Recurrence and cancer-specific survival according to the expression of IL-4Rα and IL-13Rα1 in patients with oral cavity cancer

European Journal of Cancer

Volumn 51, Issue 2, 2015, Pages 177-185

  Kwon, Minsu ^a   Kim, Ji Won ^a   Roh, Jong Lyel ^a   Park, Yangsoon ^a   Cho, Kyung Ja ^a   Choi, Seung Ho ^a   Nam, Soon Yuhl ^a   Kim, Sang Yoon ^a,b   Lee, Byung Heon ^c  

^a University of Ulsan College of Medicine   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

^c Kyungpook National University School of Medicine   (South Korea)

Author keywords

Interleukin 13 receptor; Interleukin 4 receptor; Oral cavity squamous cell carcinoma; Recurrence; Survival

Indexed keywords

INTERLEUKIN 3 RECEPTOR ALPHA 1; INTERLEUKIN 4 RECEPTOR ALPHA; INTERLEUKIN RECEPTOR; UNCLASSIFIED DRUG; INTERLEUKIN 13 RECEPTOR ALPHA1;

ADULT; AGED; ARTICLE; CANCER RECURRENCE; CANCER RISK; CANCER SPECIFIC SURVIVAL; CANCER STAGING; CLINICAL EXAMINATION; CONTROLLED STUDY; FEMALE; FOLLOW UP; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; MALE; MOUTH SQUAMOUS CELL CARCINOMA; PRIMARY TUMOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADICAL RESECTION; SECOND CANCER; TUMOR VOLUME; BIOSYNTHESIS; CARCINOMA, SQUAMOUS CELL; KAPLAN MEIER METHOD; METABOLISM; MIDDLE AGED; MOUTH NEOPLASMS; MULTIVARIATE ANALYSIS; OUTCOME ASSESSMENT; PATHOLOGY; PROCEDURES; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; STATISTICS AND NUMERICAL DATA; TUMOR RECURRENCE; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; FOLLOW-UP STUDIES; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-13 RECEPTOR ALPHA1 SUBUNIT; INTERLEUKIN-4 RECEPTOR ALPHA SUBUNIT; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; MOUTH NEOPLASMS; MULTIVARIATE ANALYSIS; NEOPLASM RECURRENCE, LOCAL; OUTCOME ASSESSMENT (HEALTH CARE); PROGNOSIS; PROPORTIONAL HAZARDS MODELS; YOUNG ADULT;

EID: 84925449445     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2014.11.010     Document Type: Article

References (24)

1. M.A. Hallett, K.T. Venmar, and B. Fingleton Cytokine stimulation of epithelial cancer cells: the similar and divergent functions of IL-4 and IL-13 Cancer Res 72 2012 6338 6343
2. W.E. Paul Interleukin-4: a prototypic immunoregulatory lymphokine Blood 77 1991 1859 1870
3. S.L. LaPorte, Z.S. Juo, and J. Vaclavikova Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system Cell 132 2008 259 272
4. F.L. Koller, D.G. Hwang, E.A. Dozier, and B. Fingleton Epithelial interleukin-4 receptor expression promotes colon tumor growth Carcinogenesis 31 2010 1010 1017
5. A. Formentini, O. Prokopchuk, and J. Strater Interleukin-13 exerts autocrine growth-promoting effects on human pancreatic cancer, and its expression correlates with a propensity for lymph node metastases Int J Colorectal Dis 24 2009 57 67
6. A. Formentini, P. Braun, and H. Fricke Expression of interleukin-4 and interleukin-13 and their receptors in colorectal cancer Int J Colorectal Dis 27 2012 1369 1376
7. M. Todaro, Y. Lombardo, and M.G. Francipane Apoptosis resistance in epithelial tumors is mediated by tumor-cell-derived interleukin-4 Cell Death Differ 15 2008 762 772
8. D.C. Altieri Survivin, cancer networks and pathway-directed drug discovery Nat Rev Cancer 8 2008 61 70
9. M. Wills-Karp, and F.D. Finkelman Untangling the complex web of IL-4- and IL-13-mediated signaling pathways Sci Signal 1 2008 pe55
10. D.M. Lathers, and M.R. Young Increased aberrance of cytokine expression in plasma of patients with more advanced squamous cell carcinoma of the head and neck Cytokine 25 2004 220 228
11. S. Trellakis, K. Bruderek, and C.A. Dumitru Polymorphonuclear granulocytes in human head and neck cancer: enhanced inflammatory activity, modulation by cancer cells and expansion in advanced disease Int J Cancer 129 2011 2183 2193
12. W.K. Mydlarz, P.T. Hennessey, and H. Wang Serum biomarkers for detection of head and neck squamous cell carcinoma Head Neck 2014 [Epub ahead of print]
13. S.B. Edge, D.R. Byrd, and C.C. Compton AJCC cancer staging manual 2010 Springer-Verlag New York
14. C. Bleotu, M.C. Chifiriuc, and R. Grigore Investigation of Th1/Th2 cytokine profiles in patients with laryngo-pharyngeal, HPV-positive cancers Eur Arch Otorhinolaryngol 270 2013 711 718
15. K. Kawakami, P. Leland, and R.K. Puri Structure, function, and targeting of interleukin 4 receptors on human head and neck cancer cells Cancer Res 60 2000 2981 2987
16. C.W. Ko, R.J. Cuthbert, and N.M. Orsi Lack of interleukin-4 receptor alpha chain-dependent signalling promotes azoxymethane-induced colorectal aberrant crypt focus formation in Balb/c mice J Pathol 214 2008 603 609
17. N. Ingram, E.L. Northwood, and S.L. Perry Reduced type II interleukin-4 receptor signalling drives initiation, but not progression, of colorectal carcinogenesis: evidence from transgenic mouse models and human case-control epidemiological observations Carcinogenesis 34 2013 2341 2349
18. K. Seto, J. Shoda, and T. Horibe Interleukin-4 receptor alpha-based hybrid peptide effectively induces antitumor activity in head and neck squamous cell carcinoma Oncol Rep 29 2013 2147 2153
19. M. Terabe, S. Matsui, and N. Noben-Trauth NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway Nat Immunol 1 2000 515 520
20. R. Barderas, R.A. Bartolome, and M.J. Fernandez-Acenero High expression of IL-13 receptor alpha2 in colorectal cancer is associated with invasion, liver metastasis, and poor prognosis Cancer Res 72 2012 2780 2790
21. V. Nguyen, J.M. Conyers, and D. Zhu IL-13Rα2-targeted therapy escapees: biologic and therapeutic implications Transl Oncol 4 2011 390 400
22. H. Serve, E. Oelmann, and A. Herweg Inhibition of proliferation and clonal growth of human breast cancer cells by interleukin 13 Cancer Res 56 1996 3583 3588
23. N.I. Obiri, S.R. Husain, W. Debinski, and R.K. Puri Interleukin 13 inhibits growth of human renal cell carcinoma cells independently of the p140 interleukin 4 receptor chain Clin Cancer Res 2 1996 1743 1749
24. H.L. Ma, M.J. Whitters, and B.A. Jacobson Tumor cells secreting IL-13 but not IL-13Rα2 fusion protein have reduced tumorigenicity in vivo Int Immunol 16 2004 1009 1017