528:DC%2BD28XkvVylt78%3D, PID: 16723989
    • Vescovi AL, Galli R, Reynolds BA (2006) Brain tumour stem cells. Nat Rev Cancer 6(6):425–436. doi:10.1038/nrc1889
    • (2006) Nat Rev Cancer , vol.6 , Issue.6 , pp. 425-436
    • Vescovi, A.L.1    Galli, R.2    Reynolds, B.A.3
  • 15
    • 79958849271 scopus 로고    scopus 로고
    • Heterogeneity maintenance in glioblastoma: a social network
    • COI: 1:CAS:528:DC%2BC3MXnsFKiu74%3D, PID: 21628493
    • Bonavia R, Inda MM, Cavenee WK, Furnari FB (2011) Heterogeneity maintenance in glioblastoma: a social network. Cancer Res 71(12):4055–4060. doi:10.1158/0008-5472.CAN-11-0153
    • (2011) Cancer Res , vol.71 , Issue.12 , pp. 4055-4060
    • Bonavia, R.1    Inda, M.M.2    Cavenee, W.K.3    Furnari, F.B.4
  • 17
    • 40449141013 scopus 로고    scopus 로고
    • What is principal component analysis?
    • COI: 1:CAS:528:DC%2BD1cXjsVGitrg%3D, PID: 18327243
    • Ringner M (2008) What is principal component analysis? Nat Biotechnol 26(3):303–304. doi:10.1038/nbt0308-303
    • (2008) Nat Biotechnol , vol.26 , Issue.3 , pp. 303-304
    • Ringner, M.1
  • 18
    • 0020068152 scopus 로고
    • Self-Organized Formation of Topologically Correct Feature Maps
    • Kohonen T (1982) Self-Organized Formation of Topologically Correct Feature Maps. Biol Cybern 43(1):59–69. doi:10.1007/Bf00337288
    • (1982) Biol Cybern , vol.43 , Issue.1 , pp. 59-69
    • Kohonen, T.1
  • 19
    • 84944178665 scopus 로고
    • Hierarchical grouping to optimize an objective function
    • Ward JH (1963) Hierarchical grouping to optimize an objective function. J Am Stat Assoc 58(301):236–244. doi:10.2307/2282967
    • (1963) J Am Stat Assoc , vol.58 , Issue.301 , pp. 236-244
    • Ward, J.H.1
  • 20
    • 0002322469 scopus 로고
    • On a test of whether one of two random variables is stochastically larger than the other
    • Mann HB, Whitney DR (1947) On a test of whether one of two random variables is stochastically larger than the other. Ann Math Stat 18(1):50–60
    • (1947) Ann Math Stat , vol.18 , Issue.1 , pp. 50-60
    • Mann, H.B.1    Whitney, D.R.2
  • 21
    • 84943987463 scopus 로고
    • Multiple comparisons among means
    • Dunn OJ (1961) Multiple comparisons among means. J Am Stat Assoc 56(293):52–64
    • (1961) J Am Stat Assoc , vol.56 , Issue.293 , pp. 52-64
    • Dunn, O.J.1
  • 22
    • 0034305621 scopus 로고    scopus 로고
    • Glial fibrillary acidic protein: GFAP-thirty-one years (1969-2000)
    • COI: 1:CAS:528:DC%2BD3cXns1eiuro%3D, PID: 11059815
    • Eng LF, Ghirnikar RS, Lee YL (2000) Glial fibrillary acidic protein: GFAP-thirty-one years (1969-2000). Neurochem Res 25(9–10):1439–1451
    • (2000) Neurochem Res , vol.25 , Issue.9-10 , pp. 1439-1451
    • Eng, L.F.1    Ghirnikar, R.S.2    Lee, Y.L.3
  • 24
    • 0024535322 scopus 로고
    • Differential ultrastructural localization of myelin basic protein, myelin/oligodendroglial glycoprotein, and 2′,3′-cyclic nucleotide 3′-phosphodiesterase in the CNS of adult rats
    • COI: 1:CAS:528:DyaL1MXlsVyguw%3D%3D, PID: 2462020
    • Brunner C, Lassmann H, Waehneldt TV, Matthieu JM, Linington C (1989) Differential ultrastructural localization of myelin basic protein, myelin/oligodendroglial glycoprotein, and 2′,3′-cyclic nucleotide 3′-phosphodiesterase in the CNS of adult rats. J Neurochem 52(1):296–304
    • (1989) J Neurochem , vol.52 , Issue.1 , pp. 296-304
    • Brunner, C.1    Lassmann, H.2    Waehneldt, T.V.3    Matthieu, J.M.4    Linington, C.5
  • 25
    • 0023161086 scopus 로고
    • Neuron specific enolase, a clinically useful marker for neurons and neuroendocrine cells
    • COI: 1:CAS:528:DyaL2sXhslWmur8%3D, PID: 3551759
    • Marangos PJ, Schmechel DE (1987) Neuron specific enolase, a clinically useful marker for neurons and neuroendocrine cells. Annu Rev Neurosci 10:269–295. doi:10.1146/annurev.ne.10.030187.001413
    • (1987) Annu Rev Neurosci , vol.10 , pp. 269-295
    • Marangos, P.J.1    Schmechel, D.E.2
  • 26
    • 27144500187 scopus 로고    scopus 로고
    • Expression of neurodevelopmental markers by cultured porcine neural precursor cells
    • PID: 16100001
    • Schwartz PH, Nethercott H, Kirov II, Ziaeian B, Young MJ, Klassen H (2005) Expression of neurodevelopmental markers by cultured porcine neural precursor cells. Stem Cells 23(9):1286–1294. doi:10.1634/stemcells.2004-0306
    • (2005) Stem Cells , vol.23 , Issue.9 , pp. 1286-1294
    • Schwartz, P.H.1    Nethercott, H.2    Kirov, I.I.3    Ziaeian, B.4    Young, M.J.5    Klassen, H.6
  • 27
    • 79953231162 scopus 로고    scopus 로고
    • Regional and laminar differences in antigen profiles and spatial distributions of astrocytes in the mouse hippocampus, with reference to aging
    • COI: 1:CAS:528:DC%2BC3MXktF2gt7k%3D, PID: 21320577
    • Jinno S (2011) Regional and laminar differences in antigen profiles and spatial distributions of astrocytes in the mouse hippocampus, with reference to aging. Neuroscience 180:41–52. doi:10.1016/j.neuroscience.2011.02.013
    • (2011) Neuroscience , vol.180 , pp. 41-52
    • Jinno, S.1
  • 28
    • 78650914558 scopus 로고    scopus 로고
    • Tubulin-independent tau in Alzheimer’s disease and cancer: implications for disease pathogenesis and treatment
    • COI: 1:CAS:528:DC%2BC3MXis1Onsw%3D%3D, PID: 20678073
    • Souter S, Lee G (2010) Tubulin-independent tau in Alzheimer’s disease and cancer: implications for disease pathogenesis and treatment. Curr Alzheimer Res 7(8):697–707
    • (2010) Curr Alzheimer Res , vol.7 , Issue.8 , pp. 697-707
    • Souter, S.1    Lee, G.2
  • 30
    • 0030861110 scopus 로고    scopus 로고
    • Mutual requirement of CDK4 and Myc in malignant transformation: evidence for cyclin D1/CDK4 and p16INK4A as upstream regulators of Myc
    • COI: 1:CAS:528:DyaK2sXkvFClsbw%3D, PID: 9244353
    • Haas K, Staller P, Geisen C, Bartek J, Eilers M, Moroy T (1997) Mutual requirement of CDK4 and Myc in malignant transformation: evidence for cyclin D1/CDK4 and p16INK4A as upstream regulators of Myc. Oncogene 15(2):179–192. doi:10.1038/sj.onc.1201171
    • (1997) Oncogene , vol.15 , Issue.2 , pp. 179-192
    • Haas, K.1    Staller, P.2    Geisen, C.3    Bartek, J.4    Eilers, M.5    Moroy, T.6
  • 31
    • 0034135920 scopus 로고    scopus 로고
    • Expression of p19INK4d, CDK4, CDK6 in glioblastoma multiforme
    • COI: 1:STN:280:DC%2BD3czktlaqtw%3D%3D, PID: 10884881
    • Lam PY, Di Tomaso E, Ng HK, Pang JC, Roussel MF, Hjelm NM (2000) Expression of p19INK4d, CDK4, CDK6 in glioblastoma multiforme. Br J Neurosurg 14(1):28–32
    • (2000) Br J Neurosurg , vol.14 , Issue.1 , pp. 28-32
    • Lam, P.Y.1    Di Tomaso, E.2    Ng, H.K.3    Pang, J.C.4    Roussel, M.F.5    Hjelm, N.M.6
  • 32
    • 0032849353 scopus 로고    scopus 로고
    • Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity
    • COI: 1:CAS:528:DyaK1MXmtlals7c%3D, PID: 10490638
    • Tsutsui T, Hesabi B, Moons DS, Pandolfi PP, Hansel KS, Koff A, Kiyokawa H (1999) Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity. Mol Cell Biol 19(10):7011–7019
    • (1999) Mol Cell Biol , vol.19 , Issue.10 , pp. 7011-7019
    • Tsutsui, T.1    Hesabi, B.2    Moons, D.S.3    Pandolfi, P.P.4    Hansel, K.S.5    Koff, A.6    Kiyokawa, H.7
  • 33
    • 84863306358 scopus 로고    scopus 로고
    • Differential expression of 2′,3′-cyclic-nucleotide 3′-phosphodiesterase and neural lineage markers correlate with glioblastoma xenograft infiltration and patient survival
    • COI: 1:CAS:528:DC%2BC38XpvVOjtLk%3D
    • Zorniak M, Clark PA, Leeper HE, Tipping MD, Francis DM, Kozak KR, Salamat MS, Kuo JS (2012) Differential expression of 2′,3′-cyclic-nucleotide 3′-phosphodiesterase and neural lineage markers correlate with glioblastoma xenograft infiltration and patient survival. Clinical Cancer Res 18(13):3628–3636. doi:10.1158/1078-0432.CCR-12-0339
    • (2012) Clinical Cancer Res , vol.18 , Issue.13 , pp. 3628-3636
    • Zorniak, M.1    Clark, P.A.2    Leeper, H.E.3    Tipping, M.D.4    Francis, D.M.5    Kozak, K.R.6    Salamat, M.S.7    Kuo, J.S.8
  • 34
    • 21444458625 scopus 로고    scopus 로고
    • Endothelin receptor B is required for the expansion of melanocyte precursors and malignant melanoma
    • Lahav R (2005) Endothelin receptor B is required for the expansion of melanocyte precursors and malignant melanoma. Int J Dev Biol 49(2–3):173–180
    • (2005) Int J Dev Biol , vol.49 , Issue.2-3 , pp. 173-180
    • Lahav, R.1
  • 35
    • 27744484054 scopus 로고    scopus 로고
    • The natural history of EGFR and EGFRvIII in glioblastoma patients
    • PID: 16236164
    • Heimberger AB, Suki D, Yang D, Shi W, Aldape K (2005) The natural history of EGFR and EGFRvIII in glioblastoma patients. J Transl Med 3:38. doi:10.1186/1479-5876-3-38
    • (2005) J Transl Med , vol.3 , pp. 38
    • Heimberger, A.B.1    Suki, D.2    Yang, D.3    Shi, W.4    Aldape, K.5
  • 36
    • 81255178615 scopus 로고    scopus 로고
    • Arsenic, cadmium and neuron specific enolase (ENO2, gamma-enolase) expression in breast cancer
    • COI: 1:CAS:528:DC%2BC38Xms1CltQ%3D%3D, PID: 22098917
    • Soh MA, Garrett SH, Somji S, Dunlevy JR, Zhou XD, Sens MA, Bathula CS, Allen C, Sens DA (2011) Arsenic, cadmium and neuron specific enolase (ENO2, gamma-enolase) expression in breast cancer. Cancer Cell Int 11(1):41. doi:10.1186/1475-2867-11-41
    • (2011) Cancer Cell Int , vol.11 , Issue.1 , pp. 41
    • Soh, M.A.1    Garrett, S.H.2    Somji, S.3    Dunlevy, J.R.4    Zhou, X.D.5    Sens, M.A.6    Bathula, C.S.7    Allen, C.8    Sens, D.A.9
  • 38
    • 70350180734 scopus 로고    scopus 로고
    • Microtubule-associated protein tau in human prostate cancer cells: isoforms, phosphorylation, and interactions
    • COI: 1:CAS:528:DC%2BD1MXhtFyntLbM, PID: 19681044
    • Souter S, Lee G (2009) Microtubule-associated protein tau in human prostate cancer cells: isoforms, phosphorylation, and interactions. J Cell Biochem 108(3):555–564. doi:10.1002/jcb.22287
    • (2009) J Cell Biochem , vol.108 , Issue.3 , pp. 555-564
    • Souter, S.1    Lee, G.2
  • 43
    • 0035133842 scopus 로고    scopus 로고
    • Promoter hypermethylation of the RB1 gene in glioblastomas
    • COI: 1:CAS:528:DC%2BD3MXht1Sht7w%3D, PID: 11204276
    • Nakamura M, Yonekawa Y, Kleihues P, Ohgaki H (2001) Promoter hypermethylation of the RB1 gene in glioblastomas. Lab Invest 81(1):77–82
    • (2001) Lab Invest , vol.81 , Issue.1 , pp. 77-82
    • Nakamura, M.1    Yonekawa, Y.2    Kleihues, P.3    Ohgaki, H.4
  • 44
    • 0021332973 scopus 로고
    • Retinoblastoma: clues to human oncogenesis
    • COI: 1:STN:280:DyaL2c7itFeiug%3D%3D, PID: 6320372
    • Murphree AL, Benedict WF (1984) Retinoblastoma: clues to human oncogenesis. Science 223(4640):1028–1033
    • (1984) Science , vol.223 , Issue.4640 , pp. 1028-1033
    • Murphree, A.L.1    Benedict, W.F.2
  • 45
    • 71549120715 scopus 로고    scopus 로고
    • Glioblastoma proto-oncogene SEC61gamma is required for tumor cell survival and response to endoplasmic reticulum stress
    • COI: 1:CAS:528:DC%2BD1MXhsV2itLnL, PID: 19920201
    • Lu Z, Zhou L, Killela P, Rasheed AB, Di C, Poe WE, McLendon RE, Bigner DD, Nicchitta C, Yan H (2009) Glioblastoma proto-oncogene SEC61gamma is required for tumor cell survival and response to endoplasmic reticulum stress. Cancer Res 69(23):9105–9111. doi:10.1158/0008-5472.CAN-09-2775
    • (2009) Cancer Res , vol.69 , Issue.23 , pp. 9105-9111
    • Lu, Z.1    Zhou, L.2    Killela, P.3    Rasheed, A.B.4    Di, C.5    Poe, W.E.6    McLendon, R.E.7    Bigner, D.D.8    Nicchitta, C.9    Yan, H.10
  • 46
    • 59849125142 scopus 로고    scopus 로고
    • SOX2 silencing in glioblastoma tumor-initiating cells causes stop of proliferation and loss of tumorigenicity
    • COI: 1:CAS:528:DC%2BD1MXisVeqsbo%3D, PID: 18948646
    • Gangemi RM, Griffero F, Marubbi D, Perera M, Capra MC, Malatesta P, Ravetti GL, Zona GL, Daga A, Corte G (2009) SOX2 silencing in glioblastoma tumor-initiating cells causes stop of proliferation and loss of tumorigenicity. Stem Cells 27(1):40–48. doi:10.1634/stemcells.2008-0493
    • (2009) Stem Cells , vol.27 , Issue.1 , pp. 40-48
    • Gangemi, R.M.1    Griffero, F.2    Marubbi, D.3    Perera, M.4    Capra, M.C.5    Malatesta, P.6    Ravetti, G.L.7    Zona, G.L.8    Daga, A.9    Corte, G.10
  • 47
    • 77956547097 scopus 로고    scopus 로고
    • Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells
    • COI: 1:CAS:528:DC%2BC3cXhtFGjt7zM, PID: 20832727
    • Iliopoulos D, Lindahl-Allen M, Polytarchou C, Hirsch HA, Tsichlis PN, Struhl K (2010) Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells. Mol Cell 39(5):761–772. doi:10.1016/j.molcel.2010.08.013
    • (2010) Mol Cell , vol.39 , Issue.5 , pp. 761-772
    • Iliopoulos, D.1    Lindahl-Allen, M.2    Polytarchou, C.3    Hirsch, H.A.4    Tsichlis, P.N.5    Struhl, K.6
  • 49
    • 34250796207 scopus 로고    scopus 로고
    • Actin-binding proteins coronin-1a and IBA-1 are effective microglial markers for immunohistochemistry
    • COI: 1:CAS:528:DC%2BD2sXmvFahurg%3D, PID: 17341475
    • Ahmed Z, Shaw G, Sharma VP, Yang C, McGowan E, Dickson DW (2007) Actin-binding proteins coronin-1a and IBA-1 are effective microglial markers for immunohistochemistry. J Histochem Cytochem 55(7):687–700. doi:10.1369/jhc.6A7156.2007
    • (2007) J Histochem Cytochem , vol.55 , Issue.7 , pp. 687-700
    • Ahmed, Z.1    Shaw, G.2    Sharma, V.P.3    Yang, C.4    McGowan, E.5    Dickson, D.W.6
  • 50
    • 0027988669 scopus 로고
    • Essential involvement of interleukin-8 (IL-8) in acute inflammation
    • COI: 1:CAS:528:DyaK2cXmvFymtbo%3D, PID: 7964163
    • Harada A, Sekido N, Akahoshi T, Wada T, Mukaida N, Matsushima K (1994) Essential involvement of interleukin-8 (IL-8) in acute inflammation. J Leukoc Biol 56(5):559–564
    • (1994) J Leukoc Biol , vol.56 , Issue.5 , pp. 559-564
    • Harada, A.1    Sekido, N.2    Akahoshi, T.3    Wada, T.4    Mukaida, N.5    Matsushima, K.6
  • 51
    • 36348941771 scopus 로고    scopus 로고
    • PECAM-1: a multi-functional molecule in inflammation and vascular biology
    • COI: 1:CAS:528:DC%2BD2sXhtlahtLzE, PID: 17872453
    • Woodfin A, Voisin MB, Nourshargh S (2007) PECAM-1: a multi-functional molecule in inflammation and vascular biology. Arterioscler Thromb Vasc Biol 27(12):2514–2523. doi:10.1161/ATVBAHA.107.151456
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , Issue.12 , pp. 2514-2523
    • Woodfin, A.1    Voisin, M.B.2    Nourshargh, S.3
  • 53
    • 0025259548 scopus 로고
    • Cell proliferation patterns in the diagnosis of astrocytomas, anaplastic astrocytomas and glioblastoma multiforme: a Ki-67 study
    • COI: 1:STN:280:DyaK3c3msFCmug%3D%3D, PID: 2161084
    • Raghavan R, Steart PV, Weller RO (1990) Cell proliferation patterns in the diagnosis of astrocytomas, anaplastic astrocytomas and glioblastoma multiforme: a Ki-67 study. Neuropathol Appl Neurobiol 16(2):123–133
    • (1990) Neuropathol Appl Neurobiol , vol.16 , Issue.2 , pp. 123-133
    • Raghavan, R.1    Steart, P.V.2    Weller, R.O.3
  • 54
    • 84860393157 scopus 로고    scopus 로고
    • Minichromosome maintenance 2 (MCM2) is a new prognostic proliferative marker in Wilms tumour
    • PID: 21866463
    • Taran K, Sitkiewicz A, Andrzejewska E, Kobos J (2011) Minichromosome maintenance 2 (MCM2) is a new prognostic proliferative marker in Wilms tumour. Pol J Pathol 62(2):84–88
    • (2011) Pol J Pathol , vol.62 , Issue.2 , pp. 84-88
    • Taran, K.1    Sitkiewicz, A.2    Andrzejewska, E.3    Kobos, J.4
  • 56
    • 25144440471 scopus 로고    scopus 로고
    • Reactive astrocytes in neural repair and protection
    • COI: 1:CAS:528:DC%2BD2MXhtFegtb3M, PID: 16151042
    • Sofroniew MV (2005) Reactive astrocytes in neural repair and protection. Neuroscientist 11(5):400–407. doi:10.1177/1073858405278321
    • (2005) Neuroscientist , vol.11 , Issue.5 , pp. 400-407
    • Sofroniew, M.V.1
  • 57
    • 0037440416 scopus 로고    scopus 로고
    • Endothelin B receptors are expressed by astrocytes and regulate astrocyte hypertrophy in the normal and injured CNS
    • PID: 12509808
    • Rogers SD, Peters CM, Pomonis JD, Hagiwara H, Ghilardi JR, Mantyh PW (2003) Endothelin B receptors are expressed by astrocytes and regulate astrocyte hypertrophy in the normal and injured CNS. Glia 41(2):180–190. doi:10.1002/glia.10173
    • (2003) Glia , vol.41 , Issue.2 , pp. 180-190
    • Rogers, S.D.1    Peters, C.M.2    Pomonis, J.D.3    Hagiwara, H.4    Ghilardi, J.R.5    Mantyh, P.W.6
  • 59
    • 33644778697 scopus 로고    scopus 로고
    • Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivo
    • COI: 1:CAS:528:DC%2BD28XksF2kt7k%3D, PID: 16492744
    • Francoz S, Froment P, Bogaerts S, De Clercq S, Maetens M, Doumont G, Bellefroid E, Marine JC (2006) Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivo. Proc Natl Acad Sci USA 103(9):3232–3237. doi:10.1073/pnas.0508476103
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.9 , pp. 3232-3237
    • Francoz, S.1    Froment, P.2    Bogaerts, S.3    De Clercq, S.4    Maetens, M.5    Doumont, G.6    Bellefroid, E.7    Marine, J.C.8
  • 61
    • 0025182875 scopus 로고
    • Prognostic implications of glial fibrillary acidic protein containing cell types in oligodendrogliomas
    • COI: 1:STN:280:DyaK3czotFKntA%3D%3D, PID: 2205356
    • Kros JM, Van Eden CG, Stefanko SZ, Waayer-Van Batenburg M, van der Kwast TH (1990) Prognostic implications of glial fibrillary acidic protein containing cell types in oligodendrogliomas. Cancer 66(6):1204–1212
    • (1990) Cancer , vol.66 , Issue.6 , pp. 1204-1212
    • Kros, J.M.1    Van Eden, C.G.2    Stefanko, S.Z.3    Waayer-Van Batenburg, M.4    van der Kwast, T.H.5
  • 62
    • 0025257365 scopus 로고
    • An immunocytochemical comparison of glial fibrillary acidic protein, S-100p and vimentin in human glial tumors
    • COI: 1:STN:280:DyaK3c3gtl2lsQ%3D%3D, PID: 2319288
    • Nakopoulou L, Kerezoudi E, Thomaides T, Litsios B (1990) An immunocytochemical comparison of glial fibrillary acidic protein, S-100p and vimentin in human glial tumors. J Neurooncol 8(1):33–40
    • (1990) J Neurooncol , vol.8 , Issue.1 , pp. 33-40
    • Nakopoulou, L.1    Kerezoudi, E.2    Thomaides, T.3    Litsios, B.4
  • 64
    • 70349304188 scopus 로고    scopus 로고
    • Evaluation of microtubule-associated protein-Tau expression as a prognostic and predictive marker in the NSABP-B 28 randomized clinical trial
    • COI: 1:CAS:528:DC%2BD1MXht1WisbjJ, PID: 19667268
    • Pusztai L, Jeong JH, Gong Y, Ross JS, Kim C, Paik S, Rouzier R, Andre F, Hortobagyi GN, Wolmark N, Symmans WF (2009) Evaluation of microtubule-associated protein-Tau expression as a prognostic and predictive marker in the NSABP-B 28 randomized clinical trial. J Clin Oncol 27(26):4287–4292. doi:10.1200/JCO.2008.21.6887
    • (2009) J Clin Oncol , vol.27 , Issue.26 , pp. 4287-4292
    • Pusztai, L.1    Jeong, J.H.2    Gong, Y.3    Ross, J.S.4    Kim, C.5    Paik, S.6    Rouzier, R.7    Andre, F.8    Hortobagyi, G.N.9    Wolmark, N.10    Symmans, W.F.11
  • 65
    • 75049085498 scopus 로고    scopus 로고
    • Differential expression of Notch family members in astrocytomas and medulloblastomas
    • COI: 1:CAS:528:DC%2BD1MXhsFyjsL3E, PID: 19424825
    • Xu P, Yu S, Jiang R, Kang C, Wang G, Jiang H, Pu P (2009) Differential expression of Notch family members in astrocytomas and medulloblastomas. Pathol Oncol Res 15(4):703–710. doi:10.1007/s12253-009-9173-x
    • (2009) Pathol Oncol Res , vol.15 , Issue.4 , pp. 703-710
    • Xu, P.1    Yu, S.2    Jiang, R.3    Kang, C.4    Wang, G.5    Jiang, H.6    Pu, P.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.